phorate (BioDeep_00000872525)

Main id: BioDeep_00000002357

 


代谢物信息卡片


6Z-8-Hydroxygeraniol 8-O-glucoside

化学式: C7H17O2PS3 (260.0128272)
中文名称: 甲拌磷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOP(=S)(OCC)SCSCC
InChI: InChI=1S/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3

描述信息

D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
Constituent of fresh ginger (Zingiber officinale). 6Z-8-Hydroxygeraniol 8-O-glucoside is found in herbs and spices.

同义名列表

2 个代谢物同义名

phorate; 6Z-8-Hydroxygeraniol 8-O-glucoside



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zhiwen Wei, Zuxin Dong, Juan Jia, Xinhua Liang, Tao Wang, Meng Hu, Shanlin Fu, Keming Yun. Application of Q-TOF-MS based metabonomics techniques to analyze the plasma metabolic profile changes on rats following death due to acute intoxication of phorate. International journal of legal medicine. 2021 Jul; 135(4):1437-1447. doi: 10.1007/s00414-021-02532-z. [PMID: 33987742]
  • Arun Ratn, Yashika Awasthi, Manoj Kumar, Sunil Kumar Singh, Renu Tripathi, Sunil P Trivedi. Phorate induced oxidative stress, DNA damage and differential expression of p53, apaf-1 and cat genes in fish, Channa punctatus (Bloch, 1793). Chemosphere. 2017 Sep; 182(?):382-391. doi: 10.1016/j.chemosphere.2017.05.008. [PMID: 28511133]
  • Roberto Busi, Todd Adam Gaines, Stephen Powles. Phorate can reverse P450 metabolism-based herbicide resistance in Lolium rigidum. Pest management science. 2017 Feb; 73(2):410-417. doi: 10.1002/ps.4441. [PMID: 27643926]
  • Xiaowei Sun, Wei Xu, Yan Zeng, Yurong Hou, Lin Guo, Xiujuan Zhao, Changhao Sun. Metabonomics evaluation of urine from rats administered with phorate under long-term and low-level exposure by ultra-performance liquid chromatography-mass spectrometry. Journal of applied toxicology : JAT. 2014 Feb; 34(2):176-83. doi: 10.1002/jat.2848. [PMID: 23280859]
  • Jindan Yang, Jie Cao, Xiaowei Sun, Zhijing Feng, Dongfang Hao, Xiujuan Zhao, Changhao Sun. Effects of long-term exposure to low levels of organophosphorous pesticides and their mixture on altered antioxidative defense mechanisms and lipid peroxidation in rat liver. Cell biochemistry and function. 2012 Mar; 30(2):122-8. doi: 10.1002/cbf.1825. [PMID: 22034174]
  • Quaiser Saquib, Sabry M Attia, Maqsood A Siddiqui, Mourad A M Aboul-Soud, Abdulaziz A Al-Khedhairy, John P Giesy, Javed Musarrat. Phorate-induced oxidative stress, DNA damage and transcriptional activation of p53 and caspase genes in male Wistar rats. Toxicology and applied pharmacology. 2012 Feb; 259(1):54-65. doi: 10.1016/j.taap.2011.12.006. [PMID: 22197610]
  • Quaiser Saquib, Abdulaziz A Al-Khedhairy, Maqsood A Siddiqui, Atanu Singha Roy, Swagata Dasgupta, Javed Musarrat. Preferential binding of insecticide phorate with sub-domain IIA of human serum albumin induces protein damage and its toxicological significance. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011 Aug; 49(8):1787-95. doi: 10.1016/j.fct.2011.04.028. [PMID: 21557983]
  • Hari C Meher, Vijay T Gajbhiye, Ghanendra Singh, Anju Kamra, Gautam Chawla. Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions. Journal of agricultural and food chemistry. 2010 Feb; 58(3):1815-22. doi: 10.1021/jf903609d. [PMID: 20085277]
  • Atef M Al-Attar. Physiological and histopathological investigations on the effects of alpha-lipoic acid in rats exposed to malathion. Journal of biomedicine & biotechnology. 2010; 2010(?):203503. doi: 10.1155/2010/203503. [PMID: 20454535]
  • D Ames Herbert, S Malone, S Aref, R L Brandenburg, D L Jordan, B M Royals, P D Johnson. Role of insecticides in reducing thrips injury to plants and incidence of tomato spotted wilt virus in Virginia market-type peanut. Journal of economic entomology. 2007 Aug; 100(4):1241-7. doi: 10.1603/0022-0493(2007)100[1241:roiirt]2.0.co;2. [PMID: 17849876]
  • Thaysa Paschoalin, Adriana K Carmona, Elaine G Rodrigues, Vitor Oliveira, Hugo P Monteiro, Maria A Juliano, Luiz Juliano, Luiz R Travassos. Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth. Molecular cancer. 2007 Jul; 6(?):44. doi: 10.1186/1476-4598-6-44. [PMID: 17620116]
  • B Jyothi, G Narayan. Study of Serum Cholinesterase levels in fish Clarias batrachus (Linn.) exposed to pesticides carbaryl and phorate. Journal of environmental science & engineering. 2004 Oct; 46(4):274-6. doi: . [PMID: 16649625]
  • M Mohssen. Biochemical and histopathological changes in serum creatinine and kidney induced by inhalation of Thimet (Phorate) in male Swiss albino mouse, Mus musculus. Environmental research. 2001 Sep; 87(1):31-6. doi: 10.1006/enrs.2001.4285. [PMID: 11534962]
  • B Jyothi, G Narayan. Effect of pesticides carbaryl and phorate on serum cholesterol level in fish, Clarias batrachus (Linn). Journal of environmental biology. 2001 Jul; 22(3):233-5. doi: NULL. [PMID: 12017268]
  • B Jyothi, G Narayan. Pesticide induced alterations of non-protein nitrogenous constituents in the serum of a fresh water cat fish, Clarias batrachus (Linn.). Indian journal of experimental biology. 2000 Oct; 38(10):1058-61. doi: NULL. [PMID: 11324161]
  • A Singh, D K Singh, R A Agarwal. Effect of cypermethrin, mexacarbate, and phorate on phospholipid and lipid peroxidation in the snail Lymnaea acuminata. Bulletin of environmental contamination and toxicology. 1993 Jul; 51(1):68-71. doi: 10.1007/bf00201002. [PMID: 8318776]
  • S K Kashyap, J P Jani, H N Saiyed, S K Gupta. Clinical effects and cholinesterase activity changes in workers exposed to Phorate (Thimet). Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1984 Jun; 19(4-5):479-89. doi: 10.1080/03601238409372445. [PMID: 6470423]
  • C D Brokopp, J L Wyatt, J Gabica. Dialkyl phosphates in urine samples from pesticide formulators exposed to disulfoton and phorate. Bulletin of environmental contamination and toxicology. 1981 Apr; 26(4):524-9. doi: 10.1007/bf01622131. [PMID: 7236911]
  • D G Finlayson, I H Williams, M J Brown, C J Campbell. Distribution of insecticide residues in carrots at harvest. Journal of agricultural and food chemistry. 1976 May; 24(3):606-8. doi: 10.1021/jf60205a060. [PMID: 131814]
  • E P Lichtenstein, T W Fuhremann, K R Schulz. Translocation and metabolism of (14C)phorate as affected by percolating water in a model soil-plant ecosystem. Journal of agricultural and food chemistry. 1974 Nov; 22(6):991-6. doi: 10.1021/jf60196a034. [PMID: 4430812]
  • H R Krueger, J F Mason. Effects of plant growth regulators on levels of phorate and aldicarb in soybeans. Journal of agricultural and food chemistry. 1974 Mar; 22(2):338-9. doi: 10.1021/jf60192a023. [PMID: 4857669]
  • T Shafik, D E Bradway, H F Enos, A R Yobs. gas-liquid chromatographic analysis of alkyl phosphate metabolites in urine. Journal of agricultural and food chemistry. 1973 Jul; 21(4):625-9. doi: 10.1021/jf60188a036. [PMID: 4268895]
  • E E Burgess, H E Williams, R E Wilkinson, E A Heinrichs. Field tests of insecticides against Plagiotrochus cornigerus. Journal of economic entomology. 1972 Oct; 65(5):1484-5. doi: 10.1093/jee/65.5.1484. [PMID: 5085816]