Resorcine (BioDeep_00000395744)

Main id: BioDeep_00000002919

 

PANOMIX_OTCML-2023


代谢物信息卡片


Resorcinol

化学式: C6H6O2 (110.0368)
中文名称: 间苯二酚标准溶液, 间苯二酚, 雷琐辛, 雷琐酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC(=C1)O)O
InChI: InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

描述信息

D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent

同义名列表

4 个代谢物同义名

Resorcinol; Resorcine; Resorcinol; Resorcinol



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(5)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ALB, BCL2, CASP3, CAT, CNR2, ELANE, ERBB2, HSP90AA2P, MITF, MSMP, PTGS2, TYR
Peripheral membrane protein 3 ACHE, CYP1B1, PTGS2
Endosome membrane 1 ERBB2
Endoplasmic reticulum membrane 4 BCL2, CYP1B1, HSP90B1, PTGS2
Nucleus 8 ACHE, ALB, BCL2, CASP3, CD274, ERBB2, HSP90B1, MITF
cytosol 9 ALB, BCL2, CASP3, CAT, ELANE, ERBB2, HSP90AA2P, HSP90B1, MITF
dendrite 1 CNR2
phagocytic vesicle 1 ELANE
centrosome 1 ALB
nucleoplasm 4 CASP3, CD274, ERBB2, MITF
Cell membrane 4 ACHE, CD274, ERBB2, PDCD1
ruffle membrane 1 ERBB2
Early endosome membrane 1 CD274
Synapse 1 ACHE
cell surface 3 ACHE, ELANE, TPO
glutamatergic synapse 1 CASP3
Golgi apparatus 2 ACHE, ALB
Golgi membrane 1 INS
lysosomal membrane 1 MITF
neuromuscular junction 2 ACHE, ERBB2
neuronal cell body 1 CASP3
presynaptic membrane 1 ERBB2
smooth endoplasmic reticulum 1 HSP90B1
Lysosome 1 TYR
plasma membrane 7 ACHE, CD274, CNR2, ERBB2, HSP90AA2P, PDCD1, TPO
Membrane 8 ACHE, BCL2, CAT, CYP1B1, ERBB2, HSP90B1, PDCD1, TPO
apical plasma membrane 1 ERBB2
basolateral plasma membrane 1 ERBB2
caveola 1 PTGS2
extracellular exosome 6 ALB, CAT, CD274, ELANE, HSP90AA2P, HSP90B1
Lysosome membrane 1 MITF
endoplasmic reticulum 5 ALB, BCL2, CNR2, HSP90B1, PTGS2
extracellular space 6 ACHE, ALB, ELANE, INS, MSMP, TPO
perinuclear region of cytoplasm 5 ACHE, ERBB2, HSP90AA2P, HSP90B1, TYR
mitochondrion 3 BCL2, CAT, CYP1B1
protein-containing complex 7 ALB, BCL2, CAT, HSP90AA2P, HSP90B1, MITF, PTGS2
intracellular membrane-bounded organelle 3 CAT, CYP1B1, TYR
Microsome membrane 2 CYP1B1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 4 CD274, ERBB2, TPO, TYR
Secreted 4 ACHE, ALB, INS, MSMP
extracellular region 8 ACHE, ALB, CAT, ELANE, ELN, ERBB2, HSP90B1, INS
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
anchoring junction 1 ALB
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 CD274, PDCD1
Secreted, extracellular space, extracellular matrix 1 ELN
actin cytoskeleton 1 CD274
perikaryon 1 CNR2
cytoplasmic vesicle 1 ERBB2
Melanosome membrane 1 TYR
midbody 1 HSP90B1
Early endosome 1 ERBB2
Golgi-associated vesicle 1 TYR
postsynaptic membrane 1 CNR2
Cell projection, ruffle membrane 1 ERBB2
Cytoplasm, perinuclear region 1 ERBB2
pore complex 1 BCL2
focal adhesion 2 CAT, HSP90B1
extracellular matrix 1 ELN
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 3 ELANE, ELN, HSP90B1
secretory granule 1 ELANE
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 ERBB2
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 MITF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Lipid-anchor, GPI-anchor 1 ACHE
Recycling endosome membrane 1 CD274
endosome lumen 1 INS
Cell projection, dendrite 1 CNR2
Melanosome 2 HSP90B1, TYR
side of membrane 1 ACHE
myelin sheath 2 BCL2, ERBB2
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 ERBB2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, HSP90B1, INS, PTGS2
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 ALB
specific granule lumen 1 ELANE
transport vesicle 1 INS
azurophil granule lumen 1 ELANE
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
semaphorin receptor complex 1 ERBB2
Sarcoplasmic reticulum lumen 1 HSP90B1
extrinsic component of cytoplasmic side of plasma membrane 1 CNR2
synaptic cleft 1 ACHE
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 2 CD274, ERBB2
[Isoform 4]: Secreted 1 CD274
Cytoplasmic vesicle, phagosome 1 ELANE
elastic fiber 1 ELN
endocytic vesicle lumen 1 HSP90B1
catalase complex 1 CAT
ERBB3:ERBB2 complex 1 ERBB2
endoplasmic reticulum chaperone complex 1 HSP90B1
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
[Isoform 2]: Endomembrane system 1 CD274


文献列表

  • Eva Arrebola, Francesca R Aprile, Claudia E Calderón, Antonio de Vicente, Francisco M Cazorla. Insecticidal features displayed by the beneficial rhizobacterium Pseudomonas chlororaphis PCL1606. International microbiology : the official journal of the Spanish Society for Microbiology. 2022 Nov; 25(4):679-689. doi: 10.1007/s10123-022-00253-w. [PMID: 35670867]
  • Anna Jeżewska, Dorota Kondej. [Resorcinol - determination method in the workplace air]. Medycyna pracy. 2022 Apr; 73(2):135-142. doi: 10.13075/mp.5893.01150. [PMID: 35373783]
  • Andrew S Elder, John N Coupland, Ryan J Elias. Effect of alkyl chain length on the antioxidant activity of alkylresorcinol homologues in bulk oils and oil-in-water emulsions. Food chemistry. 2021 Jun; 346(?):128885. doi: 10.1016/j.foodchem.2020.128885. [PMID: 33429298]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Stanislas Nsanzamahoro, Ying Zhang, Wei-Feng Wang, Yu-Zhu Ding, Yan-Ping Shi, Jun-Li Yang. Fluorescence 'turn-on' of silicon-containing nanoparticles for the determination of resorcinol. Mikrochimica acta. 2021 01; 188(2):46. doi: 10.1007/s00604-021-04700-9. [PMID: 33483779]
  • Miroslav Sisa, Marcela Dvorakova, Veronika Temml, Veronika Jarosova, Tomas Vanek, Premysl Landa. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. European journal of medicinal chemistry. 2020 Oct; 204(?):112620. doi: 10.1016/j.ejmech.2020.112620. [PMID: 32738413]
  • Yulin Sun, Ruonan Yao, Xiufeng Ji, Hongqi Wu, Alvaro Luna, Zhonghua Wang, Reinhard Jetter. Characterization of an alkylresorcinol synthase that forms phenolics accumulating in the cuticular wax on various organs of rye (Secale cereale). The Plant journal : for cell and molecular biology. 2020 06; 102(6):1294-1312. doi: 10.1111/tpj.14704. [PMID: 31981252]
  • Cheirmadurai Kalirajan, Thanikaivelan Palanisamy. Silica microsphere-resorcinol composite embedded collagen scaffolds impart scar-less healing of chronic infected burns in type-I diabetic and non-diabetic rats. Biomaterials science. 2020 Mar; 8(6):1622-1637. doi: 10.1039/c9bm01089k. [PMID: 31967622]
  • Md Shahinozzaman, Takahiro Ishii, Mohammad A Halim, Md Amzad Hossain, Md Tofazzal Islam, Shinkichi Tawata. Cytotoxic and anti-inflammatory resorcinol and alkylbenzoquinone derivatives from the leaves of Ardisia sieboldii. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2019 Nov; 74(11-12):303-311. doi: 10.1515/znc-2019-0114. [PMID: 31437126]
  • Yantao Zhao, Lei Shi, Changling Hu, Shengmin Sang. Wheat Bran for Colon Cancer Prevention: The Synergy between Phytochemical Alkylresorcinol C21 and Intestinal Microbial Metabolite Butyrate. Journal of agricultural and food chemistry. 2019 Nov; 67(46):12761-12769. doi: 10.1021/acs.jafc.9b05666. [PMID: 31675233]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • Jie Tu, Guanhui Liu, Xitao Cao, Shuyun Zhu, Qiang Li, Gengsheng Ji, Yanhui Han, Hang Xiao. Hypoglycemic effects of wheat bran alkyresorcinols in high-fat/high-sucrose diet and low-dose streptozotocin-induced type 2 diabetic male mice and protection of pancreatic β cells. Food & function. 2019 Jun; 10(6):3282-3290. doi: 10.1039/c8fo02396d. [PMID: 31094396]
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  • George Harrison Ferreira de Carvalho, Milene Aparecida de Andrade, Carla Nunes de Araújo, Maria Lucília Santos, Natália Alves de Castro, Sébastien Charneau, Rose Monnerat, Jaime Martins de Santana, Izabela Marques Dourado Bastos. Larvicidal and pupicidal activities of eco-friendly phenolic lipid products from Anacardium occidentale nutshell against arbovirus vectors. Environmental science and pollution research international. 2019 Feb; 26(6):5514-5523. doi: 10.1007/s11356-018-3905-y. [PMID: 30610586]
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  • Simo P Porras, Minna Hartonen, Katriina Ylinen, Jarkko Tornaeus, Tapani Tuomi, Tiina Santonen. Environmental and occupational exposure to resorcinol in Finland. Toxicology letters. 2018 Dec; 298(?):125-133. doi: 10.1016/j.toxlet.2018.03.027. [PMID: 29596886]
  • Marcela Dvorakova, Adela Hylova, Petr Soudek, Katarzyna Retzer, Lukas Spichal, Tomas Vanek. Resorcinol-Type Strigolactone Mimics as Potent Germinators of the Parasitic Plants Striga hermonthica and Phelipanche ramosa. Journal of natural products. 2018 11; 81(11):2321-2328. doi: 10.1021/acs.jnatprod.8b00160. [PMID: 30362743]
  • Huiwen Yan, Lei Sun, Jinge Huang, Yixing Qiu, Fuchao Xu, Riming Yan, Du Zhu, Wei Wang, Jixun Zhan. Identification and heterologous reconstitution of a 5-alk(en)ylresorcinol synthase from endophytic fungus Shiraia sp. Slf14. Journal of microbiology (Seoul, Korea). 2018 Nov; 56(11):805-812. doi: 10.1007/s12275-018-8278-x. [PMID: 30353466]
  • Kang Liang, Fengqiong Shi, Jingfu Liu. Occurrence and distribution of oligomeric organophosphorus flame retardants in different treatment stages of a sewage treatment plant. Environmental pollution (Barking, Essex : 1987). 2018 Jan; 232(?):229-235. doi: 10.1016/j.envpol.2017.09.036. [PMID: 28941720]
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  • Janna Frombach, Anna Sonnenburg, Björn-Dirk Krapohl, Torsten Zuberbier, Ralf Stahlmann, Maximilian Schreiner. A novel method to generate monocyte-derived dendritic cells during coculture with HaCaT facilitates detection of weak contact allergens in cosmetics. Archives of toxicology. 2017 Jan; 91(1):339-350. doi: 10.1007/s00204-016-1722-y. [PMID: 27136899]
  • Yu-Meng Gao, Tian-Yu Sun, Min Ma, Guo-Dong Chen, Zheng-Qun Zhou, Chuan-Xi Wang, Dan Hu, Li-Guo Chen, Xin-Sheng Yao, Hao Gao. Adeninealkylresorcinol, the first alkylresorcinol tethered with nucleobase from Lasiodiplodia sp. Fitoterapia. 2016 Jul; 112(?):254-9. doi: 10.1016/j.fitote.2016.06.011. [PMID: 27343368]
  • Md Iqbal Alam, Mohammed A Alam, Ozair Alam, Amit Nargotra, Subhash Chandra Taneja, Surrinder Koul. Molecular modeling and snake venom phospholipase A2 inhibition by phenolic compounds: Structure-activity relationship. European journal of medicinal chemistry. 2016 May; 114(?):209-19. doi: 10.1016/j.ejmech.2016.03.008. [PMID: 26986086]
  • Jeremy A Leonard, Yu-Mei Tan, Mary Gilbert, Kristin Isaacs, Hisham El-Masri. Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling. Toxicological sciences : an official journal of the Society of Toxicology. 2016 05; 151(1):57-70. doi: 10.1093/toxsci/kfw022. [PMID: 26865668]
  • Ângelo Luís, Fernanda Domingues, Ana Paula Duarte. Biological Properties of Plant-Derived Alkylresorcinols: Mini-Review. Mini reviews in medicinal chemistry. 2016; 16(11):851-4. doi: 10.2174/1389557516666160211121437. [PMID: 26864549]
  • Christian Molitor, Stephan Gerhard Mauracher, Annette Rompel. Crystallization and preliminary crystallographic analysis of latent, active and recombinantly expressed aurone synthase, a polyphenol oxidase, from Coreopsis grandiflora. Acta crystallographica. Section F, Structural biology communications. 2015 Jun; 71(Pt 6):746-51. doi: 10.1107/s2053230x15007542. [PMID: 26057806]
  • Ritu Chaudhary, Hagop S Atamian, Zhouxin Shen, Steven P Briggs, Isgouhi Kaloshian. Potato aphid salivary proteome: enhanced salivation using resorcinol and identification of aphid phosphoproteins. Journal of proteome research. 2015 Apr; 14(4):1762-78. doi: 10.1021/pr501128k. [PMID: 25722084]
  • Claudia E Calderón, Cayo Ramos, Antonio de Vicente, Francisco M Cazorla. Comparative Genomic Analysis of Pseudomonas chlororaphis PCL1606 Reveals New Insight into Antifungal Compounds Involved in Biocontrol. Molecular plant-microbe interactions : MPMI. 2015 Mar; 28(3):249-60. doi: 10.1094/mpmi-10-14-0326-fi. [PMID: 25679537]
  • Alastair B Ross, Marjorelee T Colega, Ai Lin Lim, Irma Silva-Zolezzi, Katherine Macé, Seang Mei Saw, Kenneth Kwek, Peter Gluckman, Keith M Godfrey, Yap-Seng Chong, Mary F F Chong. Whole grain intake, determined by dietary records and plasma alkylresorcinol concentrations, is low among pregnant women in Singapore. Asia Pacific journal of clinical nutrition. 2015; 24(4):674-82. doi: 10.6133/apjcn.2015.24.4.19. [PMID: 26693753]
  • Francisco J Hidalgo, Rosario Zamora. 2-Alkenal-scavenging ability of m-diphenols. Food chemistry. 2014 Oct; 160(?):118-26. doi: 10.1016/j.foodchem.2014.03.071. [PMID: 24799217]
  • Hoskote Anand Kiran Kumar, Badal Kumar Mandal, Kesarla Mohan Kumar, Sireesh babu Maddinedi, Tammina Sai Kumar, Pavithra Madhiyazhagan, Asit Ranjan Ghosh. Antimicrobial and antioxidant activities of Mimusops elengi seed extract mediated isotropic silver nanoparticles. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2014 Sep; 130(?):13-8. doi: 10.1016/j.saa.2014.03.024. [PMID: 24759779]
  • William Sinko, Yang Wang, Wei Zhu, Yonghui Zhang, Ferran Feixas, Courtney L Cox, Douglas A Mitchell, Eric Oldfield, J Andrew McCammon. Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads. Journal of medicinal chemistry. 2014 Jul; 57(13):5693-701. doi: 10.1021/jm5004649. [PMID: 24827744]
  • Pierre Henri Rolland, Joel L Berry, Guillaume Louis, Lionel Velly, Vincent Vidal, Pauline Brige, Vinuta Mayakonda, David L Carroll. A nanoengineered embolic agent for precise radiofrequency ablation. Annals of biomedical engineering. 2014 May; 42(5):940-9. doi: 10.1007/s10439-014-0977-9. [PMID: 24449052]
  • Myeong Hyeon Park, In Sook Kim, Sun-A Kim, Chun-Soo Na, Cheol Yi Hong, Mi-Sook Dong, Hye Hyun Yoo. Inhibitory effect of Rhus verniciflua Stokes extract on human aromatase activity; butin is its major bioactive component. Bioorganic & medicinal chemistry letters. 2014 Apr; 24(7):1730-3. doi: 10.1016/j.bmcl.2014.02.039. [PMID: 24630560]
  • Pankaj Kumar Arora, Alok Srivastava, Vijay Pal Singh. Degradation of 4-chloro-3-nitrophenol via a novel intermediate, 4-chlororesorcinol by Pseudomonas sp. JHN. Scientific reports. 2014 Mar; 4(?):4475. doi: 10.1038/srep04475. [PMID: 24667329]
  • D A Sampietro, C M Jimenez, M M Belizán, M A Vattuone, C A N Catalán. Development and validation of a micromethod for fast quantification of 5-n-alkylresorcinols in grains and whole grain products. Food chemistry. 2013 Dec; 141(4):3546-51. doi: 10.1016/j.foodchem.2013.06.069. [PMID: 23993519]
  • Da Wo, Ping Zhuang, Zeng-guang Xu, Shumin Xu, Ying Lu, Hui-ming Mao. A novel spectrophotometric method for indirect determination of nitric oxide (NO) in serum. Clinica chimica acta; international journal of clinical chemistry. 2013 Sep; 424(?):187-90. doi: 10.1016/j.cca.2013.06.008. [PMID: 23791768]
  • Claudia E Calderón, Alejandro Pérez-García, Antonio de Vicente, Francisco M Cazorla. The dar genes of Pseudomonas chlororaphis PCL1606 are crucial for biocontrol activity via production of the antifungal compound 2-hexyl, 5-propyl resorcinol. Molecular plant-microbe interactions : MPMI. 2013 May; 26(5):554-65. doi: 10.1094/mpmi-01-13-0012-r. [PMID: 23547906]
  • Jo-Anne C H Tan, Michael G K Jones, John Fosu-Nyarko. Gene silencing in root lesion nematodes (Pratylenchus spp.) significantly reduces reproduction in a plant host. Experimental parasitology. 2013 Feb; 133(2):166-78. doi: 10.1016/j.exppara.2012.11.011. [PMID: 23201220]
  • E Ortega-Gómez, P Fernández-Ibáñez, M M Ballesteros Martín, M I Polo-López, B Esteban García, J A Sánchez Pérez. Water disinfection using photo-Fenton: Effect of temperature on Enterococcus faecalis survival. Water research. 2012 Nov; 46(18):6154-62. doi: 10.1016/j.watres.2012.09.007. [PMID: 23021523]
  • Mustafa Özyürek, Burcu Bekdeşer, Kubilay Güçlü, Reşat Apak. Resorcinol as a spectrofluorometric probe for the hypochlorous acid scavenging activity assay of biological samples. Analytical chemistry. 2012 Nov; 84(21):9529-36. doi: 10.1021/ac302369p. [PMID: 23046424]
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