Spectinomycin (BioDeep_00000398457)

Main id: BioDeep_00000002645

 

natural product


代谢物信息卡片


Spectinomycin

化学式: C14H24N2O7 (332.1583)
中文名称: 大观霉素
谱图信息: 最多检出来源 Homo sapiens(urine) 11.83%

分子结构信息

SMILES: CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O
InChI: InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3

描述信息

A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.046
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.045

同义名列表

3 个代谢物同义名

Spectinomycin; Spectinomycin; Spectinomycin



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

47 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 CST3, DHFR, INSM2, MAPK8IP1, RPL15, RPS12, RPS5, RPS7, SAT1, SAT2
Golgi apparatus, trans-Golgi network membrane 1 ATP2C1
Peripheral membrane protein 1 CYP27A1
Endoplasmic reticulum membrane 2 MAPK8IP1, SPCS2
Mitochondrion membrane 1 CYP27A1
Nucleus 6 ACACB, INSM2, MAPK8IP1, RPL15, RPS7, SLC25A6
cytosol 9 ACACB, DHFR, MAPK8IP1, MTRR, RPL15, RPS12, RPS5, RPS7, SAT1
dendrite 2 MAPK8IP1, SAT2
mitochondrial membrane 1 MAPK8IP1
trans-Golgi network 1 ATP2C1
centrosome 1 RPS7
nucleoplasm 4 MTRR, RPS12, RPS5, RPS7
Cell membrane 2 SAT1, SAT2
Multi-pass membrane protein 6 ATP2C1, RHO, SAT1, SAT2, SLC25A6, SPCS2
Synapse 4 MAPK8IP1, RPL15, RPS5, RPS7
Golgi apparatus 4 ATP2C1, CST3, RHO, RPS12
Golgi membrane 2 ATP2C1, RHO
mitochondrial inner membrane 2 CYP27A1, SLC25A6
neuronal cell body 3 MAPK8IP1, SAT1, SAT2
sarcolemma 1 SAT2
Cytoplasm, cytosol 1 SAT1
endosome 1 UEVLD
plasma membrane 6 ATP2C1, CST3, MAPK8IP1, RHO, SAT1, SAT2
Membrane 7 ATP2C1, RHO, RPS12, RPS5, RPS7, SAT1, SLC25A6
axon 2 SAT1, SAT2
basolateral plasma membrane 1 SAT1
brush border 1 SAT2
extracellular exosome 6 CST3, RPS5, SAT1, SAT2, SPINK1, UEVLD
endoplasmic reticulum 3 ATP2C1, CST3, RPS7
extracellular space 2 CRP, CST3
perinuclear region of cytoplasm 1 MAPK8IP1
mitochondrion 4 ACACB, CYP27A1, DHFR, SLC25A6
protein-containing complex 1 RPS7
intracellular membrane-bounded organelle 1 RPS12
Secreted 3 CRP, CST3, SPINK1
extracellular region 2 CRP, CST3
mitochondrial outer membrane 1 ACACB
mitochondrial matrix 1 CYP27A1
ciliary membrane 1 RHO
photoreceptor inner segment 1 RHO
photoreceptor outer segment 1 RHO
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 RPS7
nucleolus 3 RPS12, RPS5, RPS7
cell-cell junction 1 RHO
vesicle 1 CST3
Cytoplasm, perinuclear region 1 MAPK8IP1
Mitochondrion inner membrane 2 CYP27A1, SLC25A6
focal adhesion 2 RPS5, RPS7
Cell projection, cilium, photoreceptor outer segment 1 RHO
Nucleus, nucleolus 3 RPS12, RPS5, RPS7
ESCRT I complex 1 UEVLD
sperm midpiece 1 RHO
Basolateral cell membrane 1 SAT1
Golgi cisterna membrane 1 ATP2C1
Golgi-associated vesicle membrane 1 RHO
intermediate filament cytoskeleton 1 MTRR
ficolin-1-rich granule lumen 1 CST3
endoplasmic reticulum lumen 1 CST3
transcription repressor complex 1 INSM2
Photoreceptor inner segment membrane 1 RHO
tertiary granule lumen 1 CST3
Golgi apparatus, Golgi stack membrane 1 ATP2C1
small-subunit processome 3 RPS12, RPS5, RPS7
mitochondrial fatty acid beta-oxidation multienzyme complex 1 ACACB
TIM23 mitochondrial import inner membrane translocase complex 1 SLC25A6
A band 1 RPL15
ribonucleoprotein complex 2 RPS5, RPS7
external side of apical plasma membrane 1 SAT1
photoreceptor outer segment membrane 1 RHO
sperm head plasma membrane 1 RHO
cis-Golgi network membrane 1 ATP2C1
cytosolic ribosome 4 RPL15, RPS12, RPS5, RPS7
photoreceptor disc membrane 1 RHO
ribosome 3 RPL15, RPS5, RPS7
cytosolic large ribosomal subunit 1 RPL15
rod photoreceptor outer segment 1 RHO
cytosolic small ribosomal subunit 3 RPS12, RPS5, RPS7
signal peptidase complex 1 SPCS2
small ribosomal subunit 1 RPS5
[Isoform A]: Cytoplasm 1 MTRR
dentate gyrus mossy fiber 1 MAPK8IP1
ribosomal subunit 1 RPL15


文献列表

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