1,10-phenanthroline (BioDeep_00000400187)

Main id: BioDeep_00000003011

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


1,10-Phenanthroline monohydrate

化学式: C12H8N2 (180.0687448)
中文名称: 1,10-菲罗啉(无水)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1
InChI: InChI=1/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H

描述信息

D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors

同义名列表

2 个代谢物同义名

1,10-phenanthroline; 1,10-Phenanthroline monohydrate



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(59)

PlantCyc(5)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yu Wang, Zhouhui Wu, Zhiwen Wang, Heng Du, Shuang Xiao, Lin Lu, Zhen Wang. Analyses of the Antibiofilm Activity of o-Phenanthroline Monohydrate against Enterococcus faecalis and Staphylococcus aureus and the Mechanisms Underlying These Effects. ACS infectious diseases. 2024 Feb; 10(2):638-649. doi: 10.1021/acsinfecdis.3c00516. [PMID: 38258383]
  • Anđela Bačinić, Sanja Frka, Marina Mlakar. A study of cobalt (II) complexes involved in marine biogeochemical processes: Co(II)-1,10-Phenanthroline and Co(II)-1,10-Phenanthroline-L-α-Phosphatidylcholine. Bioelectrochemistry (Amsterdam, Netherlands). 2022 Apr; 144(?):108009. doi: 10.1016/j.bioelechem.2021.108009. [PMID: 34902665]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Geraldine Backman-Blanco, Hugo Valdés, María Teresa Ramírez-Apan, Patricia Cano-Sanchez, Simón Hernandez-Ortega, Adrian L Orjuela, Jorge Alí-Torres, Areli Flores-Gaspar, Reyna Reyes-Martínez, David Morales-Morales. Synthesis of Pt(II) complexes of the type [Pt(1,10-phenanthroline)(SArFn)2] (SArFn = SC6H3-3,4-F2; SC6F4-4-H; SC6F5). Preliminary evaluation of their in vitro anticancer activity. Journal of inorganic biochemistry. 2020 10; 211(?):111206. doi: 10.1016/j.jinorgbio.2020.111206. [PMID: 32801098]
  • Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta. The first copper(ii) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties. Metallomics : integrated biometal science. 2020 06; 12(6):891-901. doi: 10.1039/d0mt00006j. [PMID: 32337526]
  • Masoomeh Shaghaghi, Samaneh Rashtbari, Asma Abdollahi, Gholamreza Dehghan, Abolghasem Jouyban. A Sensitive, Simple and Direct Determination of Pantoprazole Based on a 'Turn off-on' Fluorescence Nanosensor by Using Terbium-1,10-phenanthroline-silver Nanoparticles. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2020; 36(11):1345-1352. doi: 10.2116/analsci.20p142. [PMID: 33177314]
  • Aarti Upadhyay, Srishti Gautam, Vanitha Ramu, Paturu Kondaiah, Akhil R Chakravarty. Photocytotoxic cancer cell-targeting platinum(ii) complexes of glucose-appended curcumin and biotinylated 1,10-phenanthroline. Dalton transactions (Cambridge, England : 2003). 2019 Dec; 48(47):17556-17565. doi: 10.1039/c9dt03490k. [PMID: 31748772]
  • Shohreh Jahani, Meissam Noroozifar, Mozhgan Khorasani-Motlagh, Masoud Torkzadeh-Mahani, Mahboubeh Adeli-Sardou. In vitro cytotoxicity studies of parent and nanoencapsulated Holmium-2,9-dimethyl-1,10-phenanthroline complex toward fish-salmon DNA-binding properties and antibacterial activity. Journal of biomolecular structure & dynamics. 2019 10; 37(17):4437-4449. doi: 10.1080/07391102.2018.1557077. [PMID: 30526398]
  • Zohreh Moradi, Mozhgan Khorasani-Motlagh, Ali Reza Rezvani, Meissam Noroozifar. Electronic and fluorescent studies on the interaction of DNA and BSA with a new ternary praseodymium complex containing 2,9-dimethyl 1,10-phenanthroline and antibacterial activities testing. Journal of biomolecular structure & dynamics. 2019 Jun; 37(9):2283-2295. doi: 10.1080/07391102.2018.1479657. [PMID: 30035684]
  • Afzal Hussain, Mohamed Fahad AlAjmi, Md Tabish Rehman, Samira Amir, Fohad Mabood Husain, Ali Alsalme, Maqsood Ahmad Siddiqui, Abdulaziz A AlKhedhairy, Rais Ahmad Khan. Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies. Scientific reports. 2019 03; 9(1):5237. doi: 10.1038/s41598-019-41063-x. [PMID: 30918270]
  • Neville S Ng, Ming J Wu, Janice R Aldrich-Wright. The cytotoxicity of some phenanthroline-based antimicrobial copper(II) and ruthenium(II) complexes. Journal of inorganic biochemistry. 2018 03; 180(?):61-68. doi: 10.1016/j.jinorgbio.2017.11.022. [PMID: 29247868]
  • Eduardo Luiz Rossini, Maria Izabel Milani, Emanuel Carrilho, Leonardo Pezza, Helena Redigolo Pezza. Simultaneous determination of renal function biomarkers in urine using a validated paper-based microfluidic analytical device. Analytica chimica acta. 2018 Jan; 997(?):16-23. doi: 10.1016/j.aca.2017.10.018. [PMID: 29149990]
  • Juan Zhen, Maarten E A Reith. Functional properties of dopamine transporter oligomers after copper linking. Journal of neurochemistry. 2018 01; 144(2):162-171. doi: 10.1111/jnc.14259. [PMID: 29168892]
  • Surbhi Jain, Tanveer A Khan, Yogesh P Patil, Darshana Pagariya, Nand Kishore, Suman Tapryal, Anil D Naik, Sunil G Naik. Bio-affinity of copper(II) complexes with nitrogen and oxygen donor ligands: Synthesis, structural studies and in vitro DNA and HSA interaction of copper(II) complexes. Journal of photochemistry and photobiology. B, Biology. 2017 Sep; 174(?):35-43. doi: 10.1016/j.jphotobiol.2017.06.035. [PMID: 28753522]
  • Qingming Wang, Han Mao, Wenling Wang, Huimin Zhu, Lihui Dai, Yanli Chen, Xinhui Tang. Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper(II)/zinc(II) complexes. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2017 08; 30(4):575-587. doi: 10.1007/s10534-017-0028-8. [PMID: 28616784]
  • Benjamin W J Harper, Aviva Friedman-Ezra, Roman Sirota, Emanuele Petruzzella, Janice R Aldrich-Wright, Dan Gibson. Probing the Interactions of Cytotoxic [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)] and Its PtIV Derivatives with Human Serum. ChemMedChem. 2017 04; 12(7):510-519. doi: 10.1002/cmdc.201700092. [PMID: 28206707]
  • Kiran Tummalapalli, Vasavi C S, Punnagai Munusami, Madhvesh Pathak, Balamurali M M. Evaluation of DNA/Protein interactions and cytotoxic studies of copper(II) complexes incorporated with N, N donor ligands and terpyridine ligand. International journal of biological macromolecules. 2017 Feb; 95(?):1254-1266. doi: 10.1016/j.ijbiomac.2016.11.022. [PMID: 27838416]
  • Leila Tabrizi, Hossein Chiniforoshan. New RuII pincer complexes: synthesis, characterization and biological evaluation for photodynamic therapy. Dalton transactions (Cambridge, England : 2003). 2016 Nov; 45(45):18333-18345. doi: 10.1039/c6dt03502g. [PMID: 27805201]
  • Shiori Nonaka, Tsutomu Katsuyama, Tatsuhiko Kondo, Yasuyuki Sasaki, Tadao Asami, Shunsuke Yajima, Shinsaku Ito. 1,10-Phenanthroline and its derivatives are novel hatching stimulants for soybean cyst nematodes. Bioorganic & medicinal chemistry letters. 2016 11; 26(21):5240-5243. doi: 10.1016/j.bmcl.2016.09.052. [PMID: 27692853]
  • Bo Peng, Zhuantao Gao, Xibo Li, Tingting Li, Guorong Chen, Min Zhou, Ji Zhang. DNA binding, DNA cleavage and HSA interaction of several metal complexes containing N-(2-hydroxyethyl)-N'-benzoylthiourea and 1,10-phenanthroline ligands. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2016 10; 21(7):903-16. doi: 10.1007/s00775-016-1388-1. [PMID: 27571992]
  • Spyros Perontsis, Antonios G Hatzidimitriou, Olga-Aggeliki Begou, Athanasios N Papadopoulos, George Psomas. Characterization and biological properties of copper(II)-ketoprofen complexes. Journal of inorganic biochemistry. 2016 09; 162(?):22-30. doi: 10.1016/j.jinorgbio.2016.06.001. [PMID: 27323214]
  • Spyros Perontsis, Antonios G Hatzidimitriou, Athanasios N Papadopoulos, George Psomas. Nickel-diflunisal complexes: synthesis, characterization, in vitro antioxidant activity and interaction with DNA and albumins. Journal of inorganic biochemistry. 2016 09; 162(?):9-21. doi: 10.1016/j.jinorgbio.2016.06.003. [PMID: 27318424]
  • Qiang Wei, Jianfang Dong, Peiran Zhao, Manman Li, Fengling Cheng, Jinming Kong, Lianzhi Li. DNA binding, BSA interaction and SOD activity of two new nickel(II) complexes with glutamine Schiff base ligands. Journal of photochemistry and photobiology. B, Biology. 2016 Aug; 161(?):355-67. doi: 10.1016/j.jphotobiol.2016.03.053. [PMID: 27295415]
  • Ying Xiao, Qing Wang, Yanmei Huang, Xiangling Ma, Xinnuo Xiong, Hui Li. Synthesis, structure, and biological evaluation of a copper(ii) complex with fleroxacin and 1,10-phenanthroline. Dalton transactions (Cambridge, England : 2003). 2016 Jul; 45(27):10928-35. doi: 10.1039/c6dt00915h. [PMID: 27301999]
  • Chew Hee Ng, Cheang Wei Chan, Jing Wei Lai, Ing Hong Ooi, Kok Vei Chong, Mohd Jamil Maah, Hoi Ling Seng. Enantiomeric pair of copper(II) polypyridyl-alanine complexes: Effect of chirality on their interaction with biomolecules. Journal of inorganic biochemistry. 2016 07; 160(?):1-11. doi: 10.1016/j.jinorgbio.2016.04.003. [PMID: 27105312]
  • B Annaraj, C Balakrishnan, M A Neelakantan. Synthesis, structure information, DNA/BSA binding affinity and in vitro cytotoxic studies of mixed ligand copper(II) complexes containing a phenylalanine derivative and diimine co-ligands. Journal of photochemistry and photobiology. B, Biology. 2016 Jul; 160(?):278-91. doi: 10.1016/j.jphotobiol.2016.04.021. [PMID: 27155593]
  • Sofia Tsiliou, Lida-Aikaterini Kefala, Antonios G Hatzidimitriou, Dimitris P Kessissoglou, Franc Perdih, Athanasios N Papadopoulos, Iztok Turel, George Psomas. Cobalt(II) complexes with non-steroidal anti-inflammatory drugs and α-diimines. Journal of inorganic biochemistry. 2016 07; 160(?):125-39. doi: 10.1016/j.jinorgbio.2015.12.015. [PMID: 26775611]
  • Veysel T Yilmaz, Ceyda Icsel, Feruza Suyunova, Muhittin Aygun, Nazlihan Aztopal, Engin Ulukaya. Ni(ii)/Cu(ii)/Zn(ii) 5,5-diethylbarbiturate complexes with 1,10-phenanthroline and 2,2'-dipyridylamine: synthesis, structures, DNA/BSA binding, nuclease activity, molecular docking, cellular uptake, cytotoxicity and the mode of cell death. Dalton transactions (Cambridge, England : 2003). 2016 Jun; 45(25):10466-79. doi: 10.1039/c6dt01726f. [PMID: 27263797]
  • Manideepa Saha, Mriganka Das, Rajendar Nasani, Indrani Choudhuri, Muhammed Yousufuddin, Hari Pada Nayek, Mobin M Shaikh, Biswarup Pathak, Suman Mukhopadhyay. Targeted water soluble copper-tetrazolate complexes: interactions with biomolecules and catecholase like activities. Dalton transactions (Cambridge, England : 2003). 2015 Dec; 44(46):20154-67. doi: 10.1039/c5dt01471a. [PMID: 26530012]
  • Marcela Queiroz Granato, Priscila de Araújo Massapust, Sonia Rozental, Celuta Sales Alviano, André Luis Souza dos Santos, Lucimar Ferreira Kneipp. 1,10-phenanthroline inhibits the metallopeptidase secreted by Phialophora verrucosa and modulates its growth, morphology and differentiation. Mycopathologia. 2015 Apr; 179(3-4):231-42. doi: 10.1007/s11046-014-9832-7. [PMID: 25502596]
  • Khan Behlol Ayaz Ahmed, Elamvazhuthi Reshma, Mariappan Mariappan, Veerappan Anbazhagan. Spectroscopic investigation on the interaction of ruthenium complexes with tumor specific lectin, jacalin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2015 Feb; 137(?):1292-7. doi: 10.1016/j.saa.2014.09.047. [PMID: 25306128]
  • Sang Phil Shin, Kosuke Zenke, Hiroshi Yokoyama, Tomoyoshi Yoshinaga. Factors affecting sporoplasm release in Kudoa septempunctata. Parasitology research. 2015 Feb; 114(2):795-9. doi: 10.1007/s00436-014-4305-y. [PMID: 25563617]
  • Essam Kotb. Characterization of a Thermostable Uricase Isolated from Bacillus firmus DWD-33 and its Application for Uric Acid Quantification in Human Serum. Protein and peptide letters. 2015; 22(5):402-9. doi: 10.2174/092986652205150509213536. [PMID: 25981580]
  • Sartaj Tabassum, Mehvash Zaki, Musheer Ahmad, Mohd Afzal, Saurabh Srivastav, Saripella Srikrishna, Farukh Arjmand. Synthesis and crystal structure determination of copper(II)-complex: In vitro DNA and HSA binding, pBR322 plasmid cleavage, cell imaging and cytotoxic studies. European journal of medicinal chemistry. 2014 Aug; 83(?):141-54. doi: 10.1016/j.ejmech.2014.06.018. [PMID: 24953031]
  • Essam Kotb. Purification and partial characterization of a chymotrypsin-like serine fibrinolytic enzyme from Bacillus amyloliquefaciens FCF-11 using corn husk as a novel substrate. World journal of microbiology & biotechnology. 2014 Jul; 30(7):2071-80. doi: 10.1007/s11274-014-1632-1. [PMID: 24609498]
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  • Nahid Shahabadi, Leila Nemati. Multispectroscopic studies on the interaction of a platinum(II) complex containing L-histidine and 1,10-phenanthroline ligands with bovine serum albumin. Applied biochemistry and biotechnology. 2014 Mar; 172(6):2800-14. doi: 10.1007/s12010-013-0715-z. [PMID: 24442907]
  • Wenzhu Zhang, Jingmei Zhang, Hailei Zhang, Liyan Cao, Run Zhang, Zhiqiang Ye, Jingli Yuan. Development and application of a ruthenium(II) complex-based photoluminescent and electrochemiluminescent dual-signaling probe for nitric oxide. Talanta. 2013 Nov; 116(?):354-60. doi: 10.1016/j.talanta.2013.05.064. [PMID: 24148415]
  • Andreea Prisecaru, Vickie McKee, Orla Howe, Garret Rochford, Malachy McCann, John Colleran, Milan Pour, Niall Barron, Nicholas Gathergood, Andrew Kellett. Regulating bioactivity of Cu2+ bis-1,10-phenanthroline artificial metallonucleases with sterically functionalized pendant carboxylates. Journal of medicinal chemistry. 2013 Nov; 56(21):8599-615. doi: 10.1021/jm401465m. [PMID: 24131470]
  • Lianzhi Li, Qiong Guo, Jianfang Dong, Tao Xu, Jinghong Li. DNA binding, DNA cleavage and BSA interaction of a mixed-ligand copper(II) complex with taurine Schiff base and 1,10-phenanthroline. Journal of photochemistry and photobiology. B, Biology. 2013 Aug; 125(?):56-62. doi: 10.1016/j.jphotobiol.2013.05.007. [PMID: 23748130]
  • Xin Liu, Xi Li, Zhijun Zhang, Yulin Dong, Peng Liu, Chaocan Zhang. Studies on antibacterial mechanisms of copper complexes with 1,10-phenanthroline and amino acid on Escherichia coli. Biological trace element research. 2013 Jul; 154(1):150-5. doi: 10.1007/s12011-013-9707-7. [PMID: 23716177]
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