Algestone (BioDeep_00000006138)

   


代谢物信息卡片


16alpha,17-dihydroxypregn-4-ene-3,20-dione

化学式: C21H30O4 (346.214398)
中文名称: 代数
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC2[C@]([C@]3([H])[C@]1([H])[C@@]1([H])[C@@](C)([C@](C(=O)C)(O)[C@H](O)C1)CC3)(C)CCC(=O)C=2
InChI: InChI=1S/C21H30O4/c1-12(22)21(25)18(24)11-17-15-5-4-13-10-14(23)6-8-19(13,2)16(15)7-9-20(17,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21-/m1/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents

同义名列表

5 个代谢物同义名

Algestone; 16alpha,17-dihydroxypregn-4-ene-3,20-dione; ST 21:3;O4; Alphasone; FT-0661485



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan Chen, Wan Shu Hong, Qiong Wang, Shi Xi Chen. Cloning and pattern of gsdf mRNA during gonadal development in the protogynous Epinephelus akaara. Animal reproduction science. 2016 Feb; 165(?):46-55. doi: 10.1016/j.anireprosci.2015.12.004. [PMID: 26718719]
  • A G Nieuwenhuizen, G A Schuiling, L G Hilbrands, E M Bisschop, T R Koiter. Proliferation of pancreatic islet-cells in cyclic and pregnant rats after treatment with progesterone. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1998 Nov; 30(11):649-55. doi: 10.1055/s-2007-978952. [PMID: 9918380]
  • M A Abdullah, D E Kime. Increased substrate concentration causes a shift from production of 11-oxygenated androgens to 17,20-dihydroxyprogestogens during the in vitro metabolism of 17-hydroxyprogesterone by goldfish testes. General and comparative endocrinology. 1994 Oct; 96(1):129-39. doi: 10.1006/gcen.1994.1165. [PMID: 7843561]
  • P M Gocze, D A Freeman. Plasma membrane cholesterol is utilized as steroidogenic substrate in Y-1 mouse adrenal tumor cells and normal sheep adrenal cells. Experimental cell research. 1993 Nov; 209(1):21-5. doi: 10.1006/excr.1993.1279. [PMID: 8224001]
  • D A Freeman, J A Ontko. Accumulation and mobilization of triglycerides and cholesteryl esters in Leydig tumor cells. Journal of lipid research. 1992 Aug; 33(8):1139-46. doi: 10.1016/s0022-2275(20)40765-5. [PMID: 1331282]
  • S Arakawa, A Kambegawa, S Okinaga, K Arai. Luteolytic effect of the antiprogestin and antiglucocorticoid agent RU486 in rats. Journal of steroid biochemistry. 1990 Aug; 36(5):479-83. doi: 10.1016/0022-4731(90)90091-6. [PMID: 2214764]
  • J C Wiemeyer, C L Sagasta, J M Roncales Mateo, A C Lavarello, L A Angel de Toro, R Salas Diaz. Multicentred clinical study of the metabolic effect of the monthly injectable contraceptive containing dihydroxyprogesterone acetophenide 150 mg + estradiol enanthate 10 mg. Contraception. 1990 Jul; 42(1):13-28. doi: 10.1016/0010-7824(90)90088-d. [PMID: 2117515]
  • F E Grissom, C L Brooks. A partial characterization of uterine and mammary growth stimulatory activity from placenta. Growth, development, and aging : GDA. 1988; 52(1):23-35. doi: . [PMID: 3139577]
  • M G Forest, E de Peretti, M P Monneret, A Lecoq, J Bertrand. [Kinetics of the testicular steroidogenic response to stimulation by placental gonadotropin hormone. VI. Enzyme deficiencies of testicular biosynthesis]. Archives francaises de pediatrie. 1985 Mar; 42(3):187-93. doi: NULL. [PMID: 3923993]
  • P Larochelle, P Du Souich, E Bolte, J Lelorier, R Goyer. Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application. Clinical pharmacology and therapeutics. 1983 Mar; 33(3):343-50. doi: 10.1038/clpt.1983.43. [PMID: 6402333]
  • C Shaha, G S Greenwald. In vivo and in vitro production of progestins by the corpus luteum of pregnancy of the hamster. Biology of reproduction. 1982 Jun; 26(5):854-60. doi: 10.1095/biolreprod26.5.854. [PMID: 6807363]
  • J E Damber, P O Janson, C Axén, G Selstam, A Cederblad, K Ahrén. Luteal blood flow and plasma steroids in rats with corpora lutea of different ages. Acta endocrinologica. 1981 Sep; 98(1):99-105. doi: 10.1530/acta.0.0980099. [PMID: 6792850]
  • P A Gilles, H J Karavolas. Effect of 20 alpha-dihydroprogesterone, progesterone, and their 5 alpha-reduced metabolites on serum gonadotropin levels and hypothalamic LHRH content. Biology of reproduction. 1981 Jun; 24(5):1088-97. doi: . [PMID: 6791716]
  • S K Saksena, I F Lau. Effects of prostaglandin-F2 alpha and a plant protein 'Trichosanthin', on 10-day pregnant rabbits. Prostaglandins and medicine. 1980 Nov; 5(5):383-90. doi: 10.1016/0161-4630(80)90110-x. [PMID: 6779302]
  • N P Goncharov, A Komor, N A Pachalia, A I Simarina, K Schubert. [Characteristics of the ovarianc cycle in the baboon (Papio hamadryas)]. Zentralblatt fur Gynakologie. 1978; 100(5):257-62. doi: NULL. [PMID: 349964]
  • H A Schut, J D Townsley. Oestrogen formation from C19 precursors in human choriocarcinoma in culture. Acta endocrinologica. 1977 Mar; 84(3):633-41. doi: 10.1530/acta.0.0840633. [PMID: 190843]
  • J P Coghlan, D A Denton, J S Fan, J G McDougall, B A Scoggins. Hypertensive effect of 17alpha, 20alpha-dihydroxyprogesterone and 17alpha-hydroxyprogesterone in the sheep. Nature. 1976 Oct; 263(5578):608-9. doi: 10.1038/263608a0. [PMID: 185522]