Hexuronic acid (BioDeep_00000840547)

   

PANOMIX_OTCML-2023


代谢物信息卡片


D-Galacturonic acid

化学式: C6H10O7 (194.0427)
中文名称: D(+)-葡萄糖醛酸C, 聚半乳糖醛酸
谱图信息: 最多检出来源 Anoectochilus roxburghii(viridiplantae) 33.33%

分子结构信息

SMILES: C1(C(C(OC(C1O)O)C(=O)O)O)O
InChI: InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)

描述信息

同义名列表

3 个代谢物同义名

D-Galacturonic acid; 6-METHYLDIOSGENIN; Hexuronic acid



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CAT, ELANE, GCK, KHK, VEGFA
Peripheral membrane protein 2 AP1S2, GCK
Nucleus 4 GCK, HPSE, MPO, VEGFA
cytosol 7 AP1S2, ARAF, CAT, ELANE, GCK, HEXA, KHK
phagocytic vesicle 1 ELANE
nucleoplasm 3 GCK, HPSE, MPO
Cell membrane 1 TNF
Cytoplasmic side 1 AP1S2
Golgi apparatus membrane 2 GCK, GLCE
Synapse 2 ACAN, VCAN
cell surface 3 ELANE, TNF, VEGFA
glutamatergic synapse 1 ACAN
Golgi apparatus 4 AP1S2, GLCE, HS6ST2, VEGFA
Golgi membrane 6 AP1S2, GCK, GLCE, HS6ST1, HS6ST2, INS
lysosomal membrane 2 AP1S2, HPSE
neuronal cell body 1 TNF
Lysosome 4 GALNS, HEXA, HPSE, MPO
plasma membrane 3 F2, HS6ST1, TNF
Membrane 7 CAT, HEXA, HPSE, HS6ST1, HS6ST2, VCAN, VEGFA
basolateral plasma membrane 1 GCK
extracellular exosome 7 CAT, ELANE, F2, GALNS, HEXA, KHK, MPO
endoplasmic reticulum 1 VEGFA
extracellular space 10 ACAN, DCN, ELANE, F2, HPSE, INS, MPO, TNF, VCAN, VEGFA
lysosomal lumen 6 ACAN, DCN, GALNS, HEXA, HPSE, VCAN
adherens junction 1 VEGFA
mitochondrion 3 ARAF, CAT, GCK
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 5 AP1S2, CAT, HEXA, HPSE, MPO
Secreted 6 DCN, F2, HPSE, INS, VCAN, VEGFA
extracellular region 12 ACAN, CAT, DCN, ELANE, F2, GALNS, HPSE, INS, MPO, TNF, VCAN, VEGFA
mitochondrial matrix 1 CAT
photoreceptor outer segment 1 VCAN
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 4 ACAN, DCN, VCAN, VEGFA
Early endosome 1 AP1S2
Membrane, clathrin-coated pit 1 AP1S2
clathrin-coated pit 1 AP1S2
recycling endosome 1 TNF
Single-pass type II membrane protein 4 GLCE, HS6ST1, HS6ST2, TNF
Membrane raft 2 HPSE, TNF
focal adhesion 1 CAT
GABA-ergic synapse 1 ACAN
extracellular matrix 3 HPSE, VCAN, VEGFA
Peroxisome 1 CAT
basement membrane 1 ACAN
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 5 ACAN, DCN, ELANE, F2, VCAN
secretory granule 3 ELANE, MPO, VEGFA
phagocytic cup 1 TNF
Cell projection, cilium, photoreceptor outer segment 1 VCAN
blood microparticle 1 F2
Basolateral cell membrane 1 GCK
Endomembrane system 1 AP1S2
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 AP1S2
azurophil granule 2 HEXA, MPO
trans-Golgi network membrane 1 AP1S2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 5 ACAN, DCN, F2, INS, VCAN
endoplasmic reticulum lumen 3 F2, INS, VCAN
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 VEGFA
specific granule lumen 2 ELANE, HPSE
transport vesicle 1 INS
azurophil granule lumen 3 ELANE, GALNS, MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
perineuronal net 2 ACAN, VCAN
phagocytic vesicle lumen 1 MPO
AP-type membrane coat adaptor complex 1 AP1S2
membrane coat 1 AP1S2
AP-1 adaptor complex 1 AP1S2
Cytoplasmic vesicle, phagosome 1 ELANE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
beta-N-acetylhexosaminidase complex 1 HEXA
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix 1 VCAN
interphotoreceptor matrix 1 VCAN
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
perisynaptic extracellular matrix 1 ACAN
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • William J Nicolas, Florian Fäßler, Przemysław Dutka, Florian K M Schur, Grant Jensen, Elliot Meyerowitz. Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks. Current biology : CB. 2022 Jun; 32(11):2375-2389.e6. doi: 10.1016/j.cub.2022.04.024. [PMID: 35508170]
  • Juan Du, Charles T Anderson, Chaowen Xiao. Dynamics of pectic homogalacturonan in cellular morphogenesis and adhesion, wall integrity sensing and plant development. Nature plants. 2022 04; 8(4):332-340. doi: 10.1038/s41477-022-01120-2. [PMID: 35411046]
  • Yuanyuan Zhao, Jinfeng Bi, Jianyong Yi, Xinye Wu, Youchuan Ma, Ruiping Li. Pectin and homogalacturonan with small molecular mass modulate microbial community and generate high SCFAs via in vitro gut fermentation. Carbohydrate polymers. 2021 Oct; 269(?):118326. doi: 10.1016/j.carbpol.2021.118326. [PMID: 34294338]
  • Jianjun Wu, Yongbin Xu, Juan Su, Bo Zhu, Siqi Wang, Kaohua Liu, Huijun Wang, Songshan Shi, Qiaoyan Zhang, Luping Qin, Shunchun Wang. Roles of gut microbiota and metabolites in a homogalacturonan-type pectic polysaccharide from Ficus pumila Linn. fruits mediated amelioration of obesity. Carbohydrate polymers. 2020 Nov; 248(?):116780. doi: 10.1016/j.carbpol.2020.116780. [PMID: 32919569]
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  • Meihua Miao, Xiaozhong Li, Qin Wang, Yunfen Zhu, Yanyan Cui, Xuejun Shao. Association between anti-α-1,4-D-polygalacturonic acid antibodies and Henoch-Schönlein purpura in children. The Journal of international medical research. 2019 Jun; 47(6):2545-2554. doi: 10.1177/0300060519843728. [PMID: 31068035]
  • Meng Wang, Zongchang Xu, Rana Imtiaz Ahmed, Yiping Wang, Ruibo Hu, Gongke Zhou, Yingzhen Kong. Tubby-like Protein 2 regulates homogalacturonan biosynthesis in Arabidopsis seed coat mucilage. Plant molecular biology. 2019 Mar; 99(4-5):421-436. doi: 10.1007/s11103-019-00827-9. [PMID: 30707395]
  • Pengfei Wang, Xinshi Chen, Cameron Goldbeck, Eric Chung, Byung-Ho Kang. A distinct class of vesicles derived from the trans-Golgi mediates secretion of xylogalacturonan in the root border cell. The Plant journal : for cell and molecular biology. 2017 Nov; 92(4):596-610. doi: 10.1111/tpj.13704. [PMID: 28865155]
  • Manisha Buriuli, Wasupalli Geeta Kumari, Devendra Verma. Evaluation of hemostatic effect of polyelectrolyte complex-based dressings. Journal of biomaterials applications. 2017 Nov; 32(5):638-647. doi: 10.1177/0885328217735956. [PMID: 28990448]
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