L-2-Aminoethyl seryl phosphate (BioDeep_00000005339)

 

Secondary id: BioDeep_00001870763

human metabolite Endogenous


代谢物信息卡片


2-amino-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propanoic acid

化学式: C5H13N2O6P (228.0511)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(plant) 11.55%

分子结构信息

SMILES: C(COP(=O)(O)OCC(C(=O)O)N)N
InChI: InChI=1S/C5H13N2O6P/c6-1-2-12-14(10,11)13-3-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)(H,10,11)



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, ANXA5, DAO, DMD, PKM, PLA2G12A, PML, RARA, VEGFA
Peripheral membrane protein 4 ANXA5, DAO, DMD, PML
Endoplasmic reticulum membrane 1 PML
Nucleus 6 ALB, DMD, PKM, PML, RARA, VEGFA
cytosol 8 ALB, ANXA5, DAO, DMD, IL1B, PKM, PML, RARA
dendrite 1 RARA
centrosome 1 ALB
nucleoplasm 3 ATP2B1, PML, RARA
RNA polymerase II transcription regulator complex 1 RARA
Cell membrane 5 ATP2B1, CD8A, DAO, ITGAM, TNF
Cytoplasmic side 2 DMD, PML
Early endosome membrane 1 PML
Multi-pass membrane protein 3 ATP2B1, CACNA1I, CRLS1
Synapse 2 ATP2B1, DMD
cell surface 4 DMD, ITGAM, TNF, VEGFA
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 ALB, VEGFA
Golgi membrane 1 INS
mitochondrial inner membrane 2 CRLS1, LDHD
neuronal cell body 1 TNF
presynaptic membrane 1 ATP2B1
sarcolemma 2 ANXA5, DMD
Cytoplasm, cytosol 2 DAO, IL1B
Lysosome 1 IL1B
plasma membrane 9 ATP2B1, CACNA1I, CD8A, DAO, DMD, ITGAM, PRAM1, RARA, TNF
presynaptic active zone 1 DAO
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ANXA5, ATP2B1, CACNA1I, CRLS1, DMD, ITGAM, VEGFA
basolateral plasma membrane 1 ATP2B1
extracellular exosome 7 ALB, ANXA5, ATP2B1, DAO, ITGAM, LYZ, PKM
endoplasmic reticulum 2 ALB, VEGFA
extracellular space 8 ALB, DAO, IL1B, INS, ITGAM, LYZ, TNF, VEGFA
perinuclear region of cytoplasm 1 RARA
adherens junction 1 VEGFA
bicellular tight junction 1 DAO
mitochondrion 3 CRLS1, LDHD, PKM
protein-containing complex 4 ALB, DMD, PRAM1, RARA
intracellular membrane-bounded organelle 1 ATP2B1
filopodium 1 DMD
Single-pass type I membrane protein 2 CD8A, ITGAM
Secreted 6 ALB, DAO, IL1B, INS, PLA2G12A, VEGFA
extracellular region 11 ALB, ANXA5, CD8A, DAO, IL1B, INS, LYZ, PKM, PLA2G12A, TNF, VEGFA
[Isoform 2]: Secreted 1 CD8A
Extracellular side 1 DAO
anchoring junction 1 ALB
transcription regulator complex 1 RARA
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 PML
external side of plasma membrane 4 ANXA5, CD8A, ITGAM, TNF
Extracellular vesicle 1 PKM
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 RARA
Z disc 1 DMD
nucleolus 2 PML, RARA
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 PKM
postsynaptic membrane 1 DMD
Cell membrane, sarcolemma 1 DMD
Mitochondrion inner membrane 1 CRLS1
Membrane raft 3 DMD, ITGAM, TNF
Cytoplasm, cytoskeleton 1 DMD
focal adhesion 1 ANXA5
extracellular matrix 1 VEGFA
Peroxisome 1 DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
Nucleus, PML body 1 PML
PML body 1 PML
collagen-containing extracellular matrix 2 ANXA5, PKM
secretory granule 2 IL1B, VEGFA
lateral plasma membrane 1 ATP2B1
Nucleus outer membrane 1 DMD
nuclear outer membrane 1 DMD
Postsynaptic cell membrane 1 DMD
receptor complex 1 CD8A
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 ALB
cilium 1 PKM
chromatin 1 RARA
cell projection 2 ATP2B1, DAO
phagocytic cup 1 TNF
cytoskeleton 1 DMD
centriole 1 ALB
Secreted, extracellular space 1 DAO
spindle pole 1 ALB
chromosome, telomeric region 1 PML
blood microparticle 1 ALB
Basolateral cell membrane 1 ATP2B1
endosome lumen 1 INS
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Presynaptic cell membrane 1 ATP2B1
filopodium membrane 1 DMD
plasma membrane raft 2 CD8A, ITGAM
ficolin-1-rich granule lumen 1 PKM
secretory granule lumen 2 INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
nuclear matrix 1 PML
platelet alpha granule lumen 2 ALB, VEGFA
voltage-gated calcium channel complex 1 CACNA1I
specific granule lumen 2 DAO, LYZ
tertiary granule lumen 1 LYZ
transport vesicle 1 INS
Secreted, extracellular exosome 1 IL1B
azurophil granule lumen 1 LYZ
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 DMD
vesicle membrane 1 ANXA5
costamere 1 DMD
[Isoform 1]: Cell membrane 1 CD8A
dystrophin-associated glycoprotein complex 1 DMD
Rough endoplasmic reticulum 1 PKM
cell-substrate junction 1 DMD
integrin complex 1 ITGAM
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD8A
integrin alphaM-beta2 complex 1 ITGAM
neuron projection terminus 1 DMD
endothelial microparticle 1 ANXA5
photoreceptor ribbon synapse 1 ATP2B1
syntrophin complex 1 DMD
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
organelle 1 DMD
plasma membrane bounded cell projection 1 DMD


文献列表

  • Marie T Thébault, Nelly Kervarec, Roger Pichon, Guy Nonnotte, Yves Le Gal. Distribution and potential role of cytosolic water-soluble phosphodiesters in fish. Physiological and biochemical zoology : PBZ. 2003 Jul; 76(4):553-65. doi: 10.1086/376424. [PMID: 13130434]
  • D C Jackson, S J Warburton, E A Meinertz, R G Lawler, J S Wasser. The effect of prolonged anoxia at 3 degrees C on tissue high energy phosphates and phosphodiesters in turtles: a 31P-NMR study. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 1995; 165(1):77-84. doi: 10.1007/bf00264689. [PMID: 7601958]
  • C T Burt. SEP as a major chicken kidney metabolite. The American journal of physiology. 1994 May; 266(5 Pt 2):R1720-1. doi: 10.1152/ajpregu.1994.266.5.r1720. [PMID: 8031405]
  • C T Burt, B Chen, C H Hill. 31P NMR investigation of vanadium-treated chick muscle. Biological trace element research. 1991 Nov; 31(2):193-8. doi: 10.1007/bf02990427. [PMID: 9438040]
  • J M Chalovich, M Bárány. Serine ethanolamine phosphate in avian muscular dystrophy: mechanism of accumulation in dystrophic muscle and relationship to phospholipid synthesis. Archives of biochemistry and biophysics. 1980 Feb; 199(2):615-25. doi: 10.1016/0003-9861(80)90319-7. [PMID: 6244784]
  • D D HAGERMAN, H ROSENBERG, A H ENNOR, P SCHIFF, S INOUE. THE ISOLATION AND PROPERTIES OF CHICKEN KIDNEY SERINE ETHANOLAMINE PHOSPHATE PHOSPHODIESTERASE. The Journal of biological chemistry. 1965 Mar; 240(?):1108-12. doi: . [PMID: 14284710]
  • H ROSENBERG, A H ENNOR, S SUGAI. BIOSYNTHESIS OF L-SERINE ETHANOLAMINE PHOSPHODIESTER. Nature. 1964 Jul; 203(?):410. doi: 10.1038/203410a0. [PMID: 14197386]