Tefluthrin (BioDeep_00000008438)

   


代谢物信息卡片


(Z)-(1R)-cis-tefluthrin

化学式: C17H14ClF7O2 (418.057)
中文名称: 七氟菊酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=C(C(=C1F)F)COC(=O)C2C(C2(C)C)C=C(C(F)(F)F)Cl)F)F
InChI: InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-

描述信息

同义名列表

4 个代谢物同义名

(Z)-(1R)-cis-tefluthrin; Tefluthrin; Tefluthrin; Tefluthrin



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 PRKX, SLC6A3
Peripheral membrane protein 1 CYP1B1
Endosome membrane 2 CLCN5, SLC6A4
Endoplasmic reticulum membrane 2 CYP1B1, DRD1
Nucleus 2 DRD1, PRKX
cytosol 3 CLCN5, MYL4, TPH2
dendrite 2 DRD2, MAOB
nuclear body 1 SCN1A
nucleoplasm 5 CD2, PRKX, SCN1A, SCN5A, SCNN1G
Cell membrane 13 CD2, CLCN5, DRD1, DRD2, ITLN1, SCN11A, SCN1A, SCN2A, SCN3A, SCN5A, SCN8A, SLC6A3, SLC6A4
Cytoplasmic side 1 MAOB
Cell projection, axon 2 SCN8A, SLC6A3
Multi-pass membrane protein 12 CLCN5, DRD1, DRD2, SCN11A, SCN1A, SCN2A, SCN3A, SCN5A, SCN8A, SCNN1G, SLC6A3, SLC6A4
Golgi apparatus membrane 2 CLCN5, DRD2
Synapse 2 DRD2, SLC6A4
cell junction 2 SCN5A, SCN8A
cell surface 3 CD2, SCN5A, SLC6A3
glutamatergic synapse 4 DRD1, DRD2, SCN2A, SCN8A
Golgi apparatus 2 CD2, CLCN5
Golgi membrane 2 CLCN5, DRD2
lysosomal membrane 1 CLCN5
neuronal cell body 4 MAOB, SCN11A, SCN1A, SLC6A3
presynaptic membrane 5 DRD1, DRD2, SCN2A, SLC6A3, SLC6A4
sarcolemma 1 SCN5A
synaptic vesicle 1 CLCN5
Presynapse 1 SLC6A4
acrosomal vesicle 1 DRD2
plasma membrane 13 CD2, CLCN5, DRD1, DRD2, SCN11A, SCN1A, SCN2A, SCN3A, SCN5A, SCN8A, SCNN1G, SLC6A3, SLC6A4
synaptic vesicle membrane 1 DRD2
Membrane 10 CLCN5, CYP1B1, SCN11A, SCN1A, SCN2A, SCN3A, SCN5A, SCN8A, SLC6A3, SLC6A4
apical plasma membrane 1 SCNN1G
axon 5 DRD2, SCN11A, SCN2A, SCN8A, SLC6A3
caveola 1 SCN5A
extracellular exosome 3 ITLN1, SCN11A, SCNN1G
endoplasmic reticulum 1 SCN5A
extracellular space 2 GNRH1, ITLN1
perinuclear region of cytoplasm 1 SCN5A
intercalated disc 3 SCN1A, SCN2A, SCN5A
mitochondrion 2 CYP1B1, MAOB
protein-containing complex 1 CD2
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 1 CYP1B1
Single-pass type I membrane protein 1 CD2
Secreted 1 ITLN1
extracellular region 3 CD2, GNRH1, ITLN1
cytoplasmic side of plasma membrane 1 CD2
Mitochondrion outer membrane 1 MAOB
mitochondrial outer membrane 1 MAOB
neuronal cell body membrane 1 SLC6A3
anchoring junction 1 SCN8A
ciliary membrane 2 DRD1, DRD2
external side of plasma membrane 2 CD2, SCNN1G
dendritic spine 2 DRD1, DRD2
T-tubule 3 SCN1A, SCN2A, SCN5A
perikaryon 1 DRD2
Z disc 3 SCN1A, SCN5A, SCN8A
cytoplasmic vesicle 1 SCN8A
nucleolus 1 SCN5A
sarcoplasm 1 SCN3A
Early endosome 1 CLCN5
apical part of cell 1 CLCN5
cell-cell junction 1 CD2
postsynaptic membrane 4 DRD1, DRD2, SLC6A3, SLC6A4
presynaptic active zone membrane 1 SCN8A
Apical cell membrane 1 SCNN1G
Cytoplasm, perinuclear region 1 SCN5A
Membrane raft 3 ITLN1, SLC6A3, SLC6A4
Cell junction, focal adhesion 1 SLC6A4
focal adhesion 1 SLC6A4
GABA-ergic synapse 2 DRD1, DRD2
flotillin complex 1 SLC6A3
Cell projection, dendritic spine 1 DRD1
lateral plasma membrane 2 DRD2, SCN5A
receptor complex 1 ITLN1
Cell projection, neuron projection 2 SLC6A3, SLC6A4
neuron projection 3 SLC6A3, SLC6A4, TPH2
cilium 2 DRD1, DRD2
axonal growth cone 1 SCN11A
Cell projection, podosome 1 SCN8A
podosome 1 SCN8A
brush border membrane 1 ITLN1
non-motile cilium 2 DRD1, DRD2
Lipid-anchor, GPI-anchor 1 ITLN1
sperm flagellum 1 DRD2
myosin II complex 1 MYL4
Endomembrane system 1 SLC6A4
sodium channel complex 1 SCNN1G
axon initial segment 2 SCN1A, SCN8A
Cell projection, dendrite 1 DRD1
side of membrane 1 ITLN1
basal plasma membrane 1 SCN3A
Cell membrane, sarcolemma, T-tubule 1 SCN5A
axon terminus 2 DRD2, SLC6A3
endocytic vesicle 1 DRD2
node of Ranvier 3 SCN1A, SCN2A, SCN8A
paranode region of axon 1 SCN2A
mitochondrial envelope 1 MAOB
postsynaptic density membrane 1 SCN8A
Single-pass type IV membrane protein 1 MAOB
parallel fiber to Purkinje cell synapse 1 SCN8A
A band 1 MYL4
Basal cell membrane 1 SCN3A
dopaminergic synapse 2 DRD2, SLC6A3
Cell projection, cilium membrane 1 DRD1
voltage-gated sodium channel complex 6 SCN11A, SCN1A, SCN2A, SCN3A, SCN5A, SCN8A
G protein-coupled receptor complex 2 DRD1, DRD2
serotonergic synapse 1 SLC6A4
C-fiber 1 SCN11A
[Isoform 5]: Cytoplasmic vesicle 1 SCN8A


文献列表

  • Yong Wen, Liangliang Zhou, Da Li, Qi Lai, Haiyan Shi, Minghua Wang. Ecotoxicological effects of the pyrethroid insecticide tefluthrin to the earthworm Eisenia fetida: A chiral view. Environmental research. 2020 11; 190(?):109991. doi: 10.1016/j.envres.2020.109991. [PMID: 32768725]
  • Yong Wen, Zhen Wang, Yingying Gao, Xuejun Zhao, Beibei Gao, Zhaoxian Zhang, Lianshan Li, Zongzhe He, Minghua Wang. Novel Liquid Chromatography-Tandem Mass Spectrometry Method for Enantioseparation of Tefluthrin via a Box-Behnken Design and Its Stereoselective Degradation in Soil. Journal of agricultural and food chemistry. 2019 Oct; 67(42):11591-11597. doi: 10.1021/acs.jafc.9b04888. [PMID: 31557017]
  • Annika Agatz, Mario M Schumann, Bryan W French, Colin D Brown, Stefan Vidal. Assessment of acute toxicity tests and rhizotron experiments to characterize lethal and sublethal control of soil-based pests. Pest management science. 2018 Nov; 74(11):2450-2459. doi: 10.1002/ps.4922. [PMID: 29575759]
  • Veronica Calles-Torrez, Janet J Knodel, Mark A Boetel, Curt D Doetkott, Kellie K Podliska, Joel K Ransom, Patrick Beauzay, B Wade French, Billy W Fuller. Transgenic Bt Corn, Soil Insecticide, and Insecticidal Seed Treatment Effects on Corn Rootworm (Coleoptera: Chrysomelidae) Beetle Emergence, Larval Feeding Injury, and Corn Yield in North Dakota. Journal of economic entomology. 2018 02; 111(1):348-360. doi: 10.1093/jee/tox297. [PMID: 29186516]
  • K D Johnson, L A Campbell, M D Lepping, D M Rule. Field Trial Performance of Herculex XTRA (Cry34Ab1/Cry35Ab1) and SmartStax (Cry34Ab1/Cry35Ab1 + Cry3Bb1) Hybrids and Soil Insecticides Against Western and Northern Corn Rootworms (Coleoptera: Chrysomelidae). Journal of economic entomology. 2017 06; 110(3):1062-1069. doi: 10.1093/jee/tox099. [PMID: 28430986]
  • Adriano E Pereira, Dariane Souza, Sarah N Zukoff, Lance J Meinke, Blair D Siegfried. Cross-resistance and synergism bioassays suggest multiple mechanisms of pyrethroid resistance in western corn rootworm populations. PloS one. 2017; 12(6):e0179311. doi: 10.1371/journal.pone.0179311. [PMID: 28628635]
  • Bingjun He, David M Soderlund. Effects of the β1 auxiliary subunit on modification of Rat Na(v)1.6 sodium channels expressed in HEK293 cells by the pyrethroid insecticides tefluthrin and deltamethrin. Toxicology and applied pharmacology. 2016 Jan; 291(?):58-69. doi: 10.1016/j.taap.2015.12.007. [PMID: 26708501]
  • Daniel L Frank, Ryan Kurtz, Nicholas A Tinsley, Aaron J Gassmann, Lance J Meinke, Daniel Moellenbeck, Michael E Gray, Larry W Bledsoe, Christian H Krupke, Ronald E Estes, Patrick Weber, Bruce E Hibbard. Effect of Seed Blends and Soil-Insecticide on Western and Northern Corn Rootworm Emergence from mCry3A+eCry3.1Ab Bt Maize. Journal of economic entomology. 2015 Jun; 108(3):1260-70. doi: 10.1093/jee/tov081. [PMID: 26470254]
  • Mario Schumann, Anant Patel, Marina Vemmer, Stefan Vidal. The role of carbon dioxide as an orientation cue for western corn rootworm larvae within the maize root system: implications for an attract-and-kill approach. Pest management science. 2014 Apr; 70(4):642-50. doi: 10.1002/ps.3602. [PMID: 23821604]
  • Bingjun He, David M Soderlund. Differential state-dependent modification of rat Na(v)1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin. Toxicology and applied pharmacology. 2011 Dec; 257(3):377-87. doi: 10.1016/j.taap.2011.09.021. [PMID: 21983428]
  • Bingjun He, David M Soderlund. Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Na v 1.7 sodium channels. Neuroscience letters. 2010 Jan; 469(2):268-72. doi: 10.1016/j.neulet.2009.12.012. [PMID: 20006571]