Schottenol (BioDeep_00000637164)

Main id: BioDeep_00000007003

 

PANOMIX_OTCML-2023


代谢物信息卡片


(3S,5S,9R,10S,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

化学式: C29H50O (414.3861)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]([H])([C@]([H])(C)CC[C@@H](CC)C(C)C)CC[C@@]4([H])C3=CC[C@@]2([H])C[C@@H](O)C1
InChI: InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h11,19-23,25-27,30H,7-10,12-18H2,1-6H3/t20-,21-,22+,23+,25-,26+,27+,28+,29-/m1/s1

描述信息

同义名列表

11 个代谢物同义名

Schottenol; (3S,5S,9R,10S,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,5S,9R,10S,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,5S,9R,10S,13R,14R,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,5S,9R,10S,13R,14R,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; Stigmast-7-en-3beta-ol; LMST01040133; 521-03-9; C08839; ST 29:1;O; Schottenol



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AKT1, CAT, MAPK1, MAPK8, PTGS2, RELA, SLC2A2
Peripheral membrane protein 1 PTGS2
Endoplasmic reticulum membrane 4 ABCA1, ABCG1, CYP19A1, PTGS2
Nucleus 5 AKT1, ALX4, MAPK1, MAPK8, RELA
cytosol 6 ACOX1, AKT1, CAT, MAPK1, MAPK8, RELA
phagocytic vesicle 1 ABCA1
centrosome 1 MAPK1
nucleoplasm 5 AKT1, ALX4, MAPK1, MAPK8, RELA
Cell membrane 5 ABCA1, ABCG1, AKT1, SLC2A2, TNF
lamellipodium 1 AKT1
Multi-pass membrane protein 4 ABCA1, ABCG1, CYP19A1, SLC2A2
Golgi apparatus membrane 1 ABCG1
Synapse 2 MAPK1, MAPK8
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 2 AKT1, RELA
Golgi apparatus 3 ABCA1, ABCG1, MAPK1
Golgi membrane 2 ABCG1, INS
lysosomal membrane 1 GAA
neuronal cell body 1 TNF
postsynapse 1 AKT1
Lysosome 1 GAA
endosome 2 ABCA1, ABCG1
plasma membrane 8 ABCA1, ABCG1, AKT1, GAA, GCG, MAPK1, SLC2A2, TNF
Membrane 8 ABCA1, ABCG1, ACOX1, AKT1, CAT, CYP19A1, GAA, SLC2A2
apical plasma membrane 1 SLC2A2
axon 1 MAPK8
basolateral plasma membrane 1 ABCA1
brush border 1 SLC2A2
caveola 2 MAPK1, PTGS2
extracellular exosome 2 CAT, GAA
Lysosome membrane 1 GAA
endoplasmic reticulum 2 CYP19A1, PTGS2
extracellular space 4 GCG, IL17A, INS, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 ABCA1
mitochondrion 3 ABCG1, CAT, MAPK1
protein-containing complex 3 AKT1, CAT, PTGS2
intracellular membrane-bounded organelle 3 ABCA1, CAT, GAA
Microsome membrane 2 CYP19A1, PTGS2
Secreted 4 GAA, GCG, IL17A, INS
extracellular region 8 CAT, DNAH9, GAA, GCG, IL17A, INS, MAPK1, TNF
mitochondrial matrix 1 CAT
transcription regulator complex 2 ALX4, RELA
motile cilium 1 DNAH9
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 MAPK1
external side of plasma membrane 4 ABCA1, ABCG1, IL17A, TNF
microtubule cytoskeleton 1 AKT1
Early endosome 1 MAPK1
cell-cell junction 2 AKT1, SLC2A2
recycling endosome 2 ABCG1, TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 2 ABCA1, TNF
Cell junction, focal adhesion 1 MAPK1
Cytoplasm, cytoskeleton, spindle 1 MAPK1
focal adhesion 2 CAT, MAPK1
microtubule 1 DNAH9
spindle 2 AKT1, MAPK1
Peroxisome 2 ACOX1, CAT
intracellular vesicle 1 ABCA1
Peroxisome matrix 1 CAT
peroxisomal matrix 2 ACOX1, CAT
peroxisomal membrane 2 ACOX1, CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
axoneme 1 DNAH9
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 MAPK1
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 ALX4, RELA
phagocytic cup 1 TNF
mitotic spindle 1 MAPK1
cytoskeleton 1 MAPK1
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
endosome lumen 1 INS
Membrane, caveola 1 MAPK1
tertiary granule membrane 1 GAA
pseudopodium 1 MAPK1
ficolin-1-rich granule lumen 2 CAT, MAPK1
secretory granule lumen 3 CAT, GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 GCG, INS, MAPK1, PTGS2
endocytic vesicle 1 ABCA1
transport vesicle 1 INS
azurophil granule membrane 1 GAA
azurophil granule lumen 1 MAPK1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
autolysosome lumen 1 GAA
NF-kappaB p50/p65 complex 1 RELA
NF-kappaB complex 1 RELA
outer dynein arm 1 DNAH9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
distal portion of axoneme 1 DNAH9


文献列表

  • Farid Khallouki, Mohamed Ksila, Imen Ghzaiel, Soukaina Essadek, Mounia Tahri Joutey, Samah Maaloul, Wafa Zennouhi, Laila Benbacer, Mohamed Bourhia, Lhoussain Hajji, Amira Zarrouk, Leila Rezig, Sandrine Rup-Jacques, Raoudha Abdellaoui, Taoufik Ghrairi, Olfa Masmoudi-Kouki, Boubker Nasser, Pierre Andreoletti, Mustapha-Cherkaoui-Malki, Mohammad Samadi, Anne Vejux, Gérard Lizard. Chemical and Biochemical Features of Spinasterol and Schottenol. Advances in experimental medicine and biology. 2024; 1440(?):45-55. doi: 10.1007/978-3-031-43883-7_3. [PMID: 38036874]
  • Maqsood Ahmed, Allah Rakha Sajid, Ansar Javeed, Muhammad Aslam, Taswar Ahsan, Dilbar Hussain, Abdul Mateen, Xiuwei Li, Peiwen Qin, Mingshan Ji. Antioxidant, antifungal, and aphicidal activity of the triterpenoids spinasterol and 22,23-dihydrospinasterol from leaves of Citrullus colocynthis L. Scientific reports. 2022 03; 12(1):4910. doi: 10.1038/s41598-022-08999-z. [PMID: 35318417]
  • Maqsood Ahmed, Peiwen Qin, Mingshan Ji, Ran An, Hongxia Guo, Jamil Shafi. Spinasterol, 22,23-Dihydrospinasterol and Fernenol from Citrullus Colocynthis L. with Aphicidal Activity against Cabbage Aphid Brevicoryne Brassicae L. Molecules (Basel, Switzerland). 2020 May; 25(9):. doi: 10.3390/molecules25092184. [PMID: 32392823]
  • Garcia Gonzalez Jessica, Garcia Lorenzana Mario, Zamilpa Alejandro, Almanza Perez Julio Cesar, Jasso Villagomez E Ivan, Roman Ramos Ruben, Alarcon-Aguilar Francisco Javier. CHEMICAL CHARACTERIZATION OF A HYPOGLYCEMIC EXTRACT FROM CUCURBITA FICIFOLIA BOUCHE THAT INDUCES LIVER GLYCOGEN ACCUMULATION IN DIABETIC MICE. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2017; 14(3):218-230. doi: 10.21010/ajtcam.v14i3.24. [PMID: 28480434]
  • Linda H Münger, Sabrina Jutzi, Anna-Maija Lampi, Laura Nyström. Comparison of Enzymatic Hydrolysis and Acid Hydrolysis of Sterol Glycosides from Foods Rich in Δ(7)-Sterols. Lipids. 2015 Aug; 50(8):735-48. doi: 10.1007/s11745-015-4002-3. [PMID: 25757602]
  • Asmaa Badreddine, El Mostafa Karym, Amira Zarrouk, Thomas Nury, Youssef El Kharrassi, Boubker Nasser, Mustapha Cherkaoui Malki, Gérard Lizard, Mohammad Samadi. An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system. Steroids. 2015 Jul; 99(Pt B):119-24. doi: 10.1016/j.steroids.2015.01.005. [PMID: 25595450]
  • Youssef El Kharrassi, Mohammad Samadi, Tatiana Lopez, Thomas Nury, Riad El Kebbaj, Pierre Andreoletti, Hammam I El Hajj, Joseph Vamecq, Khadija Moustaid, Norbert Latruffe, M'Hammed Saïd El Kebbaj, David Masson, Gérard Lizard, Boubker Nasser, Mustapha Cherkaoui-Malki. Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells. Biochemical and biophysical research communications. 2014 Apr; 446(3):798-804. doi: 10.1016/j.bbrc.2014.02.074. [PMID: 24582563]
  • W S Chang, Y H Chang, F J Lu, H C Chiang. Inhibitory effects of phenolics on xanthine oxidase. Anticancer research. 1994 Mar; 14(2A):501-6. doi: . [PMID: 8017853]
  • Z Chao, J Liu. [Chemical constituents of the pericarp of Trichosanthes rosthornii Harms]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1991 Feb; 16(2):97-9, 127. doi: ". [PMID: 1872972]
  • K Yasukawa, S Yamanouchi, M Takido. [Studies on the constituents in the water extracts of crude drugs. III. On the roots of Stellaria dichotoma L. var. lanceolata Bge. (author's transl)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1981 Jan; 101(1):64-6. doi: 10.1248/yakushi1947.101.1_64. [PMID: 7252785]