meclofenoxate (BioDeep_00000408903)

Main id: BioDeep_00000006683

 


代谢物信息卡片


2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

化学式: C12H16ClNO3 (257.0818656)
中文名称: 氯酯醒
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)CCOC(=O)COc(c1)ccc(Cl)c1
InChI: InChI=1S/C12H16ClNO3/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11/h3-6H,7-9H2,1-2H3

描述信息

N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
D002491 - Central Nervous System Agents > D018697 - Nootropic Agents
D020011 - Protective Agents

同义名列表

2 个代谢物同义名

2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate; meclofenoxate



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
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  • Rasha M El-Nashar, Nour T Abdel Ghani, Sherif M Hassan. Construction and performance characteristics of new ion selective electrodes based on carbon nanotubes for determination of meclofenoxate hydrochloride. Analytica chimica acta. 2012 Jun; 730(?):99-111. doi: 10.1016/j.aca.2011.10.069. [PMID: 22632051]
  • Ze-qiang Qu, Yan Zhou, Yuan-shan Zeng, Yu-kun Lin, Yan Li, Zhi-qiang Zhong, Wood Yee Chan. Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat. PloS one. 2012; 7(1):e29641. doi: 10.1371/journal.pone.0029641. [PMID: 22235318]
  • Jade W Wei, Yining Huang, Ji-Guang Wang, Ming Liu, Lawrence K S Wong, Qifang Huang, Li'e Wu, Emma L Heeley, Hisatomi Arima, Craig S Anderson. Current management of intracerebral haemorrhage in China: a national, multi-centre, hospital register study. BMC neurology. 2011 Jan; 11(?):16. doi: 10.1186/1471-2377-11-16. [PMID: 21276264]
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  • Bin Ni, Junren Zhang, Jianjun Zou, Wei Zhao, JianHua Li. A simple and sensitive HPLC method for quantification of the metabolin of meclofenoxate in human plasma. Journal of chromatographic science. 2010 May; 48(5):353-7. doi: 10.1093/chromsci/48.5.353. [PMID: 20515527]
  • Ranjeet Verma, Bimla Nehru. Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease. Neurochemistry international. 2009 Nov; 55(6):369-75. doi: 10.1016/j.neuint.2009.04.001. [PMID: 19375462]
  • Jian-Jun Zou, Hong-Jian Ji, Ding-Wei Wu, Jing Yao, Qin Hu, Da-Wei Xiao, Guang-Ji Wang. Bioequivalence and pharmacokinetic comparison of a single 200-mg dose of meclofenoxate hydrochloride capsule and tablet formulations in healthy Chinese adult male volunteers: a randomized sequence, open-label, two-period crossover study. Clinical therapeutics. 2008 Sep; 30(9):1651-7. doi: 10.1016/j.clinthera.2008.09.013. [PMID: 18840370]
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  • Mohammad Galal El-Bardicy, Hayam Mahmoud Lotfy, Mohammad Abdalla El-Sayed, Mohammad Fayez El-Tarras. Stability-indicating electrochemical methods for the determination of meclophenoxate hydrochloride and pyritinol dihydrochloride using ion-selective membrane electrodes. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2007 Jan; 127(1):201-8. doi: 10.1248/yakushi.127.201. [PMID: 17202801]
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