NCBI Taxonomy: 1006083

Haplophyllum thesioides (ncbi_taxid: 1006083)

found 28 associated metabolites at species taxonomy rank level.

Ancestor: Haplophyllum

Child Taxonomies: none taxonomy data.

Scoparone

6,7-dimethoxychromen-2-one

C11H10O4 (206.0579)


Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. It has a role as a plant metabolite, an anti-inflammatory agent, an antilipemic drug, an immunosuppressive agent, an antihypertensive agent and an anti-allergic agent. It is a member of coumarins and an aromatic ether. It is functionally related to an esculetin. Scoparone is a natural product found in Haplophyllum ramosissimum, Haplophyllum thesioides, and other organisms with data available. A member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics Scoparone is found in anise. Scoparone is found in several citrus oil D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Found in several citrus oils Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

   

Angustifoline

(1R,2R,9S,10S)-10-Prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one

C14H22N2O (234.1732)


Angustifoline is a member of quinolizidines and a cyclic ketone. 4-(Prop-2-en-1-yl)decahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one is a natural product found in Haplophyllum thesioides, Lupinus hintonii, and other organisms with data available. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 54 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 18 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 33 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 40 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 25 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 10 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 3

   
   

Skimmianine

4,7,8-trimethoxy-furo(2,3-b)quinoline

C14H13NO4 (259.0845)


Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

Flindersine

Flindersine

C14H13NO2 (227.0946)


relative retention time with respect to 9-anthracene Carboxylic Acid is 1.139 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.140

   

Haplopine

4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol; 7-Hydroxy-8-methoxydictamnine

C13H11NO4 (245.0688)


Haplopine is an oxacycle, an organonitrogen heterocyclic compound and an organic heterotricyclic compound. Haplopine is a natural product found in Haplophyllum bucharicum, Haplophyllum cappadocicum, and other organisms with data available.

   

EVOXINE

2,3-Butanediol, 1-((4,8-dimethoxyfuro(2,3-b)quinolin-7-yl)oxy)-3-methyl-, (+)-

C18H21NO6 (347.1369)


   

gamma-Fagarine

4,8-Dimethoxyfuro[2,3-b]quinoline; 8-Methoxydictamnine; Fagarine

C13H11NO3 (229.0739)


Gamma-Fagarine is an organic heterotricyclic compound, an organonitrogen heterocyclic compound and an oxacycle. gamma-Fagarine is a natural product found in Haplophyllum bucharicum, Haplophyllum griffithianum, and other organisms with data available. gamma-Fagarine is found in fruits. gamma-Fagarine is an alkaloid from Aegle marmelos (bael fruit

   

Kokusaginine

Furo(2,3-b)quinoline, 4,6,7-trimethoxy-

C14H13NO4 (259.0845)


   

Skimmianine

InChI=1/C14H13NO4/c1-16-10-5-4-8-11(13(10)18-3)15-14-9(6-7-19-14)12(8)17-2/h4-7H,1-3H

C14H13NO4 (259.0845)


Skimmianine is an organonitrogen heterocyclic compound, an organic heterotricyclic compound, an oxacycle and an alkaloid antibiotic. Skimmianine is a natural product found in Haplophyllum bucharicum, Haplophyllum cappadocicum, and other organisms with data available. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

Seselin

2H-1-Benzopyran-6-acrylic acid, 5-hydroxy-2,2-dimethyl-, .delta.-lactone

C14H12O3 (228.0786)


Seselin is a member of coumarins. It has a role as a metabolite. Seselin is a natural product found in Haplophyllum cappadocicum, Haplophyllum dshungaricum, and other organisms with data available. Constituent of Carum roxburghianum (Bishops weed). Seselin is found in many foods, some of which are sweet orange, herbs and spices, anise, and wild celery. Seselin is found in anise. Seselin is a constituent of Carum roxburghianum (Bishops weed) A natural product found in Citropsis articulata.

   

4-Methoxysalicylic acid

4-Methoxysalicylic acid

C8H8O4 (168.0423)


2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker. 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

   

Pteleine

4,6-dimethoxyfuro[2,3-b]Quinoline, 9ci

C13H11NO3 (229.0739)


Pteleine is found in herbs and spices. Pteleine is an alkaloid tentatively identified in cells of Ruta graveolens (rue) grown in continuous light in liq. medium. Alkaloid tentatively identified in cells of Ruta graveolens (rue) grown in continuous light in liq. medium. Pteleine is found in herbs and spices.

   

NCIOpen2_001552

2-Hydroxy-4-methoxybenzoic acid, 99\\%

C8H8O4 (168.0423)


4-methoxysalicylic acid is a methoxybenzoic acid. 4-Methoxysalicylic acid is a natural product found in Haplophyllum thesioides, Calophyllum polyanthum, and other organisms with data available. 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker. 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

   
   

4-Methoxysalicylic acid

2-Hydroxy-4-methoxybenzoic acid

C8H8O4 (168.0423)


2-hydroxy-4-methoxybenzoic acid belongs to P-methoxybenzoic acids and derivatives class of compounds. Those are benzoic acids in which the hydrogen atom at position 4 of the benzene ring is replaced by a methoxy group. 2-hydroxy-4-methoxybenzoic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 2-hydroxy-4-methoxybenzoic acid can be found in evening primrose, which makes 2-hydroxy-4-methoxybenzoic acid a potential biomarker for the consumption of this food product. 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker. 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

   

Scoparone

6,7-dimethoxycoumarin

C11H10O4 (206.0579)


Annotation level-1 D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

   

Skimmianine

Skimmianine

C14H13NO4 (259.0845)


Origin: Plant; SubCategory_DNP: Alkaloids derived from anthranilic acid, Quinoline alkaloids relative retention time with respect to 9-anthracene Carboxylic Acid is 1.053 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.048 Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

4,6-dimethoxyfuro[2,3-b]quinoline

NCGC00385496-01!4,6-dimethoxyfuro[2,3-b]quinoline

C13H11NO3 (229.0739)


   

Ptelein

4,6-dimethoxyfuro[2,3-b]Quinoline, 9ci

C13H11NO3 (229.0739)


   

γ-Fagarine

gamma-Fagarine

C13H11NO3 (229.0739)


   

Scoparon

5-18-03-00204 (Beilstein Handbook Reference)

C11H10O4 (206.0579)


D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

   

Skimmianin

InChI=1\C14H13NO4\c1-16-10-5-4-8-11(13(10)18-3)15-14-9(6-7-19-14)12(8)17-2\h4-7H,1-3H

C14H13NO4 (259.0845)


Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

Fagarine

4-27-00-02211 (Beilstein Handbook Reference)

C13H11NO3 (229.0739)


   

Kokusaginin

4-27-00-02295 (Beilstein Handbook Reference)

C14H13NO4 (259.0845)


   

(1's,3s,3ar,4r,6's,7'r,7ar,9's)-7'-hydroxy-3-methoxy-7a-methyl-10'-methylidene-hexahydro-3'-oxaspiro[2-benzofuran-4,5'-tricyclo[7.2.1.0¹,⁶]dodecane]-2',11'-dione

(1's,3s,3ar,4r,6's,7'r,7ar,9's)-7'-hydroxy-3-methoxy-7a-methyl-10'-methylidene-hexahydro-3'-oxaspiro[2-benzofuran-4,5'-tricyclo[7.2.1.0¹,⁶]dodecane]-2',11'-dione

C21H28O6 (376.1886)


   

(1r,2r,9s,10s)-10-(prop-2-en-1-yl)-7,11-diazatricyclo[7.3.1.0²,⁷]tridecan-6-one

(1r,2r,9s,10s)-10-(prop-2-en-1-yl)-7,11-diazatricyclo[7.3.1.0²,⁷]tridecan-6-one

C14H22N2O (234.1732)


   

4,5-dimethoxy-11-methylfuro[2,3-c]acridin-6-one

4,5-dimethoxy-11-methylfuro[2,3-c]acridin-6-one

C18H15NO4 (309.1001)