Redskin (BioDeep_00000862716)
Main id: BioDeep_00000003215
代谢物信息卡片
Allyl isothiocyanate, stabilized [UN1545] [Poison]
化学式: C4H5NS (99.0143)
中文名称: 天然芥菜籽油, 异硫氰酸烯丙酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=CCN=C=S
InChI: InChI=1S/C4H5NS/c1-2-3-5-4-6/h2H,1,3H2
描述信息
D000074385 - Food Ingredients > D005503 - Food Additives > D005520 - Food Preservatives
同义名列表
83 个代谢物同义名
Allyl isothiocyanate, stabilized [UN1545] [Poison]; 4-04-00-01081 (Beilstein Handbook Reference); Potassium, (1-isothiocyanato-2-propenyl)-; Allyl isothiocyanate, non-perfume grade; InChI=1\C4H5NS\c1-2-3-5-4-6\h2H,1,3H; EPA Pesticide Chemical Code 004901; Mustard oil, volatile, synthetic; Isothiocyanic acid, allyl ester; Isothiocyanate dallyle [French]; ISOTHIOCYANIC ACID,ALLYL ESTER; Potassium allyl isothiocyanate; Allyl isothiocyanate (natural); 1-Propene, 3-isothiocyanato-; Isothiocyansaeureallylester; Allyl isothiocyanate [USAN]; Allyl isothiocyanate (USP); 3-Isothiocyanato-1-propene; 3-Isothiocyanatoprop-1-ene; Allylisothiokyanat [Czech]; Oil of mustard, artificial; Propene, 3-isothiocyanato-; 2-Propenyl isothiocyanate; Artificial oil of mustard; allylimino-thioxo-methane; Oil of mustard BPC 1949; Volatile oil OF mustard; Artificial mustard oil; Oleum sinapis volatile; Allyl isosulphocyanate; Isothiocyanate dallyle; Allyl isosulfocyanate; Allylsenfoel [German]; Synthetic mustard oil; Mustard oil, volatile; ALLYL ISOTHIOCYANATE; Volatile mustard oil; Allyl thioisocyanate; Mustard oil (VAN); Allyl mustard oil; Senf oel [German]; FEMA Number 2034; EINECS 200-309-2; Allyl sevenolum; NCGC00091743-01; Caswell no. 027; Mustardseed Oil; W203408_ALDRICH; 377430_ALDRICH; Oil OF mustard; Allylsevenolum; Oleum sinapis; Allyspol 75EC; FEMA no. 2034; ZINC01687017; Allylsenfoel; 36682_RIEDEL; Allylsenevol; 107231-30-1; Mustard oil; 06019_FLUKA; BRN 0773748; WLN: SCN2U1; NCI-C50464; 50888-64-7; 50978-48-8; 58391-87-0; Carbospol; AI3-15283; CCRIS 20; Senf oel; NSC 5572; Allyspol; HSDB 617; NSC5572; LS-1387; LS-3207; Redskin; 57-06-7; Senfoel; D02818; UN1545; AITC; Allyl isothiocyanate
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:73224
- KEGG: C19317
- PubChem: 5971
- ChEMBL: CHEMBL233248
- CAS: 8007-40-7
- CAS: 57-06-7
- PubChem: 124489989
- PDB-CCD: UL9
- KNApSAcK: 73224
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
16 个相关的物种来源信息
- 126270 - Alliaria petiolata: 10.1002/JLAC.18440520103
- 130426 - Allium chinense: 10.1186/1756-3305-7-184
- 457768 - Alyssum desertorum: 10.1016/S0021-9673(00)91513-9
- 1112304 - Alyssum turkestanicum: 10.1016/S0021-9673(00)91513-9
- 3704 - Armoracia rusticana: 10.1002/JLAC.18430470205
- 52824 - Brassica carinata: 10.1016/0031-9422(88)83085-1
- 3707 - Brassica juncea:
- 3708 - Brassica napus:
- 3710 - Brassica nigra:
- 3712 - Brassica oleracea:
- 89411 - Descurainia sophia: 10.1016/S0021-9673(00)91513-9
- 75806 - Eutrema japonicum:
- 226051 - Lobularia maritima: 10.1016/S0021-9673(00)91513-9
- 3728 - Sinapis alba: 10.1021/JF8022244
- 33090 - 芥子: -
- 33090 - 葶苈子: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rupinder Kaur Sodhi, Hemant Kumar, Raghunath Singh, Yashika Bansal, Yuvraj Singh, Kanthi Kiran Kondepudi, Mahendra Bishnoi, Anurag Kuhad. Allyl isothiocyanate, a TRPA1 agonist, protects against olanzapine-induced hypothalamic and hepatic metabolic aberrations in female mice.
Biochemical pharmacology.
2024 Apr; 222(?):116074. doi:
10.1016/j.bcp.2024.116074. [PMID: 38395265] - Houjun Tian, Ruibin Xu, Heng Li, Shuo Lin, Yixin Chen, Yong Chen, Guang Yang, Hui Wei. Prolonged Exposure to Plant Volatiles does not Significantly Affect Pban Expression and Mating Behavior in Diamondback Moth [Plutella Xylostella (Lepidoptera: Plutellidae)].
Journal of chemical ecology.
2024 Feb; 50(1-2):18-29. doi:
10.1007/s10886-023-01462-x. [PMID: 38051449] - Juan Diego Barea-Ramos, María José Rodríguez, Patricia Calvo, Félix Melendez, Jesús Lozano, Daniel Martín-Vertedor. Inhibition of Botrytis cinerea in tomatoes by allyl-isothiocyanate release from black mustard (Brassica nigra) seeds and detection by E-nose.
Food chemistry.
2024 Jan; 432(?):137222. doi:
10.1016/j.foodchem.2023.137222. [PMID: 37625300] - Yingbin Li, Daqing Lu, Yan Xia, Xinjing Xu, Huichuan Huang, Xinyue Mei, Min Yang, Jianqiang Li, Shusheng Zhu, Yixiang Liu, Zhiping Zhang. Effects of allyl isothiocyanate fumigation on medicinal plant root knot disease control, plant survival, and the soil bacterial community.
BMC microbiology.
2023 09; 23(1):278. doi:
10.1186/s12866-023-02992-w. [PMID: 37775764] - Wantong Jia, Huilin Yu, Jinyu Fan, Jiyue Zhang, Hongyu Pan, Xianghui Zhang. The histidine kinases regulate allyl-isothiocyanate sensitivity in Cochliobolus heterostrophus.
Pest management science.
2023 Sep; ?(?):. doi:
10.1002/ps.7777. [PMID: 37743431] - Sándor Koczor, Miklós Tóth. Field attraction of Eurydema ornata (Hemiptera: Pentatomidae) to allyl isothiocyanate.
Scientific reports.
2023 Jul; 13(1):11063. doi:
10.1038/s41598-023-37705-w. [PMID: 37422493] - Yi Zhang, Wensheng Fang, Dongdong Yan, Yutong Ji, Xinhua Chen, Anmin Guo, Zhaoxin Song, Yuan Li, Aocheng Cao, Qiuxia Wang. Comparison of drip-irrigated or injected allyl isothiocyanate against key soil-borne pathogens and weeds.
Pest management science.
2023 May; ?(?):. doi:
10.1002/ps.7590. [PMID: 37256601] - Linlin Jiang, Yue Li, Weilin Shi, Wei Chen, Zhiqing Ma, Juntao Feng, Ahmed S Hashem, Hua Wu. Cloning and expression of the mitochondrial cytochrome c oxidase subunit II gene in Sitophilus zeamais and interaction mechanism with allyl isothiocyanate.
Pesticide biochemistry and physiology.
2023 May; 192(?):105392. doi:
10.1016/j.pestbp.2023.105392. [PMID: 37105630] - Lina B Flor-Weiler, Robert W Behle, Mark A Berhow, Susan P McCormick, Steven F Vaughn, Ephantus J Muturi, William T Hay. Bioactivity of brassica seed meals and its compounds as ecofriendly larvicides against mosquitoes.
Scientific reports.
2023 Mar; 13(1):3936. doi:
10.1038/s41598-023-30563-6. [PMID: 36894606] - Yi Zhang, Jie Liu, Aocheng Cao, Xiujun Tang, Xinhua Chen, Wensheng Fang, Yuan Li, Dongdong Yan, Qiuxia Wang. Effects of fertilizers and soil amendments on the degradation rate of allyl isothiocyanate in two typical soils of China.
Pest management science.
2022 Dec; 78(12):5191-5202. doi:
10.1002/ps.7138. [PMID: 36087020] - Kung-Wen Lu, Tai-Jung Lu, Fu-Shin Chueh, Kuang-Chi Lai, Te-Chun Hsia, Shu-Fen Peng, Ching-Chang Cheng, Yu-Cheng Chou, Fei-Ting Hsu. Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model.
International journal of molecular sciences.
2022 Sep; 23(18):. doi:
10.3390/ijms231810411. [PMID: 36142326] - Monika Okulicz, Iwona Hertig, Ewelina Król, Tomasz Szkudelski. Effects of Allyl Isothiocyanate on Oxidative and Inflammatory Stress in Type 2 Diabetic Rats.
Molecules (Basel, Switzerland).
2022 Aug; 27(17):. doi:
10.3390/molecules27175568. [PMID: 36080332] - Hiu-Lok Ngan, Tao Wang, Yi Ru, Yanyan Chen, Charlie Li, Zongwei Cai. Simultaneous analysis of derivatized allyl isothiocyanate together with its phase II metabolites by ultra-high-performance liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2022 Apr; 36(7):e9257. doi:
10.1002/rcm.9257. [PMID: 35037320] - Liwen Jiang, Yong Li, Chaoyi Xue, Zhiyong He, Zhaojun Wang, Fang Qin, Jie Chen, Maomao Zeng. The inhibitory effects of yellow mustard (Brassica juncea) and its characteristic pungent ingredient allyl isothiocyanate (AITC) on PhIP formation: Focused on the inhibitory pathways of AITC.
Food chemistry.
2022 Mar; 373(Pt A):131398. doi:
10.1016/j.foodchem.2021.131398. [PMID: 34710679] - Shaimaa Waz, Asmaa I Matouk. Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity.
Toxicology mechanisms and methods.
2022 Mar; 32(3):194-203. doi:
10.1080/15376516.2021.1992064. [PMID: 34635025] - S Yadav, P-Y Teng, A K Singh, J Choi, W K Kim. Influence of Brassica spp. rapeseed and canola meal, and supplementation of bioactive compound (AITC) on growth performance, intestinal-permeability, oocyst shedding, lesion score, histomorphology, and gene expression of broilers challenged with E. maxima.
Poultry science.
2022 Feb; 101(2):101583. doi:
10.1016/j.psj.2021.101583. [PMID: 34915210] - Monika Okulicz, Iwona Hertig, Tomasz Szkudelski. Differentiated Effects of Allyl Isothiocyanate in Diabetic Rats: From Toxic to Beneficial Action.
Toxins.
2021 12; 14(1):. doi:
10.3390/toxins14010003. [PMID: 35050980] - Zhe Zhang, Jianhao Pan, Tao Zhu, Nathalie Malewicz, Kaihe Ye, Jianhui Rong, Yong Luo, Yongli Situ, Alexei Verkhratsky, Yong Wang, Jianhao Zhao, Dan Tang, Hong Nie. Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch.
The Journal of pharmacy and pharmacology.
2021 Dec; 73(12):1617-1629. doi:
10.1093/jpp/rgab145. [PMID: 34718677] - Cemal Orhan, Hasan Gencoglu, Mehmet Tuzcu, Nurhan Sahin, Ibrahim Hanifi Ozercan, Abhijeet Ashok Morde, Muralidhara Padigaru, Kazim Sahin. Allyl isothiocyanate attenuates LED light-induced retinal damage in rats: exploration for the potential molecular mechanisms.
Cutaneous and ocular toxicology.
2021 Dec; 40(4):376-386. doi:
10.1080/15569527.2021.1978478. [PMID: 34493133] - Wen-Tao Zhu, Chen-Hui Li, Ting-Ting Dai, Fu-Lin Tao, Meng-Wen Wang, Chong-Yang Wang, Zhi-Li Han, Nian-Xia Sun, Ya-Nan Zhao, Dian-Lei Wang. Effects of allyl isothiocyanate on the expression, function, and its mechanism of ABCA1 and ABCG1 in pulmonary of COPD rats.
International immunopharmacology.
2021 Dec; 101(Pt B):108373. doi:
10.1016/j.intimp.2021.108373. [PMID: 34802946] - Hyun-Jong Song, Kang-Mo Ku. Optimization of allyl isothiocyanate sanitizing concentration for inactivation of Salmonella Typhimurium on lettuce based on its phenotypic and metabolome changes.
Food chemistry.
2021 Dec; 364(?):130438. doi:
10.1016/j.foodchem.2021.130438. [PMID: 34186479] - Haijiao Liu, Jiaqing Wu, Yingwei Su, Yingbin Li, Denghong Zuo, Hongbin Liu, Yixiang Liu, Xinyue Mei, Huichuan Huang, Min Yang, Shusheng Zhu. Allyl Isothiocyanate in the Volatiles of Brassica juncea Inhibits the Growth of Root Rot Pathogens of Panax notoginseng by Inducing the Accumulation of ROS.
Journal of agricultural and food chemistry.
2021 Nov; 69(46):13713-13723. doi:
10.1021/acs.jafc.1c05225. [PMID: 34780155] - Phyllis Chan, Han Ting Ding, Bianca M Liederer, Jialin Mao, Paula Belloni, Liuxi Chen, Simon S Gao, Victory Joseph, Xiaoying Yang, Joseph S Lin, Mayur S Mitra, Wendy S Putnam, Angelica Quartino, Rebecca N Bauer, Lin Pan. Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor.
Clinical and translational science.
2021 09; 14(5):1945-1954. doi:
10.1111/cts.13049. [PMID: 34058071] - Michael G Alvarado, Pratish Thakore, Scott Earley. Transient Receptor Potential Channel Ankyrin 1: A Unique Regulator of Vascular Function.
Cells.
2021 05; 10(5):. doi:
10.3390/cells10051167. [PMID: 34064835] - Hirosato Kanda, Yanjing Yang, Shaoqi Duan, Yoko Kogure, Shenglan Wang, Emiko Iwaoka, Miku Ishikawa, Saki Takeda, Hidemi Sonoda, Kyoka Mizuta, Shunji Aoki, Satoshi Yamamoto, Koichi Noguchi, Yi Dai. Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation.
International journal of molecular sciences.
2021 Mar; 22(7):. doi:
10.3390/ijms22073614. [PMID: 33807167] - Min Zhang, Dan Zhang, Jingjing Ren, Shi Pu, Hua Wu, Zhiqing Ma. Target verification of allyl isothiocyanate on the core subunits of cytochrome c oxidase in Sitophilus zeamais by RNAi.
Pest management science.
2021 Mar; 77(3):1292-1302. doi:
10.1002/ps.6142. [PMID: 33063911] - Pei-Ying Chang, Fuu-Jen Tsai, Da-Tian Bau, Yuan-Man Hsu, Jai-Sing Yang, Ming-Gene Tu, Shang-Lun Chiang. Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells.
Journal of the Formosan Medical Association = Taiwan yi zhi.
2021 Jan; 120(1 Pt 2):515-523. doi:
10.1016/j.jfma.2020.06.025. [PMID: 32624316] - Kazuki Hashimoto, Kimihito Tashima, Taku Imai, Kenjiro Matsumoto, Syunji Horie. The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia.
Journal of pharmacological sciences.
2021 Jan; 145(1):122-129. doi:
10.1016/j.jphs.2020.10.006. [PMID: 33357770] - Naoko Masumoto, Yuzo Nishizaki, Kaori Nakajima, Naoki Sugimoto, Kyoko Sato. [Determination of Allyl Isothiocyanate in Mustard and Horseradish Extracts by Single Reference GC and HPLC Based on Relative Molar Sensitivities].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan.
2021; 62(3):73-78. doi:
10.3358/shokueishi.62.73. [PMID: 34219099] - Hoai T T Tran, Rebecca Stetter, Corinna Herz, Jenny Spöttel, Mareike Krell, Franziska S Hanschen, Monika Schreiner, Sascha Rohn, Maik Behrens, Evelyn Lamy. Allyl Isothiocyanate: A TAS2R38 Receptor-Dependent Immune Modulator at the Interface Between Personalized Medicine and Nutrition.
Frontiers in immunology.
2021; 12(?):669005. doi:
10.3389/fimmu.2021.669005. [PMID: 33968075] - Jonas Vandicke, Katrien De Visschere, Sofie Deconinck, Diederik Leenknecht, Pieter Vermeir, Kris Audenaert, Geert Haesaert. Uncovering the biofumigant capacity of allyl isothiocyanate from several Brassicaceae crops against Fusarium pathogens in maize.
Journal of the science of food and agriculture.
2020 Dec; 100(15):5476-5486. doi:
10.1002/jsfa.10599. [PMID: 32564371] - Sabrina Eib, Désirée Janet Schneider, Oliver Hensel, Ingrid Seuß-Baum. Relationship between mustard pungency and allyl-isothiocyanate content: A comparison of sensory and chemical evaluations.
Journal of food science.
2020 Sep; 85(9):2728-2736. doi:
10.1111/1750-3841.15383. [PMID: 32844444] - Carla Guijarro-Real, Jaime Prohens, Adrián Rodríguez-Burruezo, Ana Fita. Consumers acceptance and volatile profile of wall rocket (Diplotaxis erucoides).
Food research international (Ottawa, Ont.).
2020 06; 132(?):109008. doi:
10.1016/j.foodres.2020.109008. [PMID: 32331664] - Wenxiu Ye, Eigo Ando, Mohammad Saidur Rhaman, Md Tahjib-Ul-Arif, Eiji Okuma, Yoshimasa Nakamura, Toshinori Kinoshita, Yoshiyuki Murata. Inhibition of light-induced stomatal opening by allyl isothiocyanate does not require guard cell cytosolic Ca2+ signaling.
Journal of experimental botany.
2020 05; 71(10):2922-2932. doi:
10.1093/jxb/eraa073. [PMID: 32103265] - Rajakumar Thangarasu, Pugalendhi Pachaiappan, Thilagavathi Subbaiyan. Anti-Estrogenic and Anti-Cell Proliferative Effect of Allyl Isothiocyanate in Chemoprevention of Chemically Induced Mammary Carcinogenesis in Rats.
Pathology oncology research : POR.
2020 Apr; 26(2):913-925. doi:
10.1007/s12253-019-00638-9. [PMID: 30895454] - Jie Liu, Xianli Wang, Wensheng Fang, Dongdong Yan, Dawei Han, Bin Huang, Yi Zhang, Yuan Li, Canbin Ouyang, Aocheng Cao, Qiuxia Wang. Soil properties, presence of microorganisms, application dose, soil moisture and temperature influence the degradation rate of Allyl isothiocyanate in soil.
Chemosphere.
2020 Apr; 244(?):125540. doi:
10.1016/j.chemosphere.2019.125540. [PMID: 32050338] - Nur Alim Bahmid, Laurens Pepping, Matthijs Dekker, Vincenzo Fogliano, Jenneke Heising. Using particle size and fat content to control the release of Allyl isothiocyanate from ground mustard seeds for its application in antimicrobial packaging.
Food chemistry.
2020 Mar; 308(?):125573. doi:
10.1016/j.foodchem.2019.125573. [PMID: 31639598] - Melina Mitsiogianni, Theodora Mantso, Dimitrios T Trafalis, H P Vasantha Rupasinghe, Vasilis Zoumpourlis, Rodrigo Franco, Sotiris Botaitis, Aglaia Pappa, Mihalis I Panayiotidis. Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.
European journal of nutrition.
2020 Mar; 59(2):557-569. doi:
10.1007/s00394-019-01925-6. [PMID: 30762097] - Jiahong Zhu, Zongjie Ren, Bin Huang, Aocheng Cao, Qiuxia Wang, Dongdong Yan, Canbin Ouyang, Jiajia Wu, Yuan Li. Effects of Fumigation with Allyl Isothiocyanate on Soil Microbial Diversity and Community Structure of Tomato.
Journal of agricultural and food chemistry.
2020 Feb; 68(5):1226-1236. doi:
10.1021/acs.jafc.9b07292. [PMID: 31922739] - M Piochi, G Cabrino, G Morini, L Torri. Individual differences in the perception of orthonasal irritation induced by food.
Appetite.
2020 01; 144(?):104460. doi:
10.1016/j.appet.2019.104460. [PMID: 31536745] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Jialin Yu, Gary E Vallad, Nathan S Boyd. Evaluation of Allyl Isothiocyanate as a Soil Fumigant for Tomato (Lycopersicon esculentum Mill.) Production.
Plant disease.
2019 Nov; 103(11):2764-2770. doi:
10.1094/pdis-11-18-2013-re. [PMID: 31490090] - Chun-Xiao Li, Jian-Guo Gao, Xing-Yong Wan, Yi Chen, Cheng-Fu Xu, Ze-Min Feng, Hang Zeng, Yi-Ming Lin, Han Ma, Ping Xu, Chao-Hui Yu, You-Ming Li. Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways.
World journal of gastroenterology.
2019 Sep; 25(34):5120-5133. doi:
10.3748/wjg.v25.i34.5120. [PMID: 31558861] - Qixia Shen, Wenyu Xiang, Sen Ye, Xin Lei, Lefeng Wang, Sha Jia, Xue Shao, Chunhua Weng, Xiujin Shen, Yucheng Wang, Shi Feng, Lihui Qu, Cuili Wang, Jianghua Chen, Ping Zhang, Hong Jiang. Plasma metabolite biomarkers related to secondary hyperparathyroidism and parathyroid hormone.
Journal of cellular biochemistry.
2019 09; 120(9):15766-15775. doi:
10.1002/jcb.28846. [PMID: 31069832] - Luisa Ugolini, Eleonora Pagnotta, Roberto Matteo, Lorena Malaguti, Alessandra Di Francesco, Luca Lazzeri. Brassica meal-derived allyl-isothiocyanate postharvest application: influence on strawberry nutraceutical and biochemical parameters.
Journal of the science of food and agriculture.
2019 Jul; 99(9):4235-4241. doi:
10.1002/jsfa.9654. [PMID: 30801703] - Nurhan Sahin, Cemal Orhan, Fusun Erten, Mehmet Tuzcu, Patrick B Defo Deeh, Ibrahim H Ozercan, Vijaya Juturu, Sahin Kazim. Effects of allyl isothiocyanate on insulin resistance, oxidative stress status, and transcription factors in high-fat diet/streptozotocin-induced type 2 diabetes mellitus in rats.
Journal of biochemical and molecular toxicology.
2019 Jul; 33(7):e22328. doi:
10.1002/jbt.22328. [PMID: 30927557] - Likun Wang, Mark Mazzola. Effect of Soil Physical Conditions on Emission of Allyl Isothiocyanate and Subsequent Microbial Inhibition in Response to Brassicaceae Seed Meal Amendment.
Plant disease.
2019 May; 103(5):846-852. doi:
10.1094/pdis-08-18-1389-re. [PMID: 30856078] - Ivica Blažević, Azra Đulović, Ana Maravić, Vedrana Čikeš Čulić, Sabine Montaut, Patrick Rollin. Antimicrobial and Cytotoxic Activities of Lepidium latifolium L. Hydrodistillate, Extract and Its Major Sulfur Volatile Allyl Isothiocyanate.
Chemistry & biodiversity.
2019 Apr; 16(4):e1800661. doi:
10.1002/cbdv.201800661. [PMID: 30714673] - Raquel Torrijos, Tiago M Nazareth, Júlia Pérez, Jordi Mañes, Giuseppe Meca. Development of a Bioactive Sauce Based on Oriental Mustard Flour with Antifungal Properties for Pita Bread Shelf Life Improvement.
Molecules (Basel, Switzerland).
2019 Mar; 24(6):. doi:
10.3390/molecules24061019. [PMID: 30875724] - Juliana S Baggio, Manuel Chamorro, Leandro G Cordova, Joseph W Noling, Gary E Vallad, Natalia A Peres. Effect of Formulations of Allyl Isothiocyanate on Survival of Macrophomina phaseolina from Strawberry.
Plant disease.
2018 11; 102(11):2212-2219. doi:
10.1094/pdis-01-18-0172-re. [PMID: 30222054] - János Urbancsok, Atle M Bones, Ralph Kissen. Arabidopsis mutants impaired in glutathione biosynthesis exhibit higher sensitivity towards the glucosinolate hydrolysis product allyl-isothiocyanate.
Scientific reports.
2018 06; 8(1):9809. doi:
10.1038/s41598-018-28099-1. [PMID: 29955088] - Zsolt Szűcs, Tamás Plaszkó, Zoltán Cziáky, Attila Kiss-Szikszai, Tamás Emri, Regina Bertóti, László Tamás Sinka, Gábor Vasas, Sándor Gonda. Endophytic fungi from the roots of horseradish (Armoracia rusticana) and their interactions with the defensive metabolites of the glucosinolate - myrosinase - isothiocyanate system.
BMC plant biology.
2018 May; 18(1):85. doi:
10.1186/s12870-018-1295-4. [PMID: 29743024] - Chia-Wen Lo, Chih-Sheng Chen, Ying-Chi Chen, Yu-An Hsu, Chi-Chun Huang, Ching-Yao Chang, Chao-Jen Lin, Cheng-Wen Lin, Hui-Ju Lin, Fu-Tong Liu, Lei Wan. Allyl Isothiocyanate Ameliorates Obesity by Inhibiting Galectin-12.
Molecular nutrition & food research.
2018 03; 62(6):e1700616. doi:
10.1002/mnfr.201700616. [PMID: 29345776] - Sudarsan Mukhopadhyay, Kimberly Sokorai, Dike O Ukuku, Tony Jin, Xuetong Fan, Modesto Olanya, Vijay Juneja. Inactivation of Salmonella in grape tomato stem scars by organic acid wash and chitosan-allyl isothiocyanate coating.
International journal of food microbiology.
2018 Feb; 266(?):234-240. doi:
10.1016/j.ijfoodmicro.2017.12.018. [PMID: 29272723] - Thangarasu Rajakumar, Pachaiappan Pugalendhi, Rajendran Jayaganesh, Dhanabalan Ananthakrishnan, Krishnaswamy Gunasekaran. Effect of allyl isothiocyanate on NF-κB signaling in 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea-induced mammary carcinogenesis.
Breast cancer (Tokyo, Japan).
2018 Jan; 25(1):50-59. doi:
10.1007/s12282-017-0783-y. [PMID: 28501931] - Thangarasu Rajakumar, Pachaiappan Pugalendhi, Subbaiyan Thilagavathi, Dhanabalan Ananthakrishnan, Krishnaswamy Gunasekaran. Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis.
Molecular and cellular biochemistry.
2018 Jan; 437(1-2):1-12. doi:
10.1007/s11010-017-3091-0. [PMID: 28585088] - Yan Xu, Ji Jia, Chuangbo Xie, Youping Wu, Weifeng Tu. Transient Receptor Potential Ankyrin 1 and Substance P Mediate the Development of Gastric Mucosal Lesions in a Water Immersion Restraint Stress Rat Model.
Digestion.
2018; 97(3):228-239. doi:
10.1159/000484980. [PMID: 29428952] - János Urbancsok, Atle M Bones, Ralph Kissen. Glucosinolate-Derived Isothiocyanates Inhibit Arabidopsis Growth and the Potency Depends on Their Side Chain Structure.
International journal of molecular sciences.
2017 Nov; 18(11):. doi:
10.3390/ijms18112372. [PMID: 29117115] - Mirjam Langeveld, Chong Yew Tan, Maarten R Soeters, Samuel Virtue, Laura Pe Watson, Peter R Murgatroyd, Graeme K Ambler, Santiago Vidal-Puig, Krishna V Chatterjee, Antonio Vidal-Puig. No metabolic effects of mustard allyl-isothiocyanate compared with placebo in men.
The American journal of clinical nutrition.
2017 Nov; 106(5):1197-1205. doi:
10.3945/ajcn.116.148395. [PMID: 29070564] - Syuhei Nakao, Miyuki Mabuchi, Shenglan Wang, Yoko Kogure, Tadashi Shimizu, Koichi Noguchi, Akito Tanaka, Yi Dai. Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.
Bioorganic & medicinal chemistry letters.
2017 07; 27(14):3167-3172. doi:
10.1016/j.bmcl.2017.05.025. [PMID: 28576617] - Lalita Subedi, Ramu Venkatesan, Sun Yeou Kim. Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling.
International journal of molecular sciences.
2017 Jul; 18(7):. doi:
10.3390/ijms18071423. [PMID: 28671636] - Yeon Jeong Jang, Bongkyun Park, Hee-Weon Lee, Hye Jin Park, Hyun Jung Koo, Byung Oh Kim, Eun-Hwa Sohn, Sung Hee Um, Suhkneung Pyo. Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.
Chemico-biological interactions.
2017 Jun; 272(?):28-36. doi:
10.1016/j.cbi.2017.05.006. [PMID: 28483571] - Cai-Hua Shi, Jing-Rong Hu, Wen Xie, Yu-Ting Yang, Shao-Li Wang, You-Jun Zhang. Control of Bradysia odoriphaga (Diptera: Sciaridae) With Allyl Isothiocyanate Under Field and Greenhouse Conditions.
Journal of economic entomology.
2017 06; 110(3):1127-1132. doi:
10.1093/jee/tow303. [PMID: 28334285] - Yuko Shimamura, Misako Iio, Tomoko Urahira, Shuichi Masuda. Inhibitory effects of Japanese horseradish (Wasabia japonica) on the formation and genotoxicity of a potent carcinogen, acrylamide.
Journal of the science of food and agriculture.
2017 Jun; 97(8):2419-2425. doi:
10.1002/jsfa.8055. [PMID: 27670634] - Shuichi Masuda, Hideki Masuda, Yuko Shimamura, Chitose Sugiyama, Fumiyo Takabayashi. Improvement Effects of Wasabi (Wasabiajaponica) Leaves and Allyl Isothiocyanate on Stomach Lesions of Mongolian Gerbils Infected with Helicobacter pylori.
Natural product communications.
2017 Apr; 12(4):595-598. doi:
". [PMID: 30520603] - Wenda Wu, Hui-Ren Zhou, James J Pestka. Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin).
Archives of toxicology.
2017 Jan; 91(1):495-507. doi:
10.1007/s00204-016-1687-x. [PMID: 26979077] - Wenda Wu, Hui-Ren Zhou, Steven J Bursian, Jane E Link, James J Pestka. Calcium-Sensing Receptor and Transient Receptor Ankyrin-1 Mediate Emesis Induction by Deoxynivalenol (Vomitoxin).
Toxicological sciences : an official journal of the Society of Toxicology.
2017 01; 155(1):32-42. doi:
10.1093/toxsci/kfw191. [PMID: 27667315] - Zhongyong Jiang, Xi Liu, Kai Chang, Xia Liu, Jie Xiong. Allyl Isothiocyanate Inhibits the Proliferation of Renal Carcinoma Cell Line GRC-1 by Inducing an Imbalance Between Bcl2 and Bax.
Medical science monitor : international medical journal of experimental and clinical research.
2016 Nov; 22(?):4283-4288. doi:
10.12659/msm.897315. [PMID: 27834342] - Shujiang Shang, Feipeng Zhu, Bin Liu, Zuying Chai, Qihui Wu, Meiqin Hu, Yuan Wang, Rong Huang, Xiaoyu Zhang, Xi Wu, Lei Sun, Yeshi Wang, Li Wang, Huadong Xu, Sasa Teng, Bing Liu, Lianghong Zheng, Chen Zhang, Fukang Zhang, Xinghua Feng, Desheng Zhu, Changhe Wang, Tao Liu, Michael X Zhu, Zhuan Zhou. Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons.
The Journal of cell biology.
2016 Nov; 215(3):369-381. doi:
10.1083/jcb.201603081. [PMID: 27799370] - Ralph Kissen, Anders Øverby, Per Winge, Atle M Bones. Allyl-isothiocyanate treatment induces a complex transcriptional reprogramming including heat stress, oxidative stress and plant defence responses in Arabidopsis thaliana.
BMC genomics.
2016 09; 17(1):740. doi:
10.1186/s12864-016-3039-x. [PMID: 27639974] - T Fu, J J Hull, T Yang, G Wang. Identification and functional characterization of four transient receptor potential ankyrin 1 variants in Apolygus lucorum (Meyer-Dür).
Insect molecular biology.
2016 08; 25(4):370-84. doi:
10.1111/imb.12231. [PMID: 27038267] - Amin N Olaimat, Richard A Holley. Inhibition of Listeria monocytogenes on cooked cured chicken breasts by acidified coating containing allyl isothiocyanate or deodorized Oriental mustard extract.
Food microbiology.
2016 Aug; 57(?):90-5. doi:
10.1016/j.fm.2016.02.001. [PMID: 27052706] - Franziska Beran, Guillermo H Jiménez-Alemán, Mei-Ying Lin, Yun-Che Hsu, Inga Mewis, Ramasamy Srinivasan, Christian Ulrichs, Wilhelm Boland, Bill S Hansson, Andreas Reinecke. The Aggregation Pheromone of Phyllotreta striolata (Coleoptera: Chrysomelidae) Revisited.
Journal of chemical ecology.
2016 Aug; 42(8):748-755. doi:
10.1007/s10886-016-0743-6. [PMID: 27518387] - Meejung Ahn, Jeongtae Kim, Hyojin Bang, Jihwan Moon, Gi Ok Kim, Taekyun Shin. Hepatoprotective effects of allyl isothiocyanate against carbon tetrachloride-induced hepatotoxicity in rat.
Chemico-biological interactions.
2016 Jul; 254(?):102-8. doi:
10.1016/j.cbi.2016.05.037. [PMID: 27241356] - Sayaka Suzawa, Kenji Takahashi, Takahisa Shimada, Toshio Ohta. Carbonyl stress-induced 5-hydroxytriptamine secretion from RIN-14B, rat pancreatic islet tumor cells, via the activation of transient receptor potential ankyrin 1.
Brain research bulletin.
2016 07; 125(?):181-6. doi:
10.1016/j.brainresbull.2016.07.005. [PMID: 27423812] - Li-Yun Lin, Kun-Hung Shen, Xiang-Yü Yeh, Bou-Yü Huang, Hui-Er Wang, Kuan-Chou Chen, Robert Y Peng. Integrated Process for Production of Galangal Acetate, the 'Wasabi-Like' Spicy Compound, and Analysis of Essential Oils of Rhizoma Alpinia officinarum (Hance) Farw.
Journal of food science.
2016 Jun; 81(6):H1565-75. doi:
10.1111/1750-3841.13326. [PMID: 27166764] - Sándor Gonda, Attila Kiss-Szikszai, Zsolt Szűcs, Nhat Minh Nguyen, Gábor Vasas. Myrosinase Compatible Simultaneous Determination of Glucosinolates and Allyl Isothiocyanate by Capillary Electrophoresis Micellar Electrokinetic Chromatography (CE-MEKC).
Phytochemical analysis : PCA.
2016 May; 27(3-4):191-8. doi:
10.1002/pca.2615. [PMID: 27313156] - Jin-Feng Zhao, Song-Kun Shyue, Yu Ru Kou, Tse-Min Lu, Tzong-Shyuan Lee. Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation.
International journal of biological sciences.
2016; 12(7):812-23. doi:
10.7150/ijbs.15229. [PMID: 27313495] - Bjørnar Sporsheim, Anders Øverby, Atle Magnar Bones. Allyl Isothiocyanate Inhibits Actin-Dependent Intracellular Transport in Arabidopsis thaliana.
International journal of molecular sciences.
2015 Dec; 16(12):29134-47. doi:
10.3390/ijms161226154. [PMID: 26690132] - Juan M Quiles, Lara Manyes, Fernando Luciano, Jordi Mañes, Giuseppe Meca. Influence of the antimicrobial compound allyl isothiocyanate against the Aspergillus parasiticus growth and its aflatoxins production in pizza crust.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2015 Sep; 83(?):222-8. doi:
10.1016/j.fct.2015.06.017. [PMID: 26146190] - Juyoung Lee, Hoonjeong Kwon. In vitro metabolic conversion of the organic breakdown products of glucosinolate to goitrogenic thiocyanate anion.
Journal of the science of food and agriculture.
2015 Aug; 95(11):2244-51. doi:
10.1002/jsfa.6943. [PMID: 25271103] - Yuko Terada, Hideki Masuda, Tatsuo Watanabe. Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard.
Journal of natural products.
2015 Aug; 78(8):1937-41. doi:
10.1021/acs.jnatprod.5b00272. [PMID: 26263397] - J J Wei, T Fu, T Yang, Y Liu, G R Wang. A TRPA1 channel that senses thermal stimulus and irritating chemicals in Helicoverpa armigera.
Insect molecular biology.
2015 Aug; 24(4):412-21. doi:
10.1111/imb.12168. [PMID: 25827167] - Anika E Wagner, Christine Sturm, Stefanie Piegholdt, Insa M A Wolf, Tuba Esatbeyoglu, Gina Rosalinda De Nicola, Renato Iori, Gerald Rimbach. Myrosinase-treated glucoerucin is a potent inducer of the Nrf2 target gene heme oxygenase 1--studies in cultured HT-29 cells and mice.
The Journal of nutritional biochemistry.
2015 Jun; 26(6):661-6. doi:
10.1016/j.jnutbio.2015.01.004. [PMID: 25776458] - Amin N Olaimat, Richard A Holley. Control of Salmonella on fresh chicken breasts by κ-carrageenan/chitosan-based coatings containing allyl isothiocyanate or deodorized Oriental mustard extract plus EDTA.
Food microbiology.
2015 Jun; 48(?):83-8. doi:
10.1016/j.fm.2014.11.019. [PMID: 25790995] - Hua Wu, Na Xue, Chang-liang Hou, Jun-tao Feng, Xing Zhang. Microcapsule preparation of allyl isothiocyanate and its application on mature green tomato preservation.
Food chemistry.
2015 May; 175(?):344-9. doi:
10.1016/j.foodchem.2014.11.149. [PMID: 25577090] - Thangarasu Rajakumar, Pachaiappan Pugalendhi, Subbaiyan Thilagavathi. Dose response chemopreventive potential of allyl isothiocyanate against 7,12-dimethylbenz(a)anthracene induced mammary carcinogenesis in female Sprague-Dawley rats.
Chemico-biological interactions.
2015 Apr; 231(?):35-43. doi:
10.1016/j.cbi.2015.02.015. [PMID: 25744308] - Kanako Miyano, Kouichiro Minami, Toru Yokoyama, Katsuya Ohbuchi, Takuhiro Yamaguchi, Satoshi Murakami, Seiji Shiraishi, Masahiro Yamamoto, Motohiro Matoba, Yasuhito Uezono. Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
Anesthesia and analgesia.
2015 Apr; 120(4):790-8. doi:
10.1213/ane.0000000000000625. [PMID: 25642661] - Kang-Mo Ku, Elizabeth H Jeffery, John A Juvik, Mosbah M Kushad. Correlation of quinone reductase activity and allyl isothiocyanate formation among different genotypes and grades of horseradish roots.
Journal of agricultural and food chemistry.
2015 Mar; 63(11):2947-55. doi:
10.1021/jf505591z. [PMID: 25684599] - André Luiz Ventura Sávio, Glenda Nicioli da Silva, Daisy Maria Fávero Salvadori. Inhibition of bladder cancer cell proliferation by allyl isothiocyanate (mustard essential oil).
Mutation research.
2015 Jan; 771(?):29-35. doi:
10.1016/j.mrfmmm.2014.11.004. [PMID: 25771977] - Yang-Ji Kim, Da-Hye Lee, Jiyun Ahn, Woo-Jae Chung, Young Jin Jang, Ki-Seung Seong, Jae-Hak Moon, Tae Youl Ha, Chang Hwa Jung. Pharmacokinetics, Tissue Distribution, and Anti-Lipogenic/Adipogenic Effects of Allyl-Isothiocyanate Metabolites.
PloS one.
2015; 10(8):e0132151. doi:
10.1371/journal.pone.0132151. [PMID: 26317351] - Muhammad Abdus Sobahan, Nasima Akter, Eiji Okuma, Misugi Uraji, Wenxiu Ye, Izumi C Mori, Yoshimasa Nakamura, Yoshiyuki Murata. Allyl isothiocyanate induces stomatal closure in Vicia faba.
Bioscience, biotechnology, and biochemistry.
2015; 79(10):1737-42. doi:
10.1080/09168451.2015.1045827. [PMID: 26027691] - Amin N Olaimat, Babak Sobhi, Richard A Holley. Influence of temperature, glucose, and iron on sinigrin degradation by Salmonella and Listeria monocytogenes.
Journal of food protection.
2014 Dec; 77(12):2133-8. doi:
10.4315/0362-028x.jfp-14-210. [PMID: 25474062] - Amin N Olaimat, Yuan Fang, Richard A Holley. Inhibition of Campylobacter jejuni on fresh chicken breasts by κ-carrageenan/chitosan-based coatings containing allyl isothiocyanate or deodorized oriental mustard extract.
International journal of food microbiology.
2014 Sep; 187(?):77-82. doi:
10.1016/j.ijfoodmicro.2014.07.003. [PMID: 25058687] - Katrina W Copeland, Alessandro A Boezio, Eugene Cheung, Josie Lee, Philip Olivieri, Laurie B Schenkel, Qian Wan, Weiya Wang, Mary C Wells, Beth Youngblood, Narender R Gavva, Sonya G Lehto, Stephanie Geuns-Meyer. Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
Bioorganic & medicinal chemistry letters.
2014 Aug; 24(15):3464-8. doi:
10.1016/j.bmcl.2014.05.069. [PMID: 24953819] - Do-Seop Lee, Tae-Ho Kim, Yi-Sook Jung. Inhibitory effect of allyl isothiocyanate on platelet aggregation.
Journal of agricultural and food chemistry.
2014 Jul; 62(29):7131-9. doi:
10.1021/jf4041518. [PMID: 24980285] - André Luiz Ventura Savio, Glenda Nicioli da Silva, Elaine Aparecida de Camargo, Daisy Maria Fávero Salvadori. Cell cycle kinetics, apoptosis rates, DNA damage and TP53 gene expression in bladder cancer cells treated with allyl isothiocyanate (mustard essential oil).
Mutation research.
2014 Apr; 762(?):40-6. doi:
10.1016/j.mrfmmm.2014.02.006. [PMID: 24625788] - Amin N Olaimat, Richard A Holley. Inhibition of Listeria monocytogenes and Salmonella by combinations of oriental mustard, malic acid, and EDTA.
Journal of food science.
2014 Apr; 79(4):M614-21. doi:
10.1111/1750-3841.12411. [PMID: 24649979] - G Chung, S T Im, Y H Kim, S J Jung, M-R Rhyu, S B Oh. Activation of transient receptor potential ankyrin 1 by eugenol.
Neuroscience.
2014 Mar; 261(?):153-60. doi:
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