Methyl 2-propenyl disulfide (BioDeep_00000006751)

 

Secondary id: BioDeep_00000865966, BioDeep_00001868134

human metabolite


代谢物信息卡片


3-(Methyldisulphanyl)-1-propene

化学式: C4H8S2 (120.0067)
中文名称: 烯丙基甲基二硫醚, 烯丙基甲基二硫化物
谱图信息: 最多检出来源 Homo sapiens(feces) 93.69%

分子结构信息

SMILES: C=CCSSC
InChI: InChI=1S/C4H8S2/c1-3-4-6-5-2/h3H,1,4H2,2H3

描述信息

Constituent of the essential oils of Allium subspecies Flavouring ingredient. Methyl 2-propenyl disulfide is found in many foods, some of which are garden onion, allium (onion), chives, and soft-necked garlic.
Methyl 2-propenyl disulfide is found in allium (onion). Methyl 2-propenyl disulfide is a constituent of the essential oils of Allium species Methyl 2-propenyl disulfide is a flavouring ingredient.

同义名列表

19 个代谢物同义名

3-(Methyldisulphanyl)-1-propene; 3-(Methyldisulfanyl)-1-propene; 3-(Methyldisulfanyl)prop-1-ene; Methyl 2-propenyl disulphide; Disulfide, methyl 2-propenyl; Methyl 2-propenyl disulfide; 3-(Methyldithio)prop-1-ene; 2-Propenylmethyldisulfide; Methyl allyl disulphide; Disulfide, allyl methyl; Allyl methyl disulphide; ALLYL METHYL DISULFIDE; Methylallyl disulphide; Methyl allyl disulfide; Methylallyl disulfide; 4,5-Dithia-1-hexene; FEMA 3127; Methyl allyl disulfide; Allyl methyl disulfide



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CYP2E1, CYP3A4, ELANE, HPGDS, NLRP3
Peripheral membrane protein 2 CYP2E1, GORASP1
Endoplasmic reticulum membrane 2 CYP2E1, CYP3A4
Nucleus 2 NLRP3, TRIM33
cytosol 3 ELANE, HPGDS, NLRP3
phagocytic vesicle 1 ELANE
nucleoplasm 2 HPGDS, TRIM33
Cell membrane 2 PTPRC, TNF
Cytoplasmic side 1 GORASP1
Golgi apparatus membrane 2 GORASP1, NLRP3
Synapse 1 PTPRC
cell surface 3 ELANE, PTPRC, TNF
Golgi apparatus 2 ATRN, GORASP1
Golgi membrane 2 GORASP1, NLRP3
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 NLRP3
plasma membrane 3 ATRN, PTPRC, TNF
Membrane 3 CYP3A4, NLRP3, PTPRC
extracellular exosome 3 ATRN, ELANE, PTPRC
endoplasmic reticulum 1 NLRP3
extracellular space 5 ATRN, CXCL10, CXCL8, ELANE, TNF
mitochondrion 1 NLRP3
intracellular membrane-bounded organelle 3 CYP2E1, CYP3A4, HPGDS
Microsome membrane 2 CYP2E1, CYP3A4
Single-pass type I membrane protein 2 ATRN, PTPRC
Secreted 3 CXCL10, CXCL8, NLRP3
extracellular region 5 CXCL10, CXCL8, ELANE, NLRP3, TNF
cytoplasmic side of plasma membrane 1 PTPRC
[Isoform 2]: Secreted 1 ATRN
external side of plasma membrane 3 CXCL10, PTPRC, TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 2 PTPRC, TNF
focal adhesion 1 PTPRC
cis-Golgi network 1 GORASP1
collagen-containing extracellular matrix 1 ELANE
secretory granule 1 ELANE
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
chromatin 1 TRIM33
phagocytic cup 1 TNF
[Isoform 3]: Secreted 1 ATRN
Endomembrane system 1 NLRP3
microtubule organizing center 1 NLRP3
secretory granule membrane 1 PTPRC
transcription repressor complex 1 ELANE
specific granule lumen 1 ELANE
azurophil granule lumen 1 ELANE
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
[Isoform 1]: Cell membrane 1 ATRN
Cytoplasmic vesicle, phagosome 1 ELANE
membrane microdomain 1 PTPRC
bleb 1 PTPRC
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yan Liu, Ang Li, Xiaoyan Jiang, Xiaosong Zhu, Xiuli Feng, Xiao Sun, Zhongxi Zhao. Metabolism and pharmacokinetics studies of allyl methyl disulfide in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2019 Jan; 49(1):90-97. doi: 10.1080/00498254.2017.1419309. [PMID: 29251532]
  • Ryan Munch, Sheryl A Barringer. Deodorization of garlic breath volatiles by food and food components. Journal of food science. 2014 Apr; 79(4):C526-33. doi: 10.1111/1750-3841.12394. [PMID: 24592995]
  • Ill-Min Chung, Hong-Keun Song, Min-A Yeo, Hyung-In Moon. Composition and immunotoxicity activity of major essential oils from stems of Allium victorialis L. var. platyphyllum Makino against Aedes aegypti L. Immunopharmacology and immunotoxicology. 2011 Sep; 33(3):480-3. doi: 10.3109/08923973.2010.539615. [PMID: 21162628]
  • R S Mann, R L Rouseff, J M Smoot, W S Castle, L L Stelinski. Sulfur volatiles from Allium spp. affect Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), response to citrus volatiles. Bulletin of entomological research. 2011 Feb; 101(1):89-97. doi: 10.1017/s0007485310000222. [PMID: 20609277]
  • Wenxia Zhang, Lee-Yong Lim. Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1283-90. doi: 10.1124/dmd.107.019737. [PMID: 18385293]
  • Premsiri Rotsatchakul, Siree Chaiseri, Keith R Cadwallader. Identification of characteristic aroma components of Thai fried chili paste. Journal of agricultural and food chemistry. 2008 Jan; 56(2):528-36. doi: 10.1021/jf072499n. [PMID: 18163558]
  • S Brenner, V Ruocco, R Wolf, E de Angelis, M L Lombardi. Pemphigus and dietary factors. In vitro acantholysis by allyl compounds of the genus Allium. Dermatology (Basel, Switzerland). 1995; 190(3):197-202. doi: 10.1159/000246684. [PMID: 7599380]