Semicarbazide (BioDeep_00000003483)
Secondary id: BioDeep_00001868234
human metabolite blood metabolite
代谢物信息卡片
Carbamylhydrazine monohydrochloride
化学式: CH5N3O (75.04326)
中文名称: 氨基脲
谱图信息:
最多检出来源 Homo sapiens(blood) 96.67%
分子结构信息
SMILES: C(=O)(N)NN
InChI: InChI=1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)
描述信息
D009676 - Noxae > D002273 - Carcinogens
KEIO_ID S034
同义名列表
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:28306
- KEGG: C02077
- KEGGdrug: D95915
- PubChem: 5196
- HMDB: HMDB0258225
- Metlin: METLIN65708
- ChEMBL: CHEMBL903
- Wikipedia: Semicarbazide
- MetaCyc: SEMICARBAZIDE
- chemspider: 5008
- CAS: 57-56-7
- MoNA: KO004007
- MoNA: KO004008
- MoNA: KO004010
- MoNA: KO004011
- MoNA: KO004009
- PMhub: MS000009743
- PubChem: 5163
- NIKKAJI: J4.582I
- RefMet: Semicarbazide
分类词条
相关代谢途径
Reactome(0)
BioCyc(9)
- trans-4-hydroxy-L-proline degradation II
- L-arginine degradation VIII (arginine oxidase pathway)
- methanol and methylamine oxidation to formaldehyde
- superpathway of C1 compounds oxidation to CO2
- formaldehyde assimilation I (serine pathway)
- methylamine degradation I
- CMP-N-acetylneuraminate biosynthesis II (bacteria)
- superpathway of CMP-sialic acids biosynthesis
- spermidine biosynthesis I
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Yi-Jun Shi, Jing-Ting Chiou, Liang-Jun Wang, Chia-Hui Huang, Yuan-Chin Lee, Ying-Jung Chen, Long-Sen Chang. Blocking of negative charged carboxyl groups converts Naja atra neurotoxin to cardiotoxin-like protein.
International journal of biological macromolecules.
2020 Dec; 164(?):2953-2963. doi:
10.1016/j.ijbiomac.2020.08.163. [PMID: 32846183] - Jinyan Gong, Jiong Li, Haina Yuan, Bingquan Chu, Weijie Lin, Qingwen Cao, Qiqi Zhao, Ruosi Fang, Ling Li, Gongnian Xiao. Determination of four nitrofuran metabolites in gelatin Chinese medicine using dispersive solid phase extraction and pass-through solid phase extraction coupled to ultra high performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jun; 1146(?):122018. doi:
10.1016/j.jchromb.2020.122018. [PMID: 32334390] - Michael J Reid, Russell Eyre, Terry Podoll. Oxidative Deamination of Emixustat by Human Vascular Adhesion Protein-1/Semicarbazide-Sensitive Amine Oxidase.
Drug metabolism and disposition: the biological fate of chemicals.
2019 05; 47(5):504-515. doi:
10.1124/dmd.118.085811. [PMID: 30787099] - Zonghao Yue, Miao Yu, Xiaona Zhang, Jun Wang, Shaoguo Ru. The anti-androgenic effect of chronic exposure to semicarbazide on male Japanese flounder (Paralichthys olivaceus) and its potential mechanisms.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2018 Aug; 210(?):30-34. doi:
10.1016/j.cbpc.2018.04.005. [PMID: 29729480] - Zonghao Yue, Miao Yu, Haifeng Zhao, Jun Wang, Xiaona Zhang, Hua Tian, Wei Wang, Shaoguo Ru. The anti-estrogenicity of chronic exposure to semicarbazide in female Japanese flounders (Paralichthys olivaceus), and its potential mechanisms.
Marine pollution bulletin.
2018 Apr; 129(2):806-812. doi:
10.1016/j.marpolbul.2017.10.081. [PMID: 29100632] - Miao Yu, Yongliang Feng, Xiaona Zhang, Jun Wang, Hua Tian, Wei Wang, Shaoguo Ru. Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system.
Reproductive toxicology (Elmsford, N.Y.).
2017 10; 73(?):149-157. doi:
10.1016/j.reprotox.2017.08.007. [PMID: 28834696] - Yuh-Hwa Liu, Yeh-Lin Lu, Der-Zen Liu, Wen-Chi Hou. Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro.
Drug design, development and therapy.
2017; 11(?):2139-2147. doi:
10.2147/dddt.s141740. [PMID: 28761331] - Xing Liu, Yuan-Fu Lu, Xinfu Guan, Mingkun Zhao, Jin Wang, Feng Li. Characterizing novel metabolic pathways of melatonin receptor agonist agomelatine using metabolomic approaches.
Biochemical pharmacology.
2016 06; 109(?):70-82. doi:
10.1016/j.bcp.2016.03.020. [PMID: 27021842] - Miao Zhang, Limin Liu, Feng Zhi, Panpan Niu, Mengya Yang, Xuemei Zhu, Ying Diao, Yanmei Li, Jun Wang, Ying Zhao. Inactivation of semicarbazide-sensitive amine oxidase induces the phenotypic switch of smooth muscle cells and aggravates the development of atherosclerotic lesions.
Atherosclerosis.
2016 06; 249(?):76-82. doi:
10.1016/j.atherosclerosis.2016.03.039. [PMID: 27065245] - O O Gudkova, N V Latyshko, S G Shandrenko. Amine oxidases as important agents of pathological processes of rhabdomyolysis in rats.
Ukrainian biochemical journal.
2016 Jan; 88(1):79-87. doi:
10.15407/ubj88.01.079. [PMID: 29227084] - May Wong, Sonia Saad, Jie Zhang, Simon Gross, Wolfgang Jarolimek, Heidi Schilter, Jason A Chen, Anthony J Gill, Carol A Pollock, Muh Geot Wong. Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model.
American journal of physiology. Renal physiology.
2014 Oct; 307(8):F908-16. doi:
10.1152/ajprenal.00698.2013. [PMID: 25143459] - L M Petrun'. [Effect of semicarbazide on the peroxidation processes and Lewis carcinoma growth in mice].
Ukrainian biochemical journal.
2014 Jul; 86(4):158-63. doi:
10.15407/ubj86.04.158. [PMID: 25509195] - Tae-Won Kim, In-Bae Song, Hong-Ki Lee, Jong-Hwan Lim, Eun-Sang Cho, Hwa-Young Son, Sang-Jin Park, Jong-Woo Kim, Hyo-In Yun. Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Dec; 50(12):4254-9. doi:
10.1016/j.fct.2012.05.022. [PMID: 22617354] - Jie Xu, Zhanting Li, Min Cao, Han Zhang, Jifeng Sun, Jie Zhao, Qiang Zhou, Zhifen Wu, Lianjia Yang. Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with andrographolide.
International journal of biological macromolecules.
2012 Dec; 51(5):738-42. doi:
10.1016/j.ijbiomac.2012.06.035. [PMID: 22766034] - Filiz Ozcan, Asli Ozmen, Bahar Akkaya, Yakup Aliciguzel, Mutay Aslan. Beneficial effect of myricetin on renal functions in streptozotocin-induced diabetes.
Clinical and experimental medicine.
2012 Dec; 12(4):265-72. doi:
10.1007/s10238-011-0167-0. [PMID: 22083509] - Fatemeh Shaki, Mir-Jamal Hosseini, Mahmoud Ghazi-Khansari, Jalal Pourahmad. Toxicity of depleted uranium on isolated rat kidney mitochondria.
Biochimica et biophysica acta.
2012 Dec; 1820(12):1940-50. doi:
10.1016/j.bbagen.2012.08.015. [PMID: 22940002] - R C Ezeokonkwo, I O Ezeh, J I Onunkwo, I W Onyenwe, C N Iheagwam, W E Agu. Comparative serum biochemical changes in mongrel dogs following single and mixed infections of Trypanosoma congolense and Trypanosoma brucei brucei.
Veterinary parasitology.
2012 Nov; 190(1-2):56-61. doi:
10.1016/j.vetpar.2012.05.012. [PMID: 22694831] - Scott P Henry, Mark Johnson, Thomas A Zanardi, Robert Fey, Diana Auyeung, Patrick B Lappin, Arthur A Levin. Renal uptake and tolerability of a 2'-O-methoxyethyl modified antisense oligonucleotide (ISIS 113715) in monkey.
Toxicology.
2012 Nov; 301(1-3):13-20. doi:
10.1016/j.tox.2012.06.005. [PMID: 22709826] - Jing Liu, Ju-xiang Liu, San-ni Xu, Jin-xing Quan, Li-min Tian, Qian Guo, Jia Liu, Yun-fang Wang, Zhi-yong Shi. Association of P213S polymorphism of the L-selectin gene with type 2 diabetes and insulin resistance in Chinese population.
Gene.
2012 Nov; 509(2):286-90. doi:
10.1016/j.gene.2012.07.086. [PMID: 22921892] - Zhanting Li, Libing Zhu, Han Zhang, Jie Yang, Jie Zhao, Dewei Du, Junping Meng, Feng Yang, Yanlong Zhao, Jifeng Sun. Protective effect of a polysaccharide from stem of Codonopsis pilosula against renal ischemia/reperfusion injury in rats.
Carbohydrate polymers.
2012 Nov; 90(4):1739-43. doi:
10.1016/j.carbpol.2012.07.062. [PMID: 22944441] - Maria Patarroyo, Edgard Wehbe, Mazen Hanna, David O Taylor, Randall C Starling, Sevag Demirjian, W H Wilson Tang. Cardiorenal outcomes after slow continuous ultrafiltration therapy in refractory patients with advanced decompensated heart failure.
Journal of the American College of Cardiology.
2012 Nov; 60(19):1906-12. doi:
10.1016/j.jacc.2012.08.957. [PMID: 23062527] - Hui-hui Hao, Zhu-min Shao, Dao-quan Tang, Qian Lu, Xu Chen, Xiao-xing Yin, Jing Wu, Hui Chen. Preventive effects of rutin on the development of experimental diabetic nephropathy in rats.
Life sciences.
2012 Nov; 91(19-20):959-67. doi:
10.1016/j.lfs.2012.09.003. [PMID: 23000098] - Scott I Aydin, Howard S Seiden, Andrew D Blaufox, Vincent A Parnell, Tarif Choudhury, Ann Punnoose, James Schneider. Acute kidney injury after surgery for congenital heart disease.
The Annals of thoracic surgery.
2012 Nov; 94(5):1589-95. doi:
10.1016/j.athoracsur.2012.06.050. [PMID: 22884599] - Tai-Long Pan, Pei-Wen Wang, Saleh A Al-Suwayeh, Yi-Ju Huang, Jia-You Fang. Toxicological effects of cationic nanobubbles on the liver and kidneys: biomarkers for predicting the risk.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Nov; 50(11):3892-901. doi:
10.1016/j.fct.2012.07.005. [PMID: 22809472] - Xiao-Hua Guo, Zhi-Dan Zhao, Hyang-Mi Nam, Jae-Myung Kim. Comparative evaluation of three Lactobacilli with strain-specific activities for rats when supplied in drinking water.
Antonie van Leeuwenhoek.
2012 Nov; 102(4):561-8. doi:
10.1007/s10482-012-9751-x. [PMID: 22622624] - L Xiao, M Xiao, X Jin, K Kawasaki, N Ohta, E Sakaguchi. Transfer of blood urea nitrogen to cecal microbial nitrogen is increased by mannitol feeding in growing rabbits fed timothy hay diet.
Animal : an international journal of animal bioscience.
2012 Nov; 6(11):1757-63. doi:
10.1017/s1751731112000754. [PMID: 22717322] - Oyagbemi Ademola Adetokunbo, Azeez Odunayo Ibraheem, Iji Oluwafikemi Temitayo. The effect of prolonged oral exposure of cockerels to disinfectant (Iodosteryl(®)) on induction of oxidative stress and liver damage.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Nov; 64(7-8):883-7. doi:
10.1016/j.etp.2011.03.011. [PMID: 21514805] - Jessy J Alexander, Lee Chaves, Anthony Chang, Richard J Quigg. The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice.
Kidney international.
2012 Nov; 82(9):961-8. doi:
10.1038/ki.2012.249. [PMID: 22832515] - Yuko Togashi, Yuka Sakaguchi, Mari Miyamoto, Yohei Miyamoto. Urinary cystatin C as a biomarker for acute kidney injury and its immunohistochemical localization in kidney in the CDDP-treated rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Nov; 64(7-8):797-805. doi:
10.1016/j.etp.2011.01.018. [PMID: 21377848] - Hideki Masuda, Yasuo Takahashi, Yayoi Nishida, Satoshi Asai. Comparison of the effect of mesalazine and sulfasalazine on laboratory parameters: a retrospective observational study.
European journal of clinical pharmacology.
2012 Nov; 68(11):1549-55. doi:
10.1007/s00228-012-1289-3. [PMID: 22546896] - Tao Liu, Qiang Meng, Changyuan Wang, Qi Liu, Xinjin Guo, Huijun Sun, Jinyong Peng, Xiaochi Ma, Taiichi Kaku, Kexin Liu. Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats.
Toxicology and applied pharmacology.
2012 Nov; 264(3):423-30. doi:
10.1016/j.taap.2012.08.019. [PMID: 22992436] - Tao Du, Jun Cheng, Liang Zhong, Xin-Feng Zhao, Jiang Zhu, Ying-Jian Zhu, Guo-Hua Liu. The alleviation of acute and chronic kidney injury by human Wharton's jelly-derived mesenchymal stromal cells triggered by ischemia-reperfusion injury via an endocrine mechanism.
Cytotherapy.
2012 Nov; 14(10):1215-27. doi:
10.3109/14653249.2012.711471. [PMID: 22920838] - Jin Nam Kim, In Youb Chang, Jin Hwa Kim, Jung Woo Kim, Kyeong-Soo Park, Hyun Il Kim, Sang Pil Yoon. The role of apurinic/apyrimidinic endonuclease on the progression of streptozotocin-induced diabetic nephropathy in rats.
Acta histochemica.
2012 Nov; 114(7):647-52. doi:
10.1016/j.acthis.2011.11.011. [PMID: 22172708] - Jing-min Ou, Xi-ping Zhang, Cheng-jun Wu, Di-jiong Wu, Ping Yan. Effects of dexamethasone and Salvia miltiorrhiza on multiple organs in rats with severe acute pancreatitis.
Journal of Zhejiang University. Science. B.
2012 Nov; 13(11):919-31. doi:
10.1631/jzus.b1100351. [PMID: 23125085] - Craig H Warden, Rodrigo Gularte-Mérida, Janis S Fisler, Susan Hansen, Noreene Shibata, Anh Le, Juan F Medrano, Judith S Stern. Leptin receptor interacts with rat chromosome 1 to regulate renal disease traits.
Physiological genomics.
2012 Nov; 44(21):1052-62. doi:
10.1152/physiolgenomics.00134.2011. [PMID: 22968639] - Hanan H Hagar, Raeesa Abd El Tawab. Cysteinyl leukotriene receptor antagonism alleviates renal injury induced by ischemia-reperfusion in rats.
The Journal of surgical research.
2012 Nov; 178(1):e25-34. doi:
10.1016/j.jss.2012.02.022. [PMID: 22487384] - Jia Yu, Wenhong Deng, Weixing Wang, Youming Ding, Hao Jin, Chen Chen, Xiaoyan Chen, Xingcheng Xiong, Sheng Xu. Inhibition of poly(ADP-ribose) polymerase attenuates acute kidney injury in sodium taurocholate-induced acute pancreatitis in rats.
Pancreas.
2012 Nov; 41(8):1299-305. doi:
10.1097/mpa.0b013e318252dbc3. [PMID: 22750969] - Honglin Hu, Cong Zou, Xiaoqing Xi, Ziming Shi, Gongxian Wang, Xueming Huang. Protective effects of pioglitazone on renal ischemia-reperfusion injury in mice.
The Journal of surgical research.
2012 Nov; 178(1):460-5. doi:
10.1016/j.jss.2012.01.012. [PMID: 22507688] - Yan-Yan Xu, Na Jiang, Tong-Shen Liu, Hui-Qing Qu, Tian Wang. Evaluation of the effect of glutathione on cisplatin antitumor activity and kidney injury at different administration times.
Molecular medicine reports.
2012 11; 6(5):1075-80. doi:
10.3892/mmr.2012.1033. [PMID: 22895541] - Allen P Kaplan. Treatment of chronic spontaneous urticaria.
Allergy, asthma & immunology research.
2012 Nov; 4(6):326-31. doi:
10.4168/aair.2012.4.6.326. [PMID: 23115728] - Yuying Liu, Grant Bledsoe, Makato Hagiwara, Bo Shen, Lee Chao, Julie Chao. Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling.
American journal of physiology. Renal physiology.
2012 Oct; 303(8):F1230-8. doi:
10.1152/ajprenal.00257.2012. [PMID: 22811485] - Yun-Wei Shi, Cai-Ping Wang, Xing Wang, Yuan-Li Zhang, Lei Liu, Ru-Wei Wang, Jian-Feng Ye, Lin-Shui Hu, Ling-Dong Kong. Uricosuric and nephroprotective properties of Ramulus Mori ethanol extract in hyperuricemic mice.
Journal of ethnopharmacology.
2012 Oct; 143(3):896-904. doi:
10.1016/j.jep.2012.08.023. [PMID: 22967667] - Rong-Guo Fu, Rong-Liang Xue, Jing Wang, Li-Qun Ma, Jian-Rui Lv, Li Wang, Gang-Lian Yao, Heng Ge, Zhao Chen, Zhao-Yang Duan, Yarong Wang. Uremic anorexia and ghrelin expression in the amygdala.
Neuroscience letters.
2012 Oct; 527(1):50-4. doi:
10.1016/j.neulet.2012.08.040. [PMID: 22960364] - Takeshi Kuroda, Naohito Tanabe, Daisuke Kobayashi, Yoko Wada, Shuichi Murakami, Masaaki Nakano, Ichiei Narita. Significant association between renal function and area of amyloid deposition in kidney biopsy specimens in reactive amyloidosis associated with rheumatoid arthritis.
Rheumatology international.
2012 Oct; 32(10):3155-62. doi:
10.1007/s00296-011-2148-8. [PMID: 21947375] - Ayodele Odutayo, Neill K J Adhikari, James Barton, Karen E A Burns, Jan O Friedrich, David Klein, Stephen Lapinsky, Sasha Litwin, Aleksander Meret, Rahim Moineddin, Bonnie Richardson, Robert Richardson, Alina Zaltzman, Michelle Hladunewich, Ron Wald. Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study.
Canadian journal of anaesthesia = Journal canadien d'anesthesie.
2012 Oct; 59(10):934-42. doi:
10.1007/s12630-012-9761-1. [PMID: 22843289] - R J Ramalho, P S T de Oliveira, R C Cavaglieri, C Silva, P R B Medeiros, D Martini Filho, L F Poli-de-Figueiredo, I L Noronha. Hyperbaric oxygen therapy induces kidney protection in an ischemia/reperfusion model in rats.
Transplantation proceedings.
2012 Oct; 44(8):2333-6. doi:
10.1016/j.transproceed.2012.07.020. [PMID: 23026586] - D R Tolleson, G E Carstens, T H Welsh, P D Teel, O F Strey, M T Longnecker, S D Prince, K K Banik. Plane of nutrition by tick-burden interaction in cattle: effect on growth and metabolism.
Journal of animal science.
2012 Oct; 90(10):3442-50. doi:
10.2527/jas.2011-5066. [PMID: 22665634] - M Heidarpour, S Soltani, M Mohri, J Khoshnegah. Canine visceral leishmaniasis: relationships between oxidative stress, liver and kidney variables, trace elements, and clinical status.
Parasitology research.
2012 Oct; 111(4):1491-6. doi:
10.1007/s00436-012-2985-8. [PMID: 22669694] - M W Khan, S Priyamvada, S A Khan, S Khan, A Naqshbandi, A N K Yusufi. Protective effect of ω-3 polyunsaturated fatty acids on L-arginine-induced nephrotoxicity and oxidative damage in rat kidney.
Human & experimental toxicology.
2012 Oct; 31(10):1022-34. doi:
10.1177/0960327112440110. [PMID: 22531969] - Harish Kumar Bishnoi, Nanjaian Mahadevan, Pitchai Balakumar. The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat.
Pharmacological research.
2012 Oct; 66(4):349-56. doi:
10.1016/j.phrs.2012.07.001. [PMID: 22796657] - Fernando Moya, Paula M Sisk, Kelly R Walsh, Carol Lynn Berseth. A new liquid human milk fortifier and linear growth in preterm infants.
Pediatrics.
2012 Oct; 130(4):e928-35. doi:
10.1542/peds.2011-3120. [PMID: 22987877] - Satoru Asano, Masuzoh Taneda, Keiichi Katoh, Kenshi Suzuki. Life-threatening hemorrhagic shock after laparoscopic surgery: a case of postoperative thrombotic thrombocytopenic purpura.
Journal of anesthesia.
2012 Oct; 26(5):766-9. doi:
10.1007/s00540-012-1392-8. [PMID: 22526435] - Petra Vinken, Sofie Starckx, Erio Barale-Thomas, Adriana Looszova, Manisha Sonee, Nick Goeminne, Loes Versmissen, Kristel Buyens, Ann Lampo. Tissue Kim-1 and urinary clusterin as early indicators of cisplatin-induced acute kidney injury in rats.
Toxicologic pathology.
2012 Oct; 40(7):1049-62. doi:
10.1177/0192623312444765. [PMID: 22581811] - Man Liu, Bo-Yan Gao, Fang Qin, Ping-Ping Wu, Hai-Ming Shi, Wei Luo, Ai-Niu Ma, Yuan-Rong Jiang, Xue-Bing Xu, Liang-Li Lucy Yu. Acute oral toxicity of 3-MCPD mono- and di-palmitic esters in Swiss mice and their cytotoxicity in NRK-52E rat kidney cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Oct; 50(10):3785-91. doi:
10.1016/j.fct.2012.07.038. [PMID: 22847132] - Chiung-Chi Peng, Chiu-Lan Hsieh, Yaw-Bee Ker, Hsi-Yi Wang, Kuan-Chou Chen, Robert Y Peng. Selected nutraceutic screening by therapeutic effects on doxorubicin-induced chronic kidney disease.
Molecular nutrition & food research.
2012 Oct; 56(10):1541-58. doi:
10.1002/mnfr.201200178. [PMID: 22945467] - Uzma Saleem, Bashir Ahmad, Kanwal Rehman, Saeed Mahmood, Maqsood Alam, Alia Erum. Nephro-protective effect of vitamin C and Nigella sativa oil on gentamicin associated nephrotoxicity in rabbits.
Pakistan journal of pharmaceutical sciences.
2012 Oct; 25(4):727-30. doi:
NULL. [PMID: 23009987] - Y Michigoshi, R Katayama, N Yamagishi, M Kato, J Saito, H Satoh, K Furuhama. Estimation of glomerular filtration rate in rabbits by a single-sample method using iodixanol.
Laboratory animals.
2012 Oct; 46(4):341-4. doi:
10.1258/la.2012.011065. [PMID: 23097569] - In-Chul Lee, Sung-Hwan Kim, Sang-Min Lee, Hyung-Seon Baek, Changjong Moon, Sung-Ho Kim, Seung-Chun Park, Hyoung-Chin Kim, Jong-Choon Kim. Melatonin attenuates gentamicin-induced nephrotoxicity and oxidative stress in rats.
Archives of toxicology.
2012 Oct; 86(10):1527-36. doi:
10.1007/s00204-012-0849-8. [PMID: 22526374] - J A Sabbia, K F Kalscheur, A D Garcia, A M Gehman, J M Tricarico. Soybean meal substitution with a yeast-derived microbial protein source in dairy cow diets.
Journal of dairy science.
2012 Oct; 95(10):5888-900. doi:
10.3168/jds.2011-5237. [PMID: 22863090] - M W Khan, S Priyamvada, S A Khan, S Khan, A Naqshbandi, A N K Yusufi. Protective effect of ω-3 polyunsaturated fatty acids (PUFAs) on sodium nitroprusside-induced nephrotoxicity and oxidative damage in rat kidney.
Human & experimental toxicology.
2012 Oct; 31(10):1035-49. doi:
10.1177/0960327112444475. [PMID: 22549094] - Eduardo Paredes-Andrade, Craig A Solid, Sarah B Rockswold, Rick M Odland, Gaylan L Rockswold. Hypertonic saline reduces intracranial hypertension in the presence of high serum and cerebrospinal fluid osmolalities.
Neurocritical care.
2012 Oct; 17(2):204-10. doi:
10.1007/s12028-011-9574-z. [PMID: 21725694] - David A Spector, Jie Deng, Kerry J Stewart. Dietary protein affects urea transport across rat urothelia.
American journal of physiology. Renal physiology.
2012 Oct; 303(7):F944-53. doi:
10.1152/ajprenal.00238.2012. [PMID: 22832927] - Thulasingam Senthilkumar, Nagarajan Sangeetha, Natarajan Ashokkumar. Antihyperglycemic, antihyperlipidemic, and renoprotective effects of Chlorella pyrenoidosa in diabetic rats exposed to cadmium.
Toxicology mechanisms and methods.
2012 Oct; 22(8):617-24. doi:
10.3109/15376516.2012.714007. [PMID: 22827700] - Sanyog Jain, Pankaj U Valvi, Nitin K Swarnakar, Kaushik Thanki. Gelatin coated hybrid lipid nanoparticles for oral delivery of amphotericin B.
Molecular pharmaceutics.
2012 Sep; 9(9):2542-53. doi:
10.1021/mp300320d. [PMID: 22845020] - Timothy K Cooper, Qing Zhong, Mary Nabity, Gerson Rosenberg, William J Weiss. Use of urinary biomarkers of renal ischemia in a lamb preclinical left ventricular assist device model.
Artificial organs.
2012 Sep; 36(9):820-4. doi:
10.1111/j.1525-1594.2011.01436.x. [PMID: 22428807] - Ileana Mackinney-Novelo, Josué Barahona-Garrido, Fátima Castillo-Albarran, Jean J Santiago-Hernández, Nahum Méndez-Sánchez, Misael Uribe, Norberto Chávez-Tapia. Clinical course and management of acute hepatitis A infection in adults.
Annals of hepatology.
2012 Sep; 11(5):652-7. doi:
10.1016/s1665-2681(19)31438-3. [PMID: 22947525] - Xi-Xin Wu. [Clinical comparison study of Chinese adult serum cystatin C based estimated glomerular filtration rate equations].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue.
2012 Sep; 24(9):530-3. doi:
NULL. [PMID: 22938660] - Shin Ahn, Yoon-Seon Lee, Yeon Hee Chun, Kyung Soo Lim, Won Kim, Jae-Lyun Lee. Predictive factors of bacteraemia in low-risk patients with febrile neutropenia.
Emergency medicine journal : EMJ.
2012 Sep; 29(9):715-9. doi:
10.1136/emermed-2011-200012. [PMID: 22011971] - Farzaneh Ashrafi, Mehdi Nematbakhsh, Tahereh Safari, Ardeshir Talebi, Hamid Nasri, Mehdi Khazaei, Mohammad-Mehdi Baradaran-Mahdavi, Amir Jafapisheh, Behrooz Olia, Omid Pirhaji, Sayyed-Javad Hashemi-Nia, Fatemeh Eshraghi, Zahra Pezeshki, Mojgan Mortazavi. A combination of vitamin C and losartan for cisplatin-induced nephrotoxicity in rats.
Iranian journal of kidney diseases.
2012 Sep; 6(5):361-5. doi:
NULL. [PMID: 22976262] - Selvinaz Dalaklioglu, Pinar Sahin, Ece Gungor Ordueri, Ciler Celik-Ozenci, Arda Tasatargil. Potential role of poly(ADP-ribose) polymerase (PARP) activation in methotrexate-induced nephrotoxicity and tubular apoptosis.
International journal of toxicology.
2012 Sep; 31(5):430-40. doi:
10.1177/1091581812457430. [PMID: 22914891] - Ming Li, Nanfu Luo, Zhixuan Bai, Shuren Wang, Yingkang Shi, Xian'en Fa. A canine model of multiple organ dysfunction following acute type-A aortic dissection.
Surgery today.
2012 Sep; 42(9):876-83. doi:
10.1007/s00595-011-0073-9. [PMID: 22120508] - Wei Li, Hong Jiang, Jiang-Min Feng. Isogenic mesenchymal stem cells transplantation improves a rat model of chronic aristolochic acid nephropathy via upregulation of hepatic growth factor and downregulation of transforming growth factor β1.
Molecular and cellular biochemistry.
2012 Sep; 368(1-2):137-45. doi:
10.1007/s11010-012-1352-5. [PMID: 22661380] - Emi Yamamato, Takeshi Izawa, Osamu Sawamoto, Vetnizah Juniantito, Mitsuru Kuwamura, Jyoji Yamate. Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Sep; 64(6):625-31. doi:
10.1016/j.etp.2010.12.005. [PMID: 21256724] - Matthias Dupont, Yuping Wu, Stanley L Hazen, W H Wilson Tang. Cystatin C identifies patients with stable chronic heart failure at increased risk for adverse cardiovascular events.
Circulation. Heart failure.
2012 Sep; 5(5):602-9. doi:
10.1161/circheartfailure.112.966960. [PMID: 22899766] - Talib Hussain, Ramesh K Gupta, K Sweety, Bavani Eswaran, M Vijayakumar, Chandana Venkateswara Rao. Nephroprotective activity of Solanum xanthocarpum fruit extract against gentamicin-induced nephrotoxicity and renal dysfunction in experimental rodents.
Asian Pacific journal of tropical medicine.
2012 Sep; 5(9):686-91. doi:
10.1016/s1995-7645(12)60107-2. [PMID: 22805718] - Juan-Pablo Idrovo, Weng-Lang Yang, Jeffrey Nicastro, Gene F Coppa, Ping Wang. Stimulation of carnitine palmitoyltransferase 1 improves renal function and attenuates tissue damage after ischemia/reperfusion.
The Journal of surgical research.
2012 Sep; 177(1):157-64. doi:
10.1016/j.jss.2012.05.053. [PMID: 22698429] - Mohammed Ahmed Saad Almansob, Bo Xu, Li Zhou, Xiao-Xia Hu, Wen Chen, Feng-Jun Chang, Hong-Bo Ci, Jian-Ping Yao, Ying-Qi Xu, Feng-Juan Yao, Dong-Hong Liu, Wen-Bo Zhang, Bai-Yun Tang, Zhi-Ping Wang, Jing-Song Ou. Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial.
Arteriosclerosis, thrombosis, and vascular biology.
2012 Sep; 32(9):2304-13. doi:
10.1161/atvbaha.112.252098. [PMID: 22796581] - Kubra Kaynar, Rezzan Aliyazioglu, Safak Ersoz, Sukru Ulusoy, Sait Al, Gulsum Ozkan, Muammer Cansiz. Role of erythropoietin in prevention of amikacin-induced nephropathy.
Journal of nephrology.
2012 Sep; 25(5):744-9. doi:
10.5301/jn.5000054. [PMID: 22322815] - Li-li Deng, Ling Zhong, Jian-rong Lei, Lin Tang, Ling Liu, Shu-qin Xie, Xiao-hui Liao. [Protective effect of lipoxin A4 against rhabdomyolysis-induced acute kidney injury in rats].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2012 Sep; 28(9):907-10. doi:
NULL. [PMID: 22980651] - Guangzhi Chen, Renfan Xu, Yinna Wang, Peihua Wang, Gang Zhao, Xizhen Xu, Artiom Gruzdev, Darryl C Zeldin, Dao Wen Wang. Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathy.
American journal of physiology. Endocrinology and metabolism.
2012 Sep; 303(5):E563-75. doi:
10.1152/ajpendo.00591.2011. [PMID: 22739108] - Shanshan Chen, Junbao Du, Yinfang Liang, Rongyuan Zhang, Chaoshu Tang, Hongfang Jin. Sulfur dioxide restores calcium homeostasis disturbance in rat with isoproterenol-induced myocardial injury.
Histology and histopathology.
2012 09; 27(9):1219-26. doi:
10.14670/hh-27.1219. [PMID: 22806909] - Chia-Yu Lin, Chia-Yun Lin, Mei-Chin Yin. Renal protective effects of extracts from guava fruit (Psidium guajava L.) in diabetic mice.
Plant foods for human nutrition (Dordrecht, Netherlands).
2012 Sep; 67(3):303-8. doi:
10.1007/s11130-012-0294-0. [PMID: 22581156] - Peng Hu, Jing Wang, Bo Hu, Ling Lu, Qiang Xuan, Yuan Han Qin. Increased urinary C-type natriuretic peptide excretion may be an early marker of renal tubulointerstitial fibrosis.
Peptides.
2012 Sep; 37(1):98-105. doi:
10.1016/j.peptides.2012.06.009. [PMID: 22743139] - Alsayed Ahmed Alnahal, Usama Ahmed Khalil, Magada Alsayed Diab, Ali Fahmy Zanaty. Expression of angiotensin-converting enzyme mRNA gene in the kidneys of patients with glomerulonephrites.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2012 Sep; 23(5):993-9. doi:
10.4103/1319-2442.100881. [PMID: 22982912] - Y F Jiang, B He, J Ma, N-P Li, G-Z Gong, D Cheng. Comparison of the antiviral effects of entecavir and adefovir dipivoxil in chronic HBV infection: a randomized control trial.
Acta gastro-enterologica Belgica.
2012 Sep; 75(3):316-21. doi:
NULL. [PMID: 23082701] - Kubra Kaynar, Safak Ersoz, Rezzan Aliyazicioglu, Aysegul Uzun, Sukru Ulusoy, Sait Al, Gulsum Ozkan, Muammer Cansız. Is there any way to protect from tacrolimus-induced renal and pancreas injury?.
Clinical transplantation.
2012 Sep; 26(5):722-8. doi:
10.1111/j.1399-0012.2012.01603.x. [PMID: 22428934] - Yun-Wei Shi, Cai-Ping Wang, Lei Liu, Yang-Liu Liu, Xing Wang, Ye Hong, Zhen Li, Ling-Dong Kong. Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.
Molecular nutrition & food research.
2012 Sep; 56(9):1433-44. doi:
10.1002/mnfr.201100828. [PMID: 22865646] - Farzaneh Ashrafi, Sara Haghshenas, Mehdi Nematbakhsh, Hamid Nasri, Ardeshir Talebi, Fatemeh Eshraghi-Jazi, Zahra Pezeshki, Tahereh Safari. The Role of Magnesium Supplementation in Cisplatin-induced Nephrotoxicity in a Rat Model: No Nephroprotectant Effect.
International journal of preventive medicine.
2012 Sep; 3(9):637-43. doi:
NULL. [PMID: 23024853] - Rieko Katayama, Jun Saito, Masaaki Katayama, Norio Yamagishi, Tetsuro Yamashita, Masaki Kato, Kazuhisa Furuhama. Simplified procedure for the estimation of glomerular filtration rate following intravenous administration of iodixanol in cats.
American journal of veterinary research.
2012 Sep; 73(9):1344-9. doi:
10.2460/ajvr.73.9.1344. [PMID: 22924714] - Qin Zhang, Gonçalo Gamboa da Costa, Linda S Von Tungeln, Cristina C Jacob, Ronald P Brown, Peter L Goering. Urinary biomarker detection of melamine- and cyanuric acid-induced kidney injury in rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2012 Sep; 129(1):1-8. doi:
10.1093/toxsci/kfs182. [PMID: 22610612] - Chia-Hung Yen, Kun-Chen Lin, Steve Leu, Cheuk-Kwan Sun, Li-Teh Chang, Han-Tan Chai, Sheng-Ying Chung, Hsueh-Wen Chang, Sheung-Fat Ko, Yen-Ta Chen, Hon-Kan Yip. Chronic exposure to environmental contaminant nonylphenol exacerbates adenine-induced chronic renal insufficiency: role of signaling pathways and therapeutic impact of rosuvastatin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2012 Aug; 46(5):455-67. doi:
10.1016/j.ejps.2012.03.009. [PMID: 22484332] - Gaoming Wang, Hairong Huang, Haiwei Wu, Chen Wu, Yanhui Xu, Lian Wang, Xiaolong Liu, Changtian Wang, Yi Shen, Demin Li, Hua Jing. Erythropoietin attenuates cardiopulmonary bypass-induced renal inflammatory injury by inhibiting nuclear factor-κB p65 expression.
European journal of pharmacology.
2012 Aug; 689(1-3):154-9. doi:
10.1016/j.ejphar.2012.05.027. [PMID: 22659586] - Yi Li, Xi Tang, Juqian Zhang, Taixiang Wu. Nutritional support for acute kidney injury.
The Cochrane database of systematic reviews.
2012 Aug; ?(8):CD005426. doi:
10.1002/14651858.cd005426.pub3. [PMID: 22895948] - Ho-Jeong Lee, Hyun-Kyung Yu, Jin-Hyung Ahn, Yong-Keun Park, Yeup Yoon, Jang-Seong Kim, Sun-Jin Kim. Repeated intravenous infusion of human apolipoprotein(a) kringle V is associated with reversible dose-dependent acute tubulointerstitial nephritis without affecting glomerular filtration function.
Toxicology letters.
2012 Aug; 212(3):298-306. doi:
10.1016/j.toxlet.2012.05.019. [PMID: 22659101] - Hiroyuki Terawaki, Yukie Matsuyama, Nanae Matsuo, Makoto Ogura, Jun Mitome, Akihiko Hamaguchi, Tomoyoshi Terada, Seiichi Era, Tatsuo Hosoya. A lower level of reduced albumin induces serious cardiovascular incidence among peritoneal dialysis patients.
Clinical and experimental nephrology.
2012 Aug; 16(4):629-35. doi:
10.1007/s10157-012-0610-x. [PMID: 22358613] - Seung-Min Lee, Yoonsu Cho, Hye-Kyung Chung, Dong-Hyuk Shin, Woel-Kyu Ha, Sang-Chul Lee, Min-Jeong Shin. Effects of kimchi supplementation on blood pressure and cardiac hypertrophy with varying sodium content in spontaneously hypertensive rats.
Nutrition research and practice.
2012 Aug; 6(4):315-21. doi:
10.4162/nrp.2012.6.4.315. [PMID: 22977685] - Wen-Hung Huang, Cheng-Chieh Hung, Chih-Wei Yang, Jeng-Yi Huang. High correlation between clearance of renal protein-bound uremic toxins (indoxyl sulfate and p-cresyl sulfate) and renal water-soluble toxins in peritoneal dialysis patients.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2012 Aug; 16(4):361-7. doi:
10.1111/j.1744-9987.2012.01068.x. [PMID: 22817125] - Caitlin C O'Meara, Matthew Hoffman, William E Sweeney, Shirng-Wern Tsaih, Bing Xiao, Howard J Jacob, Ellis D Avner, Carol Moreno. Role of genetic modifiers in an orthologous rat model of ARPKD.
Physiological genomics.
2012 Aug; 44(15):741-53. doi:
10.1152/physiolgenomics.00187.2011. [PMID: 22669842]