DL-Leucine (BioDeep_00000398708)

   

natural product BioNovoGene_Lab2019


代谢物信息卡片


2-Amino-4-methylpentanoic acid

化学式: C6H13NO2 (131.0946)
中文名称: (±)-氨基-4-甲基戊酸, 聚L-亮氨酸, DL-亮氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CC(C(=O)O)N
InChI: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

描述信息

relative retention time with respect to 9-anthracene Carboxylic Acid is 0.062
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.057
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.055

同义名列表

3 个代谢物同义名

2-Amino-4-methylpentanoic acid; Poly-L-leucine; DL-Leucine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

154 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, CA3, CAT, EDN1, G6PD, NPPA, ODC1, TNK1, TUBB4B
Peripheral membrane protein 2 G6PD, TNK1
Endoplasmic reticulum membrane 1 HSP90B1
Nucleus 4 ALB, HSP90B1, JUN, TUBB4B
cytosol 7 ALB, CA3, CAT, G6PD, HSP90B1, ODC1, TUBB4B
centrosome 1 ALB
nucleoplasm 1 JUN
RNA polymerase II transcription regulator complex 1 JUN
Cell membrane 1 AGTR2
Multi-pass membrane protein 2 AGTR2, MPC1L
cell surface 1 APOH
Golgi apparatus 1 ALB
Golgi membrane 1 INS
lysosomal membrane 1 EGF
mitochondrial inner membrane 1 MPC1L
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 G6PD
plasma membrane 4 AGTR2, EGF, GCG, TNK1
Membrane 5 CAT, EGF, G6PD, HSP90B1, TNK1
extracellular exosome 7 ALB, APOH, CAT, EGF, G6PD, HSP90B1, TUBB4B
endoplasmic reticulum 2 ALB, HSP90B1
extracellular space 10 ALB, APOH, EDN1, EGF, GCG, GNRH1, INS, NPPA, PTH, TG
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 1 CAT
protein-containing complex 4 ALB, CAT, HSP90B1, NPPA
intracellular membrane-bounded organelle 2 CAT, G6PD
Secreted 7 ALB, APOH, EDN1, GCG, INS, NPPA, TG
extracellular region 13 ALB, APOH, CAT, EDN1, EGF, GCG, GNRH1, HSP90B1, INS, NPPA, PTH, TG, TUBB4B
cytoplasmic side of plasma membrane 1 G6PD
basal part of cell 1 EDN1
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
transcription regulator complex 1 JUN
centriolar satellite 1 G6PD
Extracellular vesicle 1 TUBB4B
chylomicron 1 APOH
high-density lipoprotein particle 1 APOH
very-low-density lipoprotein particle 1 APOH
perikaryon 1 NPPA
microtubule cytoskeleton 1 TUBB4B
midbody 1 HSP90B1
Mitochondrion inner membrane 1 MPC1L
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 2 CAT, HSP90B1
microtubule 1 TUBB4B
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 3 APOH, HSP90B1, NPPA
ciliary basal body 1 ALB
chromatin 1 JUN
cell projection 1 NPPA
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
centriole 1 ALB
spindle pole 1 ALB
nuclear chromosome 1 JUN
blood microparticle 1 ALB
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
endosome lumen 1 INS
axonemal microtubule 1 TUBB4B
Melanosome 1 HSP90B1
euchromatin 1 JUN
sperm plasma membrane 1 HSP90B1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, GCG, HSP90B1, INS
platelet alpha granule lumen 2 ALB, EGF
transport vesicle 2 EDN1, INS
azurophil granule lumen 1 TUBB4B
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 EGF
Sarcoplasmic reticulum lumen 1 HSP90B1
endocytic vesicle lumen 1 HSP90B1
transcription factor AP-1 complex 1 JUN
[Long-acting natriuretic peptide]: Secreted 1 NPPA
[Vessel dilator]: Secreted 1 NPPA
[Kaliuretic peptide]: Secreted 1 NPPA
[Urodilatin]: Secreted 1 NPPA
[Atrial natriuretic peptide]: Secreted 1 NPPA
[Atriopeptin-3]: Secreted 1 NPPA
[Glucagon-like peptide 1]: Secreted 1 GCG
platelet dense granule lumen 1 APOH
rough endoplasmic reticulum lumen 1 EDN1
catalase complex 1 CAT
Weibel-Palade body 1 EDN1
endoplasmic reticulum chaperone complex 1 HSP90B1
ciliary transition fiber 1 ALB


文献列表

  • N N Zashikhina, M V Volokitina, V A Korzhikov-Vlakh, I I Tarasenko, A Lavrentieva, T Scheper, E Rühl, R V Orlova, T B Tennikova, E G Korzhikova-Vlakh. Self-assembled polypeptide nanoparticles for intracellular irinotecan delivery. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2017 Nov; 109(?):1-12. doi: 10.1016/j.ejps.2017.07.022. [PMID: 28735041]
  • Angéla Juhász, Szabolcs Makai, Endre Sebestyén, László Tamás, Ervin Balázs. Role of conserved non-coding regulatory elements in LMW glutenin gene expression. PloS one. 2011; 6(12):e29501. doi: 10.1371/journal.pone.0029501. [PMID: 22242127]
  • Wei-Lung Tseng, Chih-Yao Hsu, Tsung-Han Wu, Shiou-Wen Huang, Ming-Mu Hsieh. Highly sensitive detection of chiral amino acids by CE based on on-line stacking techniques. Electrophoresis. 2009 Jul; 30(14):2558-64. doi: 10.1002/elps.200800765. [PMID: 19639576]
  • Shoucheng Pu, Yuanqiang Guo, Wenyuan Gao. [Chemical constituents from Centipeda minima]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Jun; 34(12):1520-2. doi: . [PMID: 19777837]
  • C Gervelas, A-L Serandour, S Geiger, G Grillon, P Fritsch, C Taulelle, B Le Gall, H Benech, J-R Deverre, E Fattal, N Tsapis. Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: effect on lung and systemic decorporation of plutonium. Journal of controlled release : official journal of the Controlled Release Society. 2007 Mar; 118(1):78-86. doi: 10.1016/j.jconrel.2006.11.027. [PMID: 17241685]
  • Victoria S Lim, Kevin E Yarasheski, Jan R Crowley, Jerry Fangman, Michael Flanigan. Insulin is protein-anabolic in chronic renal failure patients. Journal of the American Society of Nephrology : JASN. 2003 Sep; 14(9):2297-304. doi: 10.1097/01.asn.0000085590.83005.a0. [PMID: 12937306]
  • D Enders, J H Kirchhoff, J Köbberling, T H Peiffer. Asymmetric synthesis of alpha-branched primary amines on solid support via novel hydrazine resins. Organic letters. 2001 Apr; 3(8):1241-4. doi: 10.1021/ol015721x. [PMID: 11348204]