trans-Zeatin (BioDeep_00000398057)

Main id: BioDeep_00000000727

Secondary id: BioDeep_00000406332

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


trans-Zeatin

化学式: C10H13N5O (219.112)
中文名称: 反-玉米素, 反式玉米素(tZ)
谱图信息: 最多检出来源 Viridiplantae(plant) 10.43%

分子结构信息

SMILES: C/C(=C\CNC1=NC=NC2=C1NC=N2)/CO
InChI: InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)

描述信息

The trans-isomer of zeatin.
(e)-zeatin, also known as (E)-2-methyl-4-(1h-purin-6-ylamino)-2-buten-1-ol or n6-(4-hydroxyisopentenyl)adenine, is a member of the class of compounds known as 6-alkylaminopurines. 6-alkylaminopurines are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring (e)-zeatin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (e)-zeatin can be found in a number of food items such as chia, cornmint, java plum, and small-leaf linden, which makes (e)-zeatin a potential biomarker for the consumption of these food products.
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D003583 - Cytokinins
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 24
INTERNAL_ID 24; CONFIDENCE Reference Standard (Level 1)
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.451
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.449
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.442
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.444
Acquisition and generation of the data is financially supported by the Max-Planck-Society
CONFIDENCE standard compound; ML_ID 56
trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.

同义名列表

2 个代谢物同义名

trans-Zeatin; Zeatin



数据库引用编号

85 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(4)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

30 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CAT, CRY2, DLK1, GLUL, HPGDS, MATK, PGR, PNP, TXN
Peripheral membrane protein 1 HSD17B6
Endoplasmic reticulum membrane 2 HMGCR, HSP90B1
Nucleus 9 ADK, CRY2, GLRX, GLUL, HNRNPM, HSP90B1, MYB, PGR, TXN
cytosol 13 ADK, CAT, CRY2, GLRX, GLUL, GSR, HPGDS, HSP90B1, MATK, MYB, PGR, PNP, TXN
nucleoplasm 7 ADK, CD2, HNRNPM, HPGDS, MYB, PGR, TXN
RNA polymerase II transcription regulator complex 1 MYB
Cell membrane 3 CD2, EMB, GLUL
Lipid-anchor 1 GLUL
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 HMGCR
Synapse 2 EMB, HNRNPM
cell surface 1 CD2
Golgi apparatus 1 CD2
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 GLUL
plasma membrane 7 ADK, CD2, EMB, GLUL, MATK, NPR1, PGR
Membrane 9 CAT, DLK1, EMB, HMGCR, HNRNPM, HSP90B1, MATK, MYB, NPR1
axon 1 EMB
extracellular exosome 8 CAT, GLRX, GLUL, GSR, HNRNPM, HSP90B1, PNP, TXN
Lumenal side 1 HSD17B6
endoplasmic reticulum 4 GLUL, HMGCR, HSD17B6, HSP90B1
extracellular space 2 DLK1, PNP
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 4 CAT, CRY2, GLUL, GSR
protein-containing complex 3 CAT, CD2, HSP90B1
intracellular membrane-bounded organelle 3 CAT, HPGDS, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 2 CD2, EMB
Secreted 2 PNP, TXN
extracellular region 6 CAT, CD2, CRY2, HSP90B1, PNP, TXN
cytoplasmic side of plasma membrane 1 CD2
Single-pass membrane protein 1 DLK1
mitochondrial outer membrane 1 PGR
mitochondrial matrix 2 CAT, GSR
external side of plasma membrane 2 CD2, GSR
nucleolus 1 HNRNPM
midbody 1 HSP90B1
cell-cell junction 1 CD2
focal adhesion 2 CAT, HSP90B1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 2 CAT, HMGCR
collagen-containing extracellular matrix 2 HNRNPM, HSP90B1
nuclear speck 1 CRY2
receptor complex 1 NPR1
chromatin 1 PGR
spliceosomal complex 1 HNRNPM
Melanosome 1 HSP90B1
cell body 1 GLUL
sperm plasma membrane 1 HSP90B1
Peroxisome membrane 1 HMGCR
Microsome 1 GLUL
ficolin-1-rich granule lumen 2 CAT, PNP
secretory granule lumen 2 CAT, PNP
endoplasmic reticulum lumen 1 HSP90B1
nuclear matrix 2 HNRNPM, MYB
[Isoform 2]: Cytoplasm 1 ADK
Sarcoplasmic reticulum lumen 1 HSP90B1
[Isoform 1]: Nucleus 1 ADK
Cry-Per complex 1 CRY2
catalytic step 2 spliceosome 1 HNRNPM
paraspeckles 1 HNRNPM
glial cell projection 1 GLUL
endocytic vesicle lumen 1 HSP90B1
catalase complex 1 CAT
[Isoform 4]: Mitochondrion outer membrane 1 PGR
endoplasmic reticulum chaperone complex 1 HSP90B1
ANPR-A receptor complex 1 NPR1


文献列表

  • Tatyana V Nuzhnaya, Antonina V Sorokan, Guzel F Burkhanova, Igor V Maksimov, Svetlana V Veselova. The Role of Cytokinins and Abscisic Acid in the Growth, Development and Virulence of the Pathogenic Fungus Stagonospora nodorum (Berk.). Biomolecules. 2024 Apr; 14(5):. doi: 10.3390/biom14050517. [PMID: 38785924]
  • Wenzhe Yu, Li Luo, Xiangyu Qi, Yuman Cao, Jie An, Zhiguo Xie, Tianming Hu, Peizhi Yang. Insights into the Impact of Trans-Zeatin Overproduction-Engineered Sinorhizobium meliloti on Alfalfa (Medicago sativa L.) Tolerance to Drought Stress. Journal of agricultural and food chemistry. 2024 Apr; 72(15):8650-8663. doi: 10.1021/acs.jafc.4c00115. [PMID: 38564678]
  • Alicja Piotrowska-Niczyporuk, Elżbieta Bonda-Ostaszewska, Andrzej Bajguz. Mitigating Effect of Trans-Zeatin on Cadmium Toxicity in Desmodesmus armatus. Cells. 2024 Apr; 13(8):. doi: 10.3390/cells13080686. [PMID: 38667301]
  • Xiaomin Ren, Chenkai Yang, Xianxin Zhu, Pengfei Yi, Xizhen Jiang, Jiashuo Yang, Shipeng Xiang, Yunxia Li, Bei Yu, Weijie Yan, Xiaoxu Li, Yangyang Li, Risheng Hu, Zhengrong Hu. Insights into drought stress response mechanism of tobacco during seed germination by integrated analysis of transcriptome and metabolome. Plant physiology and biochemistry : PPB. 2024 Apr; 209(?):108526. doi: 10.1016/j.plaphy.2024.108526. [PMID: 38537383]
  • Xin Sun, Jiang-Zhe Zhao, Chuan-Shuo Wu, Ke-Wei Zhang, Liang Cheng. Flavin mononucleotide regulated photochemical isomerization and degradation of zeatin. Organic & biomolecular chemistry. 2024 03; 22(10):2021-2026. doi: 10.1039/d4ob00028e. [PMID: 38372990]
  • Peng Li, Zhiqiang Wang, Xiaodi Wang, Fengzhi Liu, Haibo Wang. Changes in Phytohormones and Transcriptomic Reprogramming in Strawberry Leaves under Different Light Qualities. International journal of molecular sciences. 2024 Feb; 25(5):. doi: 10.3390/ijms25052765. [PMID: 38474012]
  • Song Yu, Afsheen Zehra, Zulfiqar Ali Sahito, Wenkai Wang, Shaoning Chen, Ying Feng, Zhenli He, Xiaoe Yang. Cytokinin-mediated shoot proliferation and its correlation with phytoremediation effects in Cd-hyperaccumulator ecotype of Sedum alfredii. The Science of the total environment. 2024 Feb; 912(?):168993. doi: 10.1016/j.scitotenv.2023.168993. [PMID: 38043818]
  • Alberto Martinez-Alonso, Lucia Yepes-Molina, Angel L Guarnizo, Micaela Carvajal. Modification of Gene Expression of Tomato Plants through Foliar Flavonoid Application in Relation to Enhanced Growth. Genes. 2023 Dec; 14(12):. doi: 10.3390/genes14122208. [PMID: 38137030]
  • Dhananjaya Pratap Singh, Sudarshan Maurya, Suresh Reddy Yerasu, Mansi Singh Bisen, Mohamed A Farag, Ratna Prabha, Renu Shukla, Krishna Kumar Chaturvedi, Md Samir Farooqi, Sudhir Srivastava, Anil Rai, Birinchi Kumar Sarma, Nagendra Rai, Tusar Kanti Behera. Metabolomics of early blight (Alternaria solani) susceptible tomato (Solanum lycopersicum) unfolds key biomarker metabolites and involved metabolic pathways. Scientific reports. 2023 11; 13(1):21023. doi: 10.1038/s41598-023-48269-0. [PMID: 38030710]
  • Chenfei Huang, Xiaoling Jin, Haiyan Lin, Jinsong He, Yan Chen. Comparative Transcriptome Sequencing and Endogenous Phytohormone Content of Annual Grafted Branches of Zelkova schneideriana and Its Dwarf Variety HenTianGao. International journal of molecular sciences. 2023 Nov; 24(23):. doi: 10.3390/ijms242316902. [PMID: 38069226]
  • Erying Chen, Ling Qin, Feifei Li, Yanbing Yang, Zhenyu Liu, Runfeng Wang, Xiao Yu, Jiahong Niu, Huawen Zhang, Hailian Wang, Bin Liu, Yanan Guan. Physiological and Transcriptomic Analysis Provides Insights into Low Nitrogen Stress in Foxtail Millet (Setaria italica L.). International journal of molecular sciences. 2023 Nov; 24(22):. doi: 10.3390/ijms242216321. [PMID: 38003509]
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  • Takatoshi Kiba, Kahori Mizutani, Aimi Nakahara, Yumiko Takebayashi, Mikiko Kojima, Tokunori Hobo, Yuriko Osakabe, Keishi Osakabe, Hitoshi Sakakibara. The trans-zeatin-type side-chain modification of cytokinins controls rice growth. Plant physiology. 2023 Mar; ?(?):. doi: 10.1093/plphys/kiad197. [PMID: 36994817]
  • Yuexia Wang, Menghan Zhang, Xiaoyan Li, Ruixiang Zhou, Xinyu Xue, Jing Zhang, Nana Liu, Ruili Xue, Xueli Qi. Overexpression of the Wheat TaPsb28 Gene Enhances Drought Tolerance in Transgenic Arabidopsis. International journal of molecular sciences. 2023 Mar; 24(6):. doi: 10.3390/ijms24065226. [PMID: 36982301]
  • Paula Elizabeth Jameson. Zeatin: The 60th anniversary of its identification. Plant physiology. 2023 Feb; ?(?):. doi: 10.1093/plphys/kiad094. [PMID: 36789623]
  • Pipeng Xing, Haowen Luo, Zhenzhen He, Longxin He, Hua Zhao, Xiangru Tang, Meiyang Duan. Trans-Zeatin induce regulation the biosynthesis of 2-acetyl-1-pyrroline in fragrant rice (Oryza sativa L.) seedlings. BMC plant biology. 2023 Feb; 23(1):88. doi: 10.1186/s12870-023-04106-0. [PMID: 36765297]
  • Juan Qi, Zhaolin Wu, Yanjun Liu, Xiangjun Meng. Effects of plant age on antioxidant activity and endogenous hormones in Alpine Elymus sibiricus of the Tibetan Plateau. PeerJ. 2023; 11(?):e15150. doi: 10.7717/peerj.15150. [PMID: 37065700]
  • Leila Mirjani, Azam Salimi, Maryam Shahbazi, Mohammad-Reza Hajirezaei, Mohammad Matinizadeh, Khadijeh Razavi, Seyed Mohsen Hesamzadeh Hejazi. Arbuscular mycorrhizal colonization leads to a change of hormone profile in micropropagated plantlet Satureja khuzistanica Jam. Journal of plant physiology. 2023 Jan; 280(?):153879. doi: 10.1016/j.jplph.2022.153879. [PMID: 36516535]
  • Hongyi Zhang, Xiaohua Ou, Wenyi Chen, Qing Zeng, Yaling Yan, Mengling He, Hanjing Yan. Comparative physicochemical, hormonal, transcriptomic and proteomic analyses provide new insights into the formation mechanism of two chemotypes of Pogostemon cablin. PloS one. 2023; 18(9):e0290402. doi: 10.1371/journal.pone.0290402. [PMID: 37738267]
  • Man Zhang, Xiaojiao Chen, Yajie Zhao, Jiaqi Zhang, Qingqing He, Jingqi Qian, Guiyu Tan, Wei Liu, Xiaoling Yang, Baomin Wang. Quantification of six types of cytokinins: Integration of an ultra-performance liquid chromatographic-electrospray tandem mass spectrometric method with antibody based immunoaffinity columns equally recognizing cytokinins in free base and nucleoside forms. Journal of chromatography. A. 2022 Oct; 1682(?):463497. doi: 10.1016/j.chroma.2022.463497. [PMID: 36166882]
  • Hendrik Willem Swiegers, Barbara Karpinska, Yan Hu, Ian C Dodd, Anna-Maria Botha, Christine H Foyer. The Effects of High CO2 and Strigolactones on Shoot Branching and Aphid-Plant Compatibility Control in Pea. International journal of molecular sciences. 2022 Oct; 23(20):. doi: 10.3390/ijms232012160. [PMID: 36293014]
  • Ziqian Cui, Shaodong Liu, Changwei Ge, Qian Shen, Siping Zhang, Huijuan Ma, Ruihua Liu, Xinhua Zhao, Ruida Liu, Pengzhen Li, Hongchen Wang, Qidi Wu, Chaoyou Pang, Jing Chen. Genome-wide association study reveals that GhTRL1 and GhPIN8 affect cotton root development. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2022 Sep; 135(9):3161-3176. doi: 10.1007/s00122-022-04177-x. [PMID: 35965278]
  • Agata Ptak, Emilia Morańska, Marzena Warchoł, Artur Gurgul, Edyta Skrzypek, Michał Dziurka, Dominique Laurain-Mattar, Rosella Spina, Anita Jaglarz, Magdalena Simlat. Endophytic bacteria from in vitro culture of Leucojum aestivum L. a new source of galanthamine and elicitor of alkaloid biosynthesis. Scientific reports. 2022 08; 12(1):13700. doi: 10.1038/s41598-022-17992-5. [PMID: 35953692]
  • Carolina Falcato Fialho Palma, Victor Castro-Alves, Luis Orlando Morales, Eva Rosenqvist, Carl-Otto Ottosen, Tuulia Hyötyläinen, Åke Strid. Metabolic changes in cucumber leaves are enhanced by blue light but differentially affected by UV interactions with light signalling pathways in the visible spectrum. Plant science : an international journal of experimental plant biology. 2022 Aug; 321(?):111326. doi: 10.1016/j.plantsci.2022.111326. [PMID: 35696926]
  • N S Raja Gopalan, Raunak Sharma, Sridev Mohapatra. Probing into the unique relationship between a soil bacterium, Pseudomonas putida AKMP7 and Arabidopsis thaliana: A case of "conditional pathogenesis". Plant physiology and biochemistry : PPB. 2022 Jul; 183(?):46-55. doi: 10.1016/j.plaphy.2022.05.003. [PMID: 35567874]
  • Da-Li Geng, Heng Lu, Wei Liu, Lan-Ping Guo, Xiao Wang. [Winter pruning boosts growth and yield of Lonicera japonica by regulating plant hormone content]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Jul; 47(14):3749-3755. doi: 10.19540/j.cnki.cjcmm.20220416.102. [PMID: 35850831]
  • Klára Ptošková, Marek Szecówka, Pavel Jaworek, Danuše Tarkowská, Ivan Petřík, Iva Pavlović, Ondřej Novák, Stephen G Thomas, Andrew L Phillips, Peter Hedden. Changes in the concentrations and transcripts for gibberellins and other hormones in a growing leaf and roots of wheat seedlings in response to water restriction. BMC plant biology. 2022 Jun; 22(1):284. doi: 10.1186/s12870-022-03667-w. [PMID: 35676624]
  • Maria Breygina, Alexander Voronkov, Ilshat Galin, Guzel Akhiyarova, Svetlana Polevova, Ekaterina Klimenko, Igor Ivanov, Guzel Kudoyarova. Dynamics of endogenous levels and subcellular localization of ABA and cytokinins during pollen germination in spruce and tobacco. Protoplasma. 2022 May; ?(?):. doi: 10.1007/s00709-022-01766-x. [PMID: 35579760]
  • Jun Li, Chongmin Wang, Tao Zhou, Haijun Jin, Xiaoqing Liu. Identification and characterization of miRNAome and target genes in Pseudostellaria heterophylla. PloS one. 2022; 17(10):e0275566. doi: 10.1371/journal.pone.0275566. [PMID: 36197881]
  • Yuepeng Song, Panfei Chen, Anran Xuan, Chenhao Bu, Peng Liu, Pär K Ingvarsson, Yousry A El-Kassaby, Deqiang Zhang. Integration of genome wide association studies and co-expression networks reveal roles of PtoWRKY 42-PtoUGT76C1-1 in trans-zeatin metabolism and cytokinin sensitivity in poplar. The New phytologist. 2021 08; 231(4):1462-1477. doi: 10.1111/nph.17469. [PMID: 33999454]
  • Reiner Eidelpes, Florian Hofer, Manuel Röck, Sebastian Führer, Anna Sophia Kamenik, Klaus R Liedl, Martin Tollinger. Structure and Zeatin Binding of the Peach Allergen Pru p 1. Journal of agricultural and food chemistry. 2021 Jul; 69(29):8120-8129. doi: 10.1021/acs.jafc.1c01876. [PMID: 34260238]
  • Mat Yunus Najhah, Hawa Z E Jaafar, Jaafar Juju Nakasha, Mansor Hakiman. Shoot Multiplication and Callus Induction of Labisia pumila var. alata as Influenced by Different Plant Growth Regulators Treatments and Its Polyphenolic Activities Compared with the Wild Plant. Molecules (Basel, Switzerland). 2021 May; 26(11):. doi: 10.3390/molecules26113229. [PMID: 34072168]
  • Tatjana Ćosić, Václav Motyka, Jelena Savić, Martin Raspor, Marija Marković, Petre I Dobrev, Slavica Ninković. Sucrose interferes with endogenous cytokinin homeostasis and expression of organogenesis-related genes during de novo shoot organogenesis in kohlrabi. Scientific reports. 2021 03; 11(1):6494. doi: 10.1038/s41598-021-85932-w. [PMID: 33753792]
  • Tomáš Hluska, Lucia Hlusková, R J Neil Emery. The Hulks and the Deadpools of the Cytokinin Universe: A Dual Strategy for Cytokinin Production, Translocation, and Signal Transduction. Biomolecules. 2021 02; 11(2):. doi: 10.3390/biom11020209. [PMID: 33546210]
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  • Manuel Frank, Anne Cortleven, Ondřej Novák, Thomas Schmülling. Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod stress. Plant, cell & environment. 2020 11; 43(11):2637-2649. doi: 10.1111/pce.13860. [PMID: 32716064]
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  • Peter Opio, Hiroyuki Tomiyama, Takanori Saito, Katsuya Ohkawa, Hitoshi Ohara, Satoru Kondo. Paclobutrazol elevates auxin and abscisic acid, reduces gibberellins and zeatin and modulates their transporter genes in Marubakaido apple (Malus prunifolia Borkh. var. ringo Asami) rootstocks. Plant physiology and biochemistry : PPB. 2020 Oct; 155(?):502-511. doi: 10.1016/j.plaphy.2020.08.003. [PMID: 32836196]
  • Iris Eisermann, Václav Motyka, Stefanie Kümmel, Petre I Dobrev, Konstantin Hübner, Holger B Deising, Stefan G R Wirsel. CgIPT1 is required for synthesis of cis-zeatin cytokinins and contributes to stress tolerance and virulence in Colletotrichum graminicola. Fungal genetics and biology : FG & B. 2020 10; 143(?):103436. doi: 10.1016/j.fgb.2020.103436. [PMID: 32693088]
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  • H Tucker Hallmark, Martin Černý, Břetislav Brzobohatý, Aaron M Rashotte. trans-Zeatin-N-glucosides have biological activity in Arabidopsis thaliana. PloS one. 2020; 15(5):e0232762. doi: 10.1371/journal.pone.0232762. [PMID: 32379789]
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