deoxymannojirimycin (BioDeep_00000007903)
natural product
代谢物信息卡片
化学式: C6H13NO4 (163.0845)
中文名称: 盐酸脱氧甘露霉素
谱图信息:
最多检出来源 Homo sapiens(not specific) 50%
分子结构信息
SMILES: C1C(C(C(C(N1)CO)O)O)O
InChI: InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
描述信息
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D004791 - Enzyme Inhibitors
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- KEGG: C10141
- PubChem: 72258
- DrugBank: DB03955
- ChEMBL: CHEMBL84844
- MeSH: 1-Deoxynojirimycin
- KNApSAcK: C00002035
- CAS: 84444-90-6
- PMhub: MS000021416
- PubChem: 12327
- PDB-CCD: DMJ
- 3DMET: B03579
- NIKKAJI: J227.975D
- RefMet: Deoxymannojirimycin
- LOTUS: LTS0245637
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
39 个相关的物种来源信息
- 82270 - Adenophora: LTS0245637
- 187269 - Adenophora triphylla: 10.1016/S0031-9422(99)00555-5
- 187269 - Adenophora triphylla: LTS0245637
- 265775 - Adenophora triphylla var. japonica: 10.1016/S0031-9422(99)00555-5
- 265775 - Adenophora triphylla var. japonica: LTS0245637
- 357 - Agrobacterium: 10.7164/ANTIBIOTICS.42.1302
- 357 - Agrobacterium: LTS0245637
- 28211 - Alphaproteobacteria: LTS0245637
- 53826 - Angylocalyx: LTS0245637
- 149630 - Angylocalyx pynaertii:
- 149630 - Angylocalyx pynaertii: 10.1021/NP010360F
- 149630 - Angylocalyx pynaertii: 10.1021/NP50098A020
- 149630 - Angylocalyx pynaertii: 10.1046/J.1432-1327.2001.01837.X
- 149630 - Angylocalyx pynaertii: LTS0245637
- 6656 - Arthropoda: LTS0245637
- 2 - Bacteria: LTS0245637
- 4381 - Campanulaceae: LTS0245637
- 4743 - Commelina: LTS0245637
- 4744 - Commelina communis: 10.1055/S-2006-960803
- 4744 - Commelina communis: LTS0245637
- 4740 - Commelinaceae: LTS0245637
- 2759 - Eukaryota: LTS0245637
- 3977 - Euphorbiaceae: LTS0245637
- 3803 - Fabaceae: LTS0245637
- 50557 - Insecta: LTS0245637
- 4447 - Liliopsida: LTS0245637
- 3925 - Lonchocarpus: LTS0245637
- 1225672 - Lonchocarpus sericeus: 10.1016/S0031-9422(00)86981-2
- 1225672 - Lonchocarpus sericeus: LTS0245637
- 3398 - Magnoliopsida: LTS0245637
- 289648 - Omphalea: LTS0245637
- 289649 - Omphalea diandra: 10.1002/(SICI)1099-1565(199909/10)10:5<259::AID-PCA463>3.0.CO;2-8
- 289649 - Omphalea diandra: LTS0245637
- 82115 - Rhizobiaceae: LTS0245637
- 379 - Rhizobium: 10.7164/ANTIBIOTICS.42.1302
- 379 - Rhizobium: LTS0245637
- 35493 - Streptophyta: LTS0245637
- 58023 - Tracheophyta: LTS0245637
- 33090 - Viridiplantae: LTS0245637
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Jose A Villalobos, Rebecca E Cahoon, Edgar B Cahoon, Ian S Wallace. Glucosylceramides impact cellulose deposition and cellulose synthase complex motility in Arabidopsis.
Glycobiology.
2024 Apr; 34(6):. doi:
10.1093/glycob/cwae035
. [PMID: 38690785] - Varun Jaiswal, Mi-Jin Lee, Ju Lan Chun, Miey Park, Hae-Jeung Lee. 1-Deoxynojirimycin containing Morus alba leaf-based food modulates the gut microbiome and expression of genes related to obesity.
BMC veterinary research.
2024 Apr; 20(1):133. doi:
10.1186/s12917-024-03961-9
. [PMID: 38570815] - Yangzhen Liao, Wenmin Du, Jingqiong Wan, Jiahe Fan, Jilan Pi, Min Wu, Yuan Wei, Zhen Ouyang. Mining and functional characterization of NADPH-cytochrome P450 reductases of the DNJ biosynthetic pathway in mulberry leaves.
BMC plant biology.
2024 Feb; 24(1):133. doi:
10.1186/s12870-024-04815-0
. [PMID: 38395770] - Lucia Marchetti, Eleonora Truzzi, Maria Cecilia Rossi, Stefania Benvenuti, Silvia Cappellozza, Alessio Saviane, Luca Bogataj, Cristina Siligardi, Davide Bertelli. Alginate-Based Carriers Loaded with Mulberry (Morus alba L.) Leaf Extract: A Promising Strategy for Prolonging 1-Deoxynojirimicyn (DNJ) Systemic Activity for the Nutraceutical Management of Hyperglycemic Conditions.
Molecules (Basel, Switzerland).
2024 Feb; 29(4):. doi:
10.3390/molecules29040797
. [PMID: 38398549] - Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-Yan Du, Yan Jiang. Mulberry leaf multi-components exert hypoglycemic effects through regulation of the PI-3K/Akt insulin signaling pathway in type 2 diabetic rats.
Journal of ethnopharmacology.
2024 Jan; 319(Pt 3):117307. doi:
10.1016/j.jep.2023.117307
. [PMID: 37939911] - Saniye Karabudak, Vildan Güzel, Beril Güler, Bülent Uyanık, Azize Esra Gürsoy. A case report of Tangier disease presents with acute sensorimotor polyneuropathy and its treatment approach.
Journal of clinical lipidology.
2023 Dec; ?(?):. doi:
10.1016/j.jacl.2023.11.015
. [PMID: 38172008] - Xinxiu Ren, Qinfeng Guo, Hui Jiang, Xiao Han, Xiaoshi He, Haodong Liu, Zhilong Xiu, Yuesheng Dong. Combinational application of the natural products 1-deoxynojirimycin and morin ameliorates insulin resistance and lipid accumulation in prediabetic mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Sep; 121(?):155106. doi:
10.1016/j.phymed.2023.155106
. [PMID: 37797432] - Cécile Freihuber, Bahia Dahmani-Rabehi, Anaïs Brassier, Pierre Broué, Claude Cances, Brigitte Chabrol, Didier Eyer, François Labarthe, Philippe Latour, Thierry Levade, Samia Pichard, Caroline Sevin, Marie T Vanier, Bénédicte Héron. Effects of miglustat therapy on neurological disorder and survival in early-infantile Niemann-Pick disease type C: a national French retrospective study.
Orphanet journal of rare diseases.
2023 07; 18(1):204. doi:
10.1186/s13023-023-02804-4
. [PMID: 37480097] - Lu Yang, Jiuyang Zhao, Shaoli Fan, Jinfa Liao, Yicun Chen, Yangdong Wang. Effect of Frost on the Different Metabolites of Two Mulberry (Morus nigra L. and Morus alba L.) Leaves.
Molecules (Basel, Switzerland).
2023 Jun; 28(12):. doi:
10.3390/molecules28124718
. [PMID: 37375273] - Henryk Straube. Am-aza-ing antidiabetic: Mulberry dehydrogenase MnGUTB1 contributes to the biosynthesis of 1-deoxynojirimycin.
Plant physiology.
2023 05; 192(2):700-702. doi:
10.1093/plphys/kiad140
. [PMID: 36880315] - Zhen Yang, Yiwei Luo, Xiaoyu Xia, Jinzhi He, Jiajia Zhang, Qiwei Zeng, Dong Li, Bi Ma, Shaoyu Zhang, Changxin Zhai, Miao Chen, Ningjia He. Dehydrogenase MnGutB1 catalyzes 1-deoxynojirimycin biosynthesis in mulberry.
Plant physiology.
2023 Feb; ?(?):. doi:
10.1093/plphys/kiad065
. [PMID: 36800200] - Dujun Wang, Li Zhao, Jingqiong Wan, Jia Liu, Yuan Wei, Zhen Ouyang, Xiaohong Yu. Molecular cloning, expression, and functional analysis of copper amine oxidase gene from mulberry (Morus alba L.).
Protein expression and purification.
2023 01; 201(?):106166. doi:
10.1016/j.pep.2022.106166
. [PMID: 36174814] - Veronica Antipova, Lisa-Marie Steinhoff, Carsten Holzmann, Arndt Rolfs, Carlos Junior Hempel, Martin Witt, Andreas Wree. Organ Weights in NPC1 Mutant Mice Partly Normalized by Various Pharmacological Treatment Approaches.
International journal of molecular sciences.
2022 Dec; 24(1):. doi:
10.3390/ijms24010573
. [PMID: 36614015] - Agata Walkowiak-Bródka, Natalia Piekuś-Słomka, Kacper Wnuk, Bogumiła Kupcewicz. Analysis of White Mulberry Leaves and Dietary Supplements, ATR-FTIR Combined with Chemometrics for the Rapid Determination of 1-Deoxynojirimycin.
Nutrients.
2022 Dec; 14(24):. doi:
10.3390/nu14245276
. [PMID: 36558434] - F Wen, P Dai, Z Song, C Jin, X Ji, J Hou, N Liu. Alleviating effect of mulberry leaf 1-deoxynojirimycin on resistin-induced hepatic steatosis and insulin resistance in mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2022 Dec; 73(6):. doi:
10.26402/jpp.2022.6.07
. [PMID: 37087566] - Pin-Jian Xiao, Jia-Cheng Zeng, Ping Lin, Dao-Bang Tang, En Yuan, Yong-Gang Tu, Qing-Feng Zhang, Ji-Guang Chen, Da-Yong Peng, Zhong-Ping Yin. Chalcone-1-Deoxynojirimycin Heterozygote Reduced the Blood Glucose Concentration and Alleviated the Adverse Symptoms and Intestinal Flora Disorder of Diabetes Mellitus Rats.
Molecules (Basel, Switzerland).
2022 Nov; 27(21):. doi:
10.3390/molecules27217583
. [PMID: 36364410] - Kamonpan Fongsodsri, Thanchanit Thaipitakwong, Kitiya Rujimongkon, Tapanee Kanjanapruthipong, Sumate Ampawong, Onrapak Reamtong, Pornanong Aramwit. Mulberry-Derived 1-Deoxynojirimycin Prevents Type 2 Diabetes Mellitus Progression via Modulation of Retinol-Binding Protein 4 and Haptoglobin.
Nutrients.
2022 Oct; 14(21):. doi:
10.3390/nu14214538
. [PMID: 36364802] - Fanshan Feng, Wei Xiang, Han Gao, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, Xianzhi Huang, Li Xu. Rapid Screening of Nonalkaloid α-Glucosidase Inhibitors from a Mulberry Twig Extract Using Enzyme-Functionalized Magnetic Nanoparticles Coupled with UPLC-MS/MS.
Journal of agricultural and food chemistry.
2022 Sep; 70(38):11958-11966. doi:
10.1021/acs.jafc.2c03435
. [PMID: 36107153] - Laura López de Frutos, Francisco Almeida, Jessica Murillo-Saich, Vasco A Conceição, Monica Guma, Oswald Queheberger, Pilar Giraldo, Gabriel Miltenberger-Miltenyi. Serum Phospholipid Profile Changes in Gaucher Disease and Parkinson's Disease.
International journal of molecular sciences.
2022 Sep; 23(18):. doi:
10.3390/ijms231810387
. [PMID: 36142296] - Hamid Momeni, Ashraf Salehi, Abdorrahim Absalan, Mehran Akbari. Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c\% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silico analysis.
Journal of complementary & integrative medicine.
2022 Sep; 19(3):763-769. doi:
10.1515/jcim-2021-0005
. [PMID: 33946137] - Tatiane G Hammerschmidt, Bruna Donida, Jéssica L Faverzani, Alana P Moura, Bianca G Dos Reis, Andryele Z Machado, Rejane G Kessler, Fernanda M Sebastião, Luiza S Reinhardt, Dinara J Moura, Carmen R Vargas. Cytokine profile and cholesterol levels in patients with Niemann-Pick type C disease presenting neurological symptoms: in vivo effect of miglustat and in vitro effect of N-acetylcysteine and coenzyme Q10.
Experimental cell research.
2022 07; 416(2):113175. doi:
10.1016/j.yexcr.2022.113175
. [PMID: 35487270] - Xinxiu Ren, Yan Xing, Liangyu He, Zhilong Xiu, Ling Yang, Aizhi Han, Qinhua Jia, Yuesheng Dong. Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Journal of ethnopharmacology.
2022 May; 289(?):115029. doi:
10.1016/j.jep.2022.115029
. [PMID: 35077826] - Jingqiong Wan, Yangzhen Liao, Jia Liu, Wenmin Du, Chang Liu, Yuan Wei, Zhen Ouyang. Screening, cloning and functional characterization of key methyltransferase genes involved in the methylation step of 1-deoxynojirimycin alkaloids biosynthesis in mulberry leaves.
Planta.
2022 May; 255(6):121. doi:
10.1007/s00425-022-03901-7
. [PMID: 35538157] - Malte Lenders, Peter Nordbeck, Christine Kurschat, Maria Eveslage, Nesrin Karabul, Jessica Kaufeld, Julia B Hennermann, Monica Patten, Markus Cybulla, Jonas Müntze, Nurcan Üçeyler, Dan Liu, Anibh M Das, Claudia Sommer, Christian Pogoda, Stefanie Reiermann, Thomas Duning, Jens Gaedeke, Katharina von Cossel, Daniela Blaschke, Stefan-Martin Brand, W Alexander Mann, Christoph Kampmann, Nicole Muschol, Sima Canaan-Kühl, Eva Brand. Treatment of Fabry Disease management with migalastat-outcome from a prospective 24 months observational multicenter study (FAMOUS).
European heart journal. Cardiovascular pharmacotherapy.
2022 05; 8(3):272-281. doi:
10.1093/ehjcvp/pvab025
. [PMID: 35512362] - Yifang Gao, Wenhui Bian, Yuanyuan Fang, Peng Du, Xueting Liu, Xueru Zhao, Fengjuan Li. α-Glucosidase Inhibitory Activity of Fermented Okara Broth Started with the Strain Bacillus amyloliquefaciens SY07.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27031127
. [PMID: 35164396] - Saligrama Viswanath Shreelakshmi, Maria Sheeba Nazareth, Pradeep Matam, Darshan Dorairaj, Nandini P Shetty. Chemometric evaluation of functional components and anti-quorum sensing activity of mulberry leaves from Indian cultivars: a potential contribution to the food industry.
Journal of the science of food and agriculture.
2022 Jan; 102(2):567-574. doi:
10.1002/jsfa.11385
. [PMID: 34148238] - Julien Lamontagne, Eszter Sas, Gilles Vincent, Kankan Shang, Frédéric E Pitre, Michel Labrecque. Valuable alkaloids content is preserved in Camptotheca acuminata and Morus alba grown in trace elements contaminated soil.
International journal of phytoremediation.
2022; 24(14):1533-1542. doi:
10.1080/15226514.2022.2043238
. [PMID: 35234104] - Isabella Supardi Parida, Soo Takasu, Kiyotaka Nakagawa. A comprehensive review on the production, pharmacokinetics and health benefits of mulberry leaf iminosugars: Main focus on 1-deoxynojirimycin, d-fagomine, and 2-O-ɑ-d-galactopyranosyl-DNJ.
Critical reviews in food science and nutrition.
2021 Oct; ?(?):1-29. doi:
10.1080/10408398.2021.1989660
. [PMID: 34658276] - Yasushi Honda, Anna Ozaki, Michihiro Iwaki, Takashi Kobayashi, Asako Nogami, Takaomi Kessoku, Yuji Ogawa, Wataru Tomeno, Kento Imajo, Masato Yoneda, Satoru Saito, Yoji Nagashima, Atsushi Nakajima. Protective effect of SGL5213, a potent intestinal sodium-glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice.
Journal of pharmacological sciences.
2021 Oct; 147(2):176-183. doi:
10.1016/j.jphs.2021.07.002
. [PMID: 34384565] - Parsa Bazdar, Ali R Jalalvand, Vali Akbari, Reza Khodarahmi, Hector C Goicoechea. Resolving interactions of miglitol with normal and glycated human serum albumin by multivariate methods.
Analytical biochemistry.
2021 10; 630(?):114339. doi:
10.1016/j.ab.2021.114339
. [PMID: 34411552] - Jia Liu, Jingqiong Wan, Wenmin Du, Dujun Wang, Chongwei Wen, Yuan Wei, Zhen Ouyang. In Vivo Functional Verification of Four Related Genes Involved in the 1-Deoxynojirimycin Biosynthetic Pathway in Mulberry Leaves.
Journal of agricultural and food chemistry.
2021 Sep; 69(37):10989-10998. doi:
10.1021/acs.jafc.1c03932
. [PMID: 34516110] - X He, Z Sun, K Ma, Y Mei. [1-deoxynojirimycin alleviates liver fibrosis induced by type 2 diabetes in mice].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2021 Aug; 41(9):1342-1349. doi:
10.12122/j.issn.1673-4254.2021.09.08
. [PMID: 34658348] - Juan Yan, Xiao-Min Li, Yan-Xin Zhang, Su-Mei Xu, Wan-Li Liu, Jie Guo, Xiao-Lei Hu, Ting Zou, Yu-Ying Xu, Ping-Sheng Xu. Bioequivalence and Evaluation Parameters Based on the Pharmacodynamics of Miglitol in Healthy Volunteers.
Clinical pharmacology in drug development.
2021 06; 10(6):582-587. doi:
10.1002/cpdd.873
. [PMID: 33058553] - Ichiro Misumi, Zhucui Li, Lu Sun, Anshuman Das, Tomoyuki Shiota, John Cullen, Qibin Zhang, Jason K Whitmire, Stanley M Lemon. Iminosugar Glucosidase Inhibitors Reduce Hepatic Inflammation in Hepatitis A Virus-Infected Ifnar1-/- Mice.
Journal of virology.
2021 05; 95(11):e0005821. doi:
10.1128/jvi.00058-21
. [PMID: 33692213] - Elizabeth C Clarke, Robert A Nofchissey, Chunyan Ye, Steven B Bradfute. The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication.
Glycobiology.
2021 05; 31(4):378-384. doi:
10.1093/glycob/cwaa091
. [PMID: 32985653] - Sreejith Rajasekharan, Rafaela Milan Bonotto, Lais Nascimento Alves, Yvette Kazungu, Monica Poggianella, Pamela Martinez-Orellana, Natasa Skoko, Sulena Polez, Alessandro Marcello. Inhibitors of Protein Glycosylation Are Active against the Coronavirus Severe Acute Respiratory Syndrome Coronavirus SARS-CoV-2.
Viruses.
2021 04; 13(5):. doi:
10.3390/v13050808
. [PMID: 33946304] - Fumitaka Okajima, Hitoshi Sugihara, Naoya Emoto. Efficacy and Safety of Miglitol- or Repaglinide-Based Combination Therapy with Alogliptin for Drug-Naïve Patients with Type 2 Diabetes: An Open-Label, Single-Center, Parallel, Randomized Controlled Pilot Study.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.
2021 Mar; 88(1):71-79. doi:
10.1272/jnms.jnms.2021_88-205
. [PMID: 32475902] - Salma Hago, Engy A Mahrous, Mohamed Moawad, Samia Abdel-Wahab, Essam Abdel-Sattar. Evaluation of antidiabetic activity of Morus nigra L. and Bauhinia variegata L. leaves as Egyptian remedies used for the treatment of diabetes.
Natural product research.
2021 Mar; 35(5):829-835. doi:
10.1080/14786419.2019.1601094
. [PMID: 30968706] - Masato Minami, Emiko Mizuma, Mai Nakahara, Yumi Oda, Haruhito Yoshimine, Koki Tokunaga, Akihiko Mitsuke, Yasutoshi Yamada, Hideki Enokida, Kosuke Masutani, Norihiko Goto, Akio Ido. A case of latent heterozygous Fabry disease in a female living kidney donor candidate.
CEN case reports.
2021 02; 10(1):30-34. doi:
10.1007/s13730-020-00510-9
. [PMID: 32712909] - Yuting Wang, Zhongwei Yu, Jun Jiang, Yaxin Li, Shui Yu. Mulberry leaf attenuates atherosclerotic lesions in patients with coronary heart disease possibly via 1-Deoxynojirimycin: A placebo-controlled, double-blind clinical trial.
Journal of food biochemistry.
2021 01; 45(1):e13573. doi:
10.1111/jfbc.13573
. [PMID: 33277698] - Haijun Wang, Yin Shen, Lei Zhao, Youfan Ye. 1-Deoxynojirimycin and its Derivatives: A Mini Review of the Literature.
Current medicinal chemistry.
2021; 28(3):628-643. doi:
10.2174/0929867327666200114112728
. [PMID: 31942844] - Daniel G Bichet, Johannes M Aerts, Christiane Auray-Blais, Hiroki Maruyama, Atul B Mehta, Nina Skuban, Eva Krusinska, Raphael Schiffmann. Assessment of plasma lyso-Gb3 for clinical monitoring of treatment response in migalastat-treated patients with Fabry disease.
Genetics in medicine : official journal of the American College of Medical Genetics.
2021 01; 23(1):192-201. doi:
10.1038/s41436-020-00968-z
. [PMID: 32994552] - Eleonora Riccio, Mario Zanfardino, Lucia Ferreri, Ciro Santoro, Sirio Cocozza, Ivana Capuano, Massimo Imbriaco, Sandro Feriozzi, Antonio Pisani. Switch from enzyme replacement therapy to oral chaperone migalastat for treating fabry disease: real-life data.
European journal of human genetics : EJHG.
2020 12; 28(12):1662-1668. doi:
10.1038/s41431-020-0677-x
. [PMID: 32647377] - Ping Lin, Jia-Cheng Zeng, Ji-Guang Chen, Xu-Liang Nie, En Yuan, Xiao-Qiang Wang, Da-Yong Peng, Zhong-Ping Yin. Synthesis, in vitro inhibitory activity, kinetic study and molecular docking of novel N-alkyl-deoxynojirimycin derivatives as potential α-glucosidase inhibitors.
Journal of enzyme inhibition and medicinal chemistry.
2020 Dec; 35(1):1879-1890. doi:
10.1080/14756366.2020.1826941
. [PMID: 33003963] - Jia Liu, Jingqiong Wan, Dujun Wang, Chongwei Wen, Yuan Wei, Zhen Ouyang. Comparative Transcriptome Analysis of Key Reductase Genes Involved in the 1-Deoxynojirimycin Biosynthetic Pathway in Mulberry Leaves and Cloning, Prokaryotic Expression, and Functional Analysis of MaSDR1 and MaSDR2.
Journal of agricultural and food chemistry.
2020 Nov; 68(44):12345-12357. doi:
10.1021/acs.jafc.0c04832
. [PMID: 33085468] - Qirui Hou, Zhongyao Qian, Ping Wu, Manman Shen, Long Li, Weiguo Zhao. 1-Deoxynojirimycin from mulberry leaves changes gut digestion and microbiota composition in geese.
Poultry science.
2020 Nov; 99(11):5858-5866. doi:
10.1016/j.psj.2020.07.048
. [PMID: 33142503] - Markus S Mueller, Patricia N Sidharta, Christine Voors-Pette, Borje Darpo, Hongqi Xue, Jasper Dingemanse. The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects.
Orphanet journal of rare diseases.
2020 10; 15(1):303. doi:
10.1186/s13023-020-01582-7
. [PMID: 33109218] - Hila Braunstein, Maria Papazian, Gali Maor, Jan Lukas, Arndt Rolfs, Mia Horowitz. Misfolding of Lysosomal α-Galactosidase a in a Fly Model and Its Alleviation by the Pharmacological Chaperone Migalastat.
International journal of molecular sciences.
2020 Oct; 21(19):. doi:
10.3390/ijms21197397
. [PMID: 33036426] - Ulla Feldt-Rasmussen, Derralynn Hughes, Gere Sunder-Plassmann, Suma Shankar, Khan Nedd, Iacopo Olivotto, Damara Ortiz, Toya Ohashi, Takashi Hamazaki, Nina Skuban, Julie Yu, Jay A Barth, Kathleen Nicholls. Long-term efficacy and safety of migalastat treatment in Fabry disease: 30-month results from the open-label extension of the randomized, phase 3 ATTRACT study.
Molecular genetics and metabolism.
2020 Sep; 131(1-2):219-228. doi:
10.1016/j.ymgme.2020.07.007
. [PMID: 33012654] - Yue-Sheng Dong, Na Yu, Xia Li, Bowei Zhang, Yan Xing, Chunlin Zhuang, Zhi-Long Xiu. Dietary 5,6,7-Trihydroxy-flavonoid Aglycones and 1-Deoxynojirimycin Synergistically Inhibit the Recombinant Maltase-Glucoamylase Subunit of α-Glucosidase and Lower Postprandial Blood Glucose.
Journal of agricultural and food chemistry.
2020 Aug; 68(33):8774-8787. doi:
10.1021/acs.jafc.0c01668
. [PMID: 32806121] - Malte Lenders, Peter Nordbeck, Christine Kurschat, Nesrin Karabul, Jessica Kaufeld, Julia B Hennermann, Monica Patten, Markus Cybulla, Jonas Müntze, Nurcan Üçeyler, Dan Liu, Anibh M Das, Claudia Sommer, Christian Pogoda, Stefanie Reiermann, Thomas Duning, Jens Gaedeke, Katharina Stumpfe, Daniela Blaschke, Stefan-Martin Brand, W Alexander Mann, Christoph Kampmann, Nicole Muschol, Sima Canaan-Kühl, Eva Brand. Treatment of Fabry's Disease With Migalastat: Outcome From a Prospective Observational Multicenter Study (FAMOUS).
Clinical pharmacology and therapeutics.
2020 08; 108(2):326-337. doi:
10.1002/cpt.1832
. [PMID: 32198894] - Anne Gläser, Franziska Hammerl, Markus H Gräler, Sina M Coldewey, Christin Völkner, Moritz J Frech, Fan Yang, Jiankai Luo, Eric Tönnies, Oliver von Bohlen Und Halbach, Nicola Brandt, Diana Heimes, Anna-Maria Neßlauer, Georg Christoph Korenke, Marta Owczarek-Lipska, John Neidhardt, Arndt Rolfs, Andreas Wree, Martin Witt, Anja Ursula Bräuer. Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism.
International journal of molecular sciences.
2020 Jun; 21(12):. doi:
10.3390/ijms21124502
. [PMID: 32599915] - Soo Takasu, Isabella S Parida, Junya Ito, Yoshihiro Kojima, Takahiro Eitsuka, Toshiyuki Kimura, Kiyotaka Nakagawa. Intestinal Absorption and Tissue Distribution of Aza-Sugars from Mulberry Leaves and Evaluation of Their Transport by Sugar Transporters.
Journal of agricultural and food chemistry.
2020 Jun; 68(24):6656-6663. doi:
10.1021/acs.jafc.0c03005
. [PMID: 32449853] - Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa. Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue.
Food & function.
2020 May; 11(5):3926-3940. doi:
10.1039/d0fo00271b
. [PMID: 32374310] - María de la Concepción Fournier Del Castillo, Silvia Cámara Barrio, Borja Esteso Orduña, Izaskun Basterra Jiménez, Laura López Marín, Verónica Cantarín Extremera, Luis González Gutiérrez-Solana. Long-term normalization of cognitive and psychopathological alterations in a juvenile Niemann-Pick type C case.
Neurodegenerative disease management.
2020 04; 10(2):73-80. doi:
10.2217/nmt-2019-0022
. [PMID: 32351165] - Graham Brogden, Hadeel Shammas, Friederike Walters, Katia Maalouf, Anibh M Das, Hassan Y Naim, Sandra Rizk. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability.
International journal of molecular sciences.
2020 Mar; 21(6):. doi:
10.3390/ijms21062101
. [PMID: 32204338] - Thanchanit Thaipitakwong, Ouppatham Supasyndh, Yousef Rasmi, Pornanong Aramwit. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes.
Complementary therapies in medicine.
2020 Mar; 49(?):102292. doi:
10.1016/j.ctim.2019.102292
. [PMID: 32147046] - Marie-Laure Boof, Atef Halabi, Mike Ufer, Jasper Dingemanse. Impact of the organic cation transporter 2 inhibitor cimetidine on the single-dose pharmacokinetics of the glucosylceramide synthase inhibitor lucerastat in healthy subjects.
European journal of clinical pharmacology.
2020 Mar; 76(3):431-437. doi:
10.1007/s00228-019-02808-9
. [PMID: 31836927] - Yu-Ying Xu, Su-Mei Xu, Xiao-Min Li, Dai Li, Juan Yan, Ping-Sheng Xu. Validation of the ADVIA Centaur® XP system for the determination of insulin and its application.
Analytical biochemistry.
2020 02; 591(?):113567. doi:
10.1016/j.ab.2019.113567
. [PMID: 31881181] - Ichiei Narita, Toya Ohashi, Norio Sakai, Takashi Hamazaki, Nina Skuban, Jeffrey P Castelli, Hjalmar Lagast, Jay A Barth. Efficacy and safety of migalastat in a Japanese population: a subgroup analysis of the ATTRACT study.
Clinical and experimental nephrology.
2020 Feb; 24(2):157-166. doi:
10.1007/s10157-019-01810-w
. [PMID: 31889231] - Sanzana Hoque, Yuki Kondo, Nodoka Sakata, Yusei Yamada, Madoka Fukaura, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Katsumi Higaki, Akio Hayashi, Takaki Komiya, Yoichi Ishitsuka, Tetsumi Irie. Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells.
International journal of molecular sciences.
2020 Jan; 21(3):. doi:
10.3390/ijms21030898
. [PMID: 32019132] - Guang-Yi Dai, Jian Yin, Kai-En Li, Ding-Kang Chen, Zhe Liu, Fang-Cheng Bi, Chan Rong, Nan Yao. The Arabidopsis AtGCD3 protein is a glucosylceramidase that preferentially hydrolyzes long-acyl-chain glucosylceramides.
The Journal of biological chemistry.
2020 01; 295(3):717-728. doi:
10.1074/jbc.ra119.011274
. [PMID: 31819005] - Maria Cristina Costanzo, Antonio Gennaro Nicotera, Mirella Vinci, Aurelio Vitello, Agata Fiumara, Francesco Calì, Sebastiano Antonino Musumeci. Novel compound heterozygous mutation in NPC1 gene cause Niemann-Pick disease type C with juvenile onset.
Journal of genetics.
2020; 99(?):. doi:
. [PMID: 32482919]
- Patrícia Varela, Gianna Mastroianni Kirsztajn, Henrique Ferrer, Carolina Aranda, Krissia Wallbach, Gustavo Ferreira da Mata, Luiz A Moura, Sílvia R Moreira, Carmen Mendes, Marco A Curiati, Ana Maria Martins, João Bosco Pesquero. Functional Characterization and Pharmacological Evaluation of a Novel GLA Missense Mutation Found in a Severely Affected Fabry Disease Family.
Nephron.
2020; 144(3):147-155. doi:
10.1159/000503998
. [PMID: 31665721] - Vijayalaxmi Gupta, Sheri A Hild, Sudhakar R Jakkaraj, Erick J Carlson, Henry L Wong, C. Leigh Allen, Gunda I Georg, Joseph S Tash. N-Butyldeoxygalactonojirimycin Induces Reversible Infertility in Male CD Rats.
International journal of molecular sciences.
2019 12; 21(1):. doi:
10.3390/ijms21010301
. [PMID: 31906257] - Daniela Herrera Moro Chao, Yanan Wang, Ewout Foppen, Roelof Ottenhoff, Cindy van Roomen, Edwin T Parlevliet, Marco van Eijk, Marri Verhoek, Rolf Boot, Andre R Marques, Saskia Scheij, Mina Mirzaian, Sander Kooijman, Kirstin Jansen, Dawei Wang, Clarita Mergen, Randy J Seeley, Matthias H Tschöp, Herman Overkleeft, Patrick C N Rensen, Andries Kalsbeek, Johannes M F G Aerts, Chun-Xia Yi. The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
Diabetes.
2019 12; 68(12):2223-2234. doi:
10.2337/db19-0049
. [PMID: 31578192] - Rodolfo Tonin, Anna Caciotti, Elena Procopio, Rita Fischetto, Federica Deodato, Maria Margherita Mancardi, Maja Di Rocco, Anna Ardissone, Alessandro Salviati, Antonio Marangi, Pietro Strisciuglio, Giusi Mangone, Arianna Casini, Silvia Ricci, Agata Fiumara, Rossella Parini, Francesco Saverio Pavone, Renzo Guerrini, Martino Calamai, Amelia Morrone. Pre-diagnosing and managing patients with GM1 gangliosidosis and related disorders by the evaluation of GM1 ganglioside content.
Scientific reports.
2019 11; 9(1):17684. doi:
10.1038/s41598-019-53995-5
. [PMID: 31776384] - Genki Naruse, Hiromitsu Kanamori, Akihiro Yoshida, Shingo Minatoguchi, Tomonori Kawaguchi, Masamitsu Iwasa, Yoshihisa Yamada, Atsushi Mikami, Masanori Kawasaki, Kazuhiko Nishigaki, Shinya Minatoguchi. The intestine responds to heart failure by enhanced mitochondrial fusion through glucagon-like peptide-1 signalling.
Cardiovascular research.
2019 Nov; 115(13):1873-1885. doi:
10.1093/cvr/cvz002
. [PMID: 30629149] - Meher Lad, Rhys H Thomas, Kirstie Anderson, Timothy D Griffiths. Niemann-Pick type C: contemporary diagnosis and treatment of a classical disorder.
Practical neurology.
2019 Oct; 19(5):420-423. doi:
10.1136/practneurol-2019-002236
. [PMID: 31243140] - Junping Zheng, Lin Zhu, Baifei Hu, Xiaojuan Zou, Haiming Hu, Zhigang Zhang, Nan Jiang, Jun Ma, Huabing Yang, Hongtao Liu. 1-Deoxynojirimycin improves high fat diet-induced nonalcoholic steatohepatitis by restoring gut dysbiosis.
The Journal of nutritional biochemistry.
2019 09; 71(?):16-26. doi:
10.1016/j.jnutbio.2019.05.013
. [PMID: 31272028] - Foudil Lamari, Wladimir Mauhin, Fairouz Koraichi, Walid Khrouf, Celine Bordet, Jonathan London, Olivier Lidove, Philippe Charron. Strong increase of leukocyte apha-galactosidase A activity in two male patients with Fabry disease following oral chaperone therapy.
Molecular genetics & genomic medicine.
2019 09; 7(9):e894. doi:
10.1002/mgg3.894
. [PMID: 31393666] - Dominique P Germain, Kathy Nicholls, Roberto Giugliani, Daniel G Bichet, Derralynn A Hughes, Laura M Barisoni, Robert B Colvin, J Charles Jennette, Nina Skuban, Jeffrey P Castelli, Elfrida Benjamin, Jay A Barth, Christopher Viereck. Efficacy of the pharmacologic chaperone migalastat in a subset of male patients with the classic phenotype of Fabry disease and migalastat-amenable variants: data from the phase 3 randomized, multicenter, double-blind clinical trial and extension study.
Genetics in medicine : official journal of the American College of Medical Genetics.
2019 09; 21(9):1987-1997. doi:
10.1038/s41436-019-0451-z
. [PMID: 30723321] - Teng-Gen Hu, Peng Wen, Wei-Zhi Shen, Fan Liu, Qian Li, Er-Na Li, Sen-Tai Liao, Hong Wu, Yu-Xiao Zou. Effect of 1-Deoxynojirimycin Isolated from Mulberry Leaves on Glucose Metabolism and Gut Microbiota in a Streptozotocin-Induced Diabetic Mouse Model.
Journal of natural products.
2019 08; 82(8):2189-2200. doi:
10.1021/acs.jnatprod.9b00205
. [PMID: 31393724] - Malte Lenders, Franciska Stappers, Christoph Niemietz, Boris Schmitz, Michel Boutin, Paula Johanna Ballmaier, Andree Zibert, Hartmut Schmidt, Stefan-Martin Brand, Christiane Auray-Blais, Eva Brand. Mutation-specific Fabry disease patient-derived cell model to evaluate the amenability to chaperone therapy.
Journal of medical genetics.
2019 08; 56(8):548-556. doi:
10.1136/jmedgenet-2019-106005
. [PMID: 31010832] - Renzo Mignani. [The Fabry nephropathy: new insight in diagnosis, monitoring and treatment].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia.
2019 Jul; 36(4):. doi:
NULL
. [PMID: 31373466] - Anna-Maria Neßlauer, Anne Gläser, Markus Gräler, Robby Engelmann, Brigitte Müller-Hilke, Marcus Frank, Christine Burstein, Arndt Rolfs, John Neidhardt, Andreas Wree, Martin Witt, Anja U Bräuer. A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1.
Lipids in health and disease.
2019 Jun; 18(1):146. doi:
10.1186/s12944-019-1088-2
. [PMID: 31248418] - Susan Oommen, Yanfeng Zhou, Muthuraman Meiyappan, Andrey Gurevich, Yongchang Qiu. Inter-assay variability influences migalastat amenability assessments among Fabry disease variants.
Molecular genetics and metabolism.
2019 05; 127(1):74-85. doi:
10.1016/j.ymgme.2019.04.005
. [PMID: 31036492] - Jonas Müntze, Daniel Gensler, Octavian Maniuc, Dan Liu, Tereza Cairns, Daniel Oder, Kai Hu, Kristina Lorenz, Stefan Frantz, Christoph Wanner, Peter Nordbeck. Oral Chaperone Therapy Migalastat for Treating Fabry Disease: Enzymatic Response and Serum Biomarker Changes After 1 Year.
Clinical pharmacology and therapeutics.
2019 05; 105(5):1224-1233. doi:
10.1002/cpt.1321
. [PMID: 30506669] - Emma H McCafferty, Lesley J Scott. Migalastat: A Review in Fabry Disease.
Drugs.
2019 Apr; 79(5):543-554. doi:
10.1007/s40265-019-01090-4
. [PMID: 30875019] - Hui Qi, Chen Kou, Yu-Jie Qi, Bo-Hao Tang, Yue-E Wu, Fei Jin, Xiao-Jing Luo, Yan-Hua Shen, Ya-Jie Guo, Xue Qi, Ya-Cui Wang, Qian Dong, Xing-Kai Chen, Hai-Yan Shi, Yi Zheng, Wei Zhao, A-Dong Shen. Population pharmacokinetics and dosing optimization of latamoxef in neonates and young infants.
International journal of antimicrobial agents.
2019 Mar; 53(3):347-351. doi:
10.1016/j.ijantimicag.2018.11.017
. [PMID: 30472290] - An-Na Li, Jun-Jun Chen, Qing-Qing Li, Guang-Yao Zeng, Qian-Yun Chen, Jun-Ling Chen, Zhi-Mei Liao, Ping Jin, Kuan-Song Wang, Zhi-Chun Yang. Alpha-glucosidase inhibitor 1-Deoxynojirimycin promotes beige remodeling of 3T3-L1 preadipocytes via activating AMPK.
Biochemical and biophysical research communications.
2019 02; 509(4):1001-1007. doi:
10.1016/j.bbrc.2019.01.023
. [PMID: 30654939] - Nuraniye Eruygur, Emrah Dural. Determination of 1-Deoxynojirimycin by a developed and validated HPLC-FLD method and assessment of In-vitro antioxidant, α-Amylase and α-Glucosidase inhibitory activity in mulberry varieties from Turkey.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Feb; 53(?):234-242. doi:
10.1016/j.phymed.2018.09.016
. [PMID: 30668403] - Mercedes Pineda, Katarína Juríčková, Parvaneh Karimzadeh, Miriam Kolnikova, Vera Malinova, Jose Luis Insua, Christian Velten, Stefan A Kolb. Disease characteristics, prognosis and miglustat treatment effects on disease progression in patients with Niemann-Pick disease Type C: an international, multicenter, retrospective chart review.
Orphanet journal of rare diseases.
2019 01; 14(1):32. doi:
10.1186/s13023-019-0996-6
. [PMID: 30732631] - Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Teruo Miyazawa, Takahiro Eitsuka, Kiyotaka Nakagawa. Physiological Effects and Organ Distribution of Bacillus amyloliquefaciens AS385 Culture Broth Powder Containing 1-Deoxynojirimycin in C57BL/6J Mice.
Journal of nutritional science and vitaminology.
2019; 65(2):157-163. doi:
10.3177/jnsv.65.157
. [PMID: 31061284] - Chi Zhou, Jin Huang, Guanglin Cui, Hesong Zeng, Dao Wen Wang, Qiang Zhou. Identification of a novel loss-of-function mutation of the GLA gene in a Chinese Han family with Fabry disease.
BMC medical genetics.
2018 12; 19(1):219. doi:
10.1186/s12881-018-0734-2
. [PMID: 30587147] - Eun-Young Lee, Xilin Zhang, Junki Miyamoto, Ikuo Kimura, Tomoaki Taknaka, Kenichi Furusawa, Takahito Jomori, Kosuke Fujimoto, Satoshi Uematsu, Takashi Miki. Gut carbohydrate inhibits GIP secretion via a microbiota/SCFA/FFAR3 pathway.
The Journal of endocrinology.
2018 12; 239(3):267-276. doi:
10.1530/joe-18-0241
. [PMID: 30400014] - Dujun Wang, Li Zhao, Jiayi Jiang, Jia Liu, Dan Wang, Xiaofeng Yu, Yuan Wei, Zhen Ouyang. Cloning, expression, and functional analysis of lysine decarboxylase in mulberry (Morus alba L.).
Protein expression and purification.
2018 11; 151(?):30-37. doi:
10.1016/j.pep.2018.06.004
. [PMID: 29894803] - Peng-Cheng Yan, Chao-Wei Wen, Shang-Zhi Zhang, Zhi-da Zhang, Jia-Ping Xu, Ming-Jie Deng. A toxicological, metabonomic and transcriptional analysis to investigate the property of mulberry 1-deoxynojirimycin against the growth of Samia cynthia ricini.
Pesticide biochemistry and physiology.
2018 Nov; 152(?):45-54. doi:
10.1016/j.pestbp.2018.08.009
. [PMID: 30497710] - Yann Nadjar, Ana Lucia Hütter-Moncada, Philippe Latour, Xavier Ayrignac, Elsa Kaphan, Christine Tranchant, Pascal Cintas, Adrian Degardin, Cyril Goizet, Chloe Laurencin, Lionel Martzolff, Caroline Tilikete, Mathieu Anheim, Bertrand Audoin, Vincent Deramecourt, Thierry Dubard De Gaillarbois, Emmanuel Roze, Foudil Lamari, Marie T Vanier, Bénédicte Héron. Adult Niemann-Pick disease type C in France: clinical phenotypes and long-term miglustat treatment effect.
Orphanet journal of rare diseases.
2018 10; 13(1):175. doi:
10.1186/s13023-018-0913-4
. [PMID: 30285904] - R W D Welford, A Mühlemann, M Garzotti, V Rickert, P M A Groenen, O Morand, N Üçeyler, M R Probst. Glucosylceramide synthase inhibition with lucerastat lowers globotriaosylceramide and lysosome staining in cultured fibroblasts from Fabry patients with different mutation types.
Human molecular genetics.
2018 10; 27(19):3392-3403. doi:
10.1093/hmg/ddy248
. [PMID: 29982630] - Weili Han, Xiangxiang Chen, Huimin Yu, Lingyun Chen, Mei Shen. Seasonal variations of iminosugars in mulberry leaves detected by hydrophilic interaction chromatography coupled with tandem mass spectrometry.
Food chemistry.
2018 Jun; 251(?):110-114. doi:
10.1016/j.foodchem.2018.01.058
. [PMID: 29426416] - Qing Zhao, Tian Zhu Jia, Qi Chen Cao, Fang Tian, Wan Tao Ying. A Crude 1-DNJ Extract from Home Made Bombyx Batryticatus Inhibits Diabetic Cardiomyopathy-Associated Fibrosis in db/db Mice and Reduces Protein N-Glycosylation Levels.
International journal of molecular sciences.
2018 Jun; 19(6):. doi:
10.3390/ijms19061699
. [PMID: 29880742] - Stefano Tozza, Raffaele Dubbioso, Rosa Iodice, Antonietta Topa, Marcello Esposito, Lucia Ruggiero, Emanuele Spina, Anna De Rosa, Francesco Saccà, Lucio Santoro, Fiore Manganelli. Long-term therapy with miglustat and cognitive decline in the adult form of Niemann-Pick disease type C: a case report.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2018 Jun; 39(6):1015-1019. doi:
10.1007/s10072-018-3314-5
. [PMID: 29536386] - Vijay Rayamajhi, Dipesh Dhakal, Amit Kumar Chaudhary, Jae Kyung Sohng. Improved production of 1-deoxynojirymicin in Escherichia coli through metabolic engineering.
World journal of microbiology & biotechnology.
2018 May; 34(6):77. doi:
10.1007/s11274-018-2462-3
. [PMID: 29796897] - Xiaodan Liu, Jianan Feng, Yan Li. Preparation of carbon-functionalized magnetic graphene/mesoporous silica composites for selective extraction of miglitol and voglibose in rat plasma.
Talanta.
2018 May; 182(?):405-413. doi:
10.1016/j.talanta.2018.01.079
. [PMID: 29501171] - Ting-Ting Tong, Er-Hu Zhao, Hai-Long Gao, Yong-Hui Xu, Yong-Ju Zhao, Gang Fu, Hong-Juan Cui. [Recent research advances of 1-deoxynojirimycin and its derivatives].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2018 May; 43(10):1990-1997. doi:
10.19540/j.cnki.cjcmm.20180125.010
. [PMID: 29933661] - Raphael Schiffmann, Daniel G Bichet, Ana Jovanovic, Derralynn A Hughes, Roberto Giugliani, Ulla Feldt-Rasmussen, Suma P Shankar, Laura Barisoni, Robert B Colvin, J Charles Jennette, Fred Holdbrook, Andrew Mulberg, Jeffrey P Castelli, Nina Skuban, Jay A Barth, Kathleen Nicholls. Migalastat improves diarrhea in patients with Fabry disease: clinical-biomarker correlations from the phase 3 FACETS trial.
Orphanet journal of rare diseases.
2018 04; 13(1):68. doi:
10.1186/s13023-018-0813-7
. [PMID: 29703262] - Nicolas Guérard, Daniel Oder, Peter Nordbeck, Christian Zwingelstein, Olivier Morand, Richard W D Welford, Jasper Dingemanse, Christoph Wanner. Lucerastat, an Iminosugar for Substrate Reduction Therapy: Tolerability, Pharmacodynamics, and Pharmacokinetics in Patients With Fabry Disease on Enzyme Replacement.
Clinical pharmacology and therapeutics.
2018 04; 103(4):703-711. doi:
10.1002/cpt.790
. [PMID: 28699267] - Lynn Ebner, Anne Gläser, Anja Bräuer, Martin Witt, Andreas Wree, Arndt Rolfs, Marcus Frank, Brigitte Vollmar, Angela Kuhla. Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann-Pick-Disease Type C1.
International journal of molecular sciences.
2018 Mar; 19(4):. doi:
10.3390/ijms19040972
. [PMID: 29587349]