Pifithrin-Beta (BioDeep_00000008729)

   


代谢物信息卡片


2-p-Tolyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole

化学式: C16H16N2S (268.1034)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2
InChI: InChI=1S/C16H16N2S/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13/h6-10H,2-5H2,1H3

描述信息

同义名列表

2 个代谢物同义名

Pifithrin-Beta; 2-p-Tolyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 AHR, ATG5, BECN1, CASP3, CDC25C, DCTN4, DRAM1, MAPK14, MAPK8, MAPK9, MTOR, PLK1, S100B, SIRT1, TUBB4B
Golgi apparatus, trans-Golgi network membrane 1 BECN1
Peripheral membrane protein 3 ATG5, BECN1, MTOR
Endosome membrane 1 BECN1
Endoplasmic reticulum membrane 3 BECN1, CD59, MTOR
Mitochondrion membrane 1 BECN1
Cytoplasmic vesicle, autophagosome 1 BECN1
Nucleus 13 AHR, BECN1, CASP3, CDC25C, DCTN4, MAPK14, MAPK8, MAPK9, MTOR, PLK1, S100B, SIRT1, TUBB4B
autophagosome 3 ATG5, BECN1, MAP1LC3A
cytosol 16 AHR, ATG5, BECN1, CASP3, CDC25C, DCTN4, MAP1LC3A, MAPK14, MAPK8, MAPK9, MTOR, PLK1, PRF1, S100B, SIRT1, TUBB4B
dendrite 2 BECN1, MTOR
mitochondrial membrane 1 BECN1
nuclear body 1 BECN1
phagocytic vesicle 2 BECN1, MTOR
phosphatidylinositol 3-kinase complex, class III 1 BECN1
trans-Golgi network 1 BECN1
centrosome 2 DCTN4, PLK1
nucleoplasm 10 AHR, CASP3, CDC25C, MAPK14, MAPK8, MAPK9, MTOR, PLK1, S100B, SIRT1
Cell membrane 2 CD59, PRF1
Lipid-anchor 1 MAP1LC3A
Cytoplasmic side 1 MTOR
Multi-pass membrane protein 3 DRAM1, PRF1, TPRA1
Golgi apparatus membrane 1 MTOR
Synapse 1 MAPK8
cell cortex 1 DCTN4
cell surface 1 CD59
glutamatergic synapse 4 ATG5, CASP3, MAP1LC3A, MAPK14
Golgi membrane 2 CD59, MTOR
lysosomal membrane 2 DRAM1, MTOR
neuronal cell body 2 CASP3, S100B
postsynapse 1 ATG5
Lysosome 2 DRAM1, MTOR
endosome 1 BECN1
plasma membrane 4 CD59, MAPK9, PRF1, TPRA1
Membrane 6 ATG5, CD59, DRAM1, MTOR, PRF1, TPRA1
axon 2 ATG5, MAPK8
extracellular exosome 2 CD59, TUBB4B
Lysosome membrane 2 DRAM1, MTOR
endoplasmic reticulum 1 BECN1
extracellular space 2 CD59, S100B
perinuclear region of cytoplasm 2 CDC25C, S100B
Schaffer collateral - CA1 synapse 2 ATG5, MAPK9
mitochondrion 3 MAPK14, MAPK9, SIRT1
protein-containing complex 2 AHR, ATG5
intracellular membrane-bounded organelle 2 MAP1LC3A, S100B
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
chromatin silencing complex 1 SIRT1
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 2 PRF1, S100B
extracellular region 4 MAPK14, PRF1, S100B, TUBB4B
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
transcription regulator complex 1 AHR
centriolar satellite 1 PLK1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 DCTN4, PLK1
external side of plasma membrane 1 CD59
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 2 PLK1, TUBB4B
nucleolus 1 SIRT1
midbody 1 PLK1
spindle midzone 1 PLK1
vesicle 1 CD59
heterochromatin 1 SIRT1
Cytoplasm, cytoskeleton 3 DCTN4, MAP1LC3A, TUBB4B
Cytoplasm, cytoskeleton, spindle 1 PLK1
focal adhesion 2 CD59, DCTN4
microtubule 2 MAP1LC3A, TUBB4B
spindle 1 PLK1
Nucleus, PML body 2 MTOR, SIRT1
PML body 2 MTOR, SIRT1
mitochondrial intermembrane space 1 CDC25C
axoneme 1 ATG5
nuclear speck 2 MAPK14, MAPK9
nuclear inner membrane 1 SIRT1
Cytoplasm, myofibril, sarcomere 1 DCTN4
Late endosome 1 MAP1LC3A
ruffle 1 S100B
sarcomere 1 DCTN4
chromatin 3 AHR, PLK1, SIRT1
Cytoplasmic vesicle, autophagosome membrane 1 MAP1LC3A
autophagosome membrane 1 MAP1LC3A
phagocytic vesicle membrane 1 ATG5
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
centriole 1 PLK1
spindle pole 3 DCTN4, MAPK14, PLK1
Cytoplasm, cell cortex 1 DCTN4
Lipid-anchor, GPI-anchor 1 CD59
organelle membrane 1 MAP1LC3A
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
fibrillar center 1 SIRT1
nuclear envelope 2 MTOR, SIRT1
Endomembrane system 3 DRAM1, MAP1LC3A, MTOR
endosome lumen 1 PRF1
axonemal microtubule 1 TUBB4B
phagophore assembly site 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type I 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type II 1 BECN1
Preautophagosomal structure membrane 1 ATG5
Atg12-Atg5-Atg16 complex 1 ATG5
mitochondria-associated endoplasmic reticulum membrane contact site 1 ATG5
phagophore assembly site membrane 1 ATG5
aryl hydrocarbon receptor complex 1 AHR
specific granule membrane 1 CD59
tertiary granule membrane 1 CD59
euchromatin 1 SIRT1
side of membrane 1 CD59
stress fiber 1 DCTN4
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
dynactin complex 1 DCTN4
kinetochore 2 DCTN4, PLK1
mitotic spindle pole 1 PLK1
transport vesicle 1 CD59
azurophil granule lumen 1 TUBB4B
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 CD59
immunological synapse 1 PRF1
cytoplasmic dynein complex 1 DCTN4
ER to Golgi transport vesicle membrane 1 CD59
outer kinetochore 1 PLK1
Cytoplasm, cytoskeleton, stress fiber 1 DCTN4
synaptonemal complex 1 PLK1
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
Cytoplasmic vesicle, phagosome 1 MTOR
transferase complex 1 ATG5
Autolysosome 1 MAP1LC3A
Cytolytic granule 1 PRF1
cytolytic granule lumen 1 PRF1
cytoplasmic side of mitochondrial outer membrane 1 BECN1
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
[Beclin-1-C 35 kDa]: Mitochondrion 1 BECN1
[Beclin-1-C 37 kDa]: Mitochondrion 1 BECN1
phagophore 1 ATG5
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

  • Wei-Feng Gui, Shuo Xu, Zhi-Sheng Dang, Yu-Min Zhao. In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis. The Journal of parasitology. 2019 02; 105(1):146-154. doi: 10.1645/18-121. [PMID: 30807708]