Scoparon (BioDeep_00000861045)

PANOMIX_OTCML-2023

代谢物信息卡片

5-18-03-00204 (Beilstein Handbook Reference)

化学式: C11H10O4 (206.057906)
中文名称: 滨蒿内酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C=C2C(=C1)C=CC(=O)O2)OC
InChI: InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3

描述信息

D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].
Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

同义名列表

30 个代谢物同义名

5-18-03-00204 (Beilstein Handbook Reference); Benzopyran-2-one, 6,7-dimethoxy- (9CI); 2H-1-Benzopyran-2-one, 6,7-dimethoxy-; 6,7-Dimethoxy-2H-1-benzopyran-2-one; 6,7-Dimethoxybenzopyran-2-one; 6,7-Dimethoxy-2-benzopyrone; 6,7-dimethoxychromen-2-one; 6,7-dimethoxy-2-chromenone; Aesculetin dimethyl ether; Esculetin dimethyl ether; Coumarin, 6,7-dimethoxy-; Scopoletin methyl ether; 6,7-dimethoxycoumarin; 6,7-dimethylesculetin; Maybridge4_003009; EINECS 204-369-0; SR-01000631300-1; 254886_ALDRICH; MEGxp0_001422; ZINC00002067; ACon1_002079; AIDS-026315; BRN 0169572; AIDS026315; Escoparone; Scoparone; ST5319943; 120-08-1; Scoparon; C09311

数据库引用编号

10 个数据库交叉引用编号

ChEBI: CHEBI:9055
KEGG: C09311
PubChem: 8417
ChEMBL: CHEMBL325864
CAS: 120-08-1
PubChem: 11502
KNApSAcK: C00002498
3DMET: B02851
NIKKAJI: J5.319H
medchemexpress: HY-N0228

分类词条

苯丙素类

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

153 个相关的物种来源信息

282723 - Achillea biserrata: 10.1007/BF00579679
282741 - Achillea impatiens: 10.1007/BF00579978
282761 - Achillea ptarmicifolia: 10.1007/BF00579978
68527 - Aegle marmelos: 10.1016/J.PHYTOCHEM.2011.11.018
416184 - Aeglopsis chevalieri: 10.1021/JO01273A076
231460 - Afraegle paniculata: 10.1016/0031-9422(73)85149-0
430971 - Agathosma capensis: 10.1016/0031-9422(86)88018-9
2486844 - Agathosma ciliaris: 10.1016/0031-9422(86)88018-9
1641042 - Agathosma imbricata: 10.1016/0031-9422(86)88018-9
2486847 - Agathosma lanceolata: 10.1016/0031-9422(86)88018-9
2486848 - Agathosma martiana: 10.1016/0031-9422(86)88018-9
2805000 - Aldama robusta: 10.1016/0305-1978(96)00057-9
2805006 - Aldama tukumanensis: 10.1016/0031-9422(95)00584-6
123498 - Aleurites moluccanus: 10.1016/S0367-326X(00)00314-2
403096 - Allamanda schottii: 10.1021/NP50056A018
665671 - Anisotome pilifera: 10.1016/S0305-1978(02)00047-9
4045 - Apium graveolens: 10.1007/BF00993733
137934 - Aralia bipinnata:
401875 - Artemisia adamsii: 10.1016/S0031-9422(00)83171-4
35608 - Artemisia Annua L.: -
262982 - Artemisia apiacea: 10.1016/S0367-326X(02)00070-9
259893 - Artemisia argyi Lévl.et Vant.: -
72337 - Artemisia campestris: 10.1016/0031-9422(91)83491-3
265783 - Artemisia capillaris:
265783 - Artemisia capillaris Thunb.: -
496566 - Artemisia carvifolia: 10.1016/S0367-326X(02)00070-9
205364 - Artemisia dracunculoides: 10.1016/S0031-9422(00)85199-7
72341 - Artemisia dracunculus:
401909 - Artemisia laciniata: 10.1002/JLAC.198619861208
205371 - Artemisia marschalliana: 10.1016/S0031-9422(00)88402-2
72349 - Artemisia nova: 10.1016/S0021-9673(01)97678-2
72350 - Artemisia reptans: 10.1016/S0031-9422(00)89536-9
72351 - Artemisia scoparia:
72351 - Artemisia scoparia Waldst.et Kit.: -
55611 - Artemisia tridentata: 10.1016/0305-1978(92)90072-L
1177126 - Artemisia turanica: 10.1021/NP50031A025
1811969 - Artemisia vestita: 10.1055/S-1999-13965
48103 - Bupleurum fruticosum: 10.1016/0031-9422(95)00749-0
199751 - Bupleurum salicifolium:
1475378 - Calea ternifolia: 10.3390/MOLECULES22020289
68535 - Casimiroa edulis: 10.1021/NP50037A032
60419 - Castanea mollissima: 10.1080/10286020903451757
136894 - Catunaregam spinosa: 10.1002/CHIN.200844208
864332 - Cedrelopsis grevei:
145490 - Centaurea collina: 10.1016/S0031-9422(00)97993-7
145515 - Centaurea salonitana: 10.1016/S0031-9422(00)97993-7
557631 - Chiliadenus candicans: 10.3109/13880208809053916
558547 - Citrus deliciosa:
64884 - Citrus jambhiri: 10.1094/PHYTO-78-1678
76966 - Citrus japonica: 10.1248/CPB.49.1356
408488 - Citrus kinokuni: 10.1248/CPB.49.1356
307630 - Citrus macrophylla:
171251 - Citrus medica:
85571 - Citrus reticulata:
237573 - Citrus sulcata: 10.1248/CPB.39.2509
488172 - Citrus tamurana: 10.1016/S0031-9422(98)00247-7
37690 - Citrus trifoliata:
55188 - Citrus unshiu: 10.1007/BF00630620
475932 - Citrus wilsonii: 10.1016/S0031-9422(98)00247-7
4047 - Coriandrum sativum: 10.1016/0031-9422(95)00930-2
4129 - Cuscuta reflexa: -
4129 - Cuscuta reflexa: 10.1248/CPB.50.112
906689 - Dendrobium catenatum: 10.1021/JF040017R
161866 - Dendrobium densiflorum:
142614 - Dendrobium moniliforme: 10.1021/JF040017R
142615 - Dendrobium officinale: 10.1021/JF040017R
117978 - Dendrobium thyrsiflorum:
183483 - Dendrobium tosaense: 10.1021/JF040017R
489439 - Deverra tortuosa: 10.1590/S0103-50532003000100008
298346 - Dictamnus albus: 10.1016/S0031-9422(98)00519-6
167917 - Duranta erecta: 10.1248/CPB.50.515
105886 - Eleutherococcus sessiliflorus: 10.1055/S-2002-34925
378924 - Empleurum unicapsulare: 10.1016/0031-9422(86)88018-9
2894177 - Empleurum unicapsularis: 10.1016/0031-9422(86)88018-9
2589437 - Erythroxylum barbatum: 10.1016/S0305-1978(02)00249-1
1873686 - Espeletia spectabilis: 10.1016/0031-9422(80)83072-X
318062 - Euphorbia hirta: 10.1016/S1875-5364(12)60009-0
756622 - Euphorbia iberica: 10.1055/S-2006-960819
371331 - Ferula badhysi: 10.1007/BF00567821
371362 - Ferula linkii: 10.1016/0031-9422(93)85291-X
371375 - Ferula oopoda: 10.1007/BF00567821
126418 - Forsythia suspensa (Thunb.) Vahl: -
38874 - Fraxinus ornus:
469925 - Garcinia conrauana: 10.1021/NP8006364
469930 - Garcinia kola: 10.1021/NP8006364
1009474 - Garcinia multiflora: 10.1021/NP8006364
114476 - Gardenia jasminoides: 10.1021/NP800002Z
63806 - Gomortega keule: 10.1016/0031-9422(91)83506-G
127995 - Gonospermum ferulaceum: 10.1016/0031-9422(90)83068-C
127982 - Gonospermum fruticosum:
127983 - Gonospermum gomerae: 10.1021/NP800474V
1006079 - Haplophyllum ramosissimum:
1006083 - Haplophyllum thesioides: 10.1080/10575639308050059
1898877 - Hibiscus taiwanensis:
549422 - Hortia longifolia: 10.1021/JO00829A053
180498 - Jatropha curcas: 10.1002/HLCA.201000313
271244 - Keetia multiflora: 10.1055/S-2008-1034372
587579 - Khaya senegalensis: 10.1016/0031-9422(95)00093-3
85854 - Magnolia coco:
3406 - Magnolia grandiflora: 10.1016/S0031-9422(00)80557-9
3411 - Magnolia salicifolia: 10.1248/CPB.39.3265
155640 - Melia azedarach: 10.1016/S0367-326X(99)00051-9
1487095 - Melicope borbonica: 10.1016/S0378-8741(98)00137-8
28525 - Menyanthes trifoliata: 10.1086/325638
1048568 - Metalasia capitata: 10.1016/0031-9422(90)83033-W
1048565 - Metalasia cephalotes: 10.1016/0031-9422(90)83033-W
1089418 - Microtropis japonica:
126552 - Olea capensis:
176559 - Pericome caudata: 10.1016/S0031-9422(00)82480-2
282633 - Phebalium squamulosum: 10.1016/0031-9422(92)83450-D
68554 - Phellodendron amurense:
271192 - Pimpinella anisum: 10.1007/BF00993733
1008928 - Pittosporum illicioides: 10.1021/NP8004503
33090 - Plants: -
557757 - Platymiscium yucatanum: 10.1515/HFSG.1998.52.5.459
81514 - Pterocaulon sphacelatum: 10.1071/CH9683079
119185 - Pulicaria arabica: 10.3109/13880208809053916
286923 - Ranunculus laetus: 10.1007/S10600-009-9408-9
147635 - Ranunculus sceleratus: 10.1055/S-2005-873169
376251 - Ranunculus sieboldii: 10.1055/S-2005-873169
1905583 - Rubia wallichiana:
452789 - Ruta angustifolia: 10.1016/S0031-9422(00)84991-2
238933 - Saussurea brunneopilosa: 10.3109/13880209409083006
378320 - Saussurea eopygmaea: 10.3109/13880209409083006
354518 - Skimmia laureola: 10.1016/S0031-9422(00)81759-8
329772 - Solanum dasyphyllum: 10.1021/NP50037A033
126913 - Suaeda maritima: 10.1002/JPS.3030350906
1735025 - Suaeda nudiflora: 10.1002/JPS.3030350906
169606 - Tagetes lucida: 10.1021/JF053071W
183267 - Talipariti tiliaceum: 10.1248/CPB.53.56
23278 - Vahlia capensis: 10.1016/0031-9422(94)00710-B
159071 - Zanthoxylum ailanthoides:
354527 - Zanthoxylum avicennae:
1056465 - Zanthoxylum beecheyanum: 10.1002/JCCS.200400159
2839964 - Zanthoxylum dimorphophyllum: 10.1515/ZNC-2001-7-802
992815 - Zanthoxylum leprieurii: 10.1021/NP50048A057
354528 - Zanthoxylum nitidum:
354530 - Zanthoxylum schinifolium:
328402 - Zanthoxylum simulans: 10.1016/S0031-9422(97)00280-X
2099548 - Zanthoxylum zanthoxyloides: 10.1021/NP50046A035
380129 - 佛手: -
33090 - 半边莲: -
33090 - 川牛膝: -
33090 - 枸骨叶: -
33090 - 柴胡: -
33090 - 白头翁: -
33090 - 肿节风: -
33090 - 艾叶: -
33090 - 茵陈: -
33090 - 葛根: -
33090 - 葛花: -
33090 - 青果: -
496566 - 青蒿: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Tianyi Zhao, Shiyi Lun, Maoying Yan, JongPil Park, Shumin Wang, Changbao Chen. 6,7-Dimethoxycoumarin, Gardenoside and Rhein combination improves non-alcoholic fatty liver disease in rats. Journal of ethnopharmacology. 2024 Mar; 322(?):117646. doi: 10.1016/j.jep.2023.117646. [PMID: 38135236]
Jinxiang Luo, Huijun Xie, Wei Ding, Yongqiang Zhang. Photodegradation of the pure and formulated scoparone in liquid solutions: kinetics and mechanism. Environmental technology. 2024 Jan; 45(1):87-98. doi: 10.1080/09593330.2022.2099312. [PMID: 35796037]
Sha Huang, Luping Lin, Yifei Ma, Qing Zhu, Ningna Weng. Scoparone induces autophagic cell death via the PAK1/AKT axis in colorectal cancer. European journal of pharmacology. 2023 Oct; 959(?):176091. doi: 10.1016/j.ejphar.2023.176091. [PMID: 37805132]
Miaoqing Ye, Chunyan Liu, Jiaojiao Liu, Fenping Lu, Jingdong Xue, Fenping Li, Yinghui Tang. Scoparone inhibits the development of hepatocellular carcinoma by modulating the p38 MAPK/Akt/NF-κB signaling in nonalcoholic fatty liver disease mice. Environmental toxicology. 2023 Jul; ?(?):. doi: 10.1002/tox.23851. [PMID: 37436232]
Hongping Shen, Yiting Wei, Qunying Yang, Yili Cai, Keqi Zhu, Xueqin Chen. Scoparone induces both apoptosis and ferroptosis via multiple mechanisms in non-small-cell lung cancer cells. Toxicology in vitro : an international journal published in association with BIBRA. 2023 Jun; 91(?):105627. doi: 10.1016/j.tiv.2023.105627. [PMID: 37315743]
Juan Zou, Yuanyuan Li, Jingyi Cai, Xiaotian Peng, Lincong Zhang, Tian Tian, Tianming Wang, Rong Shi, Jiasheng Wu, Yueming Ma. Identification of Yinchenwuling fang's active components and hepatoprotective effects against cholestatic liver damage induced by alpha-naphthyl isothiocyanate in mice. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2023 Jan; 1215(?):123570. doi: 10.1016/j.jchromb.2022.123570. [PMID: 36542898]
Min Wei, Ting Li, Houkang Cao, Haiyan He, Chaoyue Yang, Yifan Yin, Huijie Lu, Petr Novák, Kefeng Zhang, Ya Gao. The effects of scoparone on alcohol and high-fat diet-induced liver injury revealed by RNA sequencing. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Nov; 155(?):113770. doi: 10.1016/j.biopha.2022.113770. [PMID: 36182737]
Kyung-Ran Park, Bomi Kim, Joon Yeop Lee, Ho-Jin Moon, Il Keun Kwon, Hyung-Mun Yun. Effects of Scoparone on differentiation, adhesion, migration, autophagy and mineralization through the osteogenic signalling pathways. Journal of cellular and molecular medicine. 2022 08; 26(16):4520-4529. doi: 10.1111/jcmm.17476. [PMID: 35796406]
Hong Zhou, Fenglin Wan, Fuyou Guo, Jinlin Liu, Wei Ding. High value-added application of a renewable bioresource as acaricide: Investigation the mechanism of action of scoparone against Tetranychus cinnabarinus. Journal of advanced research. 2022 05; 38(?):29-39. doi: 10.1016/j.jare.2021.08.013. [PMID: 35572395]
Joanna Kowalczyk, Barbara Budzyńska, Łukasz Kurach, Daniele Pellegata, Nesrine S El Sayed, Jürg Gertsch, Krystyna Skalicka-Woźniak. Neuropsychopharmacological profiling of scoparone in mice. Scientific reports. 2022 01; 12(1):822. doi: 10.1038/s41598-021-04741-3. [PMID: 35039558]
Xiaoyan Huang, Ya Gao, Houkang Cao, Jun Li, Siyi Mo, Ting Li, Jianzhao Wu, Kai Guo, Riming Wei, Kefeng Zhang. Effects of scoparone on non-alcoholic fatty liver disease revealed by RNA sequencing. Frontiers in endocrinology. 2022; 13(?):1004284. doi: 10.3389/fendo.2022.1004284. [PMID: 36157436]
Hong Zhou, Jinlin Liu, Fenglin Wan, Fuyou Guo, Yeshuang Ning, Sisi Liu, Wei Ding. Insight into the mechanism of action of scoparone inhibiting egg development of Tetranychus cinnabarinus Boisduval. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2021 Aug; 246(?):109055. doi: 10.1016/j.cbpc.2021.109055. [PMID: 33894369]
Linmao Lyu, Jiazheng Chen, Wei Wang, Tao Yan, Jiamao Lin, Hongmei Gao, Hui Li, Ruijuan Lv, Feng Xu, Lijun Fang, Yuguo Chen. Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. Journal of cellular and molecular medicine. 2021 03; 25(6):3136-3148. doi: 10.1111/jcmm.16304. [PMID: 33560596]
Yang-Liu Xia, Jing-Jing Wang, Shi-Yang Li, Yong Liu, Frank J Gonzalez, Ping Wang, Guang-Bo Ge. Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment. Bioorganic & medicinal chemistry. 2021 01; 29(?):115851. doi: 10.1016/j.bmc.2020.115851. [PMID: 33218896]
Monterrosas-Brisson Nayeli, Herrera-Ruiz Maribel, Jiménez-Ferrer Enrique, Bahena-Pérez Rafael, Avilés-Flores Margarita, Fuentes-Mata Macrina, Martínez-Duncker Ivan, González-Cortazar Manasés. Anti-inflammatory activity of coumarins isolated from Tagetes lucida Cav. Natural product research. 2020 Nov; 34(22):3244-3248. doi: 10.1080/14786419.2018.1553172. [PMID: 30618303]
Yangyang Hui, Xiaoyu Wang, Zihan Yu, Xiaofei Fan, Binxin Cui, Tianming Zhao, Lihong Mao, Hongjuan Feng, Lin Lin, Qingxiang Yu, Jie Zhang, Bangmao Wang, Xin Chen, Xingliang Zhao, Chao Sun. Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action. Pharmacological research. 2020 10; 160(?):105170. doi: 10.1016/j.phrs.2020.105170. [PMID: 32877694]
Beibei Liu, Xiaoling Deng, Qianqian Jiang, Guixin Li, Junli Zhang, Ning Zhang, Shengliang Xin, Keshu Xu. Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 May; 125(?):109895. doi: 10.1016/j.biopha.2020.109895. [PMID: 32000066]
Yijun Yao, Feiran Xu, Xingrong Ju, Zhifang Li, Lifeng Wang. Lipid-Lowering Effects and Intestinal Transport of Polyphenol Extract from Digested Buckwheat in Caco-2/HepG2 Coculture Models. Journal of agricultural and food chemistry. 2020 Apr; 68(14):4205-4214. doi: 10.1021/acs.jafc.0c00321. [PMID: 32141744]
Akram Taleghani, Seyed Ahmad Emami, Zahra Tayarani-Najaran. Artemisia: a promising plant for the treatment of cancer. Bioorganic & medicinal chemistry. 2020 01; 28(1):115180. doi: 10.1016/j.bmc.2019.115180. [PMID: 31784199]
Seung Hyo Jung, Gyoung Beom Lee, Yunkyoung Ryu, Long Cui, Hwan Myung Lee, Junghwan Kim, Bokyung Kim, Kyung Jong Won. Inhibitory effects of scoparone from chestnut inner shell on platelet-derived growth factor-BB-induced vascular smooth muscle cell migration and vascular neointima hyperplasia. Journal of the science of food and agriculture. 2019 Jul; 99(9):4397-4406. doi: 10.1002/jsfa.9674. [PMID: 30861122]
Risto O Juvonen, Filip Novák, Eleni Emmanouilidou, Seppo Auriola, Juri Timonen, Aki T Heikkinen, Jenni Küblbeck, Moshe Finel, Hannu Raunio. Metabolism of Scoparone in Experimental Animals and Humans. Planta medica. 2019 Apr; 85(6):453-464. doi: 10.1055/a-0835-2301. [PMID: 30736072]
Chang Liu, Shuang Li, Qingkai Zhang, Fangyue Guo, Mengying Tong, Maria Francesca Ysabelle M Martinez, Heather H Wang, Yutong Zhao, Dong Shang. Emerging Role of Chinese Herbal Medicines in the Treatment of Pancreatic Fibrosis. The American journal of Chinese medicine. 2019; 47(4):709-726. doi: 10.1142/s0192415x1950037x. [PMID: 31091974]
Tun-Pin Hsueh, Tung-Hu Tsai. Preclinical Pharmacokinetics of Scoparone, Geniposide and Rhein in an Herbal Medicine Using a Validated LC-MS/MS Method. Molecules (Basel, Switzerland). 2018 Oct; 23(10):. doi: 10.3390/molecules23102716. [PMID: 30360359]
Anam Fayyaz, Seddy Makwinja, Seppo Auriola, Hannu Raunio, Risto O Juvonen. Comparison of In Vitro Hepatic Scoparone 7-O-Demethylation between Humans and Experimental Animals. Planta medica. 2018 Mar; 84(5):320-328. doi: 10.1055/s-0043-119886. [PMID: 28950382]
Yu-Yi Chan, Tsong-Long Hwang, Ping-Chung Kuo, Hsin-Yi Hung, Tian-Shung Wu. Constituents of the Fruits of Citrus medica L. var. sarcodactylis and the Effect of 6,7-Dimethoxy-coumarin on Superoxide Anion Formation and Elastase Release. Molecules (Basel, Switzerland). 2017 Sep; 22(9):. doi: 10.3390/molecules22091454. [PMID: 28862688]
Tasmia Tahsin, Jean Duplex Wansi, Afaf Al-Groshi, Andrew Evans, Lutfun Nahar, Claire Martin, Satyajit Dey Sarker. Cytotoxic Properties of the Stem Bark of Citrus reticulata Blanco (Rutaceae). Phytotherapy research : PTR. 2017 Aug; 31(8):1215-1219. doi: 10.1002/ptr.5842. [PMID: 28568378]
Ruijie He, Shengping Deng, Hui Nie, Yan Huang, Buming Liu, Ruiyun Yang, Shuai Huang, Dexiong Zhou, Huangcan Chen, Jun Li, Yanjun Zhang. Two new coumarins from the bark of Streblus indicus (Bur.) Corner. Natural product research. 2017 May; 31(9):1052-1058. doi: 10.1080/14786419.2016.1269098. [PMID: 28013566]
Jian-Yuan Li, Hong-Yan Cao, Lin Sun, Run-Fei Sun, Chao Wu, Yan-Qin Bian, Shu Dong, Ping Liu, Ming-Yu Sun. Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases. World journal of gastroenterology. 2017 Feb; 23(7):1125-1138. doi: 10.3748/wjg.v23.i7.1125. [PMID: 28275293]
Sang-Hyun Lee, Jung-Yun Lee, Young-In Kwon, Hae-Dong Jang. Anti-Osteoclastic Activity of Artemisia capillaris Thunb. Extract Depends upon Attenuation of Osteoclast Differentiation and Bone Resorption-Associated Acidification Due to Chlorogenic Acid, Hyperoside, and Scoparone. International journal of molecular sciences. 2017 Feb; 18(2):. doi: 10.3390/ijms18020322. [PMID: 28165389]
Duk-Yeon Cho, Hyun Myung Ko, Joonsoo Kim, Byung-Wook Kim, Yo-Sep Yun, Jeong-In Park, Palanivel Ganesan, Jin-Tae Lee, Dong-Kug Choi. Scoparone Inhibits LPS-Simulated Inflammatory Response by Suppressing IRF3 and ERK in BV-2 Microglial Cells. Molecules (Basel, Switzerland). 2016 Dec; 21(12):. doi: 10.3390/molecules21121718. [PMID: 27983636]
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