oxolinic acid (BioDeep_00000858353)
代谢物信息卡片
oxolinic acid
化学式: C13H11NO5 (261.0637196)
中文名称: 噁喹酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O
InChI: InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
描述信息
A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo- and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:138856
- KEGGdrug: D02301
- PubChem: 4628
- DrugBank: DB13627
- ChEMBL: CHEMBL416755
- MeSH: Oxolinic Acid
- CAS: 16172-03-5
- CAS: 14698-29-4
- MetaboLights: MTBLC138856
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lawrence M Madikizela, Yannick B Nuapia, Luke Chimuka, Somandla Ncube, Anita Etale. Target and Suspect Screening of Pharmaceuticals and their Transformation Products in the Klip River, South Africa, using Ultra-High-Performance Liquid Chromatography-Mass Spectrometry.
Environmental toxicology and chemistry.
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Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Ana-Madalina Maciuca, Alexandra-Cristina Munteanu, Mirela Mihaila, Mihaela Badea, Rodica Olar, George Mihai Nitulescu, Cristian V A Munteanu, Marinela Bostan, Valentina Uivarosi. Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies.
Molecules (Basel, Switzerland).
2020 Nov; 25(22):. doi:
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Molecular pharmacology.
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Diseases of aquatic organisms.
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2004 Sep; 70(9):5613-20. doi:
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2004 Aug; 69(3):281-8. doi:
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2004 Apr; 322(1-3):243-53. doi:
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2003 06; 26(6):339-47. doi:
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2002 Dec; 40(12):1815-25. doi:
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1980 Jul; 18(1):41-4. doi:
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Radioisotopes.
1979 Nov; 28(11):687-91. doi:
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The Medical journal of Australia.
1979 Apr; 1(8):345-7. doi:
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Minerva medica.
1979 Feb; 70(9):675-8. doi:
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La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris.
1979 Jan; 55(3-4):189-91. doi:
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The New Zealand medical journal.
1978 Oct; 88(622):317-20. doi:
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The Journal of pediatrics.
1978 Sep; 93(3):337-56. doi:
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Pathologie-biologie.
1977 Nov; 25(9):617-21. doi:
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Annales de microbiologie.
1977 Jul; 128B(1):19-33. doi:
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Journal of medicinal chemistry.
1977 Jun; 20(6):791-6. doi:
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American journal of diseases of children (1960).
1977 Jan; 131(1):34-7. doi:
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Therapia Hungarica (English edition).
1977; 25(4):169-72. doi:
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American journal of veterinary research.
1976 May; 37(5):513-6. doi:
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Antimicrobial agents and chemotherapy.
1976 Mar; 9(3):387-92. doi:
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Clinical pharmacology and therapeutics.
1976 Jan; 19(1):37-46. doi:
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British journal of urology.
1975 Apr; 47(2):233-4. doi:
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Gastroenterology.
1974 Aug; 67(2):408-10. doi:
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JAMA.
1973 Dec; 226(13):1525-8. doi:
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Medicine.
1973 Jul; 52(4):265-70. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
1971 Mar; 1(2):193-201. doi:
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