Chorismate (BioDeep_00000003941)

 

Secondary id: BioDeep_00001868720

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(3R,4R)-3-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid

化学式: C10H10O6 (226.04773600000001)
中文名称: 氯磺酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.29%

分子结构信息

SMILES: C1=C[C@H]([C@@H](C=C1C(=O)O)OC(=C)C(=O)O)O
InChI: InChI=1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1

描述信息

Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and microorganisms. It is a precursor for the aromatic amino acids phenylalanine and tyrosine,indole, indole derivatives and tryptophan,2,3-dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis,the plant hormone salicylic acid and many alkaloids and other aromatic metabolites. -- Wikipedia [HMDB]. Chorismate is found in many foods, some of which are pigeon pea, ucuhuba, beech nut, and fireweed.
Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and microorganisms. It is a precursor for the aromatic amino acids phenylalanine and tyrosine,indole, indole derivatives and tryptophan,2,3-dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis,the plant hormone salicylic acid and many alkaloids and other aromatic metabolites. -- Wikipedia.
CONFIDENCE standard compound; INTERNAL_ID 114

同义名列表

14 个代谢物同义名

(3R,4R)-3-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid; (3R-trans)-3-((1-Carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid; (3R,4R)-3-[(1-Carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid; (3R,4R)-3-[(1-Carboxyethenyl)oxy]-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid; (3R-trans)-3-(1-Carboxyvinyloxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid; (3R-trans)-3-((1-Carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylate; (3R,4R)-3-[(1-Carboxyvinyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid; (3R,4R)-3-[(1-Carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylate; (3R,4R)-3-[(1-Carboxyvinyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylate; (-)-Chorismic acid; Acid, chorismic; Chorismic acid; SCHEMBL2619122; Chorismate



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(2)

PlantCyc(0)

代谢反应

700 个相关的代谢反应过程信息。

Reactome(2)

BioCyc(7)

WikiPathways(2)

Plant Reactome(659)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(30)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Wei Li, Jinyu He, Xiuzhuo Wang, Matthew Ashline, Zirui Wu, Fengquan Liu, Zheng Qing Fu, Ming Chang. PBS3: a versatile player in and beyond salicylic acid biosynthesis in Arabidopsis. The New phytologist. 2023 01; 237(2):414-422. doi: 10.1111/nph.18558. [PMID: 36263689]
  • Ravikumar R Patel, Disha D Patel, Jaimika Bhatt, Parth Thakor, Lindsay R Triplett, Vasudev R Thakkar. Induction of pre-chorismate, jasmonate and salicylate pathways by Burkholderia sp. RR18 in peanut seedlings. Journal of applied microbiology. 2021 Sep; 131(3):1417-1430. doi: 10.1111/jam.15019. [PMID: 33522007]
  • Estanislao Burgos, Maria Belen De Luca, Isidore Diouf, Luis A de Haro, Elise Albert, Christopher Sauvage, Zhao J Tao, Luisa Bermudez, Ramon Asís, Adriano N Nesi, Michel Matringe, Claire Bréhélin, Thomas Guiraud, Carine Ferrand, Isabelle Atienza, Joana Jorly, Jean P Mauxion, Pierre Baldet, Alisdair R Fernie, Leandro Quadrana, Christophe Rothan, Mathilde Causse, Fernando Carrari. Validated MAGIC and GWAS population mapping reveals the link between vitamin E content and natural variation in chorismate metabolism in tomato. The Plant journal : for cell and molecular biology. 2021 02; 105(4):907-923. doi: 10.1111/tpj.15077. [PMID: 33179365]
  • Wenfang Lin, Hong Zhang, Dongmei Huang, Dirk Schenke, Daguang Cai, Binghua Wu, Ying Miao. Dual-Localized WHIRLY1 Affects Salicylic Acid Biosynthesis via Coordination of ISOCHORISMATE SYNTHASE1, PHENYLALANINE AMMONIA LYASE1, and S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE1. Plant physiology. 2020 12; 184(4):1884-1899. doi: 10.1104/pp.20.00964. [PMID: 32900979]
  • Amna Mhamdi. Here, There, and Everywhere: Plastid- and Nuclear-Localized WHIRLY1 Regulates Salicylic Acid Homeostasis during Developmental Senescence. Plant physiology. 2020 12; 184(4):1620-1621. doi: 10.1104/pp.20.01475. [PMID: 33277328]
  • Zhu Li, Huiying Wang, Dongqin Ding, Yongfei Liu, Huan Fang, Zhishuai Chang, Tao Chen, Dawei Zhang. Metabolic engineering of Escherichia coli for production of chemicals derived from the shikimate pathway. Journal of industrial microbiology & biotechnology. 2020 Jul; 47(6-7):525-535. doi: 10.1007/s10295-020-02288-2. [PMID: 32642925]
  • Michael P Torrens-Spence, Anastassia Bobokalonova, Valentina Carballo, Christopher M Glinkerman, Tomáš Pluskal, Amber Shen, Jing-Ke Weng. PBS3 and EPS1 Complete Salicylic Acid Biosynthesis from Isochorismate in Arabidopsis. Molecular plant. 2019 12; 12(12):1577-1586. doi: 10.1016/j.molp.2019.11.005. [PMID: 31760159]
  • Yongkun Lv, Monireh Marsafari, Mattheos Koffas, Jingwen Zhou, Peng Xu. Optimizing Oleaginous Yeast Cell Factories for Flavonoids and Hydroxylated Flavonoids Biosynthesis. ACS synthetic biology. 2019 11; 8(11):2514-2523. doi: 10.1021/acssynbio.9b00193. [PMID: 31622552]
  • Cynthia K Holland, Corey S Westfall, Jason E Schaffer, Alejandro De Santiago, Chloe Zubieta, Sophie Alvarez, Joseph M Jez. Brassicaceae-specific Gretchen Hagen 3 acyl acid amido synthetases conjugate amino acids to chorismate, a precursor of aromatic amino acids and salicylic acid. The Journal of biological chemistry. 2019 11; 294(45):16855-16864. doi: 10.1074/jbc.ra119.009949. [PMID: 31575658]
  • Dmitrij Rekhter, Daniel Lüdke, Yuli Ding, Kirstin Feussner, Krzysztof Zienkiewicz, Volker Lipka, Marcel Wiermer, Yuelin Zhang, Ivo Feussner. Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid. Science (New York, N.Y.). 2019 08; 365(6452):498-502. doi: 10.1126/science.aaw1720. [PMID: 31371615]
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  • Yingjie Zhou, Johan Memelink, Huub J M Linthorst. An E. coli biosensor for screening of cDNA libraries for isochorismate pyruvate lyase-encoding cDNAs. Molecular genetics and genomics : MGG. 2018 Oct; 293(5):1181-1190. doi: 10.1007/s00438-018-1450-5. [PMID: 29796759]
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  • Xiaoyan Wang, Jiong Gao, Zheng Zhu, Xianxin Dong, Xiaolei Wang, Guodong Ren, Xin Zhou, Benke Kuai. TCP transcription factors are critical for the coordinated regulation of isochorismate synthase 1 expression in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2015 Apr; 82(1):151-62. doi: 10.1111/tpj.12803. [PMID: 25702611]
  • Marina Eremina, Wilfried Rozhon, Saiqi Yang, Brigitte Poppenberger. ENO2 activity is required for the development and reproductive success of plants, and is feedback-repressed by AtMBP-1. The Plant journal : for cell and molecular biology. 2015 Mar; 81(6):895-906. doi: 10.1111/tpj.12775. [PMID: 25620024]
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  • Christian Pfaff, Niels Glindemann, Jens Gruber, Margrit Frentzen, Radin Sadre. Chorismate pyruvate-lyase and 4-hydroxy-3-solanesylbenzoate decarboxylase are required for plastoquinone biosynthesis in the cyanobacterium Synechocystis sp. PCC6803. The Journal of biological chemistry. 2014 Jan; 289(5):2675-86. doi: 10.1074/jbc.m113.511709. [PMID: 24337576]
  • Jon Lucas Boatwright, Karolina Pajerowska-Mukhtar. Salicylic acid: an old hormone up to new tricks. Molecular plant pathology. 2013 Aug; 14(6):623-34. doi: 10.1111/mpp.12035. [PMID: 23621321]
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