Ethidium (BioDeep_00000840397)
代谢物信息卡片
Ethidium
化学式: C21H20N3+ (314.1657)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N
InChI: InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:42478
- PubChem: 3624
- ChEMBL: CHEMBL284328
- ChEMBL: CHEMBL48166
- MeSH: Ethidium
- CAS: 3546-21-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Anika, Shamsher Singh, Rimpi. Neuroprotective effects of Embelin in an ethidium bromide-induced multiple sclerosis in rats: Modulation of p38 MAPK signaling pathway.
International immunopharmacology.
2024 Mar; 129(?):111639. doi:
10.1016/j.intimp.2024.111639. [PMID: 38335654] - Manish Kumar Gupta, Sanjana Senthilkumar, Latha Rangan. 3, 5-Dihydroxy 4', 7-dimethoxyflavone-DNA interaction study for nucleic acid detection and differential cell staining.
International journal of biological macromolecules.
2024 Mar; 261(Pt 1):129713. doi:
10.1016/j.ijbiomac.2024.129713. [PMID: 38281518] - Payel Paul, Sarita Sarkar, Debabrata Ghosh Dastidar, Aditya Shukla, Sharmistha Das, Sudipta Chatterjee, Poulomi Chakraborty, Prosun Tribedi. 1, 4-naphthoquinone efficiently facilitates the disintegration of pre-existing biofilm of Staphylococcus aureus through eDNA intercalation.
Folia microbiologica.
2023 Dec; 68(6):843-854. doi:
10.1007/s12223-023-01053-z. [PMID: 37142893] - Ying Liu, Rui Zhu, Xinwei Liu, Dengzhou Li, Mengyu Guo, Bing Fei, Yanying Ren, Xiaojuan You, Yongwei Li. Effect of piperine on the inhibitory potential of MexAB-OprM efflux pump and imipenem resistance in carbapenem-resistant Pseudomonas aeruginosa.
Microbial pathogenesis.
2023 Dec; 185(?):106397. doi:
10.1016/j.micpath.2023.106397. [PMID: 37852553] - Dhama Al-Sallami, Amjed Alsultan, Kadhim Hassan Abbas, Simon R Clarke. Evaluation of efflux pump inhibitory activity of some plant extracts and using them as adjuvants to potentiate the inhibitory activity of some antibiotics against Staphylococcus aureus.
Open veterinary journal.
2023 01; 13(1):42-47. doi:
10.5455/ovj.2023.v13.i1.5. [PMID: 36777436] - Ying Li, Honglin Wen, Xizhen Ge. Opposite motion of the Central Helices of efflux pump KmrA is important for its export efficiency.
Microbial pathogenesis.
2022 Jun; 167(?):105570. doi:
10.1016/j.micpath.2022.105570. [PMID: 35550844] - Flóra Jozefíková, Spyros Perontsis, Katarína Koňáriková, Ľubomír Švorc, Milan Mazúr, George Psomas, Ján Moncol. In vitro biological activity of copper(II) complexes with NSAIDs and nicotinamide: Characterization, DNA- and BSA-interaction study and anticancer activity.
Journal of inorganic biochemistry.
2022 03; 228(?):111696. doi:
10.1016/j.jinorgbio.2021.111696. [PMID: 35030390] - Dimitrios N Zisimopoulos, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, Nikolaos T Panagopoulos, Georgios Salahas, Christos D Georgiou. Detection of superoxide radical in all biological systems by Thin Layer Chromatography.
Archives of biochemistry and biophysics.
2022 02; 716(?):109110. doi:
10.1016/j.abb.2021.109110. [PMID: 34958749] - Jonas Nascimento de Sousa, Aylla Beatriz Melo de Oliveira, Andressa Kelly Ferreira, E Silva, Leide Maria Soares de Sousa, Melissa Carvalho França Rocha, José Pinto de, Siqueira Júnior, Glenn William Kaatz, Jackson Roberto Guedes da Silva Almeida, João Sammy Nery de Souza, Humberto Medeiros Barreto. Modulation of the resistance to norfloxacin in Staphylococcus aureus by Bauhinia forficata link.
Natural product research.
2021 Feb; 35(4):681-685. doi:
10.1080/14786419.2019.1590714. [PMID: 30938178] - Ana C J de Araújo, Priscilla R Freitas, Cristina R Dos Santos Barbosa, Débora F Muniz, Jaime Ribeiro-Filho, Saulo R Tintino, José P S Júnior, José M B Filho, Gabriela R de Sousa, Henrique D M Coutinho. Modulation of Drug Resistance by Limonene: Inhibition of Efflux Pumps in Staphylococcus aureus Strains RN-4220 and IS-58.
Current drug metabolism.
2021; 22(2):110-113. doi:
10.2174/1389200221999210104204718. [PMID: 33397229] - Ryan Shaktah, Laura Vardanyan, Elroma David, Alexis Aleman, Dupre Orr, Lawrence A Shaktah, Daniel Tamae, Thomas Minehan. Synthesis and Stereochemical Assignment of Conioidine A: DNA- and HSA-Binding Studies of the Four Diastereomers.
Journal of natural products.
2020 10; 83(10):3191-3198. doi:
10.1021/acs.jnatprod.0c00871. [PMID: 33034450] - Iqubal Singh, Vijay Luxami, Kamaldeep Paul. Synthesis, cytotoxicity, pharmacokinetic profile, binding with DNA and BSA of new imidazo[1,2-a]pyrazine-benzo[d]imidazol-5-yl hybrids.
Scientific reports.
2020 04; 10(1):6534. doi:
10.1038/s41598-020-63605-4. [PMID: 32300169] - Leila Maria de Sousa Andrade, Aylla Beatriz Melo de Oliveira, Antonio Linkoln Alves Borges Leal, Felipe Araújo de Alcântara Oliveira, Ana Lurdes Portela, José de Sousa Lima Neto, José Pinto de Siqueira-Júnior, Glenn William Kaatz, Cláudia Quintino da Rocha, Humberto Medeiros Barreto. Antimicrobial activity and inhibition of the NorA efflux pump of Staphylococcus aureus by extract and isolated compounds from Arrabidaea brachypoda.
Microbial pathogenesis.
2020 Mar; 140(?):103935. doi:
10.1016/j.micpath.2019.103935. [PMID: 31857236] - Debapriya Garabadu, Deepanshu Singh. Ocimum basilicum attenuates ethidium bromide-induced cognitive deficits and pre-frontal cortical neuroinflammation, astrogliosis and mitochondrial dysfunction in rats.
Metabolic brain disease.
2020 03; 35(3):483-495. doi:
10.1007/s11011-020-00536-z. [PMID: 31997265] - Julia Solnier, Liam Martin, Sanjib Bhakta, Franz Bucar. Flavonoids as Novel Efflux Pump Inhibitors and Antimicrobials Against Both Environmental and Pathogenic Intracellular Mycobacterial Species.
Molecules (Basel, Switzerland).
2020 Feb; 25(3):. doi:
10.3390/molecules25030734. [PMID: 32046221] - Zhixiang Zhu, Ran Guo, Yunqian Li, Shanshan Li, Pengfei Tu. Comparison of three analytical methods for superoxide produced by activated immune cells.
Journal of pharmacological and toxicological methods.
2020 Jan; 101(?):106637. doi:
10.1016/j.vascn.2019.106637. [PMID: 31678429] - Wenfen Zhang, Yanhao Zhang, Guangrui Zhang, Jiying Liu, Wuduo Zhao, Wenjing Zhang, Kai Hu, Fuwei Xie, Shusheng Zhang. Facile preparation of a cationic COF functionalized magnetic nanoparticle and its use for the determination of nine hydroxylated polycyclic aromatic hydrocarbons in smokers' urine.
The Analyst.
2019 Oct; 144(19):5829-5841. doi:
10.1039/c9an01188a. [PMID: 31475698] - Venkatesan Srinivasan, Mariadoss Asha Jhonsi, Namasivayam Dhenadhayalan, King-Chuen Lin, Devanesan Arul Ananth, Thilagar Sivasudha, Radhakrishnan Narayanaswamy, Arunkumar Kathiravan. Pyrene-based prospective biomaterial: In vitro bioimaging, protein binding studies and detection of bilirubin and Fe3.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Oct; 221(?):117150. doi:
10.1016/j.saa.2019.117150. [PMID: 31176291] - Ariadni Zianna, George D Geromichalos, Anna Pekou, Antonios G Hatzidimitriou, Evdoxia Coutouli-Argyropoulou, Maria Lalia-Kantouri, Anastasia A Pantazaki, George Psomas. A palladium(II) complex with the Schiff base 4-chloro-2-(N-ethyliminomethyl)-phenol: Synthesis, structural characterization, and in vitro and in silico biological activity studies.
Journal of inorganic biochemistry.
2019 10; 199(?):110792. doi:
10.1016/j.jinorgbio.2019.110792. [PMID: 31365891] - Shohreh Jahani, Meissam Noroozifar, Mozhgan Khorasani-Motlagh, Masoud Torkzadeh-Mahani, Mahboubeh Adeli-Sardou. In vitro cytotoxicity studies of parent and nanoencapsulated Holmium-2,9-dimethyl-1,10-phenanthroline complex toward fish-salmon DNA-binding properties and antibacterial activity.
Journal of biomolecular structure & dynamics.
2019 10; 37(17):4437-4449. doi:
10.1080/07391102.2018.1557077. [PMID: 30526398] - S W C Silva, N B N Monção, B Q Araújo, D D R Arcanjo, J H L Ferreira, J S Lima Neto, A M G L Citó, J P de Siqueira Júnior, G W Kaatz, H M Barreto. Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes.
Letters in applied microbiology.
2019 Jul; 69(1):57-63. doi:
10.1111/lam.13163. [PMID: 31002429] - Zohreh Moradi, Mozhgan Khorasani-Motlagh, Ali Reza Rezvani, Meissam Noroozifar. Electronic and fluorescent studies on the interaction of DNA and BSA with a new ternary praseodymium complex containing 2,9-dimethyl 1,10-phenanthroline and antibacterial activities testing.
Journal of biomolecular structure & dynamics.
2019 Jun; 37(9):2283-2295. doi:
10.1080/07391102.2018.1479657. [PMID: 30035684] - Alessandra Maria Braga Ribeiro, Jonas Nascimento de Sousa, Luciana Muratori Costa, Felipe Araújo de Alcântara Oliveira, Raimunda Cardoso Dos Santos, Aline Suelen Silva Nunes, Wanderson Oliveira da Silva, Paulo Jorge Marques Cordeiro, José de Sousa Lima Neto, José Pinto de Siqueira-Júnior, Glenn William Kaatz, Humberto Medeiros Barreto, Aldeídia Pereira de Oliveira. Antimicrobial activity of Phyllanthus amarus Schumach. & Thonn and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin.
Microbial pathogenesis.
2019 May; 130(?):242-246. doi:
10.1016/j.micpath.2019.03.012. [PMID: 30876871] - Zhaoxia Chen, Qiao Xu, Gangxu Tang, Shuang Liu, Shuxia Xu, Xinfeng Zhang. A facile electrochemical aptasensor for lysozyme detection based on target-induced turn-off of photosensitization.
Biosensors & bioelectronics.
2019 Feb; 126(?):412-417. doi:
10.1016/j.bios.2018.09.074. [PMID: 30471566] - Rie Hosoi, Sota Sato, Miho Shukuri, Yuka Fujii, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Osamu Inoue. A Simple Ex Vivo Semiquantitative Fluorescent Imaging Utilizing Planar Laser Scanner: Detection of Reactive Oxygen Species Generation in Mouse Brain and Kidney.
Molecular imaging.
2019 Jan; 18(?):1536012118820421. doi:
10.1177/1536012118820421. [PMID: 30799681] - Dušan Ćoćić, Snežana Jovanović, Snežana Radisavljević, Jana Korzekwa, Andreas Scheurer, Ralph Puchta, Dejan Baskić, Danijela Todorović, Suzana Popović, Sanja Matić, Biljana Petrović. New monofunctional platinum(II) and palladium(II) complexes: Studies of the nucleophilic substitution reactions, DNA/BSA interaction, and cytotoxic activity.
Journal of inorganic biochemistry.
2018 12; 189(?):91-102. doi:
10.1016/j.jinorgbio.2018.09.005. [PMID: 30243122] - Chun-Lian Zhang, Ya-Xian Liu, Xue-Mei Zhang, Shi Chen, Fang Shen, Ya-Hong Xiong, Wei Liu, Zong-Wan Mao, Xue-Yi Le. Synthesis, characterization, DNA/HSA interactions and in vitro cytotoxic activities of two novel water-soluble copper(II) complexes with 1,3,5-triazine derivative ligand and amino acids.
Materials science & engineering. C, Materials for biological applications.
2018 Oct; 91(?):414-425. doi:
10.1016/j.msec.2018.05.065. [PMID: 30033272] - Debjani P Mansingh, Sunanda O J, Veeresh Kumar Sali, Hannah R Vasanthi. [6]-Gingerol-induced cell cycle arrest, reactive oxygen species generation, and disruption of mitochondrial membrane potential are associated with apoptosis in human gastric cancer (AGS) cells.
Journal of biochemical and molecular toxicology.
2018 Oct; 32(10):e22206. doi:
10.1002/jbt.22206. [PMID: 30091159] - Yifei Zhang, Haojie Shi, Benliang Deng. Mutagen-induced phytotoxicity in maize seed germination is dependent on ROS scavenging capacity.
Scientific reports.
2018 09; 8(1):14078. doi:
10.1038/s41598-018-32271-y. [PMID: 30232360] - Nuriye Akbay, Tugba Taskin Tok, Zeynel Seferoğlu, Elmas Gökoğlu. Investigation of binding properties of two ethidium derivatives with serum albumins: spectral and computational approach.
Journal of biomolecular structure & dynamics.
2018 Sep; 36(12):3114-3121. doi:
10.1080/07391102.2017.1380536. [PMID: 28911252] - Kelvin Agboh, Calvin H F Lau, Yvonne S K Khoo, Himansha Singh, Sagar Raturi, Asha V Nair, Julie Howard, Marco Chiapello, Renata Feret, Michael J Deery, Satoshi Murakami, Hendrik W van Veen. Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force.
Science advances.
2018 09; 4(9):eaas9365. doi:
10.1126/sciadv.aas9365. [PMID: 30255140] - Jitender Kumar Bhardwaj, Priya Kumari, Priyanka Saraf, Abhay Singh Yadav. Antiapoptotic effects of vitamins C and E against cypermethrin-induced oxidative stress and spermatogonial germ cell apoptosis.
Journal of biochemical and molecular toxicology.
2018 Aug; 32(8):e22174. doi:
10.1002/jbt.22174. [PMID: 29975445] - G Kalaiarasi, S Rex Jeya Rajkumar, G Aswini, S Dharani, Frank R Fronczek, R Prabhakaran. 3-Acetyl-8-methoxy-2[H]-chromen-2-one derived Schiff bases as potent antiproliferative agents: Insight into the influence of 4(N)-substituents on the in vitro biological activity.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2018 Jul; 200(?):246-262. doi:
10.1016/j.saa.2018.04.028. [PMID: 29694929] - Joycy F S Dos Santos, Saulo R Tintino, Thiago S de Freitas, Fábia F Campina, Irwin R de A Menezes, José P Siqueira-Júnior, Henrique D M Coutinho, Francisco A B Cunha. In vitro e in silico evaluation of the inhibition of Staphylococcus aureus efflux pumps by caffeic and gallic acid.
Comparative immunology, microbiology and infectious diseases.
2018 Apr; 57(?):22-28. doi:
10.1016/j.cimid.2018.03.001. [PMID: 30017074] - Marie Billaud, Julie A Phillippi, Mary P Kotlarczyk, Jennifer C Hill, Bradley W Ellis, Claudette M St Croix, Nadiezhda Cantu-Medéllin, Eric E Kelley, Thomas G Gleason. Elevated oxidative stress in the aortic media of patients with bicuspid aortic valve.
The Journal of thoracic and cardiovascular surgery.
2017 11; 154(5):1756-1762. doi:
10.1016/j.jtcvs.2017.05.065. [PMID: 28651938] - Alyssa L Margiotta, Lisa J Bain, Charles D Rice. Expression of the Major Vault Protein (MVP) and Cellular Vault Particles in Fish.
Anatomical record (Hoboken, N.J. : 2007).
2017 Nov; 300(11):1981-1992. doi:
10.1002/ar.23645. [PMID: 28710803] - Xi Qiao, Lihua Wang, Yanhong Wang, Xiaole Su, Yue Qi, Yun Fan, Zhiqiang Peng. Intermedin inhibits unilateral ureteral obstruction-induced oxidative stress via NADPH oxidase Nox4 and cAMP-dependent mechanisms.
Renal failure.
2017 Nov; 39(1):652-659. doi:
10.1080/0886022x.2017.1361839. [PMID: 28805491] - Merissa M Bruns, Prathusha Kakarla, Jared T Floyd, Mun Mun Mukherjee, Robert C Ponce, John A Garcia, Indrika Ranaweera, Leslie M Sanford, Alberto J Hernandez, T Mark Willmon, Grace L Tolson, Manuel F Varela. Modulation of the multidrug efflux pump EmrD-3 from Vibrio cholerae by Allium sativum extract and the bioactive agent allyl sulfide plus synergistic enhancement of antimicrobial susceptibility by A. sativum extract.
Archives of microbiology.
2017 Oct; 199(8):1103-1112. doi:
10.1007/s00203-017-1378-x. [PMID: 28432381] - Prathusha Kakarla, Jared Floyd, MunMun Mukherjee, Amith R Devireddy, Madhuri A Inupakutika, Indrika Ranweera, Ranjana Kc, Ugina 'Shrestha, Upender Rao Cheeti, Thomas Mark Willmon, Jaclyn Adams, Merissa Bruns, Shravan Kumar Gunda, Manuel F Varela. Inhibition of the multidrug efflux pump LmrS from Staphylococcus aureus by cumin spice Cuminum cyminum.
Archives of microbiology.
2017 Apr; 199(3):465-474. doi:
10.1007/s00203-016-1314-5. [PMID: 27830269] - Rajan Ramachandran, Chandran Krishnaraj, Allur Subramaniyan Sivakumar, Palaniappan Prasannakumar, V K Abhay Kumar, Kwan Seob Shim, Chul-Gyu Song, Soon-Il Yun. Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish.
Materials science & engineering. C, Materials for biological applications.
2017 Apr; 73(?):674-683. doi:
10.1016/j.msec.2016.12.110. [PMID: 28183660] - Bei Zhang, William M Bailey, Anna Leigh McVicar, John C Gensel. Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury.
Neurobiology of aging.
2016 11; 47(?):157-167. doi:
10.1016/j.neurobiolaging.2016.07.029. [PMID: 27596335] - Legna Colina-Vegas, Jocely Lucena Dutra, Wilmer Villarreal, João Honorato de A Neto, Marcia Regina Cominetti, Fernando Pavan, Maribel Navarro, Alzir A Batista. Ru(II)/clotrimazole/diphenylphosphine/bipyridine complexes: Interaction with DNA, BSA and biological potential against tumor cell lines and Mycobacterium tuberculosis.
Journal of inorganic biochemistry.
2016 09; 162(?):135-145. doi:
10.1016/j.jinorgbio.2016.06.023. [PMID: 27383651] - Spyros Perontsis, Antonios G Hatzidimitriou, Olga-Aggeliki Begou, Athanasios N Papadopoulos, George Psomas. Characterization and biological properties of copper(II)-ketoprofen complexes.
Journal of inorganic biochemistry.
2016 09; 162(?):22-30. doi:
10.1016/j.jinorgbio.2016.06.001. [PMID: 27323214] - Spyros Perontsis, Antonios G Hatzidimitriou, Athanasios N Papadopoulos, George Psomas. Nickel-diflunisal complexes: synthesis, characterization, in vitro antioxidant activity and interaction with DNA and albumins.
Journal of inorganic biochemistry.
2016 09; 162(?):9-21. doi:
10.1016/j.jinorgbio.2016.06.003. [PMID: 27318424] - Himansha Singh, Saroj Velamakanni, Michael J Deery, Julie Howard, Shen L Wei, Hendrik W van Veen. ATP-dependent substrate transport by the ABC transporter MsbA is proton-coupled.
Nature communications.
2016 08; 7(?):12387. doi:
10.1038/ncomms12387. [PMID: 27499013] - Mayumi Yamato, Kimika Kawano, Yuki Yamanaka, Misako Saiga, Ken-Ichi Yamada. TEMPOL increases NAD(+) and improves redox imbalance in obese mice.
Redox biology.
2016 08; 8(?):316-22. doi:
10.1016/j.redox.2016.02.007. [PMID: 26942863] - Theocharis E Kydonaki, Evangelos Tsoukas, Filipa Mendes, Antonios G Hatzidimitriou, António Paulo, Lefkothea C Papadopoulou, Dionysia Papagiannopoulou, George Psomas. Synthesis, characterization and biological evaluation of (99m)Tc/Re-tricarbonyl quinolone complexes.
Journal of inorganic biochemistry.
2016 07; 160(?):94-105. doi:
10.1016/j.jinorgbio.2015.12.010. [PMID: 26795497] - Wei Zhang, Di Yao, Yi Wei, Jie Tang, He-Dong Bian, Fu-Ping Huang, Hong Liang. Synthesis, characterization, DNA/protein interaction and cytotoxicity studies of Cu(II) and Co(II) complexes derived from dipyridyl triazole ligands.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2016 Jun; 163(?):28-44. doi:
10.1016/j.saa.2016.03.010. [PMID: 27043870] - Thanyaluck Siriyong, Sasitorn Chusri, Potjanee Srimanote, Varomyalin Tipmanee, Supayang Piyawan Voravuthikunchai. Holarrhena antidysenterica Extract and Its Steroidal Alkaloid, Conessine, as Resistance-Modifying Agents Against Extensively Drug-Resistant Acinetobacter baumannii.
Microbial drug resistance (Larchmont, N.Y.).
2016 Jun; 22(4):273-82. doi:
10.1089/mdr.2015.0194. [PMID: 26745443] - Yi Yu, Yuyan Xiong, Jean-Pierre Montani, Zhihong Yang, Xiu-Fen Ming. En Face Detection of Nitric Oxide and Superoxide in Endothelial Layer of Intact Arteries.
Journal of visualized experiments : JoVE.
2016 Feb; ?(108):53718. doi:
10.3791/53718. [PMID: 26967197] - Marcondes Alves B Silva, Stefany Bruno A Cau, Rheure Alves M Lopes, Carla P Manzato, Karla B Neves, Thiago Bruder-Nascimento, Fabiola Leslie Antunes C Mestriner, Augusto C Montezano, Aurelie Nguyen Dinh Cat, Rhian M Touyz, Rita C Tostes. Mineralocorticoid receptor blockade prevents vascular remodelling in a rodent model of type 2 diabetes mellitus.
Clinical science (London, England : 1979).
2015 Oct; 129(7):533-45. doi:
10.1042/cs20140758. [PMID: 25967696] - Christian Bellehumeur, Brian Boyle, Steve J Charette, Josée Harel, Yvan L'Homme, Luke Masson, Carl A Gagnon. Propidium monoazide (PMA) and ethidium bromide monoazide (EMA) improve DNA array and high-throughput sequencing of porcine reproductive and respiratory syndrome virus identification.
Journal of virological methods.
2015 Sep; 222(?):182-91. doi:
10.1016/j.jviromet.2015.06.014. [PMID: 26129867] - Jaideep B Bharate, Samsher Singh, Abubakar Wani, Sadhana Sharma, Prashant Joshi, Inshad A Khan, Ajay Kumar, Ram A Vishwakarma, Sandip B Bharate. Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump.
Organic & biomolecular chemistry.
2015 May; 13(19):5424-31. doi:
10.1039/c5ob00246j. [PMID: 25865846] - Plamena R Angelova, Mathew H Horrocks, David Klenerman, Sonia Gandhi, Andrey Y Abramov, Mikhail S Shchepinov. Lipid peroxidation is essential for α-synuclein-induced cell death.
Journal of neurochemistry.
2015 May; 133(4):582-9. doi:
10.1111/jnc.13024. [PMID: 25580849] - Lin Bi, Yuan-Hua Yu. Phosphorescent quantum dots/ethidium bromide nanohybrids based on photoinduced electron transfer for DNA detection.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2015 Apr; 140(?):479-83. doi:
10.1016/j.saa.2015.01.014. [PMID: 25638430] - Fabiano B Carvalho, Jessié M Gutierres, Crystiani Bohnert, Adriana M Zago, Fátima H Abdalla, Juliano M Vieira, Heloisa E Palma, Sara M Oliveira, Roselia M Spanevello, Marta M Duarte, Sonia T A Lopes, Graciane Aiello, Marta G Amaral, Ney Luis Pippi, Cinthia M Andrade. Anthocyanins suppress the secretion of proinflammatory mediators and oxidative stress, and restore ion pump activities in demyelination.
The Journal of nutritional biochemistry.
2015 Apr; 26(4):378-90. doi:
10.1016/j.jnutbio.2014.11.006. [PMID: 25632845] - Cangman Zhang, Biao Ren, Zongtao Lin, Lingkun Tong, Hong Wang, Shizhong Chen. An analysis method for simultaneous screening of deoxyribonucleic acid-binding active compounds and investigating their mechanisms by ultra-fast liquid chromatography tandem mass spectrometry coupled with fluorescence detection technology.
Journal of chromatography. A.
2015 Feb; 1381(?):160-72. doi:
10.1016/j.chroma.2015.01.019. [PMID: 25616969] - Kathrin Bellmann-Sickert, Tracy A Stone, Bradley E Poulsen, Charles M Deber. Efflux by small multidrug resistance proteins is inhibited by membrane-interactive helix-stapled peptides.
The Journal of biological chemistry.
2015 Jan; 290(3):1752-9. doi:
10.1074/jbc.m114.616185. [PMID: 25425644] - Elena Ogalla, Carmen Claro, María Alvarez de Sotomayor, Maria Dolores Herrera, Rosalia Rodriguez-Rodriguez. Structural, mechanical and myogenic properties of small mesenteric arteries from ApoE KO mice: characterization and effects of virgin olive oil diets.
Atherosclerosis.
2015 Jan; 238(1):55-63. doi:
10.1016/j.atherosclerosis.2014.11.022. [PMID: 25437891] - Adam R Brown, Keivan A Ettefagh, Daniel Todd, Patrick S Cole, Joseph M Egan, Daniel H Foil, Tyler N Graf, Bryan D Schindler, Glenn W Kaatz, Nadja B Cech. A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition.
PloS one.
2015; 10(5):e0124814. doi:
10.1371/journal.pone.0124814. [PMID: 25961825] - Monika Mishra, Karishma Tiwari, Sachin Shukla, R Mishra, Vinod P Singh. Synthesis, structural investigation, DNA and protein binding study of some 3d-metal complexes with N'-(phenyl-pyridin-2-yl-methylene)-thiophene-2-carboxylic acid hydrazide.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Nov; 132(?):452-64. doi:
10.1016/j.saa.2014.05.007. [PMID: 24892525] - Ryan L O'Hare Doig, Carole A Bartlett, Ghassan J Maghzal, Magdalena Lam, Michael Archer, Roland Stocker, Melinda Fitzgerald. Reactive species and oxidative stress in optic nerve vulnerable to secondary degeneration.
Experimental neurology.
2014 Nov; 261(?):136-46. doi:
10.1016/j.expneurol.2014.06.007. [PMID: 24931225] - S Farooq, A-T- Wahab, C D A Fozing, A-U- Rahman, M Iqbal Choudhary. Artonin I inhibits multidrug resistance in Staphylococcus aureus and potentiates the action of inactive antibiotics in vitro.
Journal of applied microbiology.
2014 Oct; 117(4):996-1011. doi:
10.1111/jam.12595. [PMID: 24996035] - Rajpal Sharma, Daniel Nisakar, Shivangi Shivpuri, Munia Ganguli. Contrasting effects of cysteine modification on the transfection efficiency of amphipathic peptides.
Biomaterials.
2014 Aug; 35(24):6563-75. doi:
10.1016/j.biomaterials.2014.04.046. [PMID: 24816284] - Diego V Beckmann, Fabiano B Carvalho, Cinthia M Mazzanti, Rosmarini P Dos Santos, Amanda O Andrades, Graciane Aiello, Angel Rippilinger, Dominguita L Graça, Fátima H Abdalla, Lizielle S Oliveira, Jessié M Gutierres, Maria Rosa C Schetinger, Alexandre Mazzanti. Neuroprotective role of quercetin in locomotor activities and cholinergic neurotransmission in rats experimentally demyelinated with ethidium bromide.
Life sciences.
2014 May; 103(2):79-87. doi:
10.1016/j.lfs.2014.03.033. [PMID: 24727240] - Xia-Bing Fu, Zi-Hua Lin, Hai-Feng Liu, Xue-Yi Le. A new ternary copper(II) complex derived from 2-(2'-pyridyl)benzimidazole and glycylglycine: synthesis, characterization, DNA binding and cleavage, antioxidation and HSA interaction.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Mar; 122(?):22-33. doi:
10.1016/j.saa.2013.11.006. [PMID: 24291450] - Marianthi Zampakou, Natalia Rizeq, Vassilis Tangoulis, Athanasios N Papadopoulos, Franc Perdih, Iztok Turel, George Psomas. Manganese(II) complexes with the non-steroidal anti-inflammatory drug tolfenamic acid: structure and biological perspectives.
Inorganic chemistry.
2014 Feb; 53(4):2040-52. doi:
10.1021/ic4025487. [PMID: 24467343] - Rajnikant Sharma, Sankalp Arya, Supriya Deepak Patil, Atin Sharma, Pradeep Kumar Jain, Naveen Kumar Navani, Ranjana Pathania. Identification of novel regulatory small RNAs in Acinetobacter baumannii.
PloS one.
2014; 9(4):e93833. doi:
10.1371/journal.pone.0093833. [PMID: 24705412] - Alexander Hahn, Mara Stevanovic, Oliver Mirus, Iryna Lytvynenko, Klaas Martinus Pos, Enrico Schleiff. The outer membrane TolC-like channel HgdD is part of tripartite resistance-nodulation-cell division (RND) efflux systems conferring multiple-drug resistance in the Cyanobacterium Anabaena sp. PCC7120.
The Journal of biological chemistry.
2013 Oct; 288(43):31192-205. doi:
10.1074/jbc.m113.495598. [PMID: 24014018] - Jakob Kljun, Ioannis Bratsos, Enzo Alessio, George Psomas, Urška Repnik, Miha Butinar, Boris Turk, Iztok Turel. New uses for old drugs: attempts to convert quinolone antibacterials into potential anticancer agents containing ruthenium.
Inorganic chemistry.
2013 Aug; 52(15):9039-52. doi:
10.1021/ic401220x. [PMID: 23886077] - Rupak Doshi, Hendrik W van Veen. Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA.
The Journal of biological chemistry.
2013 Jul; 288(30):21638-47. doi:
10.1074/jbc.m113.485714. [PMID: 23766512] - M Abu Mraheil, A Heisig, P Heisig. An improved assay for the detection of alterations in bacterial DNA supercoiling in vivo.
Die Pharmazie.
2013 Jul; 68(7):541-8. doi:
". [PMID: 23923635] - Qin-Fang Zhang, Wen-Jing Yi, Bing Wang, Ji Zhang, Laifeng Ren, Qian-Ming Chen, Liandi Guo, Xiao-Qi Yu. Linear polycations by ring-opening polymerization as non-viral gene delivery vectors.
Biomaterials.
2013 Jul; 34(21):5391-401. doi:
10.1016/j.biomaterials.2013.03.083. [PMID: 23582685] - Marianthi Zampakou, Melpomeni Akrivou, Eleni G Andreadou, Catherine P Raptopoulou, Vassilis Psycharis, Anastasia A Pantazaki, George Psomas. Structure, antimicrobial activity, DNA- and albumin-binding of manganese(II) complexes with the quinolone antimicrobial agents oxolinic acid and enrofloxacin.
Journal of inorganic biochemistry.
2013 Apr; 121(?):88-99. doi:
10.1016/j.jinorgbio.2012.12.013. [PMID: 23353085] - Zhiling Song, Hong Wang, Biao Ren, Baobao Zhang, Yuki Hashi, Shizhong Chen. On-line study of flavonoids of Trollius chinensis Bunge binding to DNA with ethidium bromide using a novel combination of chromatographic, mass spectrometric and fluorescence techniques.
Journal of chromatography. A.
2013 Mar; 1282(?):102-12. doi:
10.1016/j.chroma.2013.01.060. [PMID: 23411144] - R J Aitken, T B Smith, T Lord, L Kuczera, A J Koppers, N Naumovski, H Connaughton, M A Baker, G N De Iuliis. On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid.
Andrology.
2013 Mar; 1(2):192-205. doi:
10.1111/j.2047-2927.2012.00056.x. [PMID: 23316012] - Anna Byczkowska, Anita Kunikowska, Andrzej Kaźmierczak. Determination of ACC-induced cell-programmed death in roots of Vicia faba ssp. minor seedlings by acridine orange and ethidium bromide staining.
Protoplasma.
2013 Feb; 250(1):121-8. doi:
10.1007/s00709-012-0383-9. [PMID: 22350735] - Jun-Jie Koh, Shengxiang Qiu, Hanxun Zou, Rajamani Lakshminarayanan, Jianguo Li, Xiaojun Zhou, Charles Tang, Padmanabhan Saraswathi, Chandra Verma, Donald T H Tan, Ai Ling Tan, Shouping Liu, Roger W Beuerman. Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting.
Biochimica et biophysica acta.
2013 Feb; 1828(2):834-44. doi:
10.1016/j.bbamem.2012.09.004. [PMID: 22982495] - Adriana M Ojeda-Sana, Victoria Repetto, Silvia Moreno. Carnosic acid is an efflux pumps modulator by dissipation of the membrane potential in Enterococcus faecalis and Staphylococcus aureus.
World journal of microbiology & biotechnology.
2013 Jan; 29(1):137-44. doi:
10.1007/s11274-012-1166-3. [PMID: 22961443] - Yuji Ishibashi, Takanori Matsui, Keisuke Ohta, Ryuichiro Tanoue, Masayoshi Takeuchi, Katsuhiko Asanuma, Kei Fukami, Seiya Okuda, Kei-ichiro Nakamura, Sho-ichi Yamagishi. PEDF inhibits AGE-induced podocyte apoptosis via PPAR-gamma activation.
Microvascular research.
2013 Jan; 85(?):54-8. doi:
10.1016/j.mvr.2012.10.007. [PMID: 23108227] - María Del Carmen García-Rodríguez, Megumi Monserrat Carvente-Juárez, Mario Agustín Altamirano-Lozano. Antigenotoxic and apoptotic activity of green tea polyphenol extracts on hexavalent chromium-induced DNA damage in peripheral blood of CD-1 mice: analysis with differential acridine orange/ethidium bromide staining.
Oxidative medicine and cellular longevity.
2013; 2013(?):486419. doi:
10.1155/2013/486419. [PMID: 24363823] - Shagun Arora, Shristhi Goyal, Jay Balani, Simran Tandon. Enhanced antiproliferative effects of aqueous extracts of some medicinal mushrooms on colon cancer cells.
International journal of medicinal mushrooms.
2013; 15(3):301-14. doi:
10.1615/intjmedmushr.v15.i3.70. [PMID: 23662617] - Valentina Gallo, Oleksii A Skorokhod, Evelin Schwarzer, Paolo Arese. Simultaneous determination of phagocytosis of Plasmodium falciparum-parasitized and non-parasitized red blood cells by flow cytometry.
Malaria journal.
2012 Dec; 11(?):428. doi:
10.1186/1475-2875-11-428. [PMID: 23259636] - Felix Distelmaier, Federica Valsecchi, Marleen Forkink, Sjenet van Emst-de Vries, Herman G Swarts, Richard J T Rodenburg, Eugène T P Verwiel, Jan A M Smeitink, Peter H G M Willems, Werner J H Koopman. Trolox-sensitive reactive oxygen species regulate mitochondrial morphology, oxidative phosphorylation and cytosolic calcium handling in healthy cells.
Antioxidants & redox signaling.
2012 Dec; 17(12):1657-69. doi:
10.1089/ars.2011.4294. [PMID: 22559215] - Kazuki Noda, Maki Hosoya, Sota Nakajima, Junko Ohashi, Yoshihiro Fukumoto, Hiroaki Shimokawa. Anti-atherogenic effects of the combination therapy with olmesartan and azelnidipine in diabetic apolipoprotein E-deficient mice.
The Tohoku journal of experimental medicine.
2012 12; 228(4):305-15. doi:
10.1620/tjem.228.305. [PMID: 23124103] - Petra Živec, Franc Perdih, Iztok Turel, Gerald Giester, George Psomas. Different types of copper complexes with the quinolone antimicrobial drugs ofloxacin and norfloxacin: structure, DNA- and albumin-binding.
Journal of inorganic biochemistry.
2012 Dec; 117(?):35-47. doi:
10.1016/j.jinorgbio.2012.08.008. [PMID: 23078773] - G M Pires-Santos, K G Santana-Anjos, M A Vannier-Santos. Optimization of Entamoeba histolytica culturing in vitro.
Experimental parasitology.
2012 Dec; 132(4):561-5. doi:
10.1016/j.exppara.2012.09.011. [PMID: 23026453] - Alexander Hahn, Mara Stevanovic, Oliver Mirus, Enrico Schleiff. The TolC-like protein HgdD of the cyanobacterium Anabaena sp. PCC 7120 is involved in secondary metabolite export and antibiotic resistance.
The Journal of biological chemistry.
2012 Nov; 287(49):41126-38. doi:
10.1074/jbc.m112.396010. [PMID: 23071120] - Eswaran Ramachandran, Duraisamy Senthil Raja, Nattamai S P Bhuvanesh, Karuppannan Natarajan. Mixed ligand palladium(II) complexes of 6-methoxy-2-oxo-1,2-dihydroquinoline-3-carbaldehyde 4N-substituted thiosemicarbazones with triphenylphosphine co-ligand: synthesis, crystal structure and biological properties.
Dalton transactions (Cambridge, England : 2003).
2012 Nov; 41(43):13308-23. doi:
10.1039/c2dt31079a. [PMID: 22864662] - Shalini Minocha, Russell J Mumper. Effect of carbon coating on the physico-chemical properties and toxicity of copper and nickel nanoparticles.
Small (Weinheim an der Bergstrasse, Germany).
2012 Nov; 8(21):3289-99. doi:
10.1002/smll.201200478. [PMID: 22837153] - Simone Pereira-Simon, Xiaomei Xia, Paola Catanuto, Sharon Elliot. Oxidant stress and mitochondrial signaling regulate reversible changes of ERα expression and apoptosis in aging mouse glomeruli and mesangial cells.
Endocrinology.
2012 Nov; 153(11):5491-9. doi:
10.1210/en.2012-1379. [PMID: 23027807] - Illkyu-O Lee, Mario T Kratz, Stephan H Schirmer, Magnus Baumhäkel, Michael Böhm. The effects of direct thrombin inhibition with dabigatran on plaque formation and endothelial function in apolipoprotein E-deficient mice.
The Journal of pharmacology and experimental therapeutics.
2012 Nov; 343(2):253-7. doi:
10.1124/jpet.112.194837. [PMID: 22837011] - Vivian Soetikno, Flori R Sari, Vijayakumar Sukumaran, Arun Prasath Lakshmanan, Sayaka Mito, Meilei Harima, Rajarajan A Thandavarayan, Kenji Suzuki, Masaki Nagata, Ritsuo Takagi, Kenichi Watanabe. Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2012 Oct; 47(3):604-14. doi:
10.1016/j.ejps.2012.04.018. [PMID: 22564708] - Sudipta Nandi, Parimal Routh, Rama K Layek, Arun K Nandi. Ethidium bromide-adsorbed graphene templates as a platform for preferential sensing of DNA.
Biomacromolecules.
2012 Oct; 13(10):3181-8. doi:
10.1021/bm3009632. [PMID: 22984813] - Somendu K Roy, Sonika Pahwa, Hemraj Nandanwar, Sanjay M Jachak. Phenylpropanoids of Alpinia galanga as efflux pump inhibitors in Mycobacterium smegmatis mc² 155.
Fitoterapia.
2012 Oct; 83(7):1248-55. doi:
10.1016/j.fitote.2012.06.008. [PMID: 22735598] - Z Kaderjakova, I Lajdova, M Horvathova, M Morvova, L Sikurova. Effects of chronic kidney disease on blood cells membrane properties.
Bioelectrochemistry (Amsterdam, Netherlands).
2012 Oct; 87(?):226-9. doi:
10.1016/j.bioelechem.2012.02.006. [PMID: 22425286] - Hari Hendarto, Toyoshi Inoguchi, Yasutaka Maeda, Noriko Ikeda, Jing Zheng, Ryoko Takei, Hisashi Yokomizo, Eiichi Hirata, Noriyuki Sonoda, Ryoichi Takayanagi. GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases.
Metabolism: clinical and experimental.
2012 Oct; 61(10):1422-34. doi:
10.1016/j.metabol.2012.03.002. [PMID: 22554832] - Hamish S Sutherland, In Young Hwang, Elaine S Marshall, Brent S Lindsay, William A Denny, Catherine Gilchrist, Wayne R Joseph, Debra Greenhalgh, Emma Richardson, Philip Kestell, Angela Ding, Bruce C Baguley. Therapeutic reactivation of mutant p53 protein by quinazoline derivatives.
Investigational new drugs.
2012 Oct; 30(5):2035-45. doi:
10.1007/s10637-011-9744-z. [PMID: 21912889] - Isabelle Passagne, Marie Morille, Marine Rousset, Igor Pujalté, Béatrice L'azou. Implication of oxidative stress in size-dependent toxicity of silica nanoparticles in kidney cells.
Toxicology.
2012 Sep; 299(2-3):112-24. doi:
10.1016/j.tox.2012.05.010. [PMID: 22627296]
