1,2-Benzoquinone (BioDeep_00000004903)

 

Secondary id: BioDeep_00001868744

human metabolite Endogenous


代谢物信息卡片


3,5-Cyclohexadiene-1,2-dione (9ci)

化学式: C6H4O2 (108.0211)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 20.49%

分子结构信息

SMILES: C1=CC(=O)C(=O)C=C1
InChI: InChI=1S/C6H4O2/c7-5-3-1-2-4-6(5)8/h1-4H

描述信息

1,2-Benzoquinone is a reactive electrophile that is an intermediate in benzene metabolism. It is substrate for the enzyme Catechol oxidase (EC 1.10.3.1) and can be generated from the oxidation of catechol. 1,2-Benzoquinone is capable of reacting with blood proteins to produce adducts.
1,2-Benzoquinone, also called ortho-benzoquinone or cyclohexa-3,5-diene-1,2-dione, is a ketone, with formula C6H4O2. It is one of the two isomers of quinone, the other being 1,4-benzoquinone. O-Quinone is found in tea.

同义名列表

12 个代谢物同义名

3,5-Cyclohexadiene-1,2-dione (9ci); Cyclohexa-3,5-diene-1,2-dione; 3,5-Cyclohexadiene-1,2-dione; Ortho-benzoquinone; benzo-1,2-Quinone; Catechol quinone; 1,2-Benzoquinone; 2-Benzoquinone; O-Benzoquinone; Benzoquinone; O-Quinone; o-Benzoquinone



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

102 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(100)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AHR, AKR1C4, AOC3, CAT, CYP2D6, CYP2E1, HPGDS, KEAP1, NQO1, TYR
Peripheral membrane protein 3 CYP1B1, CYP2E1, HSD17B6
Endoplasmic reticulum membrane 3 CYP1B1, CYP2D6, CYP2E1
Nucleus 4 AHR, KEAP1, NQO1, OGG1
cytosol 10 AHR, AKR1A1, AKR1C1, AKR1C4, CAT, COMT, HPGDS, KEAP1, NQO1, OGG1
dendrite 2 COMT, NQO1
nucleoplasm 4 AHR, HPGDS, KEAP1, OGG1
Cell membrane 2 AOC3, COMT
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 2 MT-CYB, SLC45A2
Synapse 3 AKR1A1, COMT, NQO1
cell surface 1 AOC3
Golgi apparatus 1 AOC3
mitochondrial inner membrane 2 CYP2E1, MT-CYB
neuronal cell body 1 NQO1
Cytoplasm, cytosol 4 AKR1A1, AKR1C1, AKR1C4, NQO1
Lysosome 1 TYR
plasma membrane 2 AOC3, COMT
Membrane 8 AOC3, CAT, COMT, CYP1B1, CYP2D6, MT-CYB, NQO1, SLC45A2
apical plasma membrane 1 AKR1A1
axon 1 COMT
extracellular exosome 5 AKR1A1, AKR1C1, AKR1C4, CAT, COMT
Lumenal side 1 HSD17B6
endoplasmic reticulum 4 AOC3, CYP2D6, HSD17B6, KEAP1
extracellular space 2 AKR1A1, LOX
perinuclear region of cytoplasm 1 TYR
mitochondrion 5 CAT, CYP1B1, CYP2D6, MT-CYB, OGG1
protein-containing complex 3 AHR, CAT, OGG1
intracellular membrane-bounded organelle 8 CAT, COMT, CYP1B1, CYP2D6, CYP2E1, HPGDS, HSD17B6, TYR
Microsome membrane 4 CYP1B1, CYP2D6, CYP2E1, HSD17B6
Single-pass type I membrane protein 1 TYR
Secreted 1 LOX
extracellular region 2 CAT, LOX
Single-pass membrane protein 1 CYP2D6
mitochondrial matrix 2 CAT, OGG1
Extracellular side 1 COMT
transcription regulator complex 1 AHR
centriolar satellite 1 KEAP1
Melanosome membrane 2 SLC45A2, TYR
midbody 1 KEAP1
Early endosome 1 AOC3
Golgi-associated vesicle 1 TYR
Single-pass type II membrane protein 2 AOC3, COMT
Apical cell membrane 1 AKR1A1
Mitochondrion inner membrane 2 CYP2E1, MT-CYB
focal adhesion 1 CAT
extracellular matrix 1 LOX
Peroxisome 1 CAT
collagen trimer 1 LOX
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 LOX
nuclear speck 1 OGG1
chromatin 1 AHR
Secreted, extracellular space 1 LOX
actin filament 1 KEAP1
Cul3-RING ubiquitin ligase complex 1 KEAP1
microvillus 1 AOC3
aryl hydrocarbon receptor complex 1 AHR
Nucleus, nucleoplasm 1 OGG1
Melanosome 1 TYR
Nucleus speckle 1 OGG1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
nuclear matrix 1 OGG1
Nucleus matrix 1 OGG1
respiratory chain complex III 1 MT-CYB
catalase complex 1 CAT
inclusion body 1 KEAP1
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR


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