Juglone (BioDeep_00000000449)

 

Secondary id: BioDeep_00000867266

human metabolite PANOMIX_OTCML-2023 Endogenous Volatile Flavor Compounds


代谢物信息卡片


InChI=1/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12

化学式: C10H6O3 (174.03169259999999)
中文名称: 胡桃醌, 5-羟基对萘醌, 5-羟基-p-萘醌
谱图信息: 最多检出来源 Viridiplantae(plant) 0.06%

分子结构信息

SMILES: C1=CC2=C(C(=O)C=CC2=O)C(=C1)O
InChI: InChI=1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H

描述信息

Juglone is a hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities. It has a role as a herbicide, a reactive oxygen species generator and a geroprotector.
Juglone is a natural product found in Talaromyces diversus, Carya alba, and other organisms with data available.
Occurs in Juglans subspecies and pecan nuts (Carya illinoensis). Juglone is found in many foods, some of which are common walnut, liquor, black walnut, and nuts.
Juglone is found in black walnut. Juglone occurs in Juglans species and pecan nuts (Carya illinoensis
D000074385 - Food Ingredients > D005503 - Food Additives > D005520 - Food Preservatives
D009676 - Noxae > D003603 - Cytotoxins
D000970 - Antineoplastic Agents
D004791 - Enzyme Inhibitors

同义名列表

75 个代谢物同义名

InChI=1/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12; 4-08-00-02368 (Beilstein Handbook Reference); 1,4-dihydro-1,4-dioxo-5-hydroxynaphthalene; 5-hydroxy-1,4-dihydronaphthalene-1,4-dione; 5-Hydroxy-1,4-naphthalenedione, 9CI; 5-Hydroxy-1,4-naphthoquinone, 97\\%; 5-Hydroxy-1,4-naftochinon [Czech]; 1,4-NAPHTHALENEDIONE, 5-HYDROXY-; 5-Hydroxy-1,4-naphthosemiquinone; 5-hydroxy-naphthalene-1,4-dione; 5-hydroxy-1,4-naphthoquinone, 4; 1,4-Naphthoquinone, 8-hydroxy-; 5-Hydroxy-1,4-naphthalenedione; 5-Hydroxynaphthalene-1,4-dione; 1,4-Naphthoquinone, 5-hydroxy-; 8-Hydroxy-1,4-naphthalenedione; 5-Hydroxy-[1,4]Naphthoquinone; -Hydroxy-1,4-naphthalenedione; 8-Hydroxy-1,4-naphthoquinone; 5-hydroxy-1,4-naphthoquinone; 5-Hydroxy-p-naphthoquinone; 5-Hydroxy-1,4-naftochinon; 5-Hydroxynaphthoquinone; JUGLONE CRYSTALLIZED; C.I. Natural Brown 7; WLN: L66 BV EVJ GQ; Spectrum5_000357; Spectrum2_000778; Spectrum4_001769; Spectrum3_001228; UNII-W6Q80SK9L6; walnut extract; Antibiotic PD7; 1, 8-hydroxy-; DivK1c_001026; KBio1_001026; KBio2_003463; KBio3_000914; KBio2_005038; KBio3_002948; KBio2_006031; KBio2_002470; KBio2_007606; JUGLONE [MI]; KBio2_005633; KBio2_000895; KBio3_000913; KBio2_000497; KBio3_002176; KBio2_003065; IDI1_001026; IDI1_002164; SMP1_000168; Bio2_000409; Bio1_001419; Bio1_000441; Bio2_000889; Bio1_000930; W6Q80SK9L6; CI 75500; Regianin; Juglone; Jugnlon; Juglane; Lawsone; Yuglon; Juglon; Iuglon; Akhnot; 5-HNQ; Nucin; 3b7j; PD7; Juglone; Juglone



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(5)

PlantCyc(4)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nina V Terletskaya, Elvira A Shadenova, Yuliya A Litvinenko, Kazhybek Ashimuly, Malika Erbay, Aigerim Mamirova, Irada Nazarova, Nataliya D Meduntseva, Nataliya O Kudrina, Nazym K Korbozova, Erika D Djangalina. Influence of Cold Stress on Physiological and Phytochemical Characteristics and Secondary Metabolite Accumulation in Microclones of Juglans regia L. International journal of molecular sciences. 2024 May; 25(9):. doi: 10.3390/ijms25094991. [PMID: 38732208]
  • Yukie Akutsu, Takaaki Fujiwara, Rintaro Suzuki, Yuki Nishigaya, Toshimasa Yamazaki. Juglone, a plant-derived 1,4-naphthoquinone, binds to hydroxylamine oxidoreductase and inhibits the electron transfer to cytochrome c554. Applied and environmental microbiology. 2023 Dec; 89(12):e0129123. doi: 10.1128/aem.01291-23. [PMID: 38009977]
  • Pei-Ling Yen, Ting-An Lin, Wei Lin Chuah, Chih-Yi Chang, Yen-Hsueh Tseng, Chia-Yin Huang, Jeng-Chuann Yang, Fu-Lan Hsu, Vivian Hsiu-Chuan Liao. Methanol Extracts from Cirsium japonicum DC. var. australe Kitam. and Their Active Components Reduce Intracellular Oxidative Stress in Caenorhabditis elegans. Molecules (Basel, Switzerland). 2023 Oct; 28(19):. doi: 10.3390/molecules28196923. [PMID: 37836767]
  • Sara Thabit, Heba Handoussa, Nesrine S ElSayed, Hans-Georg Breitinger, Ulrike Breitinger, Michael Wink. A fruit extract of Styphnolobium japonicum (L.) counteracts oxidative stress and mediates neuroprotection in Caenorhabditis elegans. BMC complementary medicine and therapies. 2023 Sep; 23(1):330. doi: 10.1186/s12906-023-04149-8. [PMID: 37726773]
  • Leeladarshini Sujeeun, Sean C Thomas. Biochar mitigates allelopathic effects in temperate trees. Ecological applications : a publication of the Ecological Society of America. 2023 06; 33(4):e2832. doi: 10.1002/eap.2832. [PMID: 36864680]
  • Kaihua Wang, Beibei Wang, Henan Ma, Ziwen Wang, Yuxiu Liu, Qingmin Wang. Natural Products for Pesticides Discovery: Structural Diversity Derivation and Biological Activities of Naphthoquinones Plumbagin and Juglone. Molecules (Basel, Switzerland). 2023 Apr; 28(8):. doi: 10.3390/molecules28083328. [PMID: 37110562]
  • Weijia Chen, Lei He, Hongyan Pei, Jianming Li, Yan Zhao, Ying Zong, Hong Kan, Zhongmei He, Rui Du. Neuroprotective effect of total flavonoids in stems and leaves of Glycyrrhiza uralensis Fisch. on oxidative stress in HT-22 cells and Caenorhabditis elegans. Aging. 2023 Apr; 15(12):5290-5303. doi: 10.18632/aging.204627. [PMID: 37367832]
  • Beatrycze Nowicka, Jan Walczak, Maja Kapsiak, Karolina Barnaś, Julia Dziuba, Aleksandra Suchoń. Impact of cytotoxic plant naphthoquinones, juglone, plumbagin, lawsone and 2-methoxy-1,4-naphthoquinone, on Chlamydomonas reinhardtii reveals the biochemical mechanism of juglone toxicity by rapid depletion of plastoquinol. Plant physiology and biochemistry : PPB. 2023 Apr; 197(?):107660. doi: 10.1016/j.plaphy.2023.107660. [PMID: 36996637]
  • Wu-Heng Yue, Lan-Qun Qin, Juan Cai, Rui Mei, Han-Qing Qian, Zheng-Yun Zou. Jug-PLGA-NPs, a New Form of Juglone with Enhanced Efficiency and Reduced Toxicity on Melanoma. Chinese journal of integrative medicine. 2022 Oct; 28(10):909-917. doi: 10.1007/s11655-021-3461-y. [PMID: 34913148]
  • Xiang Li, Kewei Cai, Qinhui Zhang, Xiaona Pei, Song Chen, Luping Jiang, Zhiming Han, Minghui Zhao, Yan Li, Xinxin Zhang, Yuxi Li, Shikai Zhang, Su Chen, Guanzheng Qu, Mulualem Tigabu, Vincent L Chiang, Ronald Sederoff, Xiyang Zhao. The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis. GigaScience. 2022 06; 11(?):. doi: 10.1093/gigascience/giac057. [PMID: 35764602]
  • Muhammad Furqan, Alishba Fayyaz, Farhat Firdous, Hadeeqa Raza, Aishah Bilal, Rahman Shah Zaib Saleem, Syed Shahzad-Ul-Hussan, Daijie Wang, Fadia S Youssef, Nawal M Al Musayeib, Mohamed L Ashour, Hidayat Hussain, Amir Faisal. Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors. Journal of natural products. 2022 06; 85(6):1503-1513. doi: 10.1021/acs.jnatprod.1c01222. [PMID: 35687347]
  • Yu Ting Tang, Yang Li, Peng Chu, Xiao Dong Ma, Ze Yao Tang, Zhao Lin Sun. Molecular biological mechanism of action in cancer therapies: Juglone and its derivatives, the future of development. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Apr; 148(?):112785. doi: 10.1016/j.biopha.2022.112785. [PMID: 35272138]
  • Jialei Mao, Yinzhu Bian, Qun Zhang, Linghui Kong, Xiao Shi, Jing Hu, Mi Yang, Li Li, Hanqing Qian, Baorui Liu, Xiaoping Qian. Antitumor activity of iRGD-modified red blood cell membrane nanoparticles loaded with Juglone and Oxaliplatin against colorectal cancer. Journal of biomaterials applications. 2022 02; 36(7):1301-1316. doi: 10.1177/08853282211052386. [PMID: 34802305]
  • Falak Niaz, Muhammad Faheem, Mutiullah Khattak, Iqra Anam Khawaja, Mi-Jeong Ahn, Umakanta Sarker, Syed Babar Jamal, Riaz Ullah, Atif Ali Khan Khalil. Antibacterial and Antibiofilm Activity of Juglone Derivatives against Enterococcus faecalis: An In Silico and In Vitro Approach. BioMed research international. 2022; 2022(?):6197375. doi: 10.1155/2022/6197375. [PMID: 36408282]
  • Qiqi Han, Luoluo Feng, Yani Zhang, Runguang Zhang, Guoliang Wang, Youlin Zhang. Effect of Juglone against Pseudomonas syringae pv Actinidiae Planktonic Growth and Biofilm Formation. Molecules (Basel, Switzerland). 2021 Dec; 26(24):. doi: 10.3390/molecules26247580. [PMID: 34946659]
  • Jiahua Cui, Jinping Jia. Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors. European journal of medicinal chemistry. 2021 Dec; 225(?):113789. doi: 10.1016/j.ejmech.2021.113789. [PMID: 34438124]
  • Qiqi Han, Xinpeng Yan, Runguang Zhang, Guoliang Wang, Youlin Zhang. Juglone Inactivates Pseudomonas aeruginosa through Cell Membrane Damage, Biofilm Blockage, and Inhibition of Gene Expression. Molecules (Basel, Switzerland). 2021 Sep; 26(19):. doi: 10.3390/molecules26195854. [PMID: 34641398]
  • Waseem-Ul- Arifeen, Fazal-Ur- Rehman, Shahid Adeel, Muhammad Zuber, Mirza Nadeem Ahmad, Tanvir Ahmad. Environmental friendly extraction of walnut bark-based juglone natural colorant for dyeing studies of wool fabric. Environmental science and pollution research international. 2021 Sep; 28(36):49958-49966. doi: 10.1007/s11356-021-14277-8. [PMID: 33948834]
  • Yongzhi Hua, Ruiqi Liu, Min Lu, Xueneng Guan, Suyang Zhuang, Yaozhou Tian, Zhenhai Zhang, Li Cui. Juglone regulates gut microbiota and Th17/Treg balance in DSS-induced ulcerative colitis. International immunopharmacology. 2021 Aug; 97(?):107683. doi: 10.1016/j.intimp.2021.107683. [PMID: 33915494]
  • Yuan-Yuan Zhang, Zhi-Jing Ni, Elnur Elam, Fan Zhang, Kiran Thakur, Shaoyun Wang, Jian-Guo Zhang, Zhao-Jun Wei. Juglone, a novel activator of ferroptosis, induces cell death in endometrial carcinoma Ishikawa cells. Food & function. 2021 Jun; 12(11):4947-4959. doi: 10.1039/d1fo00790d. [PMID: 34100505]
  • Bolor Tsolmon, Yang Fang, Tao Yang, Ling Guo, Kaize He, Guo-You Li, Hai Zhao. Structural identification and UPLC-ESI-QTOF-MS2 analysis of flavonoids in the aquatic plant Landoltia punctata and their in vitro and in vivo antioxidant activities. Food chemistry. 2021 May; 343(?):128392. doi: 10.1016/j.foodchem.2020.128392. [PMID: 33191012]
  • Alagesan Seetha, Halagowder Devaraj, Ganapasam Sudhandiran. Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. Life sciences. 2021 Jan; 264(?):118657. doi: 10.1016/j.lfs.2020.118657. [PMID: 33148421]
  • Xiaojie Zhao, Dan Wang, Shanshan Wan, Xiuheng Liu, Wei Wang, Lei Wang. The Suppression of Pin1-Alleviated Oxidative Stress through the p38 MAPK Pathway in Ischemia- and Reperfusion-Induced Acute Kidney Injury. Oxidative medicine and cellular longevity. 2021; 2021(?):1313847. doi: 10.1155/2021/1313847. [PMID: 34373763]
  • Xue Zhang, Changyin Zhou, Wenxiu Cheng, Ruixin Tao, Hongxia Xu, Honglin Liu. Vitamin C protects early mouse embryos against juglone toxicity. Reproductive toxicology (Elmsford, N.Y.). 2020 12; 98(?):200-208. doi: 10.1016/j.reprotox.2020.09.011. [PMID: 33010468]
  • Gisela A González-Montiel, Elizabeth N Kaweesa, Nicolas Feau, Richard C Hamelin, Jeffrey K Stone, Sandra Loesgen. Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus Zasmidium pseudotsugae. Molecules (Basel, Switzerland). 2020 May; 25(10):. doi: 10.3390/molecules25102358. [PMID: 32438585]
  • Jun-Yu Shi, Zhe Ren Huang, Hong Yan Gao, Xiao Li Xu. Anticancer effects of juglone in OVCAR-3 human ovarian carcinoma are facilitated through programmed cell death, endogenous ROS production, inhibition of cell migration and invasion and cell cycle arrest. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2020 Mar; 25(2):779-784. doi: . [PMID: 32521867]
  • Fatemeh Abyar, Leila Tabrizi. Experimental and theoretical investigations of novel oxidovanadium(IV) juglone complex: DNA/HSA interaction and cytotoxic activity. Journal of biomolecular structure & dynamics. 2020 02; 38(2):474-487. doi: 10.1080/07391102.2019.1580221. [PMID: 30831056]
  • Inés Reigada, Cristina Moliner, Marta Sofía Valero, David Weinkove, Elisa Langa, Carlota Gómez Rincón. Antioxidant and Antiaging Effects of Licorice on the Caenorhabditis elegans Model. Journal of medicinal food. 2020 Jan; 23(1):72-78. doi: 10.1089/jmf.2019.0081. [PMID: 31545123]
  • Xue Zhang, Weijian Li, Xiaofan Sun, Juan Li, Wangjun Wu, Honglin Liu. Vitamin C protects against defects induced by juglone during porcine oocyte maturation. Journal of cellular physiology. 2019 11; 234(11):19574-19581. doi: 10.1002/jcp.28555. [PMID: 30980384]
  • Qin Yang, Qing-Shou Yao, Yi Kuang, Yue-Zhi Zhang, Ling-Ling Feng, Lu Zhang, Lin Guo, Ze-Ping Xie, Shu-Min Zhang. Antimicrobial and cytotoxic juglones from the immature exocarps of Juglans mandshurica. Natural product research. 2019 Nov; 33(22):3203-3209. doi: 10.1080/14786419.2018.1468326. [PMID: 29726709]
  • Peng Wang, Sun-Dong Zhang, Jiao Jiao, Wei Wang, Liang Yu, Xue-Lian Zhao, Li-Tao Wang, Dong Meng, Yu-Jie Fu. ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro. Toxicology and applied pharmacology. 2019 09; 379(?):114647. doi: 10.1016/j.taap.2019.114647. [PMID: 31283929]
  • Panthakarn Rangsinth, Anchalee Prasansuklab, Chatrawee Duangjan, Xiaojie Gu, Krai Meemon, Michael Wink, Tewin Tencomnao. Leaf extract of Caesalpinia mimosoides enhances oxidative stress resistance and prolongs lifespan in Caenorhabditis elegans. BMC complementary and alternative medicine. 2019 Jul; 19(1):164. doi: 10.1186/s12906-019-2578-5. [PMID: 31286949]
  • Yuan-Yuan Zhang, Fan Zhang, Ying-Shuo Zhang, Kiran Thakur, Jian-Guo Zhang, Yun Liu, Huan Kan, Zhao-Jun Wei. Mechanism of Juglone-Induced Cell Cycle Arrest and Apoptosis in Ishikawa Human Endometrial Cancer Cells. Journal of agricultural and food chemistry. 2019 Jul; 67(26):7378-7389. doi: 10.1021/acs.jafc.9b02759. [PMID: 31184118]
  • Xin Fan, Huaiyu He, Jiao Li, Guoyong Luo, Yuanyuan Zheng, Jian-Kang Zhou, Juan He, Wenchen Pu, Yun Zhao. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis. Bioorganic & medicinal chemistry. 2019 06; 27(11):2235-2244. doi: 10.1016/j.bmc.2019.04.028. [PMID: 31027708]
  • Atif Ali Khan Khalil, Woo Sung Park, Jeehoon Lee, Hye-Jin Kim, Kazi-Marjahan Akter, Young-Min Goo, Ji-Yeong Bae, Man-Seog Chun, Jung-Hwan Kim, Mi-Jeong Ahn. A new anti-Helicobacter pylori juglone from Reynoutria japonica. Archives of pharmacal research. 2019 Jun; 42(6):505-511. doi: 10.1007/s12272-019-01160-x. [PMID: 31073878]
  • Satoshi Endo, Namiki Miyagi, Toshiyuki Matsunaga, Akira Ikari. Rabbit dehydrogenase/reductase SDR family member 11 (DHRS11): Its identity with acetohexamide reductase with broad substrate specificity and inhibitor sensitivity, different from human DHRS11. Chemico-biological interactions. 2019 May; 305(?):12-20. doi: 10.1016/j.cbi.2019.03.026. [PMID: 30926317]
  • Wuguo Li, Qing Zhang, Kaotan Chen, Zhenhua Sima, Jingli Liu, Qiang Yu, Jiawei Liu. 2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells. BMC complementary and alternative medicine. 2019 Feb; 19(1):38. doi: 10.1186/s12906-019-2440-9. [PMID: 30709346]
  • Hubert Sytykiewicz, Agnieszka Kozak, Bogumił Leszczyński, Cezary Sempruch, Iwona Łukasik, Iwona Sprawka, Katarzyna Kmieć, Monika Kurowska, Aldona Kopczyńska, Paweł Czerniewicz. Transcriptional profiling of catalase genes in juglone-treated seeds of maize (Zea mays L.) and wheat (Triticum aestivum L.). Acta biologica Hungarica. 2018 Dec; 69(4):449-463. doi: 10.1556/018.69.2018.4.7. [PMID: 30587016]
  • Andréia Limana Tambara, Liliana de Los Santos Moraes, Ana Helena Dal Forno, Jean Ramos Boldori, Ana Thalita Gonçalves Soares, Cristiane de Freitas Rodrigues, Lilian Regina Barros Mariutti, Adriana Zerlotti Mercadante, Daiana Silva de Ávila, Cristiane Casagrande Denardin. Purple pitanga fruit (Eugenia uniflora L.) protects against oxidative stress and increase the lifespan in Caenorhabditis elegans via the DAF-16/FOXO pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Oct; 120(?):639-650. doi: 10.1016/j.fct.2018.07.057. [PMID: 30077708]
  • Peng Wang, Chang Gao, Wei Wang, Li-Ping Yao, Jing Zhang, Sun-Dong Zhang, Ji Li, Shao-Hong Fang, Yu-Jie Fu. Juglone induces apoptosis and autophagy via modulation of mitogen-activated protein kinase pathways in human hepatocellular carcinoma cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Jun; 116(Pt B):40-50. doi: 10.1016/j.fct.2018.04.004. [PMID: 29627502]
  • Alexandra G Durán, Nuria Chinchilla, José Mg Molinillo, Francisco A Macías. Influence of lipophilicity in O-acyl and O-alkyl derivatives of juglone and lawsone: a structure-activity relationship study in the search for natural herbicide models. Pest management science. 2018 Mar; 74(3):682-694. doi: 10.1002/ps.4764. [PMID: 29024464]
  • Mansour Sobeh, Mona F Mahmoud, Mohamed A O Abdelfattah, Haroan Cheng, Assem M El-Shazly, Michael Wink. A proanthocyanidin-rich extract from Cassia abbreviata exhibits antioxidant and hepatoprotective activities in vivo. Journal of ethnopharmacology. 2018 Mar; 213(?):38-47. doi: 10.1016/j.jep.2017.11.007. [PMID: 29126990]
  • Beatrycze Nowicka, Andrzej Żądło, Bartosz Pluciński, Jerzy Kruk, Paulina Kuczyńska. The oxidative stress in allelopathy: Participation of prenyllipid antioxidants in the response to juglone in Chlamydomonas reinhardtii. Phytochemistry. 2017 Dec; 144(?):171-179. doi: 10.1016/j.phytochem.2017.09.012. [PMID: 28942064]
  • Mansour Sobeh, Mona F Mahmoud, Rehab A Hasan, Haroan Cheng, Assem M El-Shazly, Michael Wink. Senna singueana: Antioxidant, Hepatoprotective, Antiapoptotic Properties and Phytochemical Profiling of a Methanol Bark Extract. Molecules (Basel, Switzerland). 2017 Sep; 22(9):. doi: 10.3390/molecules22091502. [PMID: 28885586]
  • Pan Zhao, Guihua Gao, Lianjun Zhang, Qianqian Cai, Nan Lu, Li Cheng, Shuaikang Li, Xiaohong Hou. Drug-protein binding mechanism of juglone for early pharmacokinetic profiling: Insights from ultrafiltration, multi-spectroscopic and molecular docking methods. Journal of pharmaceutical and biomedical analysis. 2017 07; 141(?):262-269. doi: 10.1016/j.jpba.2017.03.036. [PMID: 28372900]
  • Ming Liu, Peng Yu, Hong Jiang, Xue Yang, Ji Zhao, Yunzeng Zou, Junbo Ge. The Essential Role of Pin1 via NF-κB Signaling in Vascular Inflammation and Atherosclerosis in ApoE-/- Mice. International journal of molecular sciences. 2017 Mar; 18(3):. doi: 10.3390/ijms18030644. [PMID: 28300760]
  • D Wianowska, S Garbaczewska, A Cieniecka-Roslonkiewicz, A L Dawidowicz, A Jankowska. Comparison of antifungal activity of extracts from different Juglans regia cultivars and juglone. Microbial pathogenesis. 2016 Nov; 100(?):263-267. doi: 10.1016/j.micpath.2016.10.009. [PMID: 27744101]
  • Xue Liu, Ershun Liang, Xiuhui Song, Zhanhui Du, Yun Zhang, Yuxia Zhao. Inhibition of Pin1 alleviates myocardial fibrosis and dysfunction in STZ-induced diabetic mice. Biochemical and biophysical research communications. 2016 10; 479(1):109-15. doi: 10.1016/j.bbrc.2016.09.050. [PMID: 27634219]
  • Jiayi Wang, Yuhuan Cheng, Rina Wu, Donghua Jiang, Bing Bai, Dehong Tan, Tingcai Yan, Xiyun Sun, Qi Zhang, Zhaoxia Wu. Antibacterial Activity of Juglone against Staphylococcus aureus: From Apparent to Proteomic. International journal of molecular sciences. 2016 Jun; 17(6):. doi: 10.3390/ijms17060965. [PMID: 27322260]
  • Jiayi Wang, Zixue Wang, Rina Wu, Donghua Jiang, Bing Bai, Dehong Tan, Tingcai Yan, Xiyun Sun, Qi Zhang, Zhaoxia Wu. Proteomic Analysis of the Antibacterial Mechanism of Action of Juglone against Staphylococcus aureus. Natural product communications. 2016 Jun; 11(6):825-7. doi: ". [PMID: 27534127]
  • Roongpetch Keowkase, Natthida Weerapreeyakul. Cratoxylum formosum Extract Protects against Amyloid-Beta Toxicity in a Caenorhabditis elegans Model of Alzheimer's Disease. Planta medica. 2016 Apr; 82(6):516-23. doi: 10.1055/s-0041-111621. [PMID: 26845710]
  • Soraya Sajadimajd, Razieh Yazdanparast, Fariba Roshanzamir. Augmentation of oxidative stress-induced apoptosis in MCF7 cells by ascorbate-tamoxifen and/or ascorbate-juglone treatments. In vitro cellular & developmental biology. Animal. 2016 Feb; 52(2):193-203. doi: 10.1007/s11626-015-9961-4. [PMID: 26559067]
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