5alpha-Cholestane (BioDeep_00000003876)

 

Secondary id: BioDeep_00001869563

human metabolite Endogenous


代谢物信息卡片


(1S,2S,7R,10R,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane

化学式: C27H48 (372.3756)
中文名称: 5α-胆甾烷
谱图信息: 最多检出来源 Homo sapiens(not specific) 1.84%

分子结构信息

SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C
InChI: InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1

描述信息

5alpha-Cholestane is found in potato. Cholestane is a saturated 27-carbon steroid precursor which serves as the basis for many organic molecules. (Wikipedia).
Cholestane is a saturated 27-carbon steroid precursor which serves as the basis for many organic molecules. 5alpha-Cholestane is found in potato.

同义名列表

16 个代谢物同义名

(1S,2S,7R,10R,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane; 28,29,30-Trinorlanostane; 5alpha-Cholestane (8ci); (5alpha)-Cholestane; 5alpha-Cholestane; alpha-Cholestane; (5a)-Cholestane; (5Α)-cholestane; 5|A-cholestane; 5Α-cholestane; 5a-Cholestane; a-Cholestane; Α-cholestane; Cholestane; Cholesten; Cholestane



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 ANXA5, APOE, BCL2, CASP3, CYP3A4, MTOR, NOS3, NT5C2, PIK3CA, PIK3R6, PTGS2, PTK2B, PTPN1, SGCB
Peripheral membrane protein 6 ANXA5, CYP1B1, MTOR, PIK3R6, PTGS2, PTPN1
Endosome membrane 1 LDLR
Endoplasmic reticulum membrane 7 BCL2, CYP1B1, CYP3A4, HMGCR, MTOR, PTGS2, PTPN1
Nucleus 6 APOE, BCL2, CASP3, MTOR, NOS3, PTK2B
cytosol 11 ANXA5, BCL2, CASP3, MTOR, NOS3, NT5C2, PIK3CA, PIK3R6, PTK2B, PTPN1, RICTOR
dendrite 3 APOE, MTOR, PTK2B
phagocytic vesicle 1 MTOR
nucleoplasm 3 CASP3, MTOR, NOS3
Cell membrane 2 LDLR, PIK3R6
Cytoplasmic side 2 MTOR, PTPN1
lamellipodium 2 PIK3CA, PTK2B
Multi-pass membrane protein 1 HMGCR
Golgi apparatus membrane 1 MTOR
cell cortex 1 PTK2B
cell surface 1 LDLR
glutamatergic synapse 4 APOE, CASP3, PTK2B, PTPN1
Golgi apparatus 4 APOE, LDLR, NOS3, RICTOR
Golgi membrane 3 INS, MTOR, NOS3
growth cone 1 PTK2B
lysosomal membrane 1 MTOR
neuronal cell body 3 APOE, CASP3, PTK2B
postsynapse 1 PTPN1
sarcolemma 2 ANXA5, SGCB
Cytoplasm, cytosol 1 NT5C2
Lysosome 2 LDLR, MTOR
Presynapse 1 PTK2B
plasma membrane 8 APOE, LDLR, NOS3, PIK3CA, PIK3R6, PTK2B, SGCB, SLC10A2
Membrane 10 ANXA5, APOE, BCL2, CYP1B1, CYP3A4, HMGCR, LDLR, MTOR, PIK3R6, PTPN1
apical plasma membrane 1 SLC10A2
basolateral plasma membrane 1 LDLR
caveola 2 NOS3, PTGS2
extracellular exosome 2 ANXA5, APOE
Lysosome membrane 1 MTOR
endoplasmic reticulum 5 APOE, BCL2, HMGCR, PTGS2, PTPN1
extracellular space 2 APOE, INS
perinuclear region of cytoplasm 3 NOS3, PIK3CA, PTK2B
Schaffer collateral - CA1 synapse 1 PTK2B
intercalated disc 1 PIK3CA
mitochondrion 2 BCL2, CYP1B1
protein-containing complex 3 BCL2, PTGS2, PTPN1
intracellular membrane-bounded organelle 2 CYP1B1, CYP3A4
Microsome membrane 4 CYP1B1, CYP3A4, MTOR, PTGS2
postsynaptic density 2 CASP3, PTK2B
TORC1 complex 1 MTOR
TORC2 complex 2 MTOR, RICTOR
Single-pass type I membrane protein 1 LDLR
Secreted 2 APOE, INS
extracellular region 3 ANXA5, APOE, INS
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 2 BCL2, LDLR
mitochondrial outer membrane 2 BCL2, MTOR
mitochondrial matrix 1 PTPN1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 ANXA5, LDLR
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 2 APOE, LDLR
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
dendritic spine 1 PTK2B
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
Early endosome 3 APOE, LDLR, PTPN1
Membrane, clathrin-coated pit 1 LDLR
apical part of cell 1 LDLR
clathrin-coated pit 1 LDLR
Single-pass type II membrane protein 1 SGCB
Cell membrane, sarcolemma 1 SGCB
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 SGCB
focal adhesion 2 ANXA5, PTK2B
extracellular matrix 1 APOE
peroxisomal membrane 1 HMGCR
Nucleus, PML body 1 MTOR
PML body 1 MTOR
collagen-containing extracellular matrix 2 ANXA5, APOE
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 LDLR
receptor complex 1 LDLR
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
cytoskeleton 3 NOS3, PTK2B, SGCB
mitochondrial crista 1 PTPN1
Secreted, extracellular space 1 APOE
blood microparticle 1 APOE
postsynaptic density, intracellular component 1 PTK2B
nuclear envelope 1 MTOR
Endomembrane system 3 LDLR, MTOR, PTPN1
endosome lumen 2 INS, PTPN1
sorting endosome 2 LDLR, PTPN1
microvillus 1 SLC10A2
Melanosome 1 APOE
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
cell body 1 PTK2B
myelin sheath 1 BCL2
Peroxisome membrane 1 HMGCR
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 APOE, INS, PTGS2
phosphatidylinositol 3-kinase complex 2 PIK3CA, PIK3R6
phosphatidylinositol 3-kinase complex, class IA 2 PIK3CA, PIK3R6
endocytic vesicle membrane 1 NOS3
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 2 APOE, LDLR
synaptic cleft 1 APOE
NMDA selective glutamate receptor complex 1 PTK2B
endolysosome membrane 1 LDLR
apical dendrite 1 PTK2B
death-inducing signaling complex 1 CASP3
dystrophin-associated glycoprotein complex 1 SGCB
sarcoglycan complex 1 SGCB
somatodendritic compartment 1 LDLR
Cytoplasmic vesicle, phagosome 1 MTOR
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 1 APOE
PCSK9-LDLR complex 1 LDLR
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
cytoplasmic side of endoplasmic reticulum membrane 1 PTPN1
phosphatidylinositol 3-kinase complex, class IB 2 PIK3CA, PIK3R6


文献列表

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