WLN: RSR (BioDeep_00000864416)

   


代谢物信息卡片


InChI=1\C12H10S\c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12\h1-10

化学式: C12H10S (186.050318)
中文名称: 二苯基硫醚, 苯硫醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)SC2=CC=CC=C2
InChI: InChI=1S/C12H10S/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10H

描述信息

同义名列表

33 个代谢物同义名

InChI=1\C12H10S\c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12\h1-10; 1,1-sulfanediyldibenzene; (Phenylsulfanyl)benzene; Benzene, 1,1-thiobis-; phenylsulfanylbenzene; 1,1-Thiobis(benzene); Diphenyl monosulfide; Diphenylthiamethane; (phenylthio)benzene; Diphenyl thioether; Phenylthiobenzene; Sulfide, diphenyl; Diphenylmercaptan; Diphenyl sulphide; 1,1-thiodibenzene; SULFIDE,DIPHENYL; EINECS 205-371-4; Diphenyl sulfide; Diphenylsulphide; P35316_ALDRICH; Phenyl sulfide; Diphenylsulfid; PHENYLSULFIDE; 36720_RIEDEL; ZINC01679972; CHEBI:38959; 43320_FLUKA; AI3-10564; WLN: RSR; 139-66-2; NSC 4568; NSC4568; Diphenyl sulfide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yan Zhang, Futao Liu, Hao Xiao, Xinyue Yao, Genxun Li, Seok Rye Choi, Karl Ploessl, Zhihao Zha, Lin Zhu, Hank F Kung. Fluorine-18 labeled diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain. Nuclear medicine and biology. 2018 11; 66(?):1-9. doi: 10.1016/j.nucmedbio.2018.06.008. [PMID: 30096380]
  • Fabienne Gourand, Nahid Amini, Zhisheng Jia, Sharon Stone-Elander, Denis Guilloteau, Louisa Barré, Christer Halldin. [11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET). PloS one. 2015; 10(9):e0137160. doi: 10.1371/journal.pone.0137160. [PMID: 26367261]
  • Nashwa Jarkas. Fluorinated diaryl sulfides. Current topics in medicinal chemistry. 2013; 13(8):936-43. doi: 10.2174/1568026611313080006. [PMID: 23590166]
  • Xuesheng Zhang, Fu Liu, Binyuan Chen, Ying Li, Zunyao Wang. Acute and subacute oral toxicity of polychlorinated diphenyl sulfides in mice: determining LD50 and assessing the status of hepatic oxidative stress. Environmental toxicology and chemistry. 2012 Jul; 31(7):1485-93. doi: 10.1002/etc.1861. [PMID: 22549922]
  • Nachwa Jarkas, Ronald J Voll, Larry Williams, John R Votaw, Mike Owens, Mark M Goodman. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands. Journal of medicinal chemistry. 2008 Jan; 51(2):271-81. doi: 10.1021/jm0707929. [PMID: 18085744]
  • Johnny Vercouillie, Sylvie Mavel, Laurent Galineau, Tiziana Ragusa, Robert Innis, Michael Kassiou, Sylvie Chalon, Frédéric Dollé, Jean-Claude Besnard, Denis Guilloteau, Patrick Emond. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands. Bioorganic & medicinal chemistry letters. 2006 Mar; 16(5):1297-300. doi: 10.1016/j.bmcl.2005.11.066. [PMID: 16337793]
  • D Guilloteau, S Chalon. PET and SPECT exploration of central monoaminergic transporters for the development of new drugs and treatments in brain disorders. Current pharmaceutical design. 2005; 11(25):3237-45. doi: 10.2174/138161205774424744. [PMID: 16250852]
  • Ivo P Nnane, Lyaquat A Damani. Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole. Biomedical chromatography : BMC. 2005 Jan; 19(1):87-98. doi: 10.1002/bmc.421. [PMID: 15470701]
  • Aysen Muezzinoglu. A study of volatile organic sulfur emissions causing urban odors. Chemosphere. 2003 Apr; 51(4):245-52. doi: 10.1016/s0045-6535(02)00821-4. [PMID: 12604076]
  • Sylvie Chalon, Jari Tarkiainen, Lucette Garreau, Hakan Hall, Patrick Emond, Johnny Vercouillie, Lars Farde, Philippe Dasse, Katarina Varnas, Jean-Claude Besnard, Christer Halldin, Denis Guilloteau. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity. The Journal of pharmacology and experimental therapeutics. 2003 Jan; 304(1):81-7. doi: 10.1124/jpet.102.042226. [PMID: 12490578]
  • Shunichi Oya, Seok Rye Choi, Heinz Coenen, Hank F Kung. New PET imaging agent for the serotonin transporter: [(18)F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine). Journal of medicinal chemistry. 2002 Oct; 45(21):4716-23. doi: 10.1021/jm020167y. [PMID: 12361398]
  • Julia Wellsow, Karl-Artur Kovar, Hans-Jürgen Machulla. Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. Positron Emission Tomography. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2002 Sep; 5(3):245-57. doi: . [PMID: 12553893]
  • Patrick Emond, Johnny Vercouillie, Robert Innis, Sylvie Chalon, Sylvie Mavel, Yves Frangin, Christer Halldin, Jean-Claude Besnard, Denis Guilloteau. Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation. Journal of medicinal chemistry. 2002 Mar; 45(6):1253-8. doi: 10.1021/jm010939a. [PMID: 11881994]