Dimethyldisulfide (BioDeep_00000006743)

 

Secondary id: BioDeep_00000865946, BioDeep_00001867642

human metabolite Endogenous


代谢物信息卡片


(Methyldisulfanyl)methane

化学式: C2H6S2 (93.9911)
中文名称: 二甲基二硫醚, 二甲基二硫化物
谱图信息: 最多检出来源 Rattus norvegicus(feces) 1.81%

分子结构信息

SMILES: CSSC
InChI: InChI=1S/C2H6S2/c1-3-4-2/h1-2H3

描述信息

Dimethyldisulfide is a volatile organic compound. Methyl disulfide is occasionally found as a volatile component of normal human breath and biofluids. Dimethyldisulfide is one of the representative volatile components found in oral malodor. Dimethyldisulfide concentrations in breath is a practical noninvasive way to assess recent exposure to sulfur compounds in sulfate pulp mills, and therefore it should be applicable to workplaces contaminated. (PMID: 5556886, 14691119, 11236158, 8481097).
Isolated from garlic oil (Allium sativum), also in onion (Allium cepa), ramsons (Allium ursinum), morello cherry, melon, pineapple, strawberry, wheat bread, cocoa, roasted barley, roasted filberts, roasted peanuts, crispbread, American potato chips, soybean and other foodstuffs. Flavouring ingredient.

同义名列表

18 个代谢物同义名

(Methyldisulfanyl)methane; Methyldisulfanylmethane; (methyldithio)Methane; Dimethyl disulphide; Methyldithiomethane; Disulfide dimethyl; Dimethyl disulfide; Dimethyldisulphide; Dimethyldisulfide; Sulfa-hitech 0382; Methyl disulphide; 2,3-Dithiabutane; Methyl disulfide; Methyldisulfide; Sulfa-hitech; DMDS; Dimethyl disulfide; Dimethyl disulfide



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

30 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ARHGAP45, BCLAF1, ODC1, PKIA, PMP2, PQBP1, SNRPN
Peripheral membrane protein 2 CHMP2A, NAPA
Endosome membrane 1 IGF2R
Endoplasmic reticulum membrane 2 FADS3, MOXD1
Nucleus 6 BCLAF1, HCK, PKIA, PMP2, PQBP1, SNRPN
cytosol 6 ARHGAP45, CHMP2A, HCK, NAPA, ODC1, PMP2
nuclear body 1 PQBP1
trans-Golgi network 1 IGF2R
nucleoplasm 3 BCLAF1, PQBP1, SNRPN
Cell membrane 2 NAPA, SLC38A5
Lipid-anchor 1 HCK
Cytoplasmic side 1 CHMP2A
ruffle membrane 1 ARHGAP45
Cytoplasmic granule 1 PQBP1
Multi-pass membrane protein 3 FADS3, SLC38A5, TSPAN6
Golgi apparatus membrane 1 IGF2R
cell surface 2 IGF2R, TNFRSF10B
glutamatergic synapse 1 NAPA
Golgi apparatus 3 ATRN, HCK, IGF2R
Golgi membrane 1 IGF2R
lysosomal membrane 1 CHMP2A
Lysosome 2 HCK, NAPA
Presynapse 1 NAPA
endosome 2 CHMP2A, IGF2R
plasma membrane 11 ARHGAP45, ATRN, CHMP2A, F2, HCK, IFNLR1, IGF2R, NAPA, SLC38A5, TNFRSF10B, TSPAN6
Membrane 10 ARHGAP45, CHMP2A, FADS3, IFNLR1, IGF2R, NAPA, PTCRA, SLC38A5, TNFRSF10B, TSPAN6
caveola 1 HCK
extracellular exosome 7 ATRN, CHMP2A, F2, IGF2R, NAPA, PMP2, TSPAN6
extracellular space 4 ATRN, F2, MOXD1, NAPA
perinuclear region of cytoplasm 1 IGF2R
intracellular membrane-bounded organelle 2 HCK, IGF2R
Single-pass type I membrane protein 5 ATRN, IFNLR1, IGF2R, MOXD1, PTCRA
Secreted 2 F2, NAPA
extracellular region 2 ARHGAP45, F2
cytoplasmic side of plasma membrane 1 HCK
[Isoform 2]: Secreted 1 ATRN
multivesicular body 1 CHMP2A
cytoplasmic vesicle 1 HCK
midbody 1 CHMP2A
Early endosome 1 IGF2R
Cell projection, ruffle membrane 1 ARHGAP45
Cell junction, focal adhesion 1 HCK
Cytoplasm, cytoskeleton 1 HCK
focal adhesion 2 HCK, IGF2R
collagen-containing extracellular matrix 1 F2
nuclear speck 2 BCLAF1, PQBP1
Late endosome 1 IGF2R
chromatin 1 CHMP2A
mediator complex 1 BCLAF1
Late endosome membrane 1 CHMP2A
autophagosome membrane 1 CHMP2A
cell projection 1 HCK
cytoskeleton 1 HCK
blood microparticle 1 F2
spliceosomal complex 1 SNRPN
[Isoform 2]: Cell membrane 1 HCK
[Isoform 3]: Secreted 1 ATRN
nuclear envelope 1 CHMP2A
nuclear pore 1 CHMP2A
Nucleus envelope 1 CHMP2A
Endomembrane system 1 IGF2R
Membrane, caveola 1 HCK
Nucleus, nucleoplasm 1 BCLAF1
cytoplasmic stress granule 1 PQBP1
Nucleus speckle 2 BCLAF1, PQBP1
myelin sheath 1 PMP2
trans-Golgi network membrane 1 IGF2R
multivesicular body membrane 1 CHMP2A
trans-Golgi network transport vesicle 1 IGF2R
secretory granule lumen 1 ARHGAP45
secretory granule membrane 2 IGF2R, MOXD1
Golgi lumen 1 F2
endoplasmic reticulum lumen 1 F2
kinetochore 1 CHMP2A
endocytic vesicle 1 IGF2R
transport vesicle 2 HCK, IGF2R
azurophil granule lumen 1 ARHGAP45
nuclear envelope lumen 1 IGF2R
clathrin-coated endocytic vesicle membrane 1 IGF2R
ribonucleoprotein complex 1 SNRPN
U2 snRNP 1 SNRPN
exon-exon junction complex 1 BCLAF1
[Isoform 1]: Cell membrane 1 ATRN
U4/U6 x U5 tri-snRNP complex 1 SNRPN
kinetochore microtubule 1 CHMP2A
catalytic step 2 spliceosome 1 SNRPN
membrane coat 1 CHMP2A
amphisome membrane 1 CHMP2A
ESCRT III complex 1 CHMP2A
neuronal ribonucleoprotein granule 1 PQBP1
U1 snRNP 1 SNRPN
U2-type prespliceosome 1 SNRPN
U5 snRNP 1 SNRPN
small nuclear ribonucleoprotein complex 1 SNRPN
alveolar lamellar body 1 NAPA
multivesicular body lumen 1 NAPA
clathrin coat 1 IGF2R
U4 snRNP 1 SNRPN
synaptobrevin 2-SNAP-25-syntaxin-1a complex 1 NAPA
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Ganyu Gu, Claire M Murphy, Jie Zheng, Xiangwu Nou, Steven L Rideout, Laura K Strawn. Effects of Fumigation on the Reduction of Salmonella enterica in Soil. Foodborne pathogens and disease. 2023 Sep; ?(?):. doi: 10.1089/fpd.2023.0031. [PMID: 37738333]
  • Qing Wang, Xin Wang, Daqi Zhang, Wensheng Fang, Yuan Li, Aocheng Cao, Qiuxia Wang, Dongdong Yan. Transcriptome reveals the toxicity difference of dimethyl disulfide by contact and fumigation on Meloidogyne incognita through calcium channel-mediated oxidative phosphorylation. Journal of hazardous materials. 2023 Aug; 460(?):132268. doi: 10.1016/j.jhazmat.2023.132268. [PMID: 37619272]
  • Lirui Ren, Wenjing Li, Daqi Zhang, Wensheng Fang, Dongdong Yan, Qiuxia Wang, Xi Jin, Yuan Li, Aocheng Cao. Silica modified copper-based alginate/chitosan hybrid hydrogel to control soil fumigant release, reduce emission and enhance bioactivity. International journal of biological macromolecules. 2023 May; ?(?):125132. doi: 10.1016/j.ijbiomac.2023.125132. [PMID: 37268067]
  • Gülnur Ekşi Bona, Gülşen Akalın Çiftçi, Betül Demirci, Nur Münevver Pınar, Aydan Acar Şahin, Mine Koçyiğit, Mehmet Bona, Ayşe Mine Gençler Özkan. Contributions of Chemical Content and Biological Activity to Plant Taxonomy Based on the Four Allium L. Taxa (Sect. Cupanioscordum - Amaryllidaceae). Chemistry & biodiversity. 2023 May; 20(5):e202201194. doi: 10.1002/cbdv.202201194. [PMID: 37027525]
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  • Xiujun Tang, Aocheng Cao, Yi Zhang, Xinhua Chen, Baoqiang Hao, Jin Xu, Wensheng Fang, Dongdong Yan, Yuan Li, Qiuxia Wang. Soil properties affect vapor-phase adsorption to regulate dimethyl disulfide diffusion in soil. The Science of the total environment. 2022 Jun; 825(?):154012. doi: 10.1016/j.scitotenv.2022.154012. [PMID: 35189207]
  • Guilong Ma, Xinxin Gao, Jie Nan, Tingting Zhang, Xiaobao Xie, Qi Cai. Fungicides alter the distribution and diversity of bacterial and fungal communities in ginseng fields. Bioengineered. 2021 12; 12(1):8043-8056. doi: 10.1080/21655979.2021.1982277. [PMID: 34595989]
  • Xianli Wang, Yi Zhang, Aocheng Cao, Jin Xu, Wensheng Fang, Dongdong Yan, Yuan Li, Qiuxia Wang. Effects of soil type, moisture content and organic amendment rate on dimethyl disulfide distribution and persistency in soil. Environmental pollution (Barking, Essex : 1987). 2021 Sep; 285(?):117198. doi: 10.1016/j.envpol.2021.117198. [PMID: 33957516]
  • Baoqiang Hao, Lirui Ren, Bin Huang, Xiujun Tang, Hongyan Cheng, Dongdong Yan, Yuan Li, Aocheng Cao, Canbin Ouyang, Qiuxia Wang. 2-Hydroxypropyl-β-cyclodextrin encapsulates dimethyl disulfide producing a controlled release formulation. The Science of the total environment. 2021 Jun; 773(?):145293. doi: 10.1016/j.scitotenv.2021.145293. [PMID: 33940723]
  • HyeonJi Kim, EunSeob Song, JaeHee Lee, Ravi Gautam, SoJung Shin, AhRang Cho, YeonGyeong Kim, SuJeong Yang, JiHun Jo, Manju Acharya, Anju Maharjan, ChangYul Kim, Yong Heo, HyoungAh Kim. Dysregulation of murine immune functions on inhalational exposure to ammonia, dimethyl disulfide, 3-methylindole, or propionic acid. Toxicology and industrial health. 2021 Apr; 37(4):219-228. doi: 10.1177/0748233721996559. [PMID: 33663293]
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  • Nan Fang, Zhou Lu, Zhongbei Zhang, Zhiguang Hou, Shuang Liang, Bo Wang, Shuo Wang, Zhongbin Lu. Dissipation and residues of dimethyl disulfide in tomatoes and soil under greenhouse and open field conditions. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2020; 55(6):566-573. doi: 10.1080/03601234.2020.1740531. [PMID: 32174229]
  • Liangang Mao, Hongyun Jiang, Lan Zhang, Yanning Zhang, Muhammad Umair Sial, Haitao Yu, Aocheng Cao. Assessment of the potential of a reduced dose of dimethyl disulfide plus metham sodium on soilborne pests and cucumber growth. Scientific reports. 2019 12; 9(1):19806. doi: 10.1038/s41598-019-56450-7. [PMID: 31875039]
  • Abdul Kaium, Junli Cao, Xingang Liu, Jun Xu, Fengshou Dong, Xiaohu Wu, Yongquan Zheng. Method Validation and Dissipation Behaviour of Dimethyl Disulphide (DMDS) in Cucumber and Soil by Gas Chromatography-Tandem Mass Spectrometry. International journal of environmental research and public health. 2019 11; 16(22):. doi: 10.3390/ijerph16224493. [PMID: 31739625]
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