1-Hydroxyisoquinoline (BioDeep_00000003967)

 

Secondary id: BioDeep_00001868896

human metabolite blood metabolite


代谢物信息卡片


1,2-dihydroisoquinolin-1-one

化学式: C9H7NO (145.0527612)
中文名称: 2H-异喹啉-1-酮, 异喹诺酮
谱图信息: 最多检出来源 Homo sapiens(blood) 0.17%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=CNC2=O
InChI: InChI=1S/C9H7NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-6H,(H,10,11)

描述信息

CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 70
COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

6 个代谢物同义名

1,2-dihydroisoquinolin-1-one; ISOQUINOLIN-1(2H)-ONE; 1-Hydroxyisoquinoline; 1(2H)-Isoquinolinone; Isocarbostyril; Isoquinolone



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Subhash C Joshi, Chandra S Mathela. Antioxidant and antibacterial activities of the leaf essential oil and its constituents furanodienone and curzerenone from Lindera pulcherrima (Nees.) Benth. ex hook. f. Pharmacognosy research. 2012 Apr; 4(2):80-4. doi: 10.4103/0974-8490.94721. [PMID: 22518079]
  • Andrew J McKenzie, Shirley L Campbell, Alan K Howe. Protein kinase A activity and anchoring are required for ovarian cancer cell migration and invasion. PloS one. 2011; 6(10):e26552. doi: 10.1371/journal.pone.0026552. [PMID: 22028904]
  • Ai Hua Zhang, Nan Jiang, Wen Gu, Jing Ma, Yu Rong Wang, Yong Chun Song, Ren Xiang Tan. Characterization, synthesis and self-aggregation of (-)-alternarlactam: a new fungal cytotoxin with cyclopentenone and isoquinolinone scaffolds. Chemistry (Weinheim an der Bergstrasse, Germany). 2010 Dec; 16(48):14479-85. doi: 10.1002/chem.201002205. [PMID: 21038331]
  • Chanhui Lee, Quincy Teng, Wenlin Huang, Ruiqin Zhong, Zheng-Hua Ye. The Arabidopsis family GT43 glycosyltransferases form two functionally nonredundant groups essential for the elongation of glucuronoxylan backbone. Plant physiology. 2010 Jun; 153(2):526-41. doi: 10.1104/pp.110.155309. [PMID: 20335400]
  • El-Hadi M Ahmed, Bakri Y M Nour, Yousif G Mohammed, Hassan S Khalid. Antiplasmodial Activity of Some Medicinal Plants Used in Sudanese Folk-medicine. Environmental health insights. 2010 02; 4(?):1-6. doi: 10.4137/ehi.s4108. [PMID: 20523878]
  • Axel Teichert, Jürgen Schmidt, Andrea Porzel, Norbert Arnold, Ludger Wessjohann. (Iso)-quinoline alkaloids from fungal fruiting bodies of Cortinarius subtortus. Journal of natural products. 2008 Jun; 71(6):1092-4. doi: 10.1021/np8000859. [PMID: 18447384]
  • Christopher P Regan, Laszlo Kiss, Gary L Stump, Charles J McIntyre, Douglas C Beshore, Nigel J Liverton, Christopher J Dinsmore, Joseph J Lynch. Atrial antifibrillatory effects of structurally distinct IKur blockers 3-[(dimethylamino)methyl]-6-methoxy-2-methyl-4-phenylisoquinolin-1(2H)-one and 2-phenyl-1,1-dipyridin-3-yl-2-pyrrolidin-1-yl-ethanol in dogs with underlying heart failure. The Journal of pharmacology and experimental therapeutics. 2008 Jan; 324(1):322-30. doi: 10.1124/jpet.107.127654. [PMID: 17967939]
  • Virginia M Zaleskas, Daniela S Krause, Katherine Lazarides, Nihal Patel, Yiguo Hu, Shaoguang Li, Richard A Van Etten. Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F. PloS one. 2006 Dec; 1(?):e18. doi: 10.1371/journal.pone.0000018. [PMID: 17183644]
  • Chen Xie, Nigel C Veitch, Peter J Houghton, Monique S J Simmonds. Flavonoid glycosides and isoquinolinone alkaloids from Corydalis bungeana. Phytochemistry. 2004 Nov; 65(22):3041-7. doi: 10.1016/j.phytochem.2004.09.009. [PMID: 15504439]