Stevioside (BioDeep_00000000005)

   

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate

化学式: C38H60O18 (804.3779460000001)
中文名称: 甜菊苷, 甜菊糖
谱图信息: 最多检出来源 Viridiplantae(plant) 0.5%

Reviewed

Last reviewed on 2024-08-26.

Cite this Page

Stevioside. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/stevioside (retrieved 2024-09-08) (BioDeep RN: BioDeep_00000000005). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C=C1CC23CCC4C(C)(C(=O)OC5OC(CO)C(O)C(O)C5O)CCCC4(C)C2CCC1(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O)C3
InChI: InChI=1S/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+/m1/s1

描述信息

Stevioside is a diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. It has a role as a sweetening agent, an antioxidant, an antineoplastic agent, a hypoglycemic agent, an anti-inflammatory agent and a plant metabolite. It is a diterpene glycoside, an ent-kaurane diterpenoid, a beta-D-glucoside, a tetracyclic diterpenoid and a bridged compound. It is functionally related to a steviol and a rubusoside.
Stevioside is a natural product found in Asteraceae, Stevia rebaudiana, and Bos taurus with data available.
See also: Stevia rebaudiuna Leaf (part of).
Stevioside is a constituent of Stevia rebaudiana (stevia). Sweetening agent which is 300 times sweeter than sucrose. Stevia rebaudiana is extensively cultivated in Japan, and Stevioside is a permitted sweetener in that country Rebaudioside B, D, and E may also be present in minute quantities; however, it is suspected that rebaudioside B is a byproduct of the isolation technique. The two majority compounds stevioside and rebaudioside, primarily responsible for the sweet taste of stevia leaves, were first isolated by two French chemists in 1931
A diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America.
Constituent of Stevia rebaudiana (stevia). Sweetening agent which is 300 times sweeter than sucrose. Stevia rebaudiana is extensively cultivated in Japan, and Stevioside is a permitted sweetener in that country
D000074385 - Food Ingredients > D005503 - Food Additives
D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents
Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana, with anticancer activity[1].
Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana, with anticancer activity[1].

Stevioside. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=57817-89-7 (retrieved 2024-08-26) (CAS RN: 57817-89-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

45 个代谢物同义名

(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-dimethyl-methylene-[?]carboxylate; 1-O-{(5beta,8alpha,9beta,10alpha,13alpha)-13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxokaur-16-en-18-yl}-beta-D-glucopyranose; 1-O-{13alpha-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl}-beta-D-glucopyranose; 1-O-(13alpha-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; KAUR-16-EN-18-OIC ACID, 13-((2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-, .BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-; (4.ALPHA.)-13-((2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID .BETA.-D-GLUCOPYRANOSYL ESTER; KAUR-16-EN-18-OIC ACID, 13-((2-O-beta-D-GLUCOPYRANOSYL-beta-D-GLUCOPYRANOSYL)OXY)-, beta-D-GLUCOPYRANOSYL ESTER, (4alpha)-; 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid, (4alpha)-beta-D-glucopyranosyl ester; (4alpha)-13-((2-O-beta-D-GLUCOPYRANOSYL-beta-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID beta-D-GLUCOPYRANOSYL ESTER; 13-[(2-O-.beta.-D-Glucopyranosyl-.alpha.-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid .beta.-D-glucopyranosyl ester; 13-((2-O-.beta.-D-Glucopyranosyl-.alpha.-D-glucopyranosyl)oxy)kaur-16-en-18-oic acid .beta.-D-glucopyranosyl ester; Kaur-16-en-18-oic acid, 13-((2-O-beta-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy)-, beta-D-glucopyranosyl ester; 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oic acid beta-D-glucopyranosyl ester; 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid beta-D-glucopyranosyl ester; Kaur-16-en-18-oic acid,13-[(2-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-,b-D-glucopyranosyl ester, (4a)-; (4alpha)-beta-D-Glucopyranosyl 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oate; 13-[(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]kaur-16-en-18-Oate beta-D-glucopyranosyl ester; 13-[(2-O-Β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-Oic acid β-D-glucopyranosyl ester; 13-[(2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]kaur-16-en-18-Oic acid b-D-glucopyranosyl ester; 13-[(2-O-Β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-Oate β-D-glucopyranosyl ester; 13-[(2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]kaur-16-en-18-Oate b-D-glucopyranosyl ester; 4-17-00-03618 (Beilstein Handbook Reference); UEDUENGHJMELGK-HYDKPPNVSA-N; STEVIOSIDE (USP-RS); Diterpene glycoside; STEVIOSIDE [USP-RS]; STEVIOSIDE (MART.); STEVIOSIDE [MART.]; steviol glycoside; STEVIOSIDE [INCI]; UNII-0YON5MXJ9P; STEVIOSIDE [MI]; .ALPHA.-G-SWEET; (-)-STEVIOSIDE; 1,2-Stevioside; alpha-G-SWEET; STEVIBIOSIDE; 0YON5MXJ9P; STEVIAN 50; Stevioside; Eupatorin?; Steviosin; Rebaudin; Stevin?



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(1)

代谢反应

63 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(63)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

53 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Joanna Śniegowska, Anita Biesiada, Alan Gasiński. Influence of the Nitrogen Fertilization on the Yield, Biometric Characteristics and Chemical Composition of Stevia rebaudiana Bertoni Grown in Poland. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081865. [PMID: 38675686]
  • Shan Li, Shuangshuang Luo, Xingying Zhao, Song Gao, Xiaoyu Shan, Jian Lu, Jingwen Zhou. Efficient Conversion of Stevioside to Rebaudioside M in Saccharomyces cerevisiae by a Engineering Hydrolase System and Prolonging the Growth Cycle. Journal of agricultural and food chemistry. 2024 Apr; 72(14):8140-8148. doi: 10.1021/acs.jafc.4c01483. [PMID: 38563232]
  • Mei-Li Xu, Yuanxin Cheng, Mo Feng, Qingguo Lu, Yunhe Lian. Identifying Potential Sources of Phthalate Contamination in the Leaves of Stevia Rebaudiana (Bertoni) and the Development of Removal Technology. Molecules (Basel, Switzerland). 2024 Apr; 29(7):. doi: 10.3390/molecules29071627. [PMID: 38611906]
  • Xiuqiong Zhang, Tiantian Chen, Zaifang Li, Xinxin Wang, Han Bao, Chunxia Zhao, Xinjie Zhao, Xin Lu, Guowang Xu. Fine-Scale Characterization of Plant Diterpene Glycosides Using Energy-Resolved Untargeted LC-MS/MS Metabolomics Analysis. Journal of the American Society for Mass Spectrometry. 2024 Mar; 35(3):603-612. doi: 10.1021/jasms.3c00420. [PMID: 38391322]
  • Samuel Simoni, Alberto Vangelisti, Clarissa Clemente, Gabriele Usai, Marco Santin, Maria Ventimiglia, Flavia Mascagni, Lucia Natali, Luciana G Angelini, Andrea Cavallini, Silvia Tavarini, Tommaso Giordani. Transcriptomic Analyses Reveal Insights into the Shared Regulatory Network of Phenolic Compounds and Steviol Glycosides in Stevia rebaudiana. International journal of molecular sciences. 2024 Feb; 25(4):. doi: 10.3390/ijms25042136. [PMID: 38396813]
  • Jakub Michał Kurek, Joanna Mikołajczyk-Stecyna, Zbigniew Krejpcio. Steviol glycosides from Stevia rebaudiana Bertoni mitigate lipid metabolism abnormalities in diabetes by modulating selected gene expression - An in vivo study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Oct; 166(?):115424. doi: 10.1016/j.biopha.2023.115424. [PMID: 37677968]
  • Agata Ptak, Agnieszka Szewczyk, Magdalena Simlat, Alicja Błażejczak, Marzena Warchoł. Meta-Topolin-induced mass shoot multiplication and biosynthesis of valuable secondary metabolites in Stevia rebaudiana Bertoni bioreactor culture. Scientific reports. 2023 09; 13(1):15520. doi: 10.1038/s41598-023-42619-8. [PMID: 37726319]
  • Pritom Biswas, Ankita Kumari, Arpan Modi, Nitish Kumar. Improvement and Regulation of Steviol Glycoside Biosynthesis in Stevia rebaudiana Bertoni. Gene. 2023 Sep; ?(?):147809. doi: 10.1016/j.gene.2023.147809. [PMID: 37722610]
  • Yu Wang, Peiyu Xu, Wenxia Wang, Xiaochen Jia, Liping Zhu, Heng Yin. Oligosaccharides increased both leaf biomass and steviol glycosides content of Stevia rebaudiana. Plant physiology and biochemistry : PPB. 2023 Aug; 202(?):107937. doi: 10.1016/j.plaphy.2023.107937. [PMID: 37566994]
  • Muhammad Arslan Ahmad, Sadaf Chaudhary, Xu Deng, Mumtaz Cheema, Rabia Javed. Nano-stevia interaction: Past, present, and future. Plant physiology and biochemistry : PPB. 2023 Aug; 201(?):107807. doi: 10.1016/j.plaphy.2023.107807. [PMID: 37311291]
  • Takehiro Watanabe, Kohki Fujikawa, Soichiro Urai, Kazunari Iwaki, Tadayoshi Hirai, Katsuro Miyagawa, Hiroshi Uratani, Tohru Yamagaki, Koji Nagao, Yoshiaki Yokoo, Keiko Shimamoto. Identification, Chemical Synthesis, and Sweetness Evaluation of Rhamnose or Xylose Containing Steviol Glycosides of Stevia (Stevia rebaudiana) Leaves. Journal of agricultural and food chemistry. 2023 Jul; ?(?):. doi: 10.1021/acs.jafc.3c01753. [PMID: 37432401]
  • Yuping Li, Yuan Qiu, Xin Xu, Ming Luo. Genome-wide identification of SrbHLH transcription factors highlights its potential role in rebaudioside A (RA) biosynthesis in Stevia rebaudiana. BMC plant biology. 2023 Jul; 23(1):352. doi: 10.1186/s12870-023-04353-1. [PMID: 37415121]
  • Krishnagowdu Saravanan, Nandakumar Vidya, Jayachandran Halka, Ravichandran Priyanka Preethi, Chinnaswamy Appunu, Ramalingam Radhakrishnan, Muthukrishnan Arun. Exogenous application of stevioside enhances root growth promotion in soybean (Glycine max (L.) Merrill). Plant physiology and biochemistry : PPB. 2023 Jul; 201(?):107881. doi: 10.1016/j.plaphy.2023.107881. [PMID: 37437344]
  • Yunxiang Bai, Beibei Liu, Jiachen Li, Minghui Li, Zheng Yao, Liangliang Dong, Dewei Rao, Peng Zhang, Xingzhong Cao, Luis Francisco Villalobos, Chunfang Zhang, Quan-Fu An, Menachem Elimelech. Microstructure optimization of bioderived polyester nanofilms for antibiotic desalination via nanofiltration. Science advances. 2023 May; 9(18):eadg6134. doi: 10.1126/sciadv.adg6134. [PMID: 37146143]
  • Vasile Coman, Violeta-Florina Scurtu, Cristina Coman, Doina Clapa, Ștefania D Iancu, Nicolae Leopold, Loredana-Florina Leopold. Effects of polystyrene nanoplastics exposure on in vitro-grown Stevia rebaudiana plants. Plant physiology and biochemistry : PPB. 2023 Apr; 197(?):107634. doi: 10.1016/j.plaphy.2023.03.011. [PMID: 36965317]
  • Alireza S Tehranian, Hossein Askari, Hassan Rezadoost. The effect of alginate as an elicitor on transcription of steviol glycosides biosynthesis pathway related key genes and sweeteners content in in vitro cultured Stevia rebaudiana. Molecular biology reports. 2023 Mar; 50(3):2283-2291. doi: 10.1007/s11033-022-07906-z. [PMID: 36576674]
  • Dariush Ramezan, Yusuf Farrokhzad, Ali Mokhtassi-Bidgoli, Mojtaba Rasouli-Alamuti. Multi-walled carbon nanotubes interact with light intensity to affect morpho-biochemical, nutrient uptake, DNA damage, and secondary metabolism of Stevia rebaudiana. Environmental science and pollution research international. 2023 Mar; 30(13):36915-36927. doi: 10.1007/s11356-022-24757-0. [PMID: 36550247]
  • Tulay Ozcan, Ezgi Eroglu. In vitro fermentation assay on the bifidogenic effect of steviol glycosides of Stevia rebaudiana plant for the development of dietetic novel products. Preparative biochemistry & biotechnology. 2023 Jan; ?(?):1-10. doi: 10.1080/10826068.2023.2169935. [PMID: 36709420]
  • Nazima Nasrullah, Javed Ahmad, Monica Saifi, Irum Gul Shah, Umara Nissar, Syed Naved Quadri, Kudsiya Ashrafi, Malik Zainul Abdin. Enhancement of diterpenoid steviol glycosides by co-overexpressing SrKO and SrUGT76G1 genes in Stevia rebaudiana Bertoni. PloS one. 2023; 18(2):e0260085. doi: 10.1371/journal.pone.0260085. [PMID: 36745615]
  • Vartika Srivastava, Rakhi Chaturvedi. An interdisciplinary approach towards sustainable and higher steviol glycoside production from in vitro cultures of Stevia rebaudiana. Journal of biotechnology. 2022 Nov; 358(?):76-91. doi: 10.1016/j.jbiotec.2022.08.018. [PMID: 36075450]
  • Sherien H Abdallah, Nada M Mostafa, Marwa Abd El Hameed Mohamed, Ahmed S Nada, Abdel Nasser B Singab. UPLC-ESI-MS/MS profiling and hepatoprotective activities of Stevia leaves extract, butanol fraction and stevioside against radiation-induced toxicity in rats. Natural product research. 2022 Nov; 36(21):5619-5625. doi: 10.1080/14786419.2021.2015594. [PMID: 34894905]
  • Ashraf Elsayed, Amal M Abdelsattar, Yasmin M Heikal, Mohamed A El-Esawi. Synergistic effects of Azospirillum brasilense and Bacillus cereus on plant growth, biochemical attributes and molecular genetic regulation of steviol glycosides biosynthetic genes in Stevia rebaudiana. Plant physiology and biochemistry : PPB. 2022 Oct; 189(?):24-34. doi: 10.1016/j.plaphy.2022.08.016. [PMID: 36041365]
  • Christos Velesiotis, Marinos Kanellakis, Demitrios H Vynios. Steviol glycosides affect functional properties and macromolecular expression of breast cancer cells. IUBMB life. 2022 10; 74(10):1012-1028. doi: 10.1002/iub.2669. [PMID: 36054915]
  • Muhammad Arslan Ahmad, Xu Deng, Muhammad Adeel, Muhammad Rizwan, Noman Shakoor, Yuesuo Yang, Rabia Javed. Influence of calcium and magnesium elimination on plant biomass and secondary metabolites of Stevia rebaudiana Bertoni. Biotechnology and applied biochemistry. 2022 Oct; 69(5):2008-2016. doi: 10.1002/bab.2263. [PMID: 34605559]
  • Miey Park, Hana Baek, Jin-Young Han, Hae-Jeung Lee. Stevioside Enhances the Anti-Adipogenic Effect and β-Oxidation by Activating AMPK in 3T3-L1 Cells and Epididymal Adipose Tissues of db/db Mice. Cells. 2022 03; 11(7):. doi: 10.3390/cells11071076. [PMID: 35406641]
  • Nikos Iatridis, Anastasia Kougioumtzi, Katerina Vlataki, Styliani Papadaki, Angeliki Magklara. Anti-Cancer Properties of Stevia rebaudiana; More than a Sweetener. Molecules (Basel, Switzerland). 2022 Feb; 27(4):. doi: 10.3390/molecules27041362. [PMID: 35209150]
  • Karel Vives Hernández, Jordi Moreno-Romero, Martha Hernández de la Torre, Claudia Pérez Manríquez, Darcy Ríos Leal, Jaime F Martínez-Garcia. Effect of light intensity on steviol glycosides production in leaves of Stevia rebaudiana plants. Phytochemistry. 2022 Feb; 194(?):113027. doi: 10.1016/j.phytochem.2021.113027. [PMID: 34861537]
  • Narendren Rengasamy, Rofina Y Othman, Hang S Che, Jennifer A Harikrishna. Beyond the PAR spectra: impact of light quality on the germination, flowering, and metabolite content of Stevia rebaudiana (Bertoni). Journal of the science of food and agriculture. 2022 Jan; 102(1):299-311. doi: 10.1002/jsfa.11359. [PMID: 34091912]
  • Marcela Hollá, Dalibor Šatínský, František Švec, Hana Sklenářová. UHPLC coupled with charged aerosol detector for rapid separation of steviol glycosides in commercial sweeteners and extract of Stevia rebaudiana. Journal of pharmaceutical and biomedical analysis. 2022 Jan; 207(?):114398. doi: 10.1016/j.jpba.2021.114398. [PMID: 34626939]
  • Esra Dandin, Ünsal Veli Üstündağ, İsmail Ünal, Perihan Seda Ateş-Kalkan, Derya Cansız, Merih Beler, Esin Ak, A Ata Alturfan, Ebru Emekli-Alturfan. Stevioside ameliorates hyperglycemia and glucose intolerance, in a diet-induced obese zebrafish model, through epigenetic, oxidative stress and inflammatory regulation. Obesity research & clinical practice. 2022 Jan; 16(1):23-29. doi: 10.1016/j.orcp.2022.01.002. [PMID: 35031270]
  • Jin-A Ko, So-Yeon Kim, Hye-Soo Ahn, Jae-Gyune Go, Young-Bae Ryu, Woo Song Lee, Young-Jung Wee, Jun-Seong Park, Doman Kim, Young-Min Kim. Characterization of a lactic acid bacterium-derived β-glucosidase for the production of rubusoside from stevioside. Enzyme and microbial technology. 2022 Jan; 153(?):109939. doi: 10.1016/j.enzmictec.2021.109939. [PMID: 34798448]
  • Dumas G Oviedo-Pereira, Melina López-Meyer, Silvia Evangelista-Lozano, Luis G Sarmiento-López, Gabriela Sepúlveda-Jiménez, Mario Rodríguez-Monroy. Enhanced specialized metabolite, trichome density, and biosynthetic gene expression in Stevia rebaudiana (Bertoni) Bertoni plants inoculated with endophytic bacteria Enterobacter hormaechei. PeerJ. 2022; 10(?):e13675. doi: 10.7717/peerj.13675. [PMID: 35782100]
  • Şemsi Gül Yılmaz, Aslı Uçar, Serkan Yılmaz. Do steviol glycosides affect the oxidative and genotoxicity parameters in BALB/c mice?. Drug and chemical toxicology. 2022 Jan; 45(1):464-469. doi: 10.1080/01480545.2020.1716000. [PMID: 31959022]
  • Nisar Ahmad, Palwasha Khan, Abdullah Khan, Maliha Usman, Mohammad Ali, Hina Fazal, Durrishahwar, Muhammad Nazir Uddin, Christophe Hano, Bilal Haider Abbasi. Elicitation of Submerged Adventitious Root Cultures of Stevia rebaudiana with Cuscuta reflexa for Production of Biomass and Secondary Metabolites. Molecules (Basel, Switzerland). 2021 Dec; 27(1):. doi: 10.3390/molecules27010014. [PMID: 35011247]
  • Abilasha Deenadayalan, Vijayalakshmi Subramanian, Vijayalakshmi Paramasivan, Vishnu Priya Veeraraghavan, Gayathri Rengasamy, Janaki Coiambatore Sadagopan, Ponnulakshmi Rajagopal, Selvaraj Jayaraman. Stevioside Attenuates Insulin Resistance in Skeletal Muscle by Facilitating IR/IRS-1/Akt/GLUT 4 Signaling Pathways: An In Vivo and In Silico Approach. Molecules (Basel, Switzerland). 2021 Dec; 26(24):. doi: 10.3390/molecules26247689. [PMID: 34946771]
  • Jinzhu Zhang, Minghai Tang, Yujie Chen, Dan Ke, Jie Zhou, Xinyu Xu, Wenxian Yang, Jianxiong He, Haohao Dong, Yuquan Wei, James H Naismith, Yi Lin, Xiaofeng Zhu, Wei Cheng. Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nature communications. 2021 12; 12(1):7030. doi: 10.1038/s41467-021-27144-4. [PMID: 34857750]
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