Tetranap (BioDeep_00000869563)
代谢物信息卡片
InChI=1\C10H12\c1-2-6-10-8-4-3-7-9(10)5-1\h1-2,5-6H,3-4,7-8H
化学式: C10H12 (132.0939)
中文名称: 1,2,3,4-四氢萘, 1,2,3,4-四氢萘(THN)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CCC2=CC=CC=C2C1
InChI: InChI=1S/C10H12/c1-2-6-10-8-4-3-7-9(10)5-1/h1-2,5-6H,3-4,7-8H2
描述信息
同义名列表
41 个代谢物同义名
InChI=1\C10H12\c1-2-6-10-8-4-3-7-9(10)5-1\h1-2,5-6H,3-4,7-8H; Naphthalene, 1,2,3,4-tetrahydro-, C1-4-alkyl derivs.; (C4-C5) Alkyltetrahydronaphthalenes; EPA Pesticide Chemical Code 055901; .delta.(sup 5,7,9)-Naphthantriene; Naphthalene, 1,2,3,4-tetrahydro-; Naphthalene 1,2,3,4-tetrahydride; delta(sup 5,7,9)-naphthantriene; 1,2,3,4-Tetrahydronaphthalene; Tetrahydronaphthalene; Tetralina [Polish]; EINECS 204-340-2; EINECS 270-178-4; Caswell No. 842A; Tetralin solvent; Benzocyclohexane; NCGC00091744-01; NCIOpen2_000650; 456438_ALDRICH; 429325_ALDRICH; 522651_ALDRICH; WLN: L66 & TJ; 95462_FLUKA; CHEBI:35008; 68412-24-8; CCRIS 3564; Tetralene; NSC 77451; AI3-01257; Tetraline; Tetralina; HSDB 127; Tetranap; Tetralin; NSC77451; 119-64-2; Bacticin; C14114; c0986; Tetralin; 1,2,3,4-Tetrahydronaphthalene
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:35008
- PubChem: 8404
- ChEMBL: CHEMBL1575635
- CAS: 68412-24-8
- CAS: 119-64-2
- KEGG: C14114
- PubChem: 854350
- KNApSAcK: 35008
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 33090 - 葱白: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Inmaculada García-Romero, Juan Nogales, Eduardo Díaz, Eduardo Santero, Belén Floriano. Understanding the metabolism of the tetralin degrader Sphingopyxis granuli strain TFA through genome-scale metabolic modelling.
Scientific reports.
2020 05; 10(1):8651. doi:
10.1038/s41598-020-65258-9. [PMID: 32457330] - Huong T M Nguyen, Nga T Vo, Suong T M Huynh, Lien T M Do, Thammarat Aree, Santi Tip-Pyang, Cam-Tu D Phan, Nguyen T Trung, Phung K P Nguyen. A sesquiterpenoid tropolone and 1,2,3,4-tetrahydronaphthalene derivatives from Olax imbricata roots.
Fitoterapia.
2019 Jan; 132(?):1-6. doi:
10.1016/j.fitote.2018.11.007. [PMID: 30439445] - Shilpa Mohanty, Yashveer Gautam, Anil Kumar Maurya, Arvind S Negi, Om Prakash, Feroz Khan, Dnyaneshwar Umrao Bawankule. Indenes and tetralenes analogues attenuates lipopolysaccharide-induced inflammation: An in-vitro and in-vivo study.
Chemico-biological interactions.
2016 Feb; 245(?):12-9. doi:
10.1016/j.cbi.2015.12.005. [PMID: 26731479] - Guangbo Xie, Jin Tian, Katalin E Kövér, Attila Mándi, Tibor Kurtán. Structural and stereochemical studies of a tetralin norsesquiterpenoid from Ligularia kangtingensis.
Chirality.
2014 Sep; 26(9):574-9. doi:
10.1002/chir.22320. [PMID: 24830355] - Van Trinh Thi Thanh, Van Cuong Pham, Huong Doan Thi Mai, Marc Litaudon, Françoise Guéritte, Van Hung Nguyen, Van Minh Chau. Cytotoxic aryltetralin lignans from fruits of Cleistanthus indochinensis.
Planta medica.
2014 Jun; 80(8-9):695-702. doi:
10.1055/s-0034-1368505. [PMID: 24896244] - Ya-nan Yang, Zhao-zhen Liu, Zi-ming Feng, Jian-shuang Jiang, Pei-cheng Zhang. Lignans from the root of Rhodiola crenulata.
Journal of agricultural and food chemistry.
2012 Feb; 60(4):964-72. doi:
10.1021/jf204660c. [PMID: 22225005] - Michael A Brodney, David D Auperin, Stacey L Becker, Brian S Bronk, Tracy M Brown, Karen J Coffman, James E Finley, Carol D Hicks, Michael J Karmilowicz, Thomas A Lanz, Dane Liston, Xingrong Liu, Barbara-Anne Martin, Robert B Nelson, Charles E Nolan, Christine E Oborski, Christine P Parker, Karl E G Richter, Nikolay Pozdnyakov, Barbara G Sahagan, Joel B Schachter, Sharon A Sokolowski, Barbara Tate, Douglas E Wood, Kathleen M Wood, Jeffrey W Van Deusen, Lei Zhang. Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: discovery of PF-3084014.
Bioorganic & medicinal chemistry letters.
2011 May; 21(9):2637-40. doi:
10.1016/j.bmcl.2010.12.118. [PMID: 21269827] - . Toxicology and carcinogenesis studies of tetralin (CAS No. 119-64-2) in F344/N rats and B6C3F1 mice (inhalation studies).
National Toxicology Program technical report series.
2011 Apr; ?(561):1-198. doi:
. [PMID: 21685956] - Laura Ledesma García, Elena Rivas-Marín, Belén Floriano, Rita Bernhardt, Kerstin Maria Ewen, Francisca Reyes-Ramírez, Eduardo Santero. ThnY is a ferredoxin reductase-like iron-sulfur flavoprotein that has evolved to function as a regulator of tetralin biodegradation gene expression.
The Journal of biological chemistry.
2011 Jan; 286(3):1709-18. doi:
10.1074/jbc.m110.184648. [PMID: 21068394] - Yifei Zhong, Yingwei Wu, Ruijie Liu, Zhengzhe Li, Yibang Chen, Todd Evans, Peter Chuang, Bhaskar Das, John Cijiang He. Novel retinoic acid receptor alpha agonists for treatment of kidney disease.
PloS one.
2011; 6(11):e27945. doi:
10.1371/journal.pone.0027945. [PMID: 22125642] - Michael Stitz, Ian T Baldwin, Emmanuel Gaquerel. Diverting the flux of the JA pathway in Nicotiana attenuata compromises the plant's defense metabolism and fitness in nature and glasshouse.
PloS one.
2011; 6(10):e25925. doi:
10.1371/journal.pone.0025925. [PMID: 22022469] - Delfina A Ré, Carlos A Dezar, Raquel L Chan, Ian T Baldwin, Gustavo Bonaventure. Nicotiana attenuata NaHD20 plays a role in leaf ABA accumulation during water stress, benzylacetone emission from flowers, and the timing of bolting and flower transitions.
Journal of experimental botany.
2011 Jan; 62(1):155-66. doi:
10.1093/jxb/erq252. [PMID: 20713465] - Arjen VanDoorn, Mario Kallenbach, Alejandro A Borquez, Ian T Baldwin, Gustavo Bonaventure. Rapid modification of the insect elicitor N-linolenoyl-glutamate via a lipoxygenase-mediated mechanism on Nicotiana attenuata leaves.
BMC plant biology.
2010 Aug; 10(?):164. doi:
10.1186/1471-2229-10-164. [PMID: 20696061] - Siham Bezzi, Danny Kessler, Celia Diezel, Alexander Muck, Samir Anssour, Ian T Baldwin. Silencing NaTPI expression increases nectar germin, nectarins, and hydrogen peroxide levels and inhibits nectar removal from plants in nature.
Plant physiology.
2010 Apr; 152(4):2232-42. doi:
10.1104/pp.109.151753. [PMID: 20190094] - Rainer Schreiber, Inna Uliyakina, Patthara Kongsuphol, Richard Warth, Myriam Mirza, Joana R Martins, Karl Kunzelmann. Expression and function of epithelial anoctamins.
The Journal of biological chemistry.
2010 Mar; 285(10):7838-45. doi:
10.1074/jbc.m109.065367. [PMID: 20056604] - Simon Lucas, Ralf Heim, Christina Ries, Katarzyna E Schewe, Barbara Birk, Rolf W Hartmann. In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.
Journal of medicinal chemistry.
2008 Dec; 51(24):8077-87. doi:
10.1021/jm800888q. [PMID: 19049427] - Chandra Prakash, Kim A Johnson, Clinton M Schroeder, Michael J Potchoiba. Metabolism, distribution, and excretion of a next generation selective estrogen receptor modulator, lasofoxifene, in rats and monkeys.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Sep; 36(9):1753-69. doi:
10.1124/dmd.108.021808. [PMID: 18515329] - Chandra Prakash, Kim A Johnson, Mark J Gardner. Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1218-26. doi:
10.1124/dmd.108.020404. [PMID: 18372400] - Yukie Yanagiba, Yuki Ito, Osamu Yamanoshita, Shu-Yun Zhang, Gen Watanabe, Kazuyoshi Taya, Chun Mei Li, Yuko Inotsume, Michihiro Kamijima, Frank J Gonzalez, Tamie Nakajima. Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase.
Environmental health perspectives.
2008 Jun; 116(6):740-5. doi:
10.1289/ehp.10724. [PMID: 18560529] - Hans-Jürgen Federsel, Martin Hedberg, Fredrik R Qvarnström, Magnus P T Sjögren, Wei Tian. Construction of a chiral central nervous system (CNS)-active aminotetralin drug compound based on a synthesis strategy using multitasking properties of (S)-1-phenylethylamine.
Accounts of chemical research.
2007 Dec; 40(12):1377-84. doi:
10.1021/ar700102c. [PMID: 17668920] - Elinor Scott, Francisc Peter, Johan Sanders. Biomass in the manufacture of industrial products--the use of proteins and amino acids.
Applied microbiology and biotechnology.
2007 Jun; 75(4):751-62. doi:
10.1007/s00253-007-0932-x. [PMID: 17387469] - J Lowe, S Drozda, W Qian, M-C Peakman, J Liu, J Gibbs, J Harms, C Schmidt, K Fisher, C Strick, A Schmidt, M Vanase, L Lebel. A novel, non-substrate-based series of glycine type 1 transporter inhibitors derived from high-throughput screening.
Bioorganic & medicinal chemistry letters.
2007 Mar; 17(6):1675-8. doi:
10.1016/j.bmcl.2006.12.109. [PMID: 17257843] - Liping Song, Hui Li, Ulas Sunar, Juan Chen, Ian Corbin, Arjun G Yodh, Gang Zheng. Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment.
International journal of nanomedicine.
2007; 2(4):767-74. doi:
". [PMID: 18203443] - Desire D Tshala-Katumbay, Valerie S Palmer, Michael R Lasarev, Robert J Kayton, Mohammad I Sabri, Peter S Spencer. Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy.
Acta neuropathologica.
2006 Sep; 112(3):317-24. doi:
10.1007/s00401-006-0106-4. [PMID: 16874529] - Satish Chandra Puri, Asiya Nazir, Raman Chawla, Rajesh Arora, S Riyaz-Ul-Hasan, Touseef Amna, Bilal Ahmed, Vijeshwar Verma, Shikha Singh, Ravinder Sagar, Ashok Sharma, Raj Kumar, Rakesh Kumar Sharma, Ghulam Nabi Qazi. The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans.
Journal of biotechnology.
2006 Apr; 122(4):494-510. doi:
10.1016/j.jbiotec.2005.10.015. [PMID: 16375985] - Yoshio Furihata, Yoshiyuki Motokawa, Satoshi Murata, Sumiyoshi Kiguchi, Mamoru Kobayashi, Makoto Murakami, Masami Kojima, Toshinori Yamamoto. Cardiovascular effects of KUR-1246, a new tetrahydronaphthalen derivative beta2-adrenoceptor agonist and a selective uterine relaxant.
Arzneimittel-Forschung.
2006; 56(1):18-24. doi:
10.1055/s-0031-1296696. [PMID: 16478001] - Jens Heilmann, Sergei F Boulyga, Klaus G Heumann. Accurate determination of sulfur in gasoline and related fuel samples using isotope dilution ICP-MS with direct sample injection and microwave-assisted digestion.
Analytical and bioanalytical chemistry.
2004 Sep; 380(2):190-7. doi:
10.1007/s00216-004-2658-2. [PMID: 15232670] - Jin H Song, Andrew J Slot, Roby W J Ryan, Gregory M Ross. Dopamine-induced death of PC12 cells is prevented by a substituted tetrahydronaphthalene.
Neuropharmacology.
2004 Jun; 46(7):984-93. doi:
10.1016/j.neuropharm.2004.01.001. [PMID: 15081795] - S J Oh, H J Ha, D Y Chi, H K Lee. Serotonin receptor and transporter ligands - current status.
Current medicinal chemistry.
2001 Jul; 8(9):999-1034. doi:
10.2174/0929867013372599. [PMID: 11472239] - P SIMS. METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 1,4-EPOXY-1,4-DIHYDRONAPHTHALENE IN RATS.
The Biochemical journal.
1965 Jun; 95(?):608-11. doi:
10.1042/bj0950608. [PMID: 14342493]
