Morin (BioDeep_00000398503)

Main id: BioDeep_00000002489

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-

化学式: C15H10O7 (302.0427)
中文名称: 桑色素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
InChI: InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D020011 - Protective Agents > D000975 - Antioxidants
Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation[1][2].
Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation[1][2].

同义名列表

77 个代谢物同义名

4H-1-Benzopyran-4-one, 2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-; 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-; 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-chromenone; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone; 5-18-05-00492 (Beilstein Handbook Reference); Flavone, 2,3,4,5,7-pentahydroxy-; 2,4,5,7-Tetrahydroxyflavan-3-ol; 3,5,7,2,4-Pentahydroxyflavonol; 3,5,7,2,4-Pentahydroxyflavone; 2,4,3,5,7-Pentahydroxyflavone; 3,5 7 2 4-Pentahydroxyflavone; 2,3,4,5,7-pentahydroxyflavone; 2-Hydroxypelargidenolon 1522; C.I. Natural Yellow 11 (VAN); Zlut prirodni 11 [Czech]; C.I. Natural Yellow 11; SDCCGMLS-0003296.P003; C.I. Natural Yellow 8; Osage Orange Crystals; Osage orange extract; Bois darc [French]; Toxylon Pomiferum; Spectrum5_000737; Spectrum4_001924; Spectrum2_000715; Spectrum3_001941; EINECS 207-542-9; SPECTRUM1502259; NCGC00022214-05; NCGC00022214-04; Spectrum_001234; NCGC00015672-01; Calico Yellow; KBioGR_002268; DivK1c_000958; BSPBio_003541; KBioSS_001714; MEGxp0_001864; Lopac0_000776; Osage orange; KBio2_006850; NCI60_001647; Lopac-M-4008; SPBio_000929; ACon1_000260; ZINC03881558; KBio2_004282; MLS000069618; SMR000058259; KBio1_000958; KBio3_002824; KBio2_001714; NINDS_000958; SMP1_000199; BRN 0327474; 69870_FLUKA; AIDS-001407; IDI1_000958; AIDS001407; Bois d,Arc; 11128-85-1; C.I. 75660; EU-0100776; SBB008853; Aurantica; Bois darc; NSC 19801; AI3-38057; Al-Morin; NSC19801; 480-16-0; C10105; Morin; Morin



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

22 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AIMP2, BCL2, BIRC5, CASP3, CASP9, CAT, MAPK8, NFKBIA, PIK3CA, PTGS2, SGCB, SNCA, TLR4, XDH
Peripheral membrane protein 2 GORASP1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS2
Nucleus 11 AIMP2, BCL2, BIRC5, CASP3, CASP9, GABPA, HMOX1, JUND, MAPK8, NFKBIA, SNCA
cytosol 12 AIMP2, BCL2, BIRC5, CASP3, CASP9, CAT, HMOX1, MAPK8, NFKBIA, PIK3CA, SNCA, XDH
nucleoplasm 7 BIRC5, CASP3, GABPA, HMOX1, JUND, MAPK8, NFKBIA
RNA polymerase II transcription regulator complex 1 JUND
Cell membrane 2 TLR4, TNF
Cytoplasmic side 2 GORASP1, HMOX1
lamellipodium 1 PIK3CA
Cell projection, axon 1 SNCA
Multi-pass membrane protein 1 ABCC3
Golgi apparatus membrane 1 GORASP1
Synapse 2 MAPK8, SNCA
cell cortex 1 SNCA
cell surface 2 TLR4, TNF
glutamatergic synapse 1 CASP3
Golgi apparatus 1 GORASP1
Golgi membrane 1 GORASP1
growth cone 1 SNCA
neuronal cell body 3 CASP3, SNCA, TNF
postsynapse 1 SNCA
sarcolemma 1 SGCB
Cytoplasm, cytosol 1 AIMP2
Lysosome 1 SNCA
plasma membrane 7 ABCC3, NFKBIA, PIK3CA, SGCB, SNCA, TLR4, TNF
synaptic vesicle membrane 1 SNCA
Membrane 7 ABCC3, AIMP2, BCL2, CAT, HMOX1, SNCA, TLR4
axon 2 MAPK8, SNCA
basolateral plasma membrane 1 ABCC3
caveola 1 PTGS2
extracellular exosome 1 CAT
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 4 HMOX1, SNCA, TNF, XDH
perinuclear region of cytoplasm 4 HMOX1, PIK3CA, SNCA, TLR4
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, CASP9, CAT, SNCA
protein-containing complex 6 BCL2, BIRC5, CASP9, CAT, PTGS2, SNCA
intracellular membrane-bounded organelle 1 CAT
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 TLR4
Secreted 1 SNCA
extracellular region 3 CAT, SNCA, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 1 CAT
transcription regulator complex 1 JUND
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 TLR4, TNF
actin cytoskeleton 1 SNCA
microtubule cytoskeleton 1 BIRC5
midbody 1 BIRC5
Early endosome 1 TLR4
recycling endosome 1 TNF
Single-pass type II membrane protein 2 SGCB, TNF
Cell membrane, sarcolemma 1 SGCB
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 SGCB
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 1 CAT
microtubule 1 BIRC5
spindle 1 BIRC5
cis-Golgi network 1 GORASP1
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
interphase microtubule organizing center 1 BIRC5
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 1 PTGS2
chromatin 2 GABPA, JUND
phagocytic cup 2 TLR4, TNF
supramolecular fiber 1 SNCA
Chromosome 1 BIRC5
cytoskeleton 1 SGCB
centriole 1 BIRC5
nuclear chromosome 1 BIRC5
Basolateral cell membrane 1 ABCC3
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
myelin sheath 1 BCL2
basal plasma membrane 1 ABCC3
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 PTGS2
transcription repressor complex 1 JUND
axon terminus 1 SNCA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
kinetochore 1 BIRC5
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Single-pass type IV membrane protein 1 HMOX1
apoptosome 1 CASP9
chromosome, centromeric region 1 BIRC5
chromosome passenger complex 1 BIRC5
cytoplasmic microtubule 1 BIRC5
Basal cell membrane 1 ABCC3
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
dystrophin-associated glycoprotein complex 1 SGCB
sarcoglycan complex 1 SGCB
transcription factor AP-1 complex 1 JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
inclusion body 1 SNCA
BAD-BCL-2 complex 1 BCL2
I-kappaB/NF-kappaB complex 1 NFKBIA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Jia-Yi Zhou, Wen-Wen Xie, Ting-Cai Hu, Xiao-Fan Wang, Hui-Chao Yan, Xiu-Qi Wang. Mulberry Leaf-Derived Morin Activates β-Catenin by Binding to Frizzled7 to Promote Intestinal Stem Cell Expansion upon Heat-Stable Enterotoxin b Injury. Journal of agricultural and food chemistry. 2024 May; 72(18):10366-10375. doi: 10.1021/acs.jafc.3c09909. [PMID: 38651967]
  • Ziqi Hua, Yanfei Li, Tao Chen, Di Wu, Yu Xu, Jiang-Ning Hu. Morin-Based Nanoparticles for Regulation of Blood Glucose. ACS applied materials & interfaces. 2024 May; 16(17):21400-21414. doi: 10.1021/acsami.3c17642. [PMID: 38640094]
  • Arash Bahramzadeh, Sadra Samavarchi Tehrani, Golnaz Goodarzi, ShadiSadat Seyyedebrahimi, Reza Meshkani. Combination therapy of metformin and morin attenuates insulin resistance, inflammation, and oxidative stress in skeletal muscle of high-fat diet-fed mice. Phytotherapy research : PTR. 2024 Feb; 38(2):912-924. doi: 10.1002/ptr.8086. [PMID: 38091524]
  • Rahul Kumar, Vikash Kumar, Guruswami Gurusubramanian, Saurabh Singh Rathore, Vikas Kumar Roy. Morin hydrate ameliorates heat-induced testicular impairment in a mouse model. Molecular biology reports. 2024 Jan; 51(1):103. doi: 10.1007/s11033-023-09157-y. [PMID: 38219219]
  • Mervat F Zayed, Yasser K Abdel-Monem, Abeer A Arafa, Wael H Eisa. Mass production of morin-stabilized silver nanoparticles: Characterization, antioxidant, and antimicrobial activities. Microscopy research and technique. 2024 Jan; 87(1):149-158. doi: 10.1002/jemt.24419. [PMID: 37728192]
  • Mahima Singh, Ajay Guru, Raman Pachaiappan, Bader O Almutairi, Selvaraj Arokiyaraj, Muthukaruppan Gopi, Jesu Arockiaraj. Impact of butylparaben on β-cell damage and insulin/PEPCK expression in zebrafish larvae: Protective effects of morin. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23520. doi: 10.1002/jbt.23520. [PMID: 37632306]
  • Ibukun Mary Folorunso, Akeem Olalekan Lawal, Olusola Olalekan Elekofehinti, Opeyemi Iwaloye. Hepatoprotective Effect of Morin Hydrate in Type 2 Diabetic Wistar Rats Exposed to Diesel Exhaust Particles. Applied biochemistry and biotechnology. 2023 Oct; 195(10):5855-5880. doi: 10.1007/s12010-023-04366-4. [PMID: 36708492]
  • Xinxiu Ren, Qinfeng Guo, Hui Jiang, Xiao Han, Xiaoshi He, Haodong Liu, Zhilong Xiu, Yuesheng Dong. Combinational application of the natural products 1-deoxynojirimycin and morin ameliorates insulin resistance and lipid accumulation in prediabetic mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Sep; 121(?):155106. doi: 10.1016/j.phymed.2023.155106. [PMID: 37797432]
  • Lalrawngbawli Annie, Vanrohlu Nicy, Vanlal Rempuia, Chuckles Ch Marak, Guruswami Gurusubramanian, Vikas K Roy. Morin mitigates cadmium-induced testicular impairment by stimulating testosterone secretion and germ cell proliferation in mice. Journal of biochemical and molecular toxicology. 2023 Jun; ?(?):e23400. doi: 10.1002/jbt.23400. [PMID: 37335250]
  • Sadra Samavarchi Tehrani, Golnaz Goodarzi, Ghodratollah Panahi, Fahimeh Zamani-Garmsiri, Reza Meshkani. The combination of metformin with morin alleviates hepatic steatosis via modulating hepatic lipid metabolism, hepatic inflammation, brown adipose tissue thermogenesis, and white adipose tissue browning in high-fat diet-fed mice. Life sciences. 2023 Jun; 323(?):121706. doi: 10.1016/j.lfs.2023.121706. [PMID: 37075944]
  • Ziying Wang, Jinshuai Cui, Dongni Li, Shuzhen Ran, Junqing Huang, Gang Chen. Morin exhibits a neuroprotective effect in MPTP-induced Parkinson's disease model via TFEB/AMPK-mediated mitophagy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 May; 116(?):154866. doi: 10.1016/j.phymed.2023.154866. [PMID: 37209604]
  • Ola E Mohamed, Dalaal M Abdallah, Ahmed M Fayez, Reem A Mohamed, Hanan S El-Abhar. Morin post-treatment surpassed calpeptin in ameliorating 3-NP-induced cortical neurotoxicity via modulation of glutamate/calpain axis, Kidins220, and BDNF/TrkB/AKT/CREB trajectory. International immunopharmacology. 2023 Feb; 116(?):109771. doi: 10.1016/j.intimp.2023.109771. [PMID: 36736222]
  • Ravi Gor, Linkon Saha, Sparsh Agarwal, Urekha Karri, Advait Sohani, Thirumurthy Madhavan, Raman Pachaiappan, Satish Ramalingam. Morin inhibits colon cancer stem cells by inhibiting PUM1 expression in vitro. Medical oncology (Northwood, London, England). 2022 Oct; 39(12):251. doi: 10.1007/s12032-022-01851-4. [PMID: 36224472]
  • I O Ishola, I O Awogbindin, T G Olubodun-Obadun, O A Oluwafemi, J E Onuelu, O O Adeyemi. Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement. Brain research. 2022 08; 1789(?):147958. doi: 10.1016/j.brainres.2022.147958. [PMID: 35654119]
  • Anamika Gupta, Rumana Ahmad, Sahabjada Siddiqui, Kusum Yadav, Aditi Srivastava, Anchal Trivedi, Bilal Ahmad, Mohsin Ali Khan, Amit Kumar Shrivastava, Girish Kumar Singh. Flavonol morin targets host ACE2, IMP-α, PARP-1 and viral proteins of SARS-CoV-2, SARS-CoV and MERS-CoV critical for infection and survival: a computational analysis. Journal of biomolecular structure & dynamics. 2022 08; 40(12):5515-5546. doi: 10.1080/07391102.2021.1871863. [PMID: 33526003]
  • Selim Çomaklı, Fatih Mehmet Kandemir, Sefa Küçükler, Selçuk Özdemir. Morin mitigates ifosfamide induced nephrotoxicity by regulation of NF-kappaB/p53 and Bcl-2 expression. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2022 Aug; 97(6):423-432. doi: 10.1080/10520295.2021.2021449. [PMID: 35037524]
  • Praveen Kumar Issac, Manikandan Velayutham, Ajay Guru, Gokul Sudhakaran, Raman Pachaiappan, Jesu Arockiaraj. Protective effect of morin by targeting mitochondrial reactive oxygen species induced by hydrogen peroxide demonstrated at a molecular level in MDCK epithelial cells. Molecular biology reports. 2022 Jun; 49(6):4269-4279. doi: 10.1007/s11033-022-07261-z. [PMID: 35182324]
  • R L Shyma, S Mini. Neuroprotective effect of Morin via TrkB/Akt pathway against diabetes mediated oxidative stress and apoptosis in neuronal cells. Toxicology mechanisms and methods. 2022 May; ?(?):1-10. doi: 10.1080/15376516.2022.2065225. [PMID: 35414346]
  • Xichuan Li, Ce Wang, Jinqian Chen, Xia Hu, Hao Zhang, Zhiying Li, Bei Lan, Wei Zhang, Yanjun Su, Chunze Zhang. Potential interactions among myricetin and dietary flavonols through the inhibition of human UDP-glucuronosyltransferase in vitro. Toxicology letters. 2022 Apr; 358(?):40-47. doi: 10.1016/j.toxlet.2022.01.007. [PMID: 35063619]
  • Yi Yang, Jiuying Liu, Weiwei Xu. Naringenin and morin reduces insulin resistance and endometrial hyperplasia in the rat model of polycystic ovarian syndrome through enhancement of inflammation and autophagic apoptosis. Acta biochimica Polonica. 2022 Feb; 69(1):91-100. doi: 10.18388/abp.2020_5722. [PMID: 35143137]
  • Xinxin Gao, Jingnan Xu, Liqiang Jiang, Wei Liu, Hongrong Hong, Yuxiao Qian, Shurou Li, Wenlong Huang, Haiguang Zhao, Zhengtao Yang, Quan Liu, Zhengkai Wei. Morin alleviates aflatoxin B1-induced liver and kidney injury by inhibiting heterophil extracellular traps release, oxidative stress and inflammatory responses in chicks. Poultry science. 2021 Dec; 100(12):101513. doi: 10.1016/j.psj.2021.101513. [PMID: 34731740]
  • Praveen Kumar Issac, Ajay Guru, Manikandan Velayutham, Raman Pachaiappan, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Ki Choon Choi, Ramasamy Harikrishnan, Jesu Arockiaraj. Oxidative stress induced antioxidant and neurotoxicity demonstrated in vivo zebrafish embryo or larval model and their normalization due to morin showing therapeutic implications. Life sciences. 2021 Oct; 283(?):119864. doi: 10.1016/j.lfs.2021.119864. [PMID: 34358548]
  • Ling Yang, Na Cao, Yumeng Miao, Yue Dai, Zhifeng Wei. Morin Acts as a USP7 Inhibitor to Hold Back the Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes in a 'Prickle1-mTORC2' Dependent Manner. Molecular nutrition & food research. 2021 10; 65(19):e2100367. doi: 10.1002/mnfr.202100367. [PMID: 34331380]
  • Praveen Kumar Issac, Rupmanjari Karan, Ajay Guru, R Pachaiappan, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Ki Choon Choi, Ramasamy Harikrishnan, Jesu Arockia Raj. Insulin signaling pathway assessment by enhancing antioxidant activity due to morin using in vitro rat skeletal muscle L6 myotubes cells. Molecular biology reports. 2021 Aug; 48(8):5857-5872. doi: 10.1007/s11033-021-06580-x. [PMID: 34302266]
  • Nausheen Nazir, Muhammad Zahoor, Mohammad Nisar, Imran Khan, Riaz Ullah, Amal Alotaibi. Antioxidants Isolated from Elaeagnus umbellata (Thunb.) Protect against Bacterial Infections and Diabetes in Streptozotocin-Induced Diabetic Rat Model. Molecules (Basel, Switzerland). 2021 Jul; 26(15):. doi: 10.3390/molecules26154464. [PMID: 34361617]
  • Yanan Yan, Lin Li, Huilin Zhang, Fangfang Du, Yating Meng, Shaomin Shuang, Ruibing Wang, Shengmei Song, Chuan Dong. Carbon dots for ratiometric fluorescence detection of morin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jul; 256(?):119751. doi: 10.1016/j.saa.2021.119751. [PMID: 33819765]
  • Hatem M Abuohashish, Abdullah F AlAsmari, Mohamed Mohany, Mohammed M Ahmed, Salim S Al-Rejaie. Supplementation of Morin Restores the Altered Bone Histomorphometry in Hyperglycemic Rodents via Regulation of Insulin/IGF-1 Signaling. Nutrients. 2021 Jul; 13(7):. doi: 10.3390/nu13072365. [PMID: 34371877]
  • Arijit Mondal, Tapan Kumar Maity. Isolation of cytotoxic monomeric protein and morin derivatives from Solena amplexicaulis (Lam.) Gandhi. Natural product research. 2021 Jun; 35(12):2086-2089. doi: 10.1080/14786419.2019.1652287. [PMID: 31429296]
  • Shahid Ali Rajput, Xiu-Qi Wang, Hui-Chao Yan. Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jun; 138(?):111511. doi: 10.1016/j.biopha.2021.111511. [PMID: 33744757]
  • Abdallah Gendy, Mohamed R Elnagar, Ayman Soubh, Asmaa Al-Mokaddem, Alaadin El-Haddad, Mohamed Kotb El-Sayed. Morin alleviates hepatic ischemia/reperfusion-induced mischief: In vivo and in silico contribution of Nrf2, TLR4, and NLRP3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jun; 138(?):111539. doi: 10.1016/j.biopha.2021.111539. [PMID: 34311537]
  • Anbu Singaravelu, Karthikkumar Venkatachalam, Richard L Jayaraj, Padma Jayabalan, Saravanan Nadanam. Morin treatment for acute ethanol exposure in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2021 Apr; 96(3):230-241. doi: 10.1080/10520295.2020.1785548. [PMID: 32597243]
  • Shengjie Fan, Haiyan Zhang, Yahui Wang, Yuanyuan Zhao, Lingling Luo, Hongrun Wang, Gen Chen, Lianjun Xing, Peiyong Zheng, Cheng Huang. LXRα/β Antagonism Protects against Lipid Accumulation in the Liver but Increases Plasma Cholesterol in Rhesus Macaques. Chemical research in toxicology. 2021 03; 34(3):833-838. doi: 10.1021/acs.chemrestox.0c00445. [PMID: 33647205]
  • Ya-Jun Sun, Yan-Fang Zhang, Hui-Min Xu, Yong-Tao Ma, Chun Li, Chun-Hong Nie, Min Zhao. [Morin Improves Experimental Autoimmune Thyroiditis in Rats via NLRP3/Caspase-1 Pathway]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2021 Mar; 52(2):229-234. doi: 10.12182/20210160507. [PMID: 33829696]
  • Solaipriya Solairaja, Mohammad Qasim Andrabi, Nageswara Rao Dunna, Sivaramakrishnan Venkatabalasubramanian. Overview of Morin and Its Complementary Role as an Adjuvant for Anticancer Agents. Nutrition and cancer. 2021; 73(6):927-942. doi: 10.1080/01635581.2020.1778747. [PMID: 32530303]
  • Mahendra Pal Singh, Chanchal Sharma, Sun Chul Kang. Morin hydrate attenuates adenine-induced renal fibrosis via targeting cathepsin D signaling. International immunopharmacology. 2021 Jan; 90(?):107234. doi: 10.1016/j.intimp.2020.107234. [PMID: 33310295]
  • Ebenezer Tunde Olayinka, Kayode Ezekiel Adewole. Ameliorative effect of morin on dutasteride-tamsulosin-induced testicular oxidative stress in rat. Journal of complementary & integrative medicine. 2020 Dec; 18(2):327-337. doi: 10.1515/jcim-2019-0160. [PMID: 34187124]
  • Itzel Ivonn López-Tenorio, Aarón Domínguez-López, Ángel Miliar-García, Gerardo Norberto Escalona-Cardoso, Samantha Alejandra Real-Sandoval, Alejandro Gómez-Alcalá, María Eugenia Jaramillo-Flores. Modulation of the mRNA of the Nlrp3 inflammasome by Morin and PUFAs in an obesity model induced by a high-fat diet. Food research international (Ottawa, Ont.). 2020 11; 137(?):109706. doi: 10.1016/j.foodres.2020.109706. [PMID: 33233280]
  • Swathi Karamchedu, Lakshmi Tunki, Hitesh Kulhari, Deep Pooja. Morin hydrate loaded solid lipid nanoparticles: Characterization, stability, anticancer activity, and bioavailability. Chemistry and physics of lipids. 2020 11; 233(?):104988. doi: 10.1016/j.chemphyslip.2020.104988. [PMID: 33035545]
  • Hany H Arab, Muhammed A Saad, Ayman E El-Sahar, Muhammad Y Al-Shorbagy. Mechanistic perspective of morin protection against ketoprofen-induced gastric mucosal injury: Targeting HMGB1/RAGE/NF-κB, DJ-1/Nrf2/HO-1 and PI3K/mTOR pathways. Archives of biochemistry and biophysics. 2020 10; 693(?):108552. doi: 10.1016/j.abb.2020.108552. [PMID: 32860758]
  • Kiran Thakur, Yun-Yang Zhu, Jing-Yu Feng, Jian-Guo Zhang, Fei Hu, Chandan Prasad, Zhao-Jun Wei. Morin as an imminent functional food ingredient: an update on its enhanced efficacy in the treatment and prevention of metabolic syndromes. Food & function. 2020 Oct; 11(10):8424-8443. doi: 10.1039/d0fo01444c. [PMID: 33043925]
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  • Chitra Dhanasekar, Mahaboobkhan Rasool. Morin, a dietary bioflavonol suppresses monosodium urate crystal-induced inflammation in an animal model of acute gouty arthritis with reference to NLRP3 inflammasome, hypo-xanthine phospho-ribosyl transferase, and inflammatory mediators. European journal of pharmacology. 2016 Sep; 786(?):116-127. doi: 10.1016/j.ejphar.2016.06.005. [PMID: 27268719]
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  • Atanu Singha Roy, Sintu Kumar Samanta, Pooja Ghosh, Debi Ranjan Tripathy, Sudip Kumar Ghosh, Swagata Dasgupta. Cell cytotoxicity and serum albumin binding capacity of the morin-Cu(ii) complex and its effect on deoxyribonucleic acid. Molecular bioSystems. 2016 08; 12(9):2818-33. doi: 10.1039/c6mb00344c. [PMID: 27345944]
  • Sona Franova, Ivana Kazimierova, Lenka Pappova, Marta Joskova, Lukas Plank, Martina Sutovska. Bronchodilatory, antitussive and anti-inflammatory effect of morin in the setting of experimentally induced allergic asthma. The Journal of pharmacy and pharmacology. 2016 Aug; 68(8):1064-72. doi: 10.1111/jphp.12576. [PMID: 27283356]
  • Jarinyaporn Naowaboot, Supaporn Wannasiri, Patchareewan Pannangpetch. Morin attenuates hepatic insulin resistance in high-fat-diet-induced obese mice. Journal of physiology and biochemistry. 2016 Jun; 72(2):269-80. doi: 10.1007/s13105-016-0477-5. [PMID: 26976296]
  • Alpana Mathur, Fatima Rizvi, Poonam Kakkar. PHLPP2 down regulation influences nuclear Nrf2 stability via Akt-1/Gsk3β/Fyn kinase axis in acetaminophen induced oxidative renal toxicity: Protection accorded by morin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2016 Mar; 89(?):19-31. doi: 10.1016/j.fct.2016.01.001. [PMID: 26767949]