Enmein (BioDeep_00000000944)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C20H26O6 (362.1729)
中文名称: 延命草素
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 80.36%
分子结构信息
SMILES: C=C1C(=O)C23CC1CCC2C12COC(O)C1C(C)(C)C(O)CC2OC3=O
InChI: InChI=1S/C20H26O6/c1-9-10-4-5-11-19(7-10,15(9)22)17(24)26-13-6-12(21)18(2,3)14-16(23)25-8-20(11,13)14/h10-14,16,21,23H,1,4-8H2,2-3H3/t10-,11-,12+,13+,14-,16-,19+,20-/m1/s1
描述信息
Enmein is a delta-lactone. It has a role as a metabolite.
Enmein is a natural product found in Isodon oresbius, Isodon serra, and other organisms with data available.
A natural product found in Isodon eriocalyx.
同义名列表
7 个代谢物同义名
(1S,4S,6S,8R,9R,12S,13S,16R)-6,9-dihydroxy-7,7-dimethyl-17-methylidene-3,10-dioxapentacyclo[14.2.1.01,13.04,12.08,12]nonadecane-2,18-dione; 2,13-Dihydroxy-1,1-dimethyl-7-methylidenedecahydro-5H,11H-5a,8-methanocyclohepta[c]furo[3,4-e][1]benzopyran-5,6(7H)-dione; Sculponeatin D; Enmein; Enemin; AKOS032949119; Enmein
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:70378
- KEGG: C09090
- PubChem: 352542
- PubChem: 3721623
- Metlin: METLIN67419
- ChEMBL: CHEMBL453801
- MeSH: enmein
- CAS: 3776-39-4
- medchemexpress: HY-N5028
- PMhub: MS000020441
- MetaboLights: MTBLC70378
- PubChem: 11282
- KNApSAcK: C00003424
- 3DMET: B02675
- NIKKAJI: J37.139D
- KNApSAcK: 70378
- LOTUS: LTS0198307
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
46 个相关的物种来源信息
- 6656 - Arthropoda: LTS0198307
- 2759 - Eukaryota: LTS0198307
- 50557 - Insecta: LTS0198307
- 204130 - Isodon: 10.1016/S0031-9422(01)00245-X
- 204130 - Isodon: LTS0198307
- 662907 - Isodon eriocalyx:
- 662907 - Isodon eriocalyx: 10.1016/S0031-9422(97)00418-4
- 662907 - Isodon eriocalyx: 10.1021/NP1004328
- 662907 - Isodon eriocalyx: LTS0198307
- 425908 - Isodon japonicus:
- 425908 - Isodon japonicus: 10.1016/J.PHYTOCHEM.2004.02.022
- 425908 - Isodon japonicus: 10.1016/S0031-9422(01)00245-X
- 425908 - Isodon japonicus: 10.1016/S0040-4020(01)97055-3
- 425908 - Isodon japonicus: 10.1016/S0367-326X(03)00107-2
- 425908 - Isodon japonicus: 10.1271/BBB1961.48.1647
- 425908 - Isodon japonicus: LTS0198307
- 550456 - Isodon longitubus: 10.1021/NP50107A015
- 550456 - Isodon longitubus: LTS0198307
- 204133 - Isodon lophanthoides: 10.1016/0031-9422(89)85035-6
- 204133 - Isodon lophanthoides: LTS0198307
- 1504648 - Isodon oresbius:
- 1504648 - Isodon oresbius: 10.1016/J.PHYTOCHEM.2004.02.022
- 1504648 - Isodon oresbius: 10.1016/S0031-9422(00)90740-4
- 1504648 - Isodon oresbius: LTS0198307
- 662928 - Isodon sculponeatus:
- 662928 - Isodon sculponeatus: 10.1002/CBDV.200900302
- 662928 - Isodon sculponeatus: 10.1002/CHIN.200624175
- 662928 - Isodon sculponeatus: 10.1021/NP400669T
- 662928 - Isodon sculponeatus: 10.1021/NP900406C
- 662928 - Isodon sculponeatus: 10.1248/CPB.57.525
- 662928 - Isodon sculponeatus: LTS0198307
- 199544 - Isodon serra:
- 199544 - Isodon serra: 10.1002/HLCA.200490281
- 199544 - Isodon serra: 10.3184/030823407X225536
- 199544 - Isodon serra: LTS0198307
- 425909 - Isodon trichocarpus:
- 425909 - Isodon trichocarpus: 10.1039/P19860000689
- 425909 - Isodon trichocarpus: 10.1248/CPB.42.922
- 425909 - Isodon trichocarpus: 10.1248/YAKUSHI1947.87.9_1150
- 425909 - Isodon trichocarpus: LTS0198307
- 4136 - Lamiaceae: LTS0198307
- 3398 - Magnoliopsida: LTS0198307
- 7055 - Scarabaeidae: LTS0198307
- 35493 - Streptophyta: LTS0198307
- 58023 - Tracheophyta: LTS0198307
- 33090 - Viridiplantae: LTS0198307
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Seiji Tanaka, Michiho Ito. Quantitative Analysis of Ent-Kaurane Diterpenoids in Isodon Herb (Enmei-So) by HPLC-UV.
Chemical & pharmaceutical bulletin.
2021; 69(3):246-252. doi:
10.1248/cpb.c20-00769. [PMID: 33642472] - Dahong Li, Xu Hu, Tong Han, Jie Liao, Wei Xiao, Shengtao Xu, Zhanlin Li, Zhenzhong Wang, Huiming Hua, Jinyi Xu. NO-Releasing Enmein-Type Diterpenoid Derivatives with Selective Antiproliferative Activity and Effects on Apoptosis-Related Proteins.
Molecules (Basel, Switzerland).
2016 Sep; 21(9):. doi:
10.3390/molecules21091193. [PMID: 27617998] - Jin Yang, Wei-Guang Wang, Hai-Yan Wu, Xue Du, Xiao-Nian Li, Yan Li, Jian-Xin Pu, Han-Dong Sun. Bioactive Enmein-Type ent-Kaurane Diterpenoids from Isodon phyllostachys.
Journal of natural products.
2016 Jan; 79(1):132-40. doi:
10.1021/acs.jnatprod.5b00802. [PMID: 26757019] - Tao Wang, Yi fang Wu, Xue liang Wang. Molecular structure and vibrational bands and 13C chemical shift assignments of both enmein-type diterpenoids by DFT study.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Jan; 117(?):449-58. doi:
10.1016/j.saa.2013.08.010. [PMID: 24013676] - Hua-Yi Jiang, Wei-Guang Wang, Min Zhou, Hai-Yan Wu, Rui Zhan, Xiao-Nian Li, Xue Du, Yan Li, Jian-Xin Pu, Han-Dong Sun. Enmein-type 6,7-seco-ent-kauranoids from Isodon sculponeatus.
Journal of natural products.
2013 Nov; 76(11):2113-9. doi:
10.1021/np400669t. [PMID: 24219809] - Xu Liu, Wei-Guang Wang, Xue Du, Xiao-Nian Li, Ling-Mei Kong, Yan Li, Jian-Xin Pu, Ji-Zhou Wu, Han-Dong Sun. Enmein-type diterpenoids from the aerial parts of Isodon rubescens and their cytotoxicity.
Fitoterapia.
2012 Dec; 83(8):1451-5. doi:
10.1016/j.fitote.2012.08.009. [PMID: 22926044] - Li-Mei Li, Guo-You Li, Jian-Xin Pu, Wei-Lie Xiao, Li-Sheng Ding, Han-Dong Sun. ent-Kaurane and cembrane diterpenoids from Isodon sculponeatus and their cytotoxicity.
Journal of natural products.
2009 Oct; 72(10):1851-6. doi:
10.1021/np900406c. [PMID: 19697926] - Yan Zhou, Bin-Li Yang, Jing Yang, Sheng-Xiong Huang, Han-Dong Sun, Hong-Xi Xu, Li-Sheng Ding. Electrospray ionization tandem mass spectrometric analysis of ent-6,7-seco-kaurane diterpenoids from the Isodon species.
Rapid communications in mass spectrometry : RCM.
2009 Jan; 23(1):138-46. doi:
10.1002/rcm.3864. [PMID: 19072746] - Takuro Maruyama, Naoki Sugimoto, Masanori Kuroyanagi, Ik Hwi Kim, Hiroyuki Kamakura, Takeshi Kawasaki, Masao Fujita, Hiroshi Shimada, Yutaka Yamamoto, Atsuko Tada, Takeshi Yamazaki, Yukihiro Goda. Authentication and chemical study of isodonis herba and isodonis extracts.
Chemical & pharmaceutical bulletin.
2007 Nov; 55(11):1626-30. doi:
10.1248/cpb.55.1626. [PMID: 17978524] - S Kadota, P Basnet, E Ishii, T Tamura, T Namba. Antibacterial activity of trichorabdal A from Rabdosia trichocarpa against Helicobacter pylori.
Zentralblatt fur Bakteriologie : international journal of medical microbiology.
1997 Jun; 286(1):63-7. doi:
10.1016/s0934-8840(97)80076-x. [PMID: 9241802]
