Lincomycin (BioDeep_00000397484)

Main id: BioDeep_00000001802

 


代谢物信息卡片


Lincomycin

化学式: C18H34N2O6S (406.2137)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(general) 20.91%

分子结构信息

SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O
InChI: InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01F - Macrolides, lincosamides and streptogramins > J01FF - Lincosamides
A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D055231 - Lincosamides
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
C784 - Protein Synthesis Inhibitor > C82922 - Lincosamide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
Origin: Microbe, Glycosides, Pyrrolidines
CONFIDENCE standard compound; INTERNAL_ID 1180
CONFIDENCE standard compound; INTERNAL_ID 4105
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3687

同义名列表

3 个代谢物同义名

Lincomycin; Lincomycin; Lincomycin



数据库引用编号

54 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALB, CAT, GLUL, MEFV, MSRA, RPL22, SPX
Peripheral membrane protein 1 COQ10A
Endoplasmic reticulum membrane 2 OSTC, ZDHHC16
Cytoplasmic vesicle, autophagosome 1 MEFV
Nucleus 4 ALB, GLUL, MEFV, RPL22
autophagosome 1 MEFV
cytosol 7 ALB, CAT, GLUL, LIPE, MEFV, MSRA, RPL22
dendrite 1 ACVRL1
phagocytic vesicle 1 STX8
trans-Golgi network 1 STX8
centrosome 1 ALB
nucleoplasm 2 MEFV, MSRA
Cell membrane 5 ACVRL1, GLUL, LIPE, SLC38A5, TNF
Lipid-anchor 2 GLUL, MSRA
lamellipodium 2 MEFV, STX2
Multi-pass membrane protein 4 OSTC, RHO, SLC38A5, ZDHHC16
cell surface 2 ACVRL1, TNF
glutamatergic synapse 1 RPL22
Golgi apparatus 3 ALB, RHO, ZDHHC16
Golgi membrane 1 RHO
mitochondrial inner membrane 2 ATP5ME, COQ10A
neuronal cell body 2 ACVRL1, TNF
synaptic vesicle 1 STX2
Cytoplasm, cytosol 2 GLUL, LIPE
Cytoplasmic vesicle, secretory vesicle 1 SPX
Presynapse 1 RPL22
endosome 1 STX8
plasma membrane 8 ACVRL1, GLUL, MSRA, RHO, SLC38A5, STX2, STX8, TNF
Membrane 10 ACVRL1, CAT, LIPE, MSRA, OSTC, RHO, SLC38A5, STX2, STX8, ZDHHC16
basolateral plasma membrane 1 STX2
caveola 1 LIPE
extracellular exosome 5 ALB, CAT, GLUL, MSRA, RPL22
endoplasmic reticulum 4 ALB, GLUL, OSTC, STX8
extracellular space 5 ALB, IL6, SPX, STX2, TNF
perinuclear region of cytoplasm 1 STX8
mitochondrion 5 ATP5ME, CAT, COQ10A, GLUL, MSRA
protein-containing complex 3 ALB, CAT, STX2
intracellular membrane-bounded organelle 3 CAT, MSRA, STX2
Single-pass type I membrane protein 1 ACVRL1
Secreted 2 ALB, IL6
extracellular region 5 ALB, CAT, IL6, SPX, TNF
Single-pass membrane protein 1 STX8
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
ciliary membrane 1 RHO
photoreceptor inner segment 1 RHO
photoreceptor outer segment 1 RHO
external side of plasma membrane 1 TNF
actin cytoskeleton 1 MSRA
cytoplasmic vesicle 1 MEFV
midbody 1 MSRA
Early endosome 1 STX8
cell-cell junction 1 RHO
recycling endosome 2 STX8, TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 STX8
presynaptic active zone membrane 1 STX2
Cell projection, lamellipodium 1 MEFV
Mitochondrion inner membrane 1 COQ10A
Matrix side 1 COQ10A
Membrane raft 1 TNF
focal adhesion 2 CAT, RPL22
microtubule 1 MEFV
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Cell projection, ruffle 1 MEFV
Late endosome 1 STX8
ruffle 1 MEFV
ciliary basal body 1 ALB
microtubule associated complex 1 MEFV
phagocytic cup 1 TNF
centriole 1 ALB
Cell projection, cilium, photoreceptor outer segment 1 RHO
Secreted, extracellular space 1 SPX
spindle pole 1 ALB
blood microparticle 1 ALB
sperm midpiece 1 RHO
Endomembrane system 2 STX2, STX8
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Golgi-associated vesicle membrane 1 RHO
cell body 1 GLUL
SNARE complex 2 STX2, STX8
Microsome 1 GLUL
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, IL6
platelet alpha granule lumen 1 ALB
Photoreceptor inner segment membrane 1 RHO
dense core granule 1 SPX
transport vesicle 1 SPX
Single-pass type IV membrane protein 1 STX8
ribonucleoprotein complex 1 RPL22
[Isoform 2]: Nucleus 1 MEFV
[Isoform 1]: Cytoplasm, cytoskeleton 1 MEFV
canonical inflammasome complex 1 MEFV
photoreceptor outer segment membrane 1 RHO
sperm head plasma membrane 1 RHO
cytosolic ribosome 1 RPL22
proton-transporting ATP synthase complex 1 ATP5ME
glial cell projection 1 GLUL
photoreceptor disc membrane 1 RHO
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
ribosome 1 RPL22
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
oligosaccharyltransferase complex 1 OSTC
interleukin-6 receptor complex 1 IL6
cytosolic large ribosomal subunit 1 RPL22
rod photoreceptor outer segment 1 RHO
BMP receptor complex 1 ACVRL1
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Shunfen Zhang, Shanlong Tang, Zhengqun Liu, Huiyuan Lv, Xueying Cai, Ruqing Zhong, Liang Chen, Hongfu Zhang. Baicalin restore intestinal damage after early-life antibiotic therapy: the role of the MAPK signaling pathway. Pharmacological research. 2024 Jun; 204(?):107194. doi: 10.1016/j.phrs.2024.107194. [PMID: 38663526]
  • Chun-Yan Lin, Yixian Ru, Yanchao Jin, Qi Lin, Guang-Rong Zhao. PAS domain containing regulator SLCG_7083 involved in morphological development and glucose utilization in Streptomyces lincolnensis. Microbial cell factories. 2023 Dec; 22(1):257. doi: 10.1186/s12934-023-02263-3. [PMID: 38093313]
  • Yuru Shen, Xingyu Zeng, Mingjian Chen, Yun Du, Jun Cheng, Qingji Xie. Photoelectrochemical aptasensing of lincomycin based on a AgI-carboxylated multiwalled carbon nanotubes-BiOI Z-scheme heterojunction. Analytica chimica acta. 2023 Oct; 1278(?):341753. doi: 10.1016/j.aca.2023.341753. [PMID: 37709479]
  • Yanhui Che, Dayong Fan, Zhiyuan Teng, Tongtong Yao, Zihan Wang, Hongbo Zhang, Guangyu Sun, Huihui Zhang, Wah Soon Chow. Potassium alleviates over-reduction of the photosynthetic electron transport chain and helps to maintain photosynthetic function under salt-stress. Physiologia plantarum. 2023 Jul; 175(4):e13981. doi: 10.1111/ppl.13981. [PMID: 37616008]
  • Jiamin Chen, Jiawei Liang, Chenjing Li, Jihua Dai, Wenning Mai, Yongjun Wei. An enriched ammonia-oxidizing microbiota enables high removal efficiency of ammonia in antibiotic production wastewater. Chemosphere. 2023 Jan; 310(?):136854. doi: 10.1016/j.chemosphere.2022.136854. [PMID: 36243093]
  • V Matamoros, M Escolà Casas, E Pastor, Đ Tadić, N Cañameras, N Carazo, J M Bayona. Effects of tetracycline, sulfonamide, fluoroquinolone, and lincosamide load in pig slurry on lettuce: Agricultural and human health implications. Environmental research. 2022 12; 215(Pt 1):114237. doi: 10.1016/j.envres.2022.114237. [PMID: 36084673]
  • B-G Liu, M Xie, Y-T Gong, Y Dong, G-M Zheng, H Wu, G-Z Hu, M Bai, E-P Xu. Prevalence, resistance phenotypes, and fluoroquinolone resistance genes of Salmonella isolates from raw milk of healthy dairy cows in Henan province, China. European review for medical and pharmacological sciences. 2022 09; 26(18):6837-6844. doi: 10.26355/eurrev_202209_29786. [PMID: 36196732]
  • Stefania Fortunato, Cecilia Lasorella, Luca Tadini, Nicolaj Jeran, Federico Vita, Paolo Pesaresi, Maria Concetta de Pinto. GUN1 involvement in the redox changes occurring during biogenic retrograde signaling. Plant science : an international journal of experimental plant biology. 2022 Jul; 320(?):111265. doi: 10.1016/j.plantsci.2022.111265. [PMID: 35643615]
  • Shunfen Zhang, Ruqing Zhong, Shanlong Tang, Hui Han, Liang Chen, Hongfu Zhang. Baicalin Alleviates Short-Term Lincomycin-Induced Intestinal and Liver Injury and Inflammation in Infant Mice. International journal of molecular sciences. 2022 May; 23(11):. doi: 10.3390/ijms23116072. [PMID: 35682750]
  • Xingyu Luo, Qian Yang, Yueting Lin, Zhijun Tang, Jeffery K Tomberlin, Wen Liu, Yongping Huang. Black soldier fly larvae effectively degrade lincomycin from pharmaceutical industry wastes. Journal of environmental management. 2022 Apr; 307(?):114539. doi: 10.1016/j.jenvman.2022.114539. [PMID: 35085969]
  • Jingxian Li, Mengyu Luo, Can Jin, Penghui Zhang, Hongfen Yang, Ren Cai, Weihong Tan. Plasmon-Enhanced Electrochemiluminescence of PTP-Decorated Eu MOF-Based Pt-Tipped Au Bimetallic Nanorods for the Lincomycin Assay. ACS applied materials & interfaces. 2022 Jan; 14(1):383-389. doi: 10.1021/acsami.1c21528. [PMID: 34978181]
  • Shanlong Tang, Shunfen Zhang, Ruqing Zhong, Dan Su, Bing Xia, Lei Liu, Liang Chen, Hongfu Zhang. Time-course alterations of gut microbiota and short-chain fatty acids after short-term lincomycin exposure in young swine. Applied microbiology and biotechnology. 2021 Nov; 105(21-22):8441-8456. doi: 10.1007/s00253-021-11627-x. [PMID: 34651253]
  • Isaac Osei-Bonsu, Alan M McClain, Berkley J Walker, Thomas D Sharkey, David M Kramer. The roles of photorespiration and alternative electron acceptors in the responses of photosynthesis to elevated temperatures in cowpea. Plant, cell & environment. 2021 07; 44(7):2290-2307. doi: 10.1111/pce.14026. [PMID: 33555066]
  • Yonghong Li, Luping Fu, Xuan Li, Yun Wang, Yongjun Wei, Jinfeng Tang, Hongmin Liu. Novel strains with superior degrading efficiency for lincomycin manufacturing biowaste. Ecotoxicology and environmental safety. 2021 Feb; 209(?):111802. doi: 10.1016/j.ecoenv.2020.111802. [PMID: 33360784]
  • Sandeesha Kodru, Ateeq Ur Rehman, Imre Vass. Chloramphenicol enhances Photosystem II photodamage in intact cells of the cyanobacterium Synechocystis PCC 6803. Photosynthesis research. 2020 Sep; 145(3):227-235. doi: 10.1007/s11120-020-00784-1. [PMID: 32979144]
  • Liu Duan, M Águila Ruiz-Sola, Ana Couso, Nil Veciana, Elena Monte. Red and blue light differentially impact retrograde signalling and photoprotection in rice. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2020 06; 375(1801):20190402. doi: 10.1098/rstb.2019.0402. [PMID: 32362254]
  • Oguz Guvenmez, Hüseyin Keskin, Burak Ay, Suayip Birinci, Muhammed Furkan Kanca. The comparison of the effectiveness of lincocin® and azitro® in the treatment of covid-19-associated pneumonia: A prospective study. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique. 2020 06; 27(S Pt 1):e5-e10. doi: 10.15586/jptcp.v27isp1.684. [PMID: 32543164]
  • Saurabh Pandey, Jayesh Dhanani, Jeffrey Lipman, Jason A Roberts, Steve C Wallis, Suzanne L Parker. Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical chemistry and laboratory medicine. 2020 01; 58(2):274-284. doi: 10.1515/cclm-2019-0780. [PMID: 31714883]
  • Allan J Cessna, Sandra L Kuchta, Marley Waiser, Robert B Brua, Jonathan Bailey. Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands. Journal of environmental quality. 2020 Jan; 49(1):236-245. doi: 10.1002/jeq2.20034. [PMID: 33016366]
  • Duorong Xu, Ravi Dhiman, Adriana Garibay, Hans-Peter Mock, Dario Leister, Tatjana Kleine. Cellulose defects in the Arabidopsis secondary cell wall promote early chloroplast development. The Plant journal : for cell and molecular biology. 2020 01; 101(1):156-170. doi: 10.1111/tpj.14527. [PMID: 31498930]
  • Keri L Colabroy, Alyssa D Horwitz, Victoria R Basciano, Yizhi Fu, Kelly M Travitz, Miranda K Robinson, Brittany A Shimanski, Thomas W Hoffmann. A New Way of Belonging: Active-Site Investigation of L-DOPA Dioxygenase, a VOC Family Enzyme from Lincomycin Biosynthesis. Biochemistry. 2019 12; 58(48):4794-4798. doi: 10.1021/acs.biochem.9b00456. [PMID: 31710815]
  • Cheng-Hua Liu, Ya-Hui Chuang, Hui Li, Stephen A Boyd, Brian J Teppen, Javier M Gonzalez, Cliff T Johnston, Johannes Lehmann, Wei Zhang. Long-term sorption of lincomycin to biochars: The intertwined roles of pore diffusion and dissolved organic carbon. Water research. 2019 Sep; 161(?):108-118. doi: 10.1016/j.watres.2019.06.006. [PMID: 31181446]
  • Wenpeng Zhang, Yue Ren, Ziqing Lin, Zheng Ouyang. High-Precision Quantitation of Biofluid Samples Using Direct Mass Spectrometry Analysis. Analytical chemistry. 2019 06; 91(11):6986-6990. doi: 10.1021/acs.analchem.9b01694. [PMID: 31074609]
  • Chang Sun, Deming Dong, Sinan He, Liwen Zhang, Xun Zhang, Chaoqian Wang, Xiuyi Hua, Zhiyong Guo. Multimedia fate modeling of antibiotic sulfamethoxazole, lincomycin, and florfenicol in a seasonally ice-covered river receiving WWTP effluents. Environmental science and pollution research international. 2019 Jun; 26(17):17351-17361. doi: 10.1007/s11356-019-05121-1. [PMID: 31016586]
  • Shanshan Li, Yuli Qi, Lixue Chen, Di Qu, Zhiman Li, Kun Gao, Jianbo Chen, Yinshi Sun. Effects of Panax ginseng polysaccharides on the gut microbiota in mice with antibiotic-associated diarrhea. International journal of biological macromolecules. 2019 Mar; 124(?):931-937. doi: 10.1016/j.ijbiomac.2018.11.271. [PMID: 30503788]
  • Sylwia M Kacprzak, Nobuyoshi Mochizuki, Belén Naranjo, Duorong Xu, Dario Leister, Tatjana Kleine, Haruko Okamoto, Matthew J Terry. Plastid-to-Nucleus Retrograde Signalling during Chloroplast Biogenesis Does Not Require ABI4. Plant physiology. 2019 01; 179(1):18-23. doi: 10.1104/pp.18.01047. [PMID: 30377235]
  • Xiaobo Zhao, Jianyan Huang, Joanne Chory. genome uncoupled1 Mutants Are Hypersensitive to Norflurazon and Lincomycin. Plant physiology. 2018 11; 178(3):960-964. doi: 10.1104/pp.18.00772. [PMID: 30154176]
  • Min Zhang, You-Sheng Liu, Jian-Liang Zhao, Wang-Rong Liu, Liang-Ying He, Jin-Na Zhang, Jun Chen, Lun-Kai He, Qian-Qian Zhang, Guang-Guo Ying. Occurrence, fate and mass loadings of antibiotics in two swine wastewater treatment systems. The Science of the total environment. 2018 Oct; 639(?):1421-1431. doi: 10.1016/j.scitotenv.2018.05.230. [PMID: 29929305]
  • Prakitchai Chotewutmontri, Alice Barkan. Multilevel effects of light on ribosome dynamics in chloroplasts program genome-wide and psbA-specific changes in translation. PLoS genetics. 2018 08; 14(8):e1007555. doi: 10.1371/journal.pgen.1007555. [PMID: 30080854]
  • Barbara Karpinska, Sarah Owdah Alomrani, Christine H Foyer. Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2017 Sep; 372(1730):. doi: 10.1098/rstb.2016.0392. [PMID: 28808105]
  • Ernesto Llamas, Pablo Pulido, Manuel Rodriguez-Concepcion. Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLoS genetics. 2017 Sep; 13(9):e1007022. doi: 10.1371/journal.pgen.1007022. [PMID: 28937985]
  • Yonglan Tian, Petra Ungerer, Huayong Zhang, Alexander V Ruban. Direct impact of the sustained decline in the photosystem II efficiency upon plant productivity at different developmental stages. Journal of plant physiology. 2017 May; 212(?):45-53. doi: 10.1016/j.jplph.2016.10.017. [PMID: 28260626]
  • Da-Yong Fan, Zi-Piao Ye, Shi-Chang Wang, Wah Soon Chow. Multiple roles of oxygen in the photoinactivation and dynamic repair of Photosystem II in spinach leaves. Photosynthesis research. 2016 Mar; 127(3):307-19. doi: 10.1007/s11120-015-0185-y. [PMID: 26297354]
  • Jo-Chien Liao, Wei-Yu Hsieh, Ching-Chih Tseng, Ming-Hsiun Hsieh. Dysfunctional chloroplasts up-regulate the expression of mitochondrial genes in Arabidopsis seedlings. Photosynthesis research. 2016 Feb; 127(2):151-9. doi: 10.1007/s11120-015-0161-6. [PMID: 26008795]
  • Jie Zhou, Kui Zhu, Fei Xu, Wenjun Wang, Haiyang Jiang, Zhanhui Wang, Shuangyang Ding. Development of a microsphere-based fluorescence immunochromatographic assay for monitoring lincomycin in milk, honey, beef, and swine urine. Journal of agricultural and food chemistry. 2014 Dec; 62(49):12061-6. doi: 10.1021/jf5029416. [PMID: 25290082]
  • Renjie Xu, Ying Peng, Mengyue Wang, Lirong Fan, Xiaobo Li. Effects of broad-spectrum antibiotics on the metabolism and pharmacokinetics of ginsenoside Rb1: a study on rats׳ gut microflora influenced by lincomycin. Journal of ethnopharmacology. 2014 Dec; 158 Pt A(?):338-44. doi: 10.1016/j.jep.2014.10.054. [PMID: 25446586]
  • Milena Marsoni, Fabrizio De Mattia, Massimo Labra, Antonia Bruno, Marcella Bracale, Candida Vannini. Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants. Ecotoxicology and environmental safety. 2014 10; 108(?):52-7. doi: 10.1016/j.ecoenv.2014.05.029. [PMID: 25042244]
  • H Szajewska, M Urbańska, A Chmielewska, Z Weizman, R Shamir. Meta-analysis: Lactobacillus reuteri strain DSM 17938 (and the original strain ATCC 55730) for treating acute gastroenteritis in children. Beneficial microbes. 2014 Sep; 5(3):285-93. doi: 10.3920/bm2013.0056. [PMID: 24463209]
  • Sreedharan Sreeshitha Gouri, Dinakaran Venkatachalam, Vinod Kumar Dumka. Pharmacokinetics of lincomycin following single intravenous administration in buffalo calves. Tropical animal health and production. 2014 Aug; 46(6):1099-102. doi: 10.1007/s11250-014-0595-4. [PMID: 24792222]
  • Yuan-Yuan Hu, Da-Yong Fan, Pasquale Losciale, Wah Soon Chow, Wang-Feng Zhang. Whole-tissue determination of the rate coefficients of photoinactivation and repair of photosystem II in cotton leaf discs based on flash-induced P700 redox kinetics. Photosynthesis research. 2013 Nov; 117(1-3):517-28. doi: 10.1007/s11120-013-9822-5. [PMID: 23589088]
  • Kamelia M Osman, Sherif H Marouf, Nayerah Alatfeehy. Antimicrobial resistance and virulence-associated genes of Salmonella enterica subsp. enterica serotypes Muenster, Florian, Omuna, and Noya strains isolated from clinically diarrheic humans in Egypt. Microbial drug resistance (Larchmont, N.Y.). 2013 Oct; 19(5):370-7. doi: 10.1089/mdr.2012.0151. [PMID: 23621859]
  • Esra Bayram Dilek, Ömer İrfan Küfrevioğlu, Şükrü Beydemir. Impacts of some antibiotics on human serum paraoxonase 1 activity. Journal of enzyme inhibition and medicinal chemistry. 2013 Aug; 28(4):758-64. doi: 10.3109/14756366.2012.681653. [PMID: 22591317]
  • Ching-Chih Tseng, Chih-Jen Lee, Yi-Ting Chung, Tzu-Ying Sung, Ming-Hsiun Hsieh. Differential regulation of Arabidopsis plastid gene expression and RNA editing in non-photosynthetic tissues. Plant molecular biology. 2013 Jul; 82(4-5):375-92. doi: 10.1007/s11103-013-0069-5. [PMID: 23645360]
  • Li-Jun Zhou, Guang-Guo Ying, Shan Liu, Jian-Liang Zhao, Bin Yang, Zhi-Feng Chen, Hua-Jie Lai. Occurrence and fate of eleven classes of antibiotics in two typical wastewater treatment plants in South China. The Science of the total environment. 2013 May; 452-453(?):365-76. doi: 10.1016/j.scitotenv.2013.03.010. [PMID: 23538107]
  • Yong-Yi Chen, Ying Wang, Lung-Jiun Shin, Jing-Fen Wu, Varanavasiappan Shanmugam, Munkhtsetseg Tsednee, Jing-Chi Lo, Chyi-Chuann Chen, Shu-Hsing Wu, Kuo-Chen Yeh. Iron is involved in the maintenance of circadian period length in Arabidopsis. Plant physiology. 2013 Mar; 161(3):1409-20. doi: 10.1104/pp.112.212068. [PMID: 23307650]
  • G A Albarellos, L Montoya, G A A Denamiel, M C Velo, M F Landoni. Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats. Journal of veterinary pharmacology and therapeutics. 2012 Dec; 35(6):534-40. doi: 10.1111/j.1365-2885.2011.01355.x. [PMID: 22132730]
  • Phillip A Davis, Roger P Hangarter. Chloroplast movement provides photoprotection to plants by redistributing PSII damage within leaves. Photosynthesis research. 2012 Sep; 112(3):153-61. doi: 10.1007/s11120-012-9755-4. [PMID: 22695784]
  • Kazunori Miyata, Ko Noguchi, Ichiro Terashima. Cost and benefit of the repair of photodamaged photosystem II in spinach leaves: roles of acclimation to growth light. Photosynthesis research. 2012 Sep; 113(1-3):165-80. doi: 10.1007/s11120-012-9767-0. [PMID: 22797856]
  • Erica Belgio, Matthew P Johnson, Snježana Jurić, Alexander V Ruban. Higher plant photosystem II light-harvesting antenna, not the reaction center, determines the excited-state lifetime-both the maximum and the nonphotochemically quenched. Biophysical journal. 2012 Jun; 102(12):2761-71. doi: 10.1016/j.bpj.2012.05.004. [PMID: 22735526]
  • Michael E Ruckle, Lyle D Burgoon, Lauren A Lawrence, Christopher A Sinkler, Robert M Larkin. Plastids are major regulators of light signaling in Arabidopsis. Plant physiology. 2012 May; 159(1):366-90. doi: 10.1104/pp.112.193599. [PMID: 22383539]
  • C P Rezende, L F Souza, M P Almeida, P G Dias, M H Diniz, J C Garcia. Optimisation and validation of a quantitative and confirmatory method for residues of macrolide antibiotics and lincomycin in kidney by liquid chromatography coupled to mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2012; 29(4):587-95. doi: 10.1080/19440049.2011.652196. [PMID: 22320663]
  • Yufei Hu, Gongke Li, Zhujun Zhang. A flow injection chemiluminescence method for the determination of lincomycin in serum using a diperiodato-cuprate (III)-luminol system. Luminescence : the journal of biological and chemical luminescence. 2011 Sep; 26(5):313-8. doi: 10.1002/bio.1230. [PMID: 22021244]
  • Kim Gabriele Beisel, Ulrich Schurr, Shizue Matsubara. Altered turnover of β-carotene and Chl a in Arabidopsis leaves treated with lincomycin or norflurazon. Plant & cell physiology. 2011 Jul; 52(7):1193-203. doi: 10.1093/pcp/pcr069. [PMID: 21632655]
  • Amanda Cottage, John C Gray. Timing the switch to phototrophic growth: a possible role of GUN1. Plant signaling & behavior. 2011 Apr; 6(4):578-82. doi: 10.4161/psb.6.4.14900. [PMID: 21673514]
  • Y Tao, D Chen, G Yu, H Yu, Y Pan, Y Wang, L Huang, Z Yuan. Simultaneous determination of lincomycin and spectinomycin residues in animal tissues by gas chromatography-nitrogen phosphorus detection and gas chromatography-mass spectrometry with accelerated solvent extraction. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2011 Feb; 28(2):145-54. doi: 10.1080/19440049.2010.538440. [PMID: 21240824]
  • Marja Hakala-Yatkin, Mika Mäntysaari, Heta Mattila, Esa Tyystjärvi. Contributions of visible and ultraviolet parts of sunlight to photoinhibition. Plant & cell physiology. 2010 Oct; 51(10):1745-53. doi: 10.1093/pcp/pcq133. [PMID: 20798275]
  • Päivi Sarvikas, Marja Hakala-Yatkin, Sirin Dönmez, Esa Tyystjärvi. Short flashes and continuous light have similar photoinhibitory efficiency in intact leaves. Journal of experimental botany. 2010 Oct; 61(15):4239-47. doi: 10.1093/jxb/erq224. [PMID: 20643811]
  • Martha Sainz, Pedro Díaz, Jorge Monza, Omar Borsani. Heat stress results in loss of chloroplast Cu/Zn superoxide dismutase and increased damage to Photosystem II in combined drought-heat stressed Lotus japonicus. Physiologia plantarum. 2010 Sep; 140(1):46-56. doi: 10.1111/j.1399-3054.2010.01383.x. [PMID: 20487374]
  • Amanda Cottage, Ellie K Mott, Jennie A Kempster, John C Gray. The Arabidopsis plastid-signalling mutant gun1 (genomes uncoupled1) shows altered sensitivity to sucrose and abscisic acid and alterations in early seedling development. Journal of experimental botany. 2010 Aug; 61(13):3773-86. doi: 10.1093/jxb/erq186. [PMID: 20605896]
  • Neelam Keswani, Sinjan Choudhary, Nand Kishore. Interaction of weakly bound antibiotics neomycin and lincomycin with bovine and human serum albumin: biophysical approach. Journal of biochemistry. 2010 Jul; 148(1):71-84. doi: 10.1093/jb/mvq035. [PMID: 20356824]
  • Alex Avdeef, Kin Y Tam. How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?. Journal of medicinal chemistry. 2010 May; 53(9):3566-84. doi: 10.1021/jm901846t. [PMID: 20373811]
  • Mueen Aslam, Moussa S Diarra, Cara Service, Heidi Rempel. Characterization of antimicrobial resistance in Enterococcus spp. recovered from a commercial beef processing plant. Foodborne pathogens and disease. 2010 Mar; 7(3):235-41. doi: 10.1089/fpd.2009.0380. [PMID: 19911933]
  • Päivi Sarvikas, Taina Tyystjärvi, Esa Tyystjärvi. Kinetics of prolonged photoinhibition revisited: photoinhibited Photosystem II centres do not protect the active ones against loss of oxygen evolution. Photosynthesis research. 2010 Jan; 103(1):7-17. doi: 10.1007/s11120-009-9496-1. [PMID: 19760110]
  • Yusuke Kato, Eiko Miura, Kunio Ido, Kentaro Ifuku, Wataru Sakamoto. The variegated mutants lacking chloroplastic FtsHs are defective in D1 degradation and accumulate reactive oxygen species. Plant physiology. 2009 Dec; 151(4):1790-801. doi: 10.1104/pp.109.146589. [PMID: 19767385]
  • Xiaofan Sui, Jin Sun, Haiyan Li, Yongjun Wang, Jianfang Liu, Xiaohong Liu, Wenping Zhang, Lijiang Chen, Zhonggui He. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry. 2009 Nov; 44(11):4455-60. doi: 10.1016/j.ejmech.2009.06.004. [PMID: 19586686]
  • Berenika Pokorska, Maksymilian Zienkiewicz, Marta Powikrowska, Anna Drozak, Elzbieta Romanowska. Differential turnover of the photosystem II reaction centre D1 protein in mesophyll and bundle sheath chloroplasts of maize. Biochimica et biophysica acta. 2009 Oct; 1787(10):1161-9. doi: 10.1016/j.bbabio.2009.05.002. [PMID: 19450540]
  • Sandra L Kuchta, Allan J Cessna. Fate of lincomycin in snowmelt runoff from manure-amended pasture. Chemosphere. 2009 Jul; 76(4):439-46. doi: 10.1016/j.chemosphere.2009.03.069. [PMID: 19419747]
  • Sandra L Kuchta, Allan J Cessna. Lincomycin and spectinomycin concentrations in liquid swine manure and their persistence during simulated manure storage. Archives of environmental contamination and toxicology. 2009 Jul; 57(1):1-10. doi: 10.1007/s00244-008-9229-z. [PMID: 18800201]
  • Sandra L Kuchta, Allan J Cessna, Jane A Elliott, Kerry M Peru, John V Headley. Transport of lincomycin to surface and ground water from manure-amended cropland. Journal of environmental quality. 2009 Jul; 38(4):1719-27. doi: 10.2134/jeq2008.0365. [PMID: 19549949]
  • Mei-Hsin Chiu, Hsueh-Hui Yang, Chi-Ho Liu, Jyh-Myng Zen. Determination of lincomycin in urine and some foodstuffs by flow injection analysis coupled with liquid chromatography and electrochemical detection with a preanodized screen-printed carbon electrode. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Apr; 877(10):991-4. doi: 10.1016/j.jchromb.2009.02.066. [PMID: 19285928]
  • Françoise Banères-Roquet, Maxime Gualtieri, Philippe Villain-Guillot, Martine Pugnière, Jean-Paul Leonetti. Use of a surface plasmon resonance method to investigate antibiotic and plasma protein interactions. Antimicrobial agents and chemotherapy. 2009 Apr; 53(4):1528-31. doi: 10.1128/aac.00971-08. [PMID: 19164148]
  • Takaaki Ando, Hiroki Fujiwara, Masayuki Kohiruimaki, Tomohito Hayashi, Hiromichi Ohtsuka, Daisaku Watanabe, Masaaki Oikawa, Masateru Koiwa. Peripheral blood leukocyte subpopulation of dairy cows with digital dermatitis and effect of hoof trimming with antibiotic treatment. The Journal of veterinary medical science. 2009 Apr; 71(4):391-5. doi: 10.1292/jvms.71.391. [PMID: 19420839]
  • Jing-zhe Zhang, Xue-lin Zhang, Xiao-qiang Liang, Hong-gang Gu, Pei-ting Zhu. [Effects of different Chinese herbal medicines on biochemical parameters in guinea-pig with pigment gallstones]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. 2008 Aug; 6(8):856-9. doi: 10.3736/jcim20080816. [PMID: 18664357]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • S Akhter, M S Ansari, Smh Andrabi, N Ullah, M Qayyum. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. Reproduction in domestic animals = Zuchthygiene. 2008 Jun; 43(3):272-278. doi: 10.1111/j.1439-0531.2007.00890.x. [PMID: 18042206]
  • M Mutinati, M Spedicato, R Manca, C Trisolini, G Minoia, A Rizzo, R L Sciorsci. Influence of antibiotic therapy on serum levels of reactive oxygen species in ovariectomized bitches. Journal of veterinary pharmacology and therapeutics. 2008 Feb; 31(1):18-21. doi: 10.1111/j.1365-2885.2007.00919.x. [PMID: 18177314]
  • Sachiko Nameda, Noriko N Miura, Yoshiyuki Adachi, Naohito Ohno. Lincomycin protects mice from septic shock in beta-glucan-indomethacin model. Biological & pharmaceutical bulletin. 2007 Dec; 30(12):2312-6. doi: 10.1248/bpb.30.2312. [PMID: 18057718]
  • Khaled Al-Taweel, Toshio Iwaki, Yukinori Yabuta, Shigeru Shigeoka, Norio Murata, Akira Wadano. A bacterial transgene for catalase protects translation of d1 protein during exposure of salt-stressed tobacco leaves to strong light. Plant physiology. 2007 Sep; 145(1):258-65. doi: 10.1104/pp.107.101733. [PMID: 17660354]
  • Josef Komenda, Martin Tichy, Ondrej Prásil, Jana Knoppová, Stanislava Kuviková, Remco de Vries, Peter J Nixon. The exposed N-terminal tail of the D1 subunit is required for rapid D1 degradation during photosystem II repair in Synechocystis sp PCC 6803. The Plant cell. 2007 Sep; 19(9):2839-54. doi: 10.1105/tpc.107.053868. [PMID: 17905897]
  • Eva Hideg, Péter B Kós, Imre Vass. Photosystem II damage induced by chemically generated singlet oxygen in tobacco leaves. Physiologia plantarum. 2007 Sep; 131(1):33-40. doi: 10.1111/j.1399-3054.2007.00913.x. [PMID: 18251922]
  • Shai Koussevitzky, Ajit Nott, Todd C Mockler, Fangxin Hong, Gilberto Sachetto-Martins, Marci Surpin, Jason Lim, Ron Mittler, Joanne Chory. Signals from chloroplasts converge to regulate nuclear gene expression. Science (New York, N.Y.). 2007 May; 316(5825):715-9. doi: 10.1126/science. 1140516. [PMID: 17395793]
  • C Alexopoulos, P D Tassis, C S Kyriakis, E D Tzika, V Papatsiros, S C Kyriakis. First experience on the effect of in-feed lincomycin for the control of proliferative enteropathy in growing pigs. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. 2006 Apr; 53(3):157-62. doi: 10.1111/j.1439-0442.2006.00803.x. [PMID: 16533333]
  • László Gáspár, Eva Sárvári, Fermín Morales, Zoltán Szigeti. Presence of 'PSI free' LHCI and monomeric LHCII and subsequent effects on fluorescence characteristics in lincomycin treated maize. Planta. 2006 Apr; 223(5):1047-57. doi: 10.1007/s00425-005-0149-0. [PMID: 16292567]
  • E V Dzyubinskaya, D B Kiselevsky, L E Bakeeva, V D Samuilov. Programmed cell death in plants: effect of protein synthesis inhibitors and structural changes in pea guard cells. Biochemistry. Biokhimiia. 2006 Apr; 71(4):395-405. doi: 10.1134/s0006297906040079. [PMID: 16615859]
  • Kerry M Peru, Sandra L Kuchta, John V Headley, Allan J Cessna. Development of a hydrophilic interaction chromatography-mass spectrometry assay for spectinomycin and lincomycin in liquid hog manure supernatant and run-off from cropland. Journal of chromatography. A. 2006 Feb; 1107(1-2):152-8. doi: 10.1016/j.chroma.2005.12.057. [PMID: 16412452]
  • Roberto Andreozzi, Marisa Canterino, Roberto Lo Giudice, Raffaele Marotta, Gabriele Pinto, Antonino Pollio. Lincomycin solar photodegradation, algal toxicity and removal from wastewaters by means of ozonation. Water research. 2006 Feb; 40(3):630-8. doi: 10.1016/j.watres.2005.11.023. [PMID: 16405942]
  • Alessandra Carucci, Giovanna Cappai, Martina Piredda. Biodegradability and toxicity of pharmaceuticals in biological wastewater treatment plants. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2006; 41(9):1831-42. doi: 10.1080/10934520600779000. [PMID: 16849129]
  • Christian Dubos, Janet Willment, David Huggins, Guy H Grant, Malcolm M Campbell. Kanamycin reveals the role played by glutamate receptors in shaping plant resource allocation. The Plant journal : for cell and molecular biology. 2005 Aug; 43(3):348-55. doi: 10.1111/j.1365-313x.2005.02458.x. [PMID: 16045471]
  • Zhi-Ru Tang, Yu-Long Yin, Charles M Nyachoti, Rui-Lin Huang, Tie-Jun Li, Chengbo Yang, Xiao-Jian Yang, Joshua Gong, Jiang Peng, De-Sheng Qi, Jian-Jun Xing, Zhi-Hong Sun, Ming Z Fan. Effect of dietary supplementation of chitosan and galacto-mannan-oligosaccharide on serum parameters and the insulin-like growth factor-I mRNA expression in early-weaned piglets. Domestic animal endocrinology. 2005 May; 28(4):430-41. doi: 10.1016/j.domaniend.2005.02.003. [PMID: 15826777]
  • A D Al-Ebous, B Hiasat, M Sarayrah, M Al-Jahmi, A N Al-Zuriqat. Management of diabetic foot in a Jordanian hospital. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit. 2005 May; 11(3):490-3. doi: NULL. [PMID: 16602471]
  • Alex C McCormac, Matthew J Terry. The nuclear genes Lhcb and HEMA1 are differentially sensitive to plastid signals and suggest distinct roles for the GUN1 and GUN5 plastid-signalling pathways during de-etiolation. The Plant journal : for cell and molecular biology. 2004 Dec; 40(5):672-85. doi: 10.1111/j.1365-313x.2004.02243.x. [PMID: 15546351]
  • Xiaocui Zhao, Tianyan You, Haibo Qiu, Jilin Yan, Xiurong Yang, Erkang Wang. Electrochemiluminescence detection with integrated indium tin oxide electrode on electrophoretic microchip for direct bioanalysis of lincomycin in the urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Oct; 810(1):137-42. doi: 10.1016/j.jchromb.2004.07.018. [PMID: 15358317]
  • K ABO EL-SOOUD, A Goudah, A M Abd El-Aty. Lack of pharmacokinetic interaction between lincomycin and aspirin in healthy goats. Journal of veterinary pharmacology and therapeutics. 2004 Oct; 27(5):389-92. doi: 10.1111/j.1365-2885.2004.00611.x. [PMID: 15500581]
  • Pekka Suomalainen, Christoffer Johans, Tim Söderlund, Paavo K J Kinnunen. Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry. 2004 Mar; 47(7):1783-8. doi: 10.1021/jm0309001. [PMID: 15027870]
  • Sadettin Tanyildizi, Tanzer Bozkurt. The effects of lincomycin-spectinomycin and sulfamethoxazole-trimethoprim on hyaluronidase activities and sperm characteristics of rams. The Journal of veterinary medical science. 2003 Jul; 65(7):775-80. doi: 10.1292/jvms.65.775. [PMID: 12939503]
  • Elena Bergo, Anna Segalla, Giorgio Mario Giacometti, Delia Tarantino, Carlo Soave, Flora Andreucci, Roberto Barbato. Role of visible light in the recovery of photosystem II structure and function from ultraviolet-B stress in higher plants. Journal of experimental botany. 2003 Jul; 54(388):1665-73. doi: 10.1093/jxb/erg180. [PMID: 12754266]
  • James A Sullivan, John C Gray. Multiple plastid signals regulate the expression of the pea plastocyanin gene in pea and transgenic tobacco plants. The Plant journal : for cell and molecular biology. 2002 Dec; 32(5):763-74. doi: 10.1046/j.1365-313x.2002.01464.x. [PMID: 12472691]
  • Marc Cherlet, Siska Croubels, Patrick De Backer. Determination of clindamycin in animal plasma by high-performance liquid chromatography combined with electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS. 2002 Aug; 37(8):848-53. doi: 10.1002/jms.344. [PMID: 12203678]
  • Eija Pätsikkä, Marja Kairavuo, Frantisek Sersen, Eva-Mari Aro, Esa Tyystjärvi. Excess copper predisposes photosystem II to photoinhibition in vivo by outcompeting iron and causing decrease in leaf chlorophyll. Plant physiology. 2002 Jul; 129(3):1359-67. doi: 10.1104/pp.004788. [PMID: 12114589]