P-Hydroxyphenylethanolamine (BioDeep_00000004096)

 

Secondary id: BioDeep_00001868514

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


alpha-(Aminoethyl)-4-hydroxybenzenemethanol

化学式: C8H11NO2 (153.079)
中文名称: 章胺, 章鱼胺, 对羟基苯乙醇胺, 奥克巴胺
谱图信息: 最多检出来源 Homo sapiens(blood) 18.21%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

P-Hydroxyphenylethanolamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/p-hydroxyphenylethanolamine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000004096). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CC=C1C(CN)O)O
InChI: InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2

描述信息

Alkaloid from leaves of tabasco pepper (Capsicum frutescens), nutgrass (Cyperus rotundus) and leaves or fruit of Citrus subspecies Occurs in many animal tissues; found in high concs. in octopus
p-Octopamine is an amine in traces quantities in plasma and cerebrospinal fluid in humans with septic encephalopathy (PMID 15932098).
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist

同义名列表

29 个代谢物同义名

alpha-(Aminoethyl)-4-hydroxybenzenemethanol; 4-[(1R)-2-amino-1-hydroxyethyl]phenol; 2-amino-1-(4-Hydroxyphenyl)ethanol; 1-(P-Hydroxyphenyl)-2-aminoethanol; 1-(4-Hydroxyphenyl)-2-aminoethanol; 4-(2R-AMINO-1-hydroxyethyl)phenol; 4-[2-amino-1-Hydroxyethyl]phenol; p-Hydroxyphenylethanolamine; 4-Hydroxyphenethanolamine; Racemic octopamine; (RS)-Octopamine; Para-octopamine; (R)-Octopamine; DL-Octopamine; Norsynephrine; 4-Octopamine; p-Octopamine; Norsympathol; Norsympatol; octopamine; Norphen; Norton; Analet; Norden; ND 50; Octopamine (p-Hydroxyphenylethanolamine); p-Octopamine; Octopamine; US10112926, Example 104.14



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AANAT, AOC3, CHAT, GPR143, GTPBP4, ITPR3
Peripheral membrane protein 1 ACHE
Endosome membrane 1 CLCN5
Endoplasmic reticulum membrane 3 DRD1, ITPR3, PNMT
Mitochondrion membrane 1 PNMT
Nucleus 5 ACHE, CHAT, DRD1, GTPBP4, PLCZ1
cytosol 8 AANAT, CHAT, CLCN5, GTPBP4, PAH, PLCZ1, PNMT, PRKCQ
mitochondrial membrane 1 PNMT
nucleoplasm 3 GTPBP4, ITPR3, PLCZ1
Cell membrane 5 ACHE, AOC3, CLCN5, DRD1, GPRC5A
Multi-pass membrane protein 7 CLCN5, DRD1, GPR143, GPRC5A, ITPR3, KCNA3, PNMT
Golgi apparatus membrane 1 CLCN5
Synapse 3 ACHE, CHAT, NPS
cell surface 2 ACHE, AOC3
glutamatergic synapse 2 DRD1, KCNA3
Golgi apparatus 5 ACHE, AOC3, ATRN, CLCN5, GPR143
Golgi membrane 2 CLCN5, INS
lysosomal membrane 2 CLCN5, GPR143
neuromuscular junction 1 ACHE
neuronal cell body 1 ITPR3
presynaptic membrane 2 DRD1, KCNA3
synaptic vesicle 1 CLCN5
plasma membrane 10 ACHE, AOC3, ATRN, CLCN5, DRD1, GPR143, GPRC5A, ITPR3, KCNA3, PRKCQ
Membrane 7 ACHE, AOC3, CLCN5, GPR143, GTPBP4, ITPR3, KCNA3
apical plasma membrane 1 GPR143
axon 2 CCK, KCNA3
brush border 1 ITPR3
extracellular exosome 3 ATRN, GPRC5A, LYZ
Lysosome membrane 1 GPR143
endoplasmic reticulum 3 AOC3, ITPR3, PNMT
extracellular space 5 ACHE, ATRN, CCK, INS, LYZ
perinuclear region of cytoplasm 5 AANAT, ACHE, GTPBP4, KCNA3, PLCZ1
mitochondrion 1 PNMT
intracellular membrane-bounded organelle 2 GPRC5A, PNMT
pronucleus 1 PLCZ1
Single-pass type I membrane protein 1 ATRN
Secreted 3 ACHE, CCK, INS
extracellular region 5 ACHE, CCK, INS, LYZ, NPS
[Isoform 2]: Secreted 1 ATRN
Extracellular side 1 ACHE
centriolar satellite 1 PRKCQ
ciliary membrane 1 DRD1
nuclear membrane 1 GTPBP4
dendritic spine 1 DRD1
nucleolus 4 GPRC5A, GTPBP4, ITPR3, PLCZ1
Melanosome membrane 1 GPR143
Early endosome 2 AOC3, CLCN5
apical part of cell 2 CLCN5, ITPR3
Single-pass type II membrane protein 1 AOC3
vesicle 1 GPRC5A
postsynaptic membrane 2 DRD1, KCNA3
Apical cell membrane 1 GPR143
Cytoplasm, perinuclear region 1 PLCZ1
Membrane raft 1 KCNA3
GABA-ergic synapse 1 DRD1
basement membrane 1 ACHE
sarcoplasmic reticulum 1 ITPR3
Cell projection, dendritic spine 1 DRD1
nuclear outer membrane 1 ITPR3
receptor complex 2 GPRC5A, ITPR3
neuron projection 1 CHAT
cilium 1 DRD1
Nucleus, nucleolus 1 GTPBP4
non-motile cilium 1 DRD1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 KCNA3
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 INS
microvillus 1 AOC3
[Isoform 1]: Endoplasmic reticulum membrane 1 PNMT
Cytoplasmic vesicle membrane 1 GPRC5A
Cell projection, dendrite 1 DRD1
Melanosome 1 GPR143
side of membrane 1 ACHE
voltage-gated potassium channel complex 1 KCNA3
secretory granule lumen 1 INS
secretory granule membrane 1 ITPR3
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
transport vesicle 1 INS
azurophil granule lumen 1 LYZ
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
calyx of Held 1 KCNA3
platelet dense tubular network membrane 1 ITPR3
synaptic cleft 1 ACHE
[Isoform 1]: Cell membrane 2 ATRN, KCNA3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
[Isoform 2]: Endoplasmic reticulum membrane 1 PNMT
Cell projection, cilium membrane 1 DRD1
transport vesicle membrane 1 ITPR3
sperm head 1 PLCZ1
G protein-coupled receptor complex 1 DRD1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3
[Isoform H]: Cell membrane 1 ACHE


文献列表

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