Oxalate (ethanedioate) (BioDeep_00000004136)

 

Secondary id: BioDeep_00000405524

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Toxin


代谢物信息卡片


Oxalate, monohydrogen monopotassium

化学式: C2H2O4 (89.99530920000001)
中文名称: 草酸, 乙二酸, 草酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.1%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Oxalate (ethanedioate). BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/oxalate_(ethanedioate) (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000004136). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(=O)(C(=O)O)O
InChI: InChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)

描述信息

Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent (Pubchem). Oxalic acid (IUPAC name: ethanedioic acid, formula H2C2O4) is a dicarboxylic acid with structure (HOOC)-(COOH). Because of the joining of two carboxyl groups, this is one of the strongest organic acids. It is also a reducing agent. The anions of oxalic acid as well as its salts and esters are known as oxalates (Wikipedia). Bodily oxalic acid may also be synthesized via the metabolism of either glyoxylic acid or unused ascorbic acid (vitamin C), which is a serious health consideration for long term megadosers of vitamin C supplements. 80\\\\% of kidney stones are formed from calcium oxalate. Some Aspergillus species produce oxalic acid, which reacts with blood or tissue calcium to precipitate calcium oxalate. There is some preliminary evidence that the administration of probiotics can affect oxalic acid excretion rates (and presumably oxalic acid levels as well) (Wikipedia). Oxalic acid is found to be associated with fumarase deficiency and primary hyperoxaluria I, which are inborn errors of metabolism. Oxalic acid is a marker for yeast overgrowth from Aspergillus, Penicillum and/or Candida. Can also be elevated due to exposures from vitamin C or ethylene glycol poisoning. Oxalate is elevated in the urine of children with autism. (PMID: 21911305). Oxalic acid has also been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821).
Oxalic acid, also known as oxalate or ethanedioic acid, belongs to dicarboxylic acids and derivatives class of compounds. Those are organic compounds containing exactly two carboxylic acid groups. Oxalic acid is soluble (in water) and a moderately acidic compound (based on its pKa). Oxalic acid can be found in a number of food items such as grape, sacred lotus, orange mint, and date, which makes oxalic acid a potential biomarker for the consumption of these food products. Oxalic acid can be found primarily in blood, saliva, sweat, and urine, as well as throughout most human tissues. Oxalic acid exists in all living organisms, ranging from bacteria to humans. Moreover, oxalic acid is found to be associated with fumarase deficiency, glycolic aciduria, hemodialysis, and primary hyperoxaluria I. Oxalic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Oxalic acids acid strength is much greater than that of acetic acid. Oxalic acid is a reducing agent and its conjugate base, known as oxalate (C 2O2− 4), is a chelating agent for metal cations. Typically, oxalic acid occurs as the dihydrate with the formula C2H2O4·2H2O . Acute Exposure: If oxalic acid is swallowed, immediately give the person water or milk, unless instructed otherwise by a health care provider. DO NOT give water or milk if the person is having symptoms (such as vomiting, convulsions, or a decreased level of alertness) that make it hard to swallow. If acute exposure occurs to the eyes, irrigate opened eyes for several minutes under running water.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019163 - Reducing Agents
Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent.
Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent.

同义名列表

63 个代谢物同义名

Oxalate, monohydrogen monopotassium; Ammonium oxalate;Ethane-1,2-dioate; Monohydrogen monopotassium oxalate; Manganese (2+) oxalate (1:1); Chromium (3+) oxalate (3:2); Oxalic acid diammonium salt; Oxalate, potassium chromium; Potassium chromium oxalate; Ethanedioic acid dihydrate; Magnesium oxalate (1:1); Potassium oxalate (2:1); Iron (2+) oxalate (1:1); Oxalate, monopotassium; Oxalic acid 2-hydrate; Oxalic acid anhydrous; Oxalic acid dihydrate; Ethane-1,2-dioic acid; Monopotassium oxalate; Chromium (2+) oxalate; Oxalate, monoammonium; Oxalate, dipotassium; Monoammonium oxalate; Dipotassium oxalate; Oxalate, monosodium; Oxalate, diammonium; Oxalate, magnesium; Diammonium oxalate; Oxalate, potassium; Monosodium oxalate; Oxalate, dilithium; Kyselina stavelova; Oxalate, disodium; Oxalate, aluminum; Ethane-1,2-dioate; Oxalate, chromium; Iron (3+) oxalate; Potassium oxalate; Magnesium oxalate; Dilithium oxalate; Ethanedionic acid; Disodium oxalate; aluminum oxalate; Chromium oxalate; Ethanedioic acid; Ammonium oxalate; Oxalate, ferric; Oxalate, sodium; Sodium oxalate; Ferric oxalate; Ethandisaeure; Oxalate, iron; Ethanedionate; Ethanedioate; Iron oxalate; Acid, oxalic; oxalic acid; Oxalsaeure; Oxaalzuur; HOOCCOOH; Oxalate; H2Ox; Oxalic acid; Oxalic acid, 99\%



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(0)

代谢反应

45 个相关的代谢反应过程信息。

Reactome(45)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yi Lu, Zeliang Wu, Zhengxi Du, Xiaozhu Lin, Enwei Tian, Fujian Zhang, Zhi Chao. The anti-urolithiasis activity and safety of strangury-relieving herbs: A comparative study based on fruit fly kidney stone model. Journal of ethnopharmacology. 2024 May; 326(?):117968. doi: 10.1016/j.jep.2024.117968. [PMID: 38428655]
  • Yaxi Deng, Hongxia Zhao, Xiaonuo Zhang, Xintong Li, Goujian Chi. The dissipation of organophosphate esters mediated by ryegrass root exudate oxalic acid in soil: Analysis of enzymes activities, microorganism. Chemosphere. 2024 May; 356(?):141896. doi: 10.1016/j.chemosphere.2024.141896. [PMID: 38579949]
  • Arwa Abdulkreem Al-Huqail, Ibtisam Mohammed Alsudays, Suliman Mohammed Suliman Alghanem, Ramzan Anwar, Mujahid Farid, Wajiha Sarfraz, Muhammad Zubair, Zaki Ul Zaman Asam, Mohsin Abbas, Muhammad Rizwan. Treatment of marble industry wastewater by Brassica napus (L.) under oxalic acid amendment: efficacy as fodder and carcinogenic risk assessment. Environmental science and pollution research international. 2024 May; 31(24):35038-35054. doi: 10.1007/s11356-024-33528-y. [PMID: 38720126]
  • Marcin Grąz. Role of oxalic acid in fungal and bacterial metabolism and its biotechnological potential. World journal of microbiology & biotechnology. 2024 Apr; 40(6):178. doi: 10.1007/s11274-024-03973-5. [PMID: 38662173]
  • Cui Xu, Cui Liu, Zuran Li, Yanqun Zu, Jixiu Wang. Response of growth and Pb accumulation characteristics of plants with intercropping Arabis alpina-Zea mays to exogenous oxalic acid. International journal of phytoremediation. 2024; 26(4):472-480. doi: 10.1080/15226514.2023.2248268. [PMID: 37599450]
  • Yunqiang Zhang, Jianyu Liu, Kehua Jiang, Yu Duan, Yiling Zhang, Xue Qiu, Yanhua Fan, Jianguo Zhu, Yongnan Xu. Roots of Zea mays L.: As a Potential Source to Treat Sodium Oxalate-Induced Renal Cell Injury. Journal of agricultural and food chemistry. 2023 Nov; ?(?):. doi: 10.1021/acs.jafc.3c05248. [PMID: 37945529]
  • Lewis J Bartlett, Christian Baker, Selina Bruckner, Keith S Delaplane, Ethan J Hackmeyer, Chama Phankaew, Geoffrey R Williams, Jennifer A Berry. No evidence to support the use of glycerol-oxalic acid mixtures delivered via paper towel for controlling Varroa destructor (Mesostigmata: Varroidae) mites in the Southeast United States. Journal of insect science (Online). 2023 Nov; 23(6):. doi: 10.1093/jisesa/iead097. [PMID: 38055939]
  • Cody Prouty, Hossam F Abou-Shaara, Branden Stanford, James D Ellis, Cameron Jack. Oxalic acid application method and treatment intervals for reduction of Varroa destructor (Mesostigmata: Varroidae) populations in Apis mellifera (Hymenoptera: Apidae) colonies. Journal of insect science (Online). 2023 Nov; 23(6):. doi: 10.1093/jisesa/iead086. [PMID: 38055944]
  • Pan Pan, Huizhan Liu, Ang Liu, Xinchun Zhang, Qingmian Chen, Guihua Wang, Beibei Liu, Qinfen Li, Mei Lei. Rhizosphere environmental factors regulated the cadmium adsorption by vermicompost: Influence of pH and low-molecular-weight organic acids. Ecotoxicology and environmental safety. 2023 Nov; 266(?):115593. doi: 10.1016/j.ecoenv.2023.115593. [PMID: 37856985]
  • Akalesh G Yadav, Prasanta K Mohapatra, Thichur P Valsala, Darshan B Sathe, Raj B Bhatt. Highly efficient separation of Am(III) and Pu(IV) from lean feeds and soil using an extraction chromatographic resin containing a diglycolamide in an ionic liquid. Journal of chromatography. A. 2023 Sep; 1707(?):464299. doi: 10.1016/j.chroma.2023.464299. [PMID: 37597478]
  • Umer Hayat, Shafuq Abbas. Oxalic acid-assisted phytoextraction of heavy metal contaminated wastewater through Lemna minor L. Environmental science and pollution research international. 2023 Sep; ?(?):. doi: 10.1007/s11356-023-29547-w. [PMID: 37695484]
  • Jinwen Yang, Linlin Chen, Jie Qi, Feili Luo, Lin Li, Honghong Wu, Feifei Cao, Jiangjiang Gu. Acid-assisted ultrasonic preparation of nitrogen-doped MXene quantum dots for the efficient fluorescence "off-on-off" detection of Zn(II) in water and oxalic acid in vegetables. Food chemistry. 2023 Jul; 430(?):137007. doi: 10.1016/j.foodchem.2023.137007. [PMID: 37536071]
  • Asif Iqbal, George Nwokocha, Vijay Tiwari, Inderjit K Barphagha, Anne Grove, Jong Hyun Ham, William T Doerrler. A membrane protein of the rice pathogen Burkholderia glumae required for oxalic acid secretion and quorum sensing. Molecular plant pathology. 2023 Jul; ?(?):. doi: 10.1111/mpp.13376. [PMID: 37428013]
  • Yan Liu, Itsuki Nose, Kazuyoshi Terasaka, Tsukasa Fueki, Toshiaki Makino. Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber. Journal of natural medicines. 2023 Jun; ?(?):. doi: 10.1007/s11418-023-01717-7. [PMID: 37311896]
  • Jianhao Yang, Xiaoxiao Liu, Caiyun Fei, Hongjuan Lu, Youhua Ma, Zhongwen Ma, Wenling Ye. Chemical-microbial effects of acetic acid, oxalic acid and citric acid on arsenic transformation and migration in the rhizosphere of paddy soil. Ecotoxicology and environmental safety. 2023 May; 259(?):115046. doi: 10.1016/j.ecoenv.2023.115046. [PMID: 37235901]
  • Muhammad Zia-Ur-Rehman, Manar Fawzi Bani Mfarrej, Muhammad Usman, Muhammad Azhar, Muhammad Rizwan, Hesham F Alharby, Atif A Bamagoos, Rahma Alshamrani, Zahoor Ahmad. Exogenous application of low and high molecular weight organic acids differentially affected the uptake of cadmium in wheat-rice cropping system in alkaline calcareous soil. Environmental pollution (Barking, Essex : 1987). 2023 Apr; 329(?):121682. doi: 10.1016/j.envpol.2023.121682. [PMID: 37094734]
  • Akira Kotani, Hisanobu Ishikawa, Takashi Shii, Minpei Kuroda, Yoshihiro Mimaki, Koichi Machida, Kazuhiro Yamamoto, Hideki Hakamata. Determination of oxalic acid in herbal medicines by semi-micro hydrophilic interaction liquid chromatography coupled with electrochemical detection. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2023 Apr; 39(4):441-446. doi: 10.1007/s44211-022-00245-w. [PMID: 36639558]
  • Hui Yang, Yexuan Liu, Shengnan Wang, Lingling Zhao, He Liu, Jun Liu, Danshi Zhu. Composition, morphology, interfacial rheology and emulsifying ability of soy hull polysaccharides extracted with ammonium oxalate and sodium citrate as extractants. Journal of the science of food and agriculture. 2023 Mar; 103(5):2325-2336. doi: 10.1002/jsfa.12441. [PMID: 36628504]
  • Lin Zhang, Xin Yang, Sensen Li, Lingyi Tang, Tianyi Chen, Tingting Gu, Genqiang Chen, Geoffrey Michael Gadd, Zhen Li. A contrast of Pb(II), Cd(II), and Cu(II) toxicities to Aspergillus niger through biochemical, morphological, and genetic investigations. Journal of hazardous materials. 2023 03; 446(?):130691. doi: 10.1016/j.jhazmat.2022.130691. [PMID: 36608576]
  • Zahra Farhadi, Ali Asghar Sadeghi, Farahnaz Motamedi Sedeh, Mohammad Chamani. The effects of thymol, oxalic acid (Api-Bioxal) and hops extract (Nose-Go) on viability, the Nosema sp. spore load and the expression of vg and sod-1 genes in infected honey bees. Animal biotechnology. 2023 Mar; ?(?):1-10. doi: 10.1080/10495398.2023.2187409. [PMID: 36905146]
  • Kui Kang, Mengyi Zhang, Lei Yue, Weiwen Chen, Yangshuo Dai, Kai Lin, Kai Liu, Jun Lv, Zhanwen Guan, Shi Xiao, Wenqing Zhang. Oxalic Acid Inhibits Feeding Behavior of the Brown Planthopper via Binding to Gustatory Receptor Gr23a. Cells. 2023 02; 12(5):. doi: 10.3390/cells12050771. [PMID: 36899907]
  • Zongming Yang, Pingjuan Zhao, Xuehua Luo, Wentao Peng, Zifan Liu, Guishui Xie, Mengyue Wang, Feng An. An Oxalate Transporter Gene, AtOT, Enhances Aluminum Tolerance in Arabidopsis thaliana by Regulating Oxalate Efflux. International journal of molecular sciences. 2023 Feb; 24(5):. doi: 10.3390/ijms24054516. [PMID: 36901947]
  • Noah James Langenfeld, Bruce Bugbee. An improved digestion and analysis procedure for silicon in plant tissue. PloS one. 2023; 18(9):e0289151. doi: 10.1371/journal.pone.0289151. [PMID: 37682894]
  • Eric Tindanzor, Zhaohui Guo, Tianshuang Li, Rui Xu, Xiyuan Xiao, Chi Peng. Leaching and characterization studies of heavy metals in contaminated soil using sequenced reagents of oxalic acid, citric acid, and a copolymer of maleic and acrylic acid instead of ethylenediaminetetraacetic acid. Environmental science and pollution research international. 2023 Jan; 30(3):6919-6934. doi: 10.1007/s11356-022-22634-4. [PMID: 36018405]
  • Meng Wang, Huimin Yan, Lu Chen, Yu Wang, Lin Li, Han Zhang, Lin Miao. Oxalic acid blocked the binding of spike protein from SARS-CoV-2 Delta (B.1.617.2) and Omicron (B.1.1.529) variants to human angiotensin-converting enzymes 2. PloS one. 2023; 18(5):e0285722. doi: 10.1371/journal.pone.0285722. [PMID: 37200310]
  • Ninghui Cheng, Vincent Paris, Xiaolan Rao, Xiaoqiang Wang, Paul A Nakata. A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism. Plant signaling & behavior. 2022 12; 17(1):2062555. doi: 10.1080/15592324.2022.2062555. [PMID: 35510715]
  • Pengfei Li, Chunlan Liu, Yu Luo, Huineng Shi, Qi Li, Cier PinChu, Xuejiao Li, Jianli Yang, Wei Fan. Oxalate in Plants: Metabolism, Function, Regulation, and Application. Journal of agricultural and food chemistry. 2022 Dec; 70(51):16037-16049. doi: 10.1021/acs.jafc.2c04787. [PMID: 36511327]
  • Yonghui Qiao, Mengwei Zhang, Yuxuan Cao, Qianqian Mi, Shen Liang, Juntao Feng, Yong Wang. Postharvest sclerotinia rot control in carrot by the natural product hinokitiol and the potential mechanisms involved. International journal of food microbiology. 2022 Dec; 383(?):109939. doi: 10.1016/j.ijfoodmicro.2022.109939. [PMID: 36166914]
  • Xiao Liu, Dong-Dong Zhou, Min Chen, Yi-Wen Cao, Lv-Yun Zhuang, Zhi-Heng Lu, Zhong-Hua Yang. Adsorption behavior of azole fungicides on polystyrene and polyethylene microplastics. Chemosphere. 2022 Dec; 308(Pt 2):136280. doi: 10.1016/j.chemosphere.2022.136280. [PMID: 36084829]
  • Yan Yao, Ruiqi Yang, Wenqin Liao, Yuqi Wang, Wei Liu, Xuexia Huang, Xiaolan Wang, Ping Zhang. Is Oxalic Acid Secretion A Detoxification Strategy for Rice Exposed to Tl(I) or Tl(III)?. Bulletin of environmental contamination and toxicology. 2022 Nov; 109(5):920-926. doi: 10.1007/s00128-022-03613-4. [PMID: 36129516]
  • Xiaoqing Wu, Yuping Lyu, He Ren, Fangyuan Zhou, Xinjian Zhang, Xiaoyan Zhao, Guangzhi Zhang, Hetong Yang. Degradation of oxalic acid by Trichoderma afroharzianum and its correlation with cell wall degrading enzymes in antagonizing Botrytis cinerea. Journal of applied microbiology. 2022 Nov; 133(5):2680-2693. doi: 10.1111/jam.15617. [PMID: 35543356]
  • Julia J Vieira, Casey L Johnson, Elizabeth M Varkonyi, Howard S Ginsberg, Kassie L Picard, Matthew K Kiesewetter, Steven R Alm. Using Surrogate Insects in Acid Bioassays for Development of New Controls for Varroa destructor (Arachnida: Varroidae). Journal of economic entomology. 2022 10; 115(5):1417-1422. doi: 10.1093/jee/toac120. [PMID: 35980393]
  • Lingzi Meng, Shang Pan, Limin Zhou, Choochad Santasup, Mu Su, Da Tian, Zhen Li. Evaluating the survival of Aspergillus niger in a highly polluted red soil with addition of Phosphogypsum and bioorganic fertilizer. Environmental science and pollution research international. 2022 Oct; 29(50):76446-76455. doi: 10.1007/s11356-022-21243-5. [PMID: 35670942]
  • Wei Li, Junxing Lu, Chenghuizi Yang, Kate Arildsen, Xin Li, Shitou Xia. An Amidase Contributes to Full Virulence of Sclerotinia sclerotiorum. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911207. [PMID: 36232508]
  • Lv Lv, Kunyan Qiu, Shiji Ge, Zhiqiang Jiao, Chenyang Gao, Haiguang Fu, Rongkui Su, Zhongkai Liu, Yulong Wang, Yangyang Wang. Neutralization and Improvement of Bauxite Residue by Saline-Alkali Tolerant Bacteria. International journal of environmental research and public health. 2022 09; 19(18):. doi: 10.3390/ijerph191811590. [PMID: 36141868]
  • David Santos-Carballal, Nora H de Leeuw. Catalytic formation of oxalic acid on the partially oxidised greigite Fe3S4(001) surface. Physical chemistry chemical physics : PCCP. 2022 Aug; 24(34):20104-20124. doi: 10.1039/d2cp00333c. [PMID: 35983830]
  • Connor J Pedersen, Shin-Yi Lee Marzano. Characterization of Transcriptional Responses to Genomovirus Infection of the White Mold Fungus, Sclerotinia sclerotiorum. Viruses. 2022 08; 14(9):. doi: 10.3390/v14091892. [PMID: 36146699]
  • Yi-Yang Yu, Fang-Jie Si, Ning Wang, Ting Wang, Yu Jin, Ying Zheng, Wei Yang, Yu-Ming Luo, Dong-Dong Niu, Jian-Hua Guo, Chun-Hao Jiang. Bacillus-Secreted Oxalic Acid Induces Tomato Resistance Against Gray Mold Disease Caused by Botrytis cinerea by Activating the JA/ET Pathway. Molecular plant-microbe interactions : MPMI. 2022 Aug; 35(8):659-671. doi: 10.1094/mpmi-11-21-0289-r. [PMID: 36043906]
  • Qi Li, Na Jiang, Xinyue Mei, Yanqun Zu, Zuran Li, Li Qin, Bo Li. Effects of lime and oxalic acid on antioxidant enzymes and active components of Panax notoginseng under cadmium stress. Scientific reports. 2022 07; 12(1):11410. doi: 10.1038/s41598-022-15280-w. [PMID: 35794170]
  • Yashfa Tanveer, Humaira Yasmin, Asia Nosheen, Sajad Ali, Ajaz Ahmad. Ameliorative effects of plant growth promoting bacteria, zinc oxide nanoparticles and oxalic acid on Luffa acutangula grown on arsenic enriched soil. Environmental pollution (Barking, Essex : 1987). 2022 May; 300(?):118889. doi: 10.1016/j.envpol.2022.118889. [PMID: 35085652]
  • Kusum Rana, Junhu Yuan, Hongmei Liao, Surinder S Banga, Rahul Kumar, Wei Qian, Yijuan Ding. Host-induced gene silencing reveals the role of Sclerotinia sclerotiorum oxaloacetate acetylhydrolase gene in fungal oxalic acid accumulation and virulence. Microbiological research. 2022 May; 258(?):126981. doi: 10.1016/j.micres.2022.126981. [PMID: 35183041]
  • L Wang, X Yan, H Hu, J Li, G Jia. Degradation of oxalic acid produced by Botrytis elliptica infection in two ploidy levels of Lilium rosthornii Diels. Plant biology (Stuttgart, Germany). 2022 Apr; 24(3):502-509. doi: 10.1111/plb.13405. [PMID: 35246912]
  • Jiyou Yang, Wanjing Zhang, Yang Wang, Mingfei Li, Feng Peng, Jing Bian. Novel, recyclable Brønsted acidic deep eutectic solvent for mild fractionation of hemicelluloses. Carbohydrate polymers. 2022 Feb; 278(?):118992. doi: 10.1016/j.carbpol.2021.118992. [PMID: 34973795]
  • Seyed Fazel Mirahmadi, Mohammadreza Hassandokht, Reza Fatahi, Mohammad Reza Naghavi, Karamatollah Rezaei. High and low oxalate content in spinach: an investigation of accumulation patterns. Journal of the science of food and agriculture. 2022 Jan; 102(2):836-843. doi: 10.1002/jsfa.11419. [PMID: 34233027]
  • Jennifer A Berry, Lewis J Bartlett, Selina Bruckner, Christian Baker, S Kris Braman, Keith S Delaplane, Geoffrey R Williams. Assessing Repeated Oxalic Acid Vaporization in Honey Bee (Hymenoptera: Apidae) Colonies for Control of the Ectoparasitic Mite Varroa destructor. Journal of insect science (Online). 2022 Jan; 22(1):. doi: 10.1093/jisesa/ieab089. [PMID: 35137130]
  • Natalia Stepanova, Victoria Driianska, Lesya Korol, Lyudmyla Snisar, Larysa Lebed. Plasma oxalic acid and cardiovascular risk in end-stage renal disease patients: a prospective, observational cohort pilot study. The Korean journal of internal medicine. 2022 Jan; 37(1):167-178. doi: 10.3904/kjim.2020.561. [PMID: 34167288]
  • Yuqin Liang, Xiyuan Xiao, Zhaohui Guo, Chi Peng, Peng Zeng, Xiaoyan Wang. Co-application of indole-3-acetic acid/gibberellin and oxalic acid for phytoextraction of cadmium and lead with Sedum alfredii Hance from contaminated soil. Chemosphere. 2021 Dec; 285(?):131420. doi: 10.1016/j.chemosphere.2021.131420. [PMID: 34256202]
  • Nelu Nadejde, Yassir Lemseffer, Laurent Desmurs, Sabine Zaepfel, Flora Kaczorowski, Françoise Poitevin-Later, Marc Guillaumont, Marc Chévrier, Régine Cartier, Denis Monneret. Stability of lactate in venous blood gas and sodium fluoride-potassium oxalate plasma: a 6-year retrospective database analysis. Clinical chemistry and laboratory medicine. 2021 11; 59(12):e438-e441. doi: 10.1515/cclm-2021-0716. [PMID: 34291619]
  • Xinyu Jiang, Mohammad Aqa Mohammadi, Yuan Qin, Zongshen Zhang. Towards Understanding the Involvement of H+-ATPase in Programmed Cell Death of Psammosilene tunicoides after Oxalic Acid Application. Molecules (Basel, Switzerland). 2021 Nov; 26(22):. doi: 10.3390/molecules26226957. [PMID: 34834048]
  • Yun Ji, Shuting Fang, Ying Yang, Zhenlong Wu. Inactivation of the Wnt/β-catenin signaling contributes to the epithelial barrier dysfunction induced by sodium oxalate in canine renal epithelial cells. Journal of animal science. 2021 Oct; 99(10):. doi: 10.1093/jas/skab268. [PMID: 34549281]
  • Qing-Lin Ye, Da-Ming Wang, Xin Wang, Zhi-Qiang Zhang, Qi-Xing Tian, Shi-Yao Feng, Zhi-Hui Zhang, De-Xin Yu, De-Mao Ding, Dong-Dong Xie. Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury. Chemico-biological interactions. 2021 Sep; 347(?):109605. doi: 10.1016/j.cbi.2021.109605. [PMID: 34333021]
  • Qionghou Li, Xin Qiao, Luting Jia, Yuxin Zhang, Shaoling Zhang. Transcriptome and Resequencing Analyses Provide Insight into Differences in Organic Acid Accumulation in Two Pear Varieties. International journal of molecular sciences. 2021 Sep; 22(17):. doi: 10.3390/ijms22179622. [PMID: 34502530]
  • Yong-Mei Xing, Bing Li, Xu Zeng, Li-Si Zhou, Tae-Soo Lee, Min-Woong Lee, Xiao-Mei Chen, Shun-Xing Guo. Use of transcriptomic profiling to identify candidate genes involved in Polyporus umbellatus sclerotial formation affected by oxalic acid. Scientific reports. 2021 08; 11(1):17326. doi: 10.1038/s41598-021-96740-7. [PMID: 34462479]
  • Thayane Crestani, Renato O Crajoinas, Leonardo Jensen, Leno L Dima, Perrine Burdeyron, Thierry Hauet, Sebastien Giraud, Clara Steichen. A Sodium Oxalate-Rich Diet Induces Chronic Kidney Disease and Cardiac Dysfunction in Rats. International journal of molecular sciences. 2021 Aug; 22(17):. doi: 10.3390/ijms22179244. [PMID: 34502149]
  • Paleerath Peerapen, Visith Thongboonkerd. Calcium oxalate monohydrate crystal disrupts tight junction via F-actin reorganization. Chemico-biological interactions. 2021 Aug; 345(?):109557. doi: 10.1016/j.cbi.2021.109557. [PMID: 34147488]
  • Lama Nazzal, Fritz Francois, Nora Henderson, Menghan Liu, Huilin Li, Hyunwook Koh, Chan Wang, Zhan Gao, Guillermo Perez Perez, John R Asplin, David S Goldfarb, Martin J Blaser. Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion. Scientific reports. 2021 08; 11(1):16428. doi: 10.1038/s41598-021-95992-7. [PMID: 34385560]
  • Bilal Rasool, Mahmood Ur-Rahman, Pia Muhammad Adnan Ramzani, Muhammad Zubair, Muhammad Asaf Khan, Karolina Lewińska, Veysel Turan, Anna Karczewska, Shahbaz Ali Khan, Muniba Farhad, Hafiz Muhammad Tauqeer, Muhammad Iqbal. Impacts of oxalic acid-activated phosphate rock and root-induced changes on Pb bioavailability in the rhizosphere and its distribution in mung bean plant. Environmental pollution (Barking, Essex : 1987). 2021 Jul; 280(?):116903. doi: 10.1016/j.envpol.2021.116903. [PMID: 33780846]
  • Fathima Shihana, Wilson K M Wong, Mugdha V Joglekar, Fahim Mohamed, Indika B Gawarammana, Geoffrey K Isbister, Anandwardhan A Hardikar, Devanshi Seth, Nicholas A Buckley. Urinary microRNAs as non-invasive biomarkers for toxic acute kidney injury in humans. Scientific reports. 2021 04; 11(1):9165. doi: 10.1038/s41598-021-87918-0. [PMID: 33911095]
  • Pan Wang, Hongxian Zhang, Jiansuo Zhou, Shangjia Jin, Chong Liu, Boxin Yang, Liyan Cui. Study of risk factor of urinary calculi according to the association between stone composition with urine component. Scientific reports. 2021 04; 11(1):8723. doi: 10.1038/s41598-021-87733-7. [PMID: 33888737]
  • Aleksandra Skalska, Elzbieta Wolny, Manfred Beckmann, John H Doonan, Robert Hasterok, Luis A J Mur. Allotetraploidization in Brachypodium May Have Led to the Dominance of One Parent's Metabolome in Germinating Seeds. Cells. 2021 04; 10(4):. doi: 10.3390/cells10040828. [PMID: 33917018]
  • Nalaka Herath, Gathika Kodithuwakku, Tharaka Dissanayake, Neelakanthi Rathnathunga, Kosala Weerakoon. Acute Kidney Injury Following Star Fruit Ingestion: A Case Series. Wilderness & environmental medicine. 2021 Mar; 32(1):98-101. doi: 10.1016/j.wem.2020.11.003. [PMID: 33518496]
  • Éva Kolics, András Specziár, János Taller, Kinga Klára Mátyás, Balázs Kolics. Lithium chloride outperformed oxalic acid sublimation in a preliminary experiment for Varroa mite control in pre-wintering honey bee colonies. Acta veterinaria Hungarica. 2021 01; 68(4):370-373. doi: 10.1556/004.2020.00060. [PMID: 33459613]
  • Qodratollah Sabahi, Nuria Morfin, Berna Emsen, Hanan A Gashout, Paul G Kelly, Stephanie Otto, A Rod Merrill, Ernesto Guzman-Novoa. Evaluation of Dry and Wet Formulations of Oxalic Acid, Thymol, and Oregano Oil for Varroa Mite (Acari: Varroidae) Control in Honey Bee (Hymenoptera: Apidae) Colonies. Journal of economic entomology. 2020 12; 113(6):2588-2594. doi: 10.1093/jee/toaa218. [PMID: 33001171]
  • Osama Atallah, Sherene Yassin. Aspergillus spp. eliminate Sclerotinia sclerotiorum by imbalancing the ambient oxalic acid concentration and parasitizing its sclerotia. Environmental microbiology. 2020 12; 22(12):5265-5279. doi: 10.1111/1462-2920.15213. [PMID: 32844537]
  • Thilini Madushanka Wijerathna, Fahim Mohamed, Indika Bandara Gawarammana, Klintean Wunnapuk, Dhammika Menike Dissanayake, Fathima Shihana, Nicholas Allan Buckley. Cellular injury leading to oxidative stress in acute poisoning with potassium permanganate/oxalic acid, paraquat, and glyphosate surfactant herbicide. Environmental toxicology and pharmacology. 2020 Nov; 80(?):103510. doi: 10.1016/j.etap.2020.103510. [PMID: 33031936]
  • Fathima Shihana, Fahim Mohamed, Mugdha V Joglekar, Anandwardhan A Hardikar, Devanshi Seth, Nicholas A Buckley. Urinary versus serum microRNAs in human oxalic acid poisoning: Contrasting signals and performance. Toxicology letters. 2020 Nov; 334(?):21-26. doi: 10.1016/j.toxlet.2020.09.003. [PMID: 32910981]
  • Osama M Ahmed, Hossam Ebaid, El-Shaymaa El-Nahass, Mahmoud Ragab, Ibrahim M Alhazza. Nephroprotective Effect of Pleurotus ostreatus and Agaricus bisporus Extracts and Carvedilol on Ethylene Glycol-Induced Urolithiasis: Roles of NF-κB, p53, Bcl-2, Bax and Bak. Biomolecules. 2020 09; 10(9):. doi: 10.3390/biom10091317. [PMID: 32937925]
  • Fumiyoshi Kojima, Jatin S Gandhi, Ibu Matsuzaki, Akinori Iba, Scott Collier, Takanori Yoshikawa, Yuichi Kinoshita, Kenji Warigaya, Masakazu Fujimoto, Naoto Kuroda, Eiichi Morii, Isao Hara, Shin-Ichi Murata, Mahul B Amin. Comprehensive Clinicopathologic Analyses of Acquired Cystic Disease-associated Renal Cell Carcinoma With Focus on Adverse Prognostic Factors and Metastatic Lesions. The American journal of surgical pathology. 2020 08; 44(8):1031-1039. doi: 10.1097/pas.0000000000001482. [PMID: 32271189]
  • Anna Kletzmayr, Mattias E Ivarsson, Jean-Christophe Leroux. Investigational Therapies for Primary Hyperoxaluria. Bioconjugate chemistry. 2020 07; 31(7):1696-1707. doi: 10.1021/acs.bioconjchem.0c00268. [PMID: 32539351]
  • Emmanuel Letavernier, Michel Daudon. Stiripentol identifies a therapeutic target to reduce oxaluria. Current opinion in nephrology and hypertension. 2020 07; 29(4):394-399. doi: 10.1097/mnh.0000000000000621. [PMID: 32452916]
  • Amany A Sayed, Sohair R Fahmy, Amel M Soliman, Dina M Mohamed. Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats. Pakistan journal of pharmaceutical sciences. 2020 Jul; 33(4):1679-1688. doi: NULL. [PMID: 33583802]
  • Yuanyuan Wang, Yonglin Wang. Oxalic Acid Metabolism Contributes to Full Virulence and Pycnidial Development in the Poplar Canker Fungus Cytospora chrysosperma. Phytopathology. 2020 Jul; 110(7):1319-1325. doi: 10.1094/phyto-10-19-0381-r. [PMID: 32154765]
  • Dawn S Milliner, Tracy L McGregor, Aliza Thompson, Bastian Dehmel, John Knight, Ralf Rosskamp, Melanie Blank, Sixun Yang, Sonia Fargue, Gill Rumsby, Jaap Groothoff, Meaghan Allain, Melissa West, Kim Hollander, W Todd Lowther, John C Lieske. End Points for Clinical Trials in Primary Hyperoxaluria. Clinical journal of the American Society of Nephrology : CJASN. 2020 07; 15(7):1056-1065. doi: 10.2215/cjn.13821119. [PMID: 32165440]
  • Ishaat M Khan, Sonam Shakya, Roushan Akhtar, Kehkashan Alam, Maidul Islam, Nisat Alam. Exploring interaction dynamics of designed organic cocrystal charge transfer complex of 2-hydroxypyridine and oxalic acid with human serum albumin: Single crystal, spectrophotometric, theoretical and antimicrobial studies. Bioorganic chemistry. 2020 07; 100(?):103872. doi: 10.1016/j.bioorg.2020.103872. [PMID: 32348934]
  • Sajid Ali, Ahmad Sattar Khan, Muhammad Akbar Anjum, Aamir Nawaz, Safina Naz, Shaghef Ejaz, Sajjad Hussain. Effect of postharvest oxalic acid application on enzymatic browning and quality of lotus (Nelumbo nuciferaGaertn.) root slices. Food chemistry. 2020 May; 312(?):126051. doi: 10.1016/j.foodchem.2019.126051. [PMID: 31891888]
  • Fathima Shihana, Mugdha V Joglekar, Jacques Raubenheimer, Anandwardhan A Hardikar, Nicholas A Buckley, Devanshi Seth. Circulating human microRNA biomarkers of oxalic acid-induced acute kidney injury. Archives of toxicology. 2020 05; 94(5):1725-1737. doi: 10.1007/s00204-020-02679-5. [PMID: 32086547]
  • Youfa Luo, Xingyu Wu, Hang Sun, Yonggui Wu. Root-induced changes in aggregation characteristics and potentially toxic elements (PTEs) speciation in a revegetated artificial zinc smelting waste slag site. Chemosphere. 2020 Mar; 243(?):125414. doi: 10.1016/j.chemosphere.2019.125414. [PMID: 31783184]
  • Xiaoxia Peng, Guang Yang, Yun Shi, Yifa Zhou, Mengshan Zhang, Shanshan Li. Box-Behnken design based statistical modeling for the extraction and physicochemical properties of pectin from sunflower heads and the comparison with commercial low-methoxyl pectin. Scientific reports. 2020 02; 10(1):3595. doi: 10.1038/s41598-020-60339-1. [PMID: 32108167]
  • Xin Wang, Yanan Zhang, Shuai Han, Hongshen Chen, Chen Chen, Lingling Ji, Bihu Gao. Overexpression of miR‑30c‑5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5. International journal of molecular medicine. 2020 Feb; 45(2):375-384. doi: 10.3892/ijmm.2019.4440. [PMID: 31894301]
  • Isato Yoshioka, Keiichi Kobayashi, Kohtaro Kirimura. Overexpression of the gene encoding alternative oxidase for enhanced glucose consumption in oxalic acid producing Aspergillus niger expressing oxaloacetate hydrolase gene. Journal of bioscience and bioengineering. 2020 Feb; 129(2):172-176. doi: 10.1016/j.jbiosc.2019.08.014. [PMID: 31611058]
  • Lizhang Zeng, Xiangbo Yang, Jun Zhou. The xanthophyll cycle as an early pathogenic target to deregulate guard cells during Sclerotinia sclerotiorum infection. Plant signaling & behavior. 2020; 15(1):1691704. doi: 10.1080/15592324.2019.1691704. [PMID: 31724459]
  • Li Chen, Dan Wang, Chan Long, Zheng-Xu Cui. Effect of biodegradable chelators on induced phytoextraction of uranium- and cadmium- contaminated soil by Zebrina pendula Schnizl. Scientific reports. 2019 12; 9(1):19817. doi: 10.1038/s41598-019-56262-9. [PMID: 31875012]
  • Xue-Ping Huang, Jian Luo, Bei-Xing Li, Yu-Fei Song, Wei Mu, Feng Liu. Bioactivity, physiological characteristics and efficacy of the SDHI fungicide pydiflumetofen against Sclerotinia sclerotiorum. Pesticide biochemistry and physiology. 2019 Oct; 160(?):70-78. doi: 10.1016/j.pestbp.2019.06.017. [PMID: 31519259]
  • Xiaohui Wang, Huiling Li, Qixuan Lin, Rui Li, Weiying Li, Xiaohui Wang, Feng Peng, Junli Ren. Efficient catalytic conversion of dilute-oxalic acid pretreated bagasse hydrolysate to furfural using recyclable ironic phosphates catalysts. Bioresource technology. 2019 Oct; 290(?):121764. doi: 10.1016/j.biortech.2019.121764. [PMID: 31310865]
  • Qun Jiang, Yifan Wang, Yan Gao, Ying Zhang. Fabrication and characterization of a hierarchical porous carbon from corn straw-derived hydrochar for atrazine removal: efficiency and interface mechanisms. Environmental science and pollution research international. 2019 Oct; 26(29):30268-30278. doi: 10.1007/s11356-019-06174-y. [PMID: 31428966]
  • María Marina, Fernando M Romero, Natalia M Villarreal, Andrés J Medina, Andrés Gárriz, Franco R Rossi, Gustavo A Martinez, Fernando L Pieckenstain. Mechanisms of plant protection against two oxalate-producing fungal pathogens by oxalotrophic strains of Stenotrophomonas spp. Plant molecular biology. 2019 Aug; 100(6):659-674. doi: 10.1007/s11103-019-00888-w. [PMID: 31187392]
  • Sajeli Begum Ahil, Kirti Hira, Ameer Basha Shaik, Pragya Paramita Pal, Onkar Prakash Kulkarni, Hiroshi Araya, Yoshinori Fujimoto. l-Proline-based-cyclic dipeptides from Pseudomonas sp. (ABS-36) inhibit pro-inflammatory cytokines and alleviate crystal-induced renal injury in mice. International immunopharmacology. 2019 Aug; 73(?):395-404. doi: 10.1016/j.intimp.2019.05.044. [PMID: 31151077]
  • Arivarasu N Anbazhagan, Shubha Priyamvada, Alip Borthakur, Seema Saksena, Ravinder K Gill, Waddah A Alrefai, Pradeep K Dudeja. miR-125a-5p: a novel regulator of SLC26A6 expression in intestinal epithelial cells. American journal of physiology. Cell physiology. 2019 08; 317(2):C200-C208. doi: 10.1152/ajpcell.00068.2019. [PMID: 31042422]
  • Lucia Sabová, Anna Sobeková, Martin Staroň, Rastislav Sabo, Jaroslav Legáth, Dana Staroňová, Ľuboslava Lohajová, Peter Javorský. Toxicity of oxalic acid and impact on some antioxidant enzymes on in vitro-reared honeybee larvae. Environmental science and pollution research international. 2019 Jul; 26(19):19763-19769. doi: 10.1007/s11356-019-05247-2. [PMID: 31089998]
  • Taher Alizadeh, Sahar Nayeri. Graphite/Ag/AgCl nanocomposite as a new and highly efficient electrocatalyst for selective electroxidation of oxalic acid and its assay in real samples. Materials science & engineering. C, Materials for biological applications. 2019 Jul; 100(?):826-836. doi: 10.1016/j.msec.2019.03.052. [PMID: 30948120]
  • Jian-Li Yang, Wei Fan, Shao-Jian Zheng. Mechanisms and regulation of aluminum-induced secretion of organic acid anions from plant roots. Journal of Zhejiang University. Science. B. 2019 Jun; 20(6):513-527. doi: 10.1631/jzus.b1900188. [PMID: 31090277]
  • Wei Jia, ChengXiao Hu, JiaYang Xu, JiaJia Ming, YuanYuan Zhao, MiaoMiao Cai, XueCheng Sun, XinWei Liu, XiaoHu Zhao. Dissolved organic matter derived from rape straw pretreated with selenium in soil improves the inhibition of Sclerotinia sclerotiorum growth. Journal of hazardous materials. 2019 05; 369(?):601-610. doi: 10.1016/j.jhazmat.2019.02.055. [PMID: 30825806]
  • Fanxu Meng, Yuan Gao, Qingyuan Feng. Discovery and mechanism study of a novel chromium-accumulating plant, Lonicera japonica Thunb. Environmental science and pollution research international. 2019 May; 26(14):13812-13817. doi: 10.1007/s11356-018-3182-9. [PMID: 30220064]
  • Spyridon A Petropoulos, Ângela Fernandes, Nikolaos Tzortzakis, Marina Sokovic, Ana Ciric, Lillian Barros, Isabel C F R Ferreira. Bioactive compounds content and antimicrobial activities of wild edible Asteraceae species of the Mediterranean flora under commercial cultivation conditions. Food research international (Ottawa, Ont.). 2019 05; 119(?):859-868. doi: 10.1016/j.foodres.2018.10.069. [PMID: 30884726]
  • Murray B McBride, Sabrina E Kelch, Michael P Schmidt, Sonam Sherpa, Carmen Enid Martinez, Ludmilla Aristilde. Oxalate-enhanced solubility of lead (Pb) in the presence of phosphate: pH control on mineral precipitation. Environmental science. Processes & impacts. 2019 Apr; 21(4):738-747. doi: 10.1039/c8em00553b. [PMID: 30895974]
  • Ana Rita Silva, Ângela Fernandes, Pablo A García, Lillian Barros, Isabel C F R Ferreira. Cytinus hypocistis (L.) L. subsp. macranthus Wettst.: Nutritional Characterization. Molecules (Basel, Switzerland). 2019 Mar; 24(6):. doi: 10.3390/molecules24061111. [PMID: 30897825]
  • Chaitanya Sarangapani, Dana Ziuzina, Patrice Behan, Daniela Boehm, Brendan F Gilmore, P J Cullen, Paula Bourke. Degradation kinetics of cold plasma-treated antibiotics and their antimicrobial activity. Scientific reports. 2019 03; 9(1):3955. doi: 10.1038/s41598-019-40352-9. [PMID: 30850645]
  • Jorge Armesto, Lucía Gómez-Limia, Javier Carballo, Sidonia Martínez. Effects of different cooking methods on the antioxidant capacity and flavonoid, organic acid and mineral contents of Galega Kale (Brassica oleracea var. acephala cv. Galega). International journal of food sciences and nutrition. 2019 Mar; 70(2):136-149. doi: 10.1080/09637486.2018.1482530. [PMID: 30037287]
  • Nathaniel M Westrick, Ashish Ranjan, Sachin Jain, Craig R Grau, Damon L Smith, Mehdi Kabbage. Gene regulation of Sclerotinia sclerotiorum during infection of Glycine max: on the road to pathogenesis. BMC genomics. 2019 Feb; 20(1):157. doi: 10.1186/s12864-019-5517-4. [PMID: 30808300]