N-ethylmaleimide (BioDeep_00000003450)
Secondary id: BioDeep_00001867788
human metabolite blood metabolite
代谢物信息卡片
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
化学式: C6H7NO2 (125.0477)
中文名称: N-乙基顺丁烯二酰亚胺, N-乙基马来酰亚胺
谱图信息:
最多检出来源 Homo sapiens(blood) 25.49%
分子结构信息
SMILES: CCn(c(=O)1)c(=O)cc1
InChI: InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D013439 - Sulfhydryl Reagents
D004791 - Enzyme Inhibitors
KEIO_ID E008
同义名列表
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:44485
- KEGG: C02441
- PubChem: 4362
- HMDB: HMDB0255137
- Metlin: METLIN65769
- DrugBank: DB02967
- ChEMBL: CHEMBL8211
- Wikipedia: N-Ethylmaleimide
- MeSH: Ethylmaleimide
- MetaCyc: N-ETHYLMALEIMIDE
- CAS: 25668-22-8
- CAS: 128-53-0
- MoNA: KO002831
- MoNA: KO002832
- MoNA: KO002830
- MoNA: KO002833
- PMhub: MS000009696
- PubChem: 5463
- PDB-CCD: NEQ
- NIKKAJI: J21.254G
- RefMet: N-Ethylmaleimide
- KNApSAcK: 44485
分类词条
相关代谢途径
Reactome(0)
BioCyc(97)
- alkylnitronates degradation
- O-antigen building blocks biosynthesis (E. coli)
- superpathway of b heme biosynthesis from glycine
- superpathway of L-phenylalanine biosynthesis
- anaerobic energy metabolism (invertebrates, mitochondrial)
- superpathway of anaerobic energy metabolism (invertebrates)
- superpathway of demethylmenaquinol-8 biosynthesis I
- superpathway of L-methionine biosynthesis (transsulfuration)
- superpathway of L-homoserine and L-methionine biosynthesis
- superpathway of hexitol degradation (bacteria)
- D-sorbitol degradation II
- UDP-N-acetyl-D-glucosamine biosynthesis I
- lupanine biosynthesis
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
- superpathway of aromatic amino acid biosynthesis
- superpathway of bacteriochlorophyll a biosynthesis
- 2-carboxy-1,4-naphthoquinol biosynthesis
- superpathway of menaquinol-8 biosynthesis I
- superpathway of chorismate metabolism
- gallate degradation III (anaerobic)
- aspartate superpathway
- superpathway of S-adenosyl-L-methionine biosynthesis
- salvianin biosynthesis
- pelargonidin conjugates biosynthesis
- superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)
- shisonin biosynthesis
- superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)
- superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis
- tetrapyrrole biosynthesis II (from glycine)
- heme b biosynthesis I (aerobic)
- protocatechuate degradation I (meta-cleavage pathway)
- trans-4-hydroxy-L-proline degradation II
- indolmycin biosynthesis
- L-lysine biosynthesis I
- canavanine degradation
- superpathway of polyamine biosynthesis I
- superpathway of arginine and polyamine biosynthesis
- superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation
- superpathway of L-arginine and L-ornithine degradation
- formaldehyde oxidation II (glutathione-dependent)
- aurone biosynthesis
- polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)
- polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)
- aflatoxins B1 and G1 biosynthesis
- kaempferide triglycoside biosynthesis
- superpathway of polymethylated quercetin/quercetagetin glucoside biosynthesis (Chrysosplenium)
- anhydromuropeptides recycling I
- formate oxidation to CO2
- curcumin degradation
- superpathway of microbial D-galacturonate and D-glucuronate degradation
- D-carnitine degradation I
- nicotinate degradation I
- L-valine degradation I
- superpathway of CMP-sialic acids biosynthesis
- glycocholate metabolism (bacteria)
- L-arginine degradation V (arginine deiminase pathway)
- superpathway of glycerol degradation to 1,3-propanediol
- 3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)
- superpathway of L-lysine degradation
- L-lysine fermentation to acetate and butanoate
- bile acids degradation
- 1,2-dichloroethane degradation
- spermidine biosynthesis I
- L-phenylalanine biosynthesis I
- eupatolitin 3-O-glucoside biosynthesis
- lactate biosynthesis (archaea)
- chitin derivatives degradation
- superpathway of ergosterol biosynthesis I
- superpathway of ergosterol biosynthesis
- CMP-N-acetylneuraminate biosynthesis I (eukaryotes)
- protein N-glycosylation initial phase (eukaryotic)
- diacylglycerol and triacylglycerol biosynthesis
- patchoulol biosynthesis
- methylgallate degradation
- 4-hydroxymandelate degradation
- 4-amino-3-hydroxybenzoate degradation
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate
- ferrichrome biosynthesis
- superpathway of aromatic compound degradation via 3-oxoadipate
- norspermidine biosynthesis
- superpathway of polyamine biosynthesis III
- superpathway of penicillin, cephalosporin and cephamycin biosynthesis
- deacetylcephalosporin C biosynthesis
- isopenicillin N biosynthesis
- glycerol degradation II
- violdelphin biosynthesis
- trans-4-hydroxy-L-proline degradation I
- superpathway of L-methionine salvage and degradation
- S-adenosyl-L-methionine cycle II
- protein N-glycosylation (eukaryotic) initial steps
- pyruvate to cytochrome bo oxidase electron transfer
- methylglyoxal degradation VI
- sophorosyloxydocosanoate deacetylation
- L-homoserine biosynthesis
- superpathway of L-threonine biosynthesis
- cyclopropane fatty acid (CFA) biosynthesis
- superpathway of L-isoleucine biosynthesis I
PlantCyc(15)
- superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)
- salvianin biosynthesis
- shisonin biosynthesis
- pelargonidin conjugates biosynthesis
- lupanine biosynthesis
- superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)
- canavanine degradation
- aurone biosynthesis
- polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)
- polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)
- kaempferide triglycoside biosynthesis
- superpathway of polymethylated quercetin/quercetagetin glucoside biosynthesis (Chrysosplenium)
- eupatolitin 3-O-glucoside biosynthesis
- violdelphin biosynthesis
- S-adenosyl-L-methionine cycle II
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Li Zhang, Quan Yuan, Chaoyang Hu, Xue Sun, Yifu Gong, Nianjun Xu. Characterization of monogalactosyldiacylglycerol synthases in Gracilariopsis lemaneiformis and their potential roles in the fading of the thallus.
Journal of phycology.
2023 12; 59(6):1258-1271. doi:
10.1111/jpy.13384. [PMID: 37688517] - Ruiling Li, Na Wu, Hui Xue, Binghong Gao, Huilan Liu, Tianfeng Han, Xiaobo Hu, Yonggang Tu, Yan Zhao. Influence and effect mechanism of disulfide bonds linkages between protein-coated lipid droplets and the protein matrix on the physicochemical properties, microstructure, and protein structure of ovalbumin emulsion gels.
Colloids and surfaces. B, Biointerfaces.
2023 Jan; 223(?):113182. doi:
10.1016/j.colsurfb.2023.113182. [PMID: 36736177] - Norin Chaudhry, Margaux Sica, Satya Surabhi, David Sanchez Hernandez, Ana Mesquita, Adem Selimovic, Ayesha Riaz, Laury Lescat, Hua Bai, Gustavo C MacIntosh, Andreas Jenny. Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila.
Autophagy.
2022 Oct; 18(10):2443-2458. doi:
10.1080/15548627.2022.2038999. [PMID: 35266854] - Yeshveer Singh, Ruby Sharma, Manasi Mishra, Praveen Kumar Verma, Ajay Kumar Saxena. Crystal structure of ArOYE6 reveals a novel C-terminal helical extension and mechanistic insights into the distinct class III OYEs from pathogenic fungi.
The FEBS journal.
2022 09; 289(18):5531-5550. doi:
10.1111/febs.16445. [PMID: 35313092] - Laiza S Biano, Alan S Oliveira, David N Palmeira, Luis André Silva, Ricardo L C de Albuquerque-Junior, Marcelo C Duarte, Cristiane B Correa, Renata Grespan, Josemar S Batista, Enilton A Camargo. Gastroprotective action of the ethanol extract of Leonurus sibiricus L. (Lamiaceae) in mice.
Journal of ethnopharmacology.
2022 Feb; 284(?):114792. doi:
10.1016/j.jep.2021.114792. [PMID: 34737011] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Ruihua Xie, Yaqian Li, Zile Zhou, Xiao Pang, Cuiyan Wu, Peng Yin, Haitao Li. A near-infrared excitation/emission fluorescent probe for imaging of endogenous cysteine in living cells and zebrafish.
Analytical and bioanalytical chemistry.
2020 Sep; 412(23):5539-5550. doi:
10.1007/s00216-020-02812-4. [PMID: 32681222] - Surasa Nagachinta, Guillaume Becker, Sylvestre Dammicco, Maria Elisa Serrano, Natacha Leroi, Mohamed Ali Bahri, Alain Plenevaux, Christian Lemaire, Rafael Lopez, André Luxen, Maria de la Fuente. Radiolabelling of lipid-based nanocarriers with fluorine-18 for in vivo tracking by PET.
Colloids and surfaces. B, Biointerfaces.
2020 Apr; 188(?):110793. doi:
10.1016/j.colsurfb.2020.110793. [PMID: 31982792] - Yan Qin, Jialong Fan, Wei Yang, Bingbing Shen, Yupei Yang, Qi Zhou, Wenming Chen, Muhammad Daniyal, Feng Xiao, Wen-Bing Sheng, Huanghe Yu, Jiantao Zhou, Wei Wang, Chunyi Tong, Bin Liu. Endogenous Cys-Assisted GSH@AgNCs-rGO Nanoprobe for Real-Time Monitoring of Dynamic Change in GSH Levels Regulated by Natural Drug.
Analytical chemistry.
2020 01; 92(2):1988-1996. doi:
10.1021/acs.analchem.9b04374. [PMID: 31802668] - George W Preston, Liping Yang, David H Phillips, Claudia S Maier. Visualisation tools for dependent peptide searches to support the exploration of in vitro protein modifications.
PloS one.
2020; 15(7):e0235263. doi:
10.1371/journal.pone.0235263. [PMID: 32639981] - Joanna Podkalicka, Cedric M Blouin. GPMVs as a Tool to Study Caveolin-Interacting Partners.
Methods in molecular biology (Clifton, N.J.).
2020; 2169(?):81-88. doi:
10.1007/978-1-0716-0732-9_8. [PMID: 32548821] - Wen Zheng, Dongjun Shen, Yadi Pan, Danyang Yi, Yijuan Long, Huzhi Zheng. Enhancing the peroxidase-like activity of ficin by rational blocking thiol groups for colorimetric detection of biothiols.
Talanta.
2019 Nov; 204(?):833-839. doi:
10.1016/j.talanta.2019.06.073. [PMID: 31357372] - Zhenyu Yao, Yanmin Zhang, Lawrence A Potempa, Ibraheem Rajab, Lianxing Ji, Jianmin Lv, Shanhui Liu, Lin Zhang, Haibin Wu. A redox sensitivity-based method to quantify both pentameric and monomeric C-reactive protein in a single assay.
Journal of immunological methods.
2019 07; 470(?):40-45. doi:
10.1016/j.jim.2019.04.009. [PMID: 31034879] - Edwige Berthelot, Jean-Luc Macia, Alexandre Martinière, Alexandre Morisset, Romain Gallet, Stéphane Blanc, Mounia Khelifa, Martin Drucker. Pharmacological analysis of transmission activation of two aphid-vectored plant viruses, turnip mosaic virus and cauliflower mosaic virus.
Scientific reports.
2019 06; 9(1):9374. doi:
10.1038/s41598-019-45904-7. [PMID: 31253881] - María Elena Sánchez-Mendoza, Yaraset López-Lorenzo, Leticia Cruz-Antonio, Audifás-Salvador Matus-Meza, Yolanda Sánchez-Mendoza, Jesús Arrieta. Gastroprotection of Calein D against Ethanol-Induced Gastric Lesions in Mice: Role of Prostaglandins, Nitric Oxide and Sulfhydryls.
Molecules (Basel, Switzerland).
2019 Feb; 24(3):. doi:
10.3390/molecules24030622. [PMID: 30754621] - Faviola Tavares-Carreón, Xiang Ruan, Amy Ford, Miguel A Valvano. Sulfhydryl Labeling as a Tool to Investigate the Topology of Membrane Proteins Involved in Lipopolysaccharide Biosynthesis.
Methods in molecular biology (Clifton, N.J.).
2019; 1954(?):203-213. doi:
10.1007/978-1-4939-9154-9_16. [PMID: 30864134] - Derell Hardman, Daniel McFalls, Stylianos Fakas. Characterization of phosphatidic acid phosphatase activity in the oleaginous yeast Yarrowia lipolytica and its role in lipid biosynthesis.
Yeast (Chichester, England).
2017 02; 34(2):83-91. doi:
10.1002/yea.3216. [PMID: 27743491] - Charlotte H Hurst, Dionne Turnbull, Fiona Plain, William Fuller, Piers A Hemsley. Maleimide scavenging enhances determination of protein S-palmitoylation state in acyl-exchange methods.
BioTechniques.
2017 02; 62(2):69-75. doi:
10.2144/000114516. [PMID: 28193150] - Mohammad Azam Mansoor, Dag Olav Andersen. In vivo effect of N-ethylmaleimide (NEM) on the measurement of nitrate in plasma.
Clinical biochemistry.
2016 Dec; 49(18):1361-1363. doi:
10.1016/j.clinbiochem.2016.07.006. [PMID: 27432156] - Sisse Jongberg, Marianne N Lund, David I Pattison, Leif H Skibsted, Michael J Davies. Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components.
Food chemistry.
2016 May; 199(?):36-41. doi:
10.1016/j.foodchem.2015.11.120. [PMID: 26775941] - Paulrayer Antonisamy, Mariadhas Valan Arasu, Muniappan Dhanasekaran, Ki Choon Choi, Adithan Aravinthan, Nam Soo Kim, Chang-Won Kang, Jong-Hoon Kim. Protective effects of trigonelline against indomethacin-induced gastric ulcer in rats and potential underlying mechanisms.
Food & function.
2016 Jan; 7(1):398-408. doi:
10.1039/c5fo00403a. [PMID: 26499137] - Michalis Petropoulos, Georgia Karamolegkou, Eleftheria Rosmaraki, Sotiris Tsakas. Hydrogen peroxide signals E. coli phagocytosis by human polymorphonuclear cells; up-stream and down-stream pathway.
Redox biology.
2015 Dec; 6(?):100-105. doi:
10.1016/j.redox.2015.07.004. [PMID: 26204503] - Masashi Morita, Misato Kawamichi, Yusuke Shimura, Kosuke Kawaguchi, Shiro Watanabe, Tsuneo Imanaka. Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase.
Metabolic brain disease.
2015 Dec; 30(6):1359-67. doi:
10.1007/s11011-015-9701-1. [PMID: 26108493] - Caroline Donzeli Pereira, Naoto Minamino, Toshifumi Takao. Free Thiol of Transthyretin in Human Plasma Most Accessible to Modification/Oxidation.
Analytical chemistry.
2015 Nov; 87(21):10785-91. doi:
10.1021/acs.analchem.5b03431. [PMID: 26441309] - Teresa Parra, Julio Benites, Lina M Ruiz, Beatriz Sepulveda, Mario Simirgiotis, Carlos Areche. Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls.
Bioorganic & medicinal chemistry letters.
2015 Jul; 25(14):2813-7. doi:
10.1016/j.bmcl.2015.04.095. [PMID: 26009162] - Ellen L Berg, Mark A Polokoff, Alison O'Mahony, Dat Nguyen, Xitong Li. Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.
International journal of molecular sciences.
2015 Jan; 16(1):1008-29. doi:
10.3390/ijms16011008. [PMID: 25569083] - A A Kaplia. [The influence of iron ions on ATP-hydrolases activity of cell membranes of rat colon smooth muscle and kidney].
Ukrainian biochemical journal.
2015 Jan; 87(1):83-90. doi:
10.15407/ubj87.01.083. [PMID: 26036134] - Saeeda-S Almarzooqi, Ali-S Alfazari, Hidaya-M Abdul-Kader, Dhanya Saraswathiamma, Alia-S Albawardi, Abdul-Kader Souid. In vitro effects of platinum compounds on renal cellular respiration in mice.
International journal of clinical and experimental pathology.
2015; 8(1):81-95. doi:
. [PMID: 25755695] - Mitchell R Mcgill, Hartmut Jaeschke. A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimide.
Toxicology mechanisms and methods.
2015; 25(8):589-95. doi:
10.3109/15376516.2015.1094844. [PMID: 26461121] - Carlos Areche, Beatriz Sepulveda, Aurelio San Martin, Olimpo Garcia-Beltrán, Mario Simirgiotis, Alvaro Cañete. An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers.
Organic & biomolecular chemistry.
2014 Sep; 12(33):6406-13. doi:
10.1039/c4ob00966e. [PMID: 25008488] - Long Yuan, Wenying Jian, Duxi Zhang, Anne-Françoise Aubry, Mark E Arnold. Application of a stabilizer cocktail of N-ethylmaleimide and phenylmethanesulfonyl fluoride to concurrently stabilize the disulfide and ester containing compounds in a plasma LC-MS/MS assay.
Journal of pharmaceutical and biomedical analysis.
2014 Jan; 88(?):552-61. doi:
10.1016/j.jpba.2013.10.014. [PMID: 24211707] - Damien Thiry, Remy Francq, Damien Cossement, David Guerin, Dominique Vuillaume, Rony Snyders. Establishment of a derivatization method to quantify thiol function in sulfur-containing plasma polymer films.
Langmuir : the ACS journal of surfaces and colloids.
2013 Oct; 29(43):13183-9. doi:
10.1021/la402891t. [PMID: 24066612] - Sarah R Beyer, Robert T Mallmann, Isabel Jaenecke, Alice Habermeier, Jean-Paul Boissel, Ellen I Closs. Identification of cysteine residues in human cationic amino acid transporter hCAT-2A that are targets for inhibition by N-ethylmaleimide.
The Journal of biological chemistry.
2013 Oct; 288(42):30411-30419. doi:
10.1074/jbc.m113.490698. [PMID: 24019517] - Daniela Giustarini, Isabella Dalle-Donne, Aldo Milzani, Paolo Fanti, Ranieri Rossi. Analysis of GSH and GSSG after derivatization with N-ethylmaleimide.
Nature protocols.
2013 Sep; 8(9):1660-9. doi:
10.1038/nprot.2013.095. [PMID: 23928499] - Quansheng Zhu, Xuesi M Shao, Liyo Kao, Rustam Azimov, Alan M Weinstein, Debra Newman, Weixin Liu, Ira Kurtz. Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis.
American journal of physiology. Cell physiology.
2013 Aug; 305(4):C392-405. doi:
10.1152/ajpcell.00044.2013. [PMID: 23636456] - Birger Wenge, Heinz Bönisch. The role of cysteines and histidins of the norepinephrine transporter.
Neurochemical research.
2013 Jul; 38(7):1303-14. doi:
10.1007/s11064-013-1022-3. [PMID: 23525969] - Sadamu Kurono, Yuka Kaneko, Satomi Niwayama. Quantitative protein analysis using (13)C7-labeled iodoacetanilide and d5-labeled N-ethylmaleimide by nano liquid chromatography/nanoelectrospray ionization ion trap mass spectrometry.
Bioorganic & medicinal chemistry letters.
2013 May; 23(10):3111-8. doi:
10.1016/j.bmcl.2013.02.112. [PMID: 23562245] - Ljiljana Menckhoff, Nicole Mielke-Ehret, Friedrich Buck, Mirjana Vuletić, Sabine Lüthje. Plasma membrane-associated malate dehydrogenase of maize (Zea mays L.) roots: native versus recombinant protein.
Journal of proteomics.
2013 Mar; 80(?):66-77. doi:
10.1016/j.jprot.2012.12.015. [PMID: 23313174] - Yi-Ting Wang, Der-Wan Tzeng, Chun-Yu Wang, Jing-Yin Hong, Jia-Ling Yang. APE1/Ref-1 prevents oxidative inactivation of ERK for G1-to-S progression following lead acetate exposure.
Toxicology.
2013 Mar; 305(?):120-9. doi:
10.1016/j.tox.2013.01.010. [PMID: 23370007] - Assaf Ben-Yona, Baruch I Kanner. Functional defects in the external and internal thin gates of the γ-aminobutyric acid (GABA) transporter GAT-1 can compensate each other.
The Journal of biological chemistry.
2013 Feb; 288(7):4549-56. doi:
10.1074/jbc.m112.430215. [PMID: 23288838] - Zeynab Shahmoradi, Fatemeh Tamaskani, Hamid Reza Sadeghipour, Ahmad Abdolzadeh. Redox changes accompanying storage protein mobilization in moist chilled and warm incubated walnut kernels prior to germination.
Journal of plant physiology.
2013 Jan; 170(1):6-17. doi:
10.1016/j.jplph.2012.08.014. [PMID: 22989946] - Agathe Courteille, Simona Vesa, Ruth Sanz-Barrio, Anne-Claire Cazalé, Noëlle Becuwe-Linka, Immaculada Farran, Michel Havaux, Pascal Rey, Dominique Rumeau. Thioredoxin m4 controls photosynthetic alternative electron pathways in Arabidopsis.
Plant physiology.
2013 Jan; 161(1):508-20. doi:
10.1104/pp.112.207019. [PMID: 23151348] - Jaison J Omoto, Matthew J Maestas, Ali Rahnama-Vaghef, Ye E Choi, Gerardo Salto, Rachel V Sanchez, Cynthia M Anderson, Sepehr Eskandari. Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue.
The Journal of membrane biology.
2012 Dec; 245(12):841-57. doi:
10.1007/s00232-012-9492-9. [PMID: 22918627] - Tsuneo Hakoyama, Ryo Oi, Kazuya Hazuma, Eri Suga, Yuka Adachi, Mayumi Kobayashi, Rie Akai, Shusei Sato, Eigo Fukai, Satoshi Tabata, Satoshi Shibata, Guo-Jiang Wu, Yoshihiro Hase, Atsushi Tanaka, Masayoshi Kawaguchi, Hiroshi Kouchi, Yosuke Umehara, Norio Suganuma. The SNARE protein SYP71 expressed in vascular tissues is involved in symbiotic nitrogen fixation in Lotus japonicus nodules.
Plant physiology.
2012 Oct; 160(2):897-905. doi:
10.1104/pp.112.200782. [PMID: 22858633] - Subhankar Dolai, Tao Liang, Patrick P L Lam, Nestor A Fernandez, Subbulaksmi Chidambaram, Herbert Y Gaisano. Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats.
Gastroenterology.
2012 Sep; 143(3):832-843.e7. doi:
10.1053/j.gastro.2012.06.011. [PMID: 22710192] - Yasuhito Ohsaka, Hoyoku Nishino. Cooling-increased phospho-β-arrestin-1 and β-arrestin-1 expression levels in 3T3-L1 adipocytes.
Cryobiology.
2012 Aug; 65(1):12-20. doi:
10.1016/j.cryobiol.2012.03.001. [PMID: 22465333] - Carlos Vera-Arzave, Leticia Cruz Antonio, Jesús Arrieta, Gerardo Cruz-Hernández, Antonio Magdiel Velasquez-Mendez, Adelfo Reyes-Ramírez, María Elena Sánchez-Mendoza. Gastroprotection of suaveolol, isolated from Hyptis suaveolens, against ethanol-induced gastric lesions in Wistar rats: role of prostaglandins, nitric oxide and sulfhydryls.
Molecules (Basel, Switzerland).
2012 Jul; 17(8):8917-27. doi:
10.3390/molecules17088917. [PMID: 22836211] - James R Springstead, B Gabriel Gugiu, Sangderk Lee, Seung Cha, Andrew D Watson, Judith A Berliner. Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function.
Journal of lipid research.
2012 Jul; 53(7):1304-15. doi:
10.1194/jlr.m025320. [PMID: 22550136] - Erfan Nur, Dees P Brandjes, Tom Teerlink, Hans-Martin Otten, Ronald P J Oude Elferink, Frits Muskiet, Ludo M Evers, Hugo ten Cate, Bart J Biemond, Ashley J Duits, John-John B Schnog. N-acetylcysteine reduces oxidative stress in sickle cell patients.
Annals of hematology.
2012 Jul; 91(7):1097-105. doi:
10.1007/s00277-011-1404-z. [PMID: 22318468] - Katja Heinig, Franz Bucheli, Olaf Kuhlmann, Manfred Zell, Axel Pähler, Elke Zwanziger, Günter Gross, Joseph Tardio, Tomohiro Ishikawa, Tomoko Yamashita. Determination of dalcetrapib by liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2012 Jul; 66(?):314-24. doi:
10.1016/j.jpba.2012.03.056. [PMID: 22541249] - W L Boatright, Q Lei, M S Jahan. Effect of moisture, lipids, and select amino acid blocking agents on the formation and stability of metastable radicals in powdered soy proteins.
Journal of food science.
2012 Jun; 77(6):C620-6. doi:
10.1111/j.1750-3841.2012.02722.x. [PMID: 22625876] - Yasemin D Akcay, Ferhan G Sagin, Kenan Aksu, Gokhan Keser, Emma Taylor, Iona Knight, Paul G Winyard, Eser Y Sozmen. A panel of oxidative stress assays does not provide supplementary diagnostic information in Behcet's disease patients.
Journal of inflammation (London, England).
2012 Apr; 9(?):13. doi:
10.1186/1476-9255-9-13. [PMID: 22472022] - Li Yuan, Lijun Wang, Zujing Han, Yuanzhong Jiang, Lili Zhao, Hong Liu, Li Yang, Keming Luo. Molecular cloning and characterization of PtrLAR3, a gene encoding leucoanthocyanidin reductase from Populus trichocarpa, and its constitutive expression enhances fungal resistance in transgenic plants.
Journal of experimental botany.
2012 Apr; 63(7):2513-24. doi:
10.1093/jxb/err425. [PMID: 22268151] - Ana Beatriz Albino de Almeida, Anderson Luiz-Ferreira, Maíra Cola, Luciana Di Pietro Magri, Leonia Maria Batista, Joseilson Alves de Paiva, José Roberto Trigo, Alba R M Souza-Brito. Anti-ulcerogenic mechanisms of the sesquiterpene lactone onopordopicrin-enriched fraction from Arctium lappa L. (Asteraceae): role of somatostatin, gastrin, and endogenous sulfhydryls and nitric oxide.
Journal of medicinal food.
2012 Apr; 15(4):378-83. doi:
10.1089/jmf.2011.0025. [PMID: 22191571] - Kenjiro Tanaka, Takahiro Shimizu, Lianyi Lu, Kunihiko Yokotani. Possible involvement of S-nitrosylation of brain cyclooxygenase-1 in bombesin-induced central activation of adrenomedullary outflow in rats.
European journal of pharmacology.
2012 Mar; 679(1-3):40-50. doi:
10.1016/j.ejphar.2012.01.005. [PMID: 22293370] - Tetsuro Ishii, Eiji Warabi, Toru Yanagawa. Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.
Journal of clinical biochemistry and nutrition.
2012 Mar; 50(2):91-105. doi:
10.3164/jcbn.11-109. [PMID: 22448089] - Irina Akopova, Sabina Tatur, Mariusz Grygorczyk, Rafał Luchowski, Ignacy Gryczynski, Zygmunt Gryczynski, Julian Borejdo, Ryszard Grygorczyk. Imaging exocytosis of ATP-containing vesicles with TIRF microscopy in lung epithelial A549 cells.
Purinergic signalling.
2012 Mar; 8(1):59-70. doi:
10.1007/s11302-011-9259-2. [PMID: 21881960] - Patrick M Dansette, Julien Rosi, Gildas Bertho, Daniel Mansuy. Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer.
Chemical research in toxicology.
2012 Feb; 25(2):348-56. doi:
10.1021/tx2004085. [PMID: 22103858] - Ojikumar Lukram, Mukund Zarapkar, Chandan Kumar Jha, Shivaji Parmar, Keshav S Tomar, Amit Hande. Electrospray ionization LC-MS/MS validated method for the determination of the active metabolite (R-138727) of prasugrel in human plasma and its application to a bioequivalence study.
Drug testing and analysis.
2012 Feb; 4(2):158-66. doi:
10.1002/dta.264. [PMID: 21438161] - Andria P Medina, Jialing Lin, Paul H Weigel. Hyaluronan synthase mediates dye translocation across liposomal membranes.
BMC biochemistry.
2012 Jan; 13(?):2. doi:
10.1186/1471-2091-13-2. [PMID: 22276637] - Idinath Badirou, Mohamad Kurdi, Paulette Legendre, Julie Rayes, Marijke Bryckaert, Caterina Casari, Peter J Lenting, Olivier D Christophe, Cecile V Denis. In vivo analysis of the role of O-glycosylations of von Willebrand factor.
PloS one.
2012; 7(5):e37508. doi:
10.1371/journal.pone.0037508. [PMID: 22616016] - Pin-Kuei Fu, Chieh-Liang Wu, Tung-Hu Tsai, Ching-Liang Hsieh. Anti-inflammatory and anticoagulative effects of paeonol on LPS-induced acute lung injury in rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):837513. doi:
10.1155/2012/837513. [PMID: 22454687] - Lianzhen Li, Xiaoli Liu, Willie J G M Peijnenburg, Jianmin Zhao, Xiaobing Chen, Junbao Yu, Huifeng Wu. Pathways of cadmium fluxes in the root of the halophyte Suaeda salsa.
Ecotoxicology and environmental safety.
2012 Jan; 75(1):1-7. doi:
10.1016/j.ecoenv.2011.09.007. [PMID: 21943551] - A V Ivanov, B P Luzyanin, A A Kubatiev. The use of N-ethylmaleimide for mass spectrometric detection of homocysteine fractions in blood plasma.
Bulletin of experimental biology and medicine.
2012 Jan; 152(3):289-92. doi:
10.1007/s10517-012-1510-5. [PMID: 22803068] - Weiwei Huang, Tiantian He, Chengsen Chai, Yuan Yang, Yahong Zheng, Pei Zhou, Xiaoxia Qiao, Bin Zhang, Zengzhen Liu, Junru Wang, Changhong Shi, Liping Lei, Kun Gao, Hewei Li, Sue Zhong, Libo Yao, Meng-Er Huang, Ming Lei. Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression.
PloS one.
2012; 7(5):e37693. doi:
10.1371/journal.pone.0037693. [PMID: 22666381] - Christian Löw, Caroline Jegerschöld, Michael Kovermann, Per Moberg, Pär Nordlund. Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1.
PloS one.
2012; 7(6):e38244. doi:
10.1371/journal.pone.0038244. [PMID: 22675529] - Elena A Matveeva, Verda A Davis, Sidney W Whiteheart, Thomas C Vanaman, Greg A Gerhardt, John T Slevin. Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release.
Epilepsia.
2012 Jan; 53(1):157-67. doi:
10.1111/j.1528-1167.2011.03345.x. [PMID: 22150629] - Brijesh Kumar Singh, Madhulika Tripathi, Bhushan P Chaudhari, Pramod K Pandey, Poonam Kakkar. Natural terpenes prevent mitochondrial dysfunction, oxidative stress and release of apoptotic proteins during nimesulide-hepatotoxicity in rats.
PloS one.
2012; 7(4):e34200. doi:
10.1371/journal.pone.0034200. [PMID: 22509279] - Hai Wang, Shengbing Wang, Yuqing Lu, Sophie Alvarez, Leslie M Hicks, Xiaochun Ge, Yiji Xia. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis.
Journal of proteome research.
2012 Jan; 11(1):412-24. doi:
10.1021/pr200918f. [PMID: 22050424] - Naïm Bouazza, Jean-Marc Tréluyer, Chris Ottolenghi, Saik Urien, Georges Deschenes, Daniel Ricquier, Patrick Niaudet, Bernadette Chadefaux-Vekemans. Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients.
Orphanet journal of rare diseases.
2011 Dec; 6(?):86. doi:
10.1186/1750-1172-6-86. [PMID: 22195601] - Peter M Piermarini, Rebecca M Hine, Matthew Schepel, Jeremy Miyauchi, Klaus W Beyenbach. Role of an apical K,Cl cotransporter in urine formation by renal tubules of the yellow fever mosquito (Aedes aegypti).
American journal of physiology. Regulatory, integrative and comparative physiology.
2011 Nov; 301(5):R1318-37. doi:
10.1152/ajpregu.00223.2011. [PMID: 21813871] - Qiaoli Li, Michael Frank, Masashi Akiyama, Hiroshi Shimizu, Shiu-Ying Ho, Christine Thisse, Bernard Thisse, Eli Sprecher, Jouni Uitto. Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis.
Disease models & mechanisms.
2011 Nov; 4(6):777-85. doi:
10.1242/dmm.007146. [PMID: 21816950] - Valeria Menchise, Giuseppe Digilio, Eliana Gianolio, Evelina Cittadino, Valeria Catanzaro, Carla Carrera, Silvio Aime. In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent.
Molecular pharmaceutics.
2011 Oct; 8(5):1750-6. doi:
10.1021/mp2001044. [PMID: 21780833] - Anderson Luiz-Ferreira, Maira Cola, Victor Barbastefano, Elisangela Farias-Silva, Tamara Regina Calvo, Ana Beatriz Albino de Almeida, Claudia Helena Pellizzon, Clélia Akiko Hiruma-Lima, Wagner Vilegas, Alba Regina Monteiro Souza-Brito. Indigofera suffruticosa Mill as new source of healing agent: involvement of prostaglandin and mucus and heat shock proteins.
Journal of ethnopharmacology.
2011 Sep; 137(1):192-8. doi:
10.1016/j.jep.2011.05.006. [PMID: 21600972] - Kevin Moreau, Brinda Ravikumar, Maurizio Renna, Claudia Puri, David C Rubinsztein. Autophagosome precursor maturation requires homotypic fusion.
Cell.
2011 Jul; 146(2):303-17. doi:
10.1016/j.cell.2011.06.023. [PMID: 21784250] - Ilya Levental, Michal Grzybek, Kai Simons. Raft domains of variable properties and compositions in plasma membrane vesicles.
Proceedings of the National Academy of Sciences of the United States of America.
2011 Jul; 108(28):11411-6. doi:
10.1073/pnas.1105996108. [PMID: 21709267] - Mushfiquddin Khan, Harutoshi Sakakima, Tajinder S Dhammu, Anandakumar Shunmugavel, Yeong-Bin Im, Anne G Gilg, Avtar K Singh, Inderjit Singh. S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats.
Journal of neuroinflammation.
2011 Jul; 8(?):78. doi:
10.1186/1742-2094-8-78. [PMID: 21733162] - Mangang Wu, Youling L Xiong, Jie Chen. Role of disulphide linkages between protein-coated lipid droplets and the protein matrix in the rheological properties of porcine myofibrillar protein-peanut oil emulsion composite gels.
Meat science.
2011 Jul; 88(3):384-90. doi:
10.1016/j.meatsci.2011.01.014. [PMID: 21342749] - Christelle En Lin Chua, Bor Luen Tang. Rabs, SNAREs and α-synuclein--membrane trafficking defects in synucleinopathies.
Brain research reviews.
2011 Jun; 67(1-2):268-81. doi:
10.1016/j.brainresrev.2011.03.002. [PMID: 21439320] - Peter R Strege, Cheryl E Bernard, Robert E Kraichely, Amelia Mazzone, Lei Sha, Arthur Beyder, Simon J Gibbons, David R Linden, Michael L Kendrick, Michael G Sarr, Joseph H Szurszewski, Gianrico Farrugia. Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, Nav1.5.
American journal of physiology. Gastrointestinal and liver physiology.
2011 Jun; 300(6):G1105-14. doi:
10.1152/ajpgi.00556.2010. [PMID: 21393430] - Oussama El Far, Michael Seagar. A role for V-ATPase subunits in synaptic vesicle fusion?.
Journal of neurochemistry.
2011 May; 117(4):603-12. doi:
10.1111/j.1471-4159.2011.07234.x. [PMID: 21375531] - Bor Luen Tang, Heon Yung Gee, Min Goo Lee. The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome.
Traffic (Copenhagen, Denmark).
2011 Apr; 12(4):364-71. doi:
10.1111/j.1600-0854.2011.01161.x. [PMID: 21223469] - A V Ivanov, B P Luzianin, A A Moskovtsev, A S Rotkina, A A Kubatiev. [Determination of reduced homocysteine fraction in blood plasma with HPLC-MS].
Patologicheskaia fiziologiia i eksperimental'naia terapiia.
2011 Apr; ?(2):55-60. doi:
NULL. [PMID: 21846063] - Joris Wauman, Leentje De Ceuninck, Nele Vanderroost, Sam Lievens, Jan Tavernier. RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding.
Journal of cell science.
2011 Mar; 124(Pt 6):921-32. doi:
10.1242/jcs.078055. [PMID: 21378310] - Christin C T Chao, Anton Mihic, Robert G Tsushima, Herbert Y Gaisano. SNARE protein regulation of cardiac potassium channels and atrial natriuretic factor secretion.
Journal of molecular and cellular cardiology.
2011 Mar; 50(3):401-7. doi:
10.1016/j.yjmcc.2010.11.018. [PMID: 21129378] - Lisheng Peng, William H Tepp, Eric A Johnson, Min Dong. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
PLoS pathogens.
2011 Mar; 7(3):e1002008. doi:
10.1371/journal.ppat.1002008. [PMID: 21483489] - Xiao-Qing Dai, Greg Plummer, Marina Casimir, Youhou Kang, Catherine Hajmrle, Herbert Y Gaisano, Jocelyn E Manning Fox, Patrick E MacDonald. SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.
Diabetes.
2011 Mar; 60(3):838-47. doi:
10.2337/db10-0440. [PMID: 21266332] - Erin Tricker, Afsane Arvand, Raymond Kwan, Gordon Y Chen, Ewen Gallagher, Genhong Cheng. Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1.
PloS one.
2011 Feb; 6(2):e17310. doi:
10.1371/journal.pone.0017310. [PMID: 21364884] - Elita Avota, Erich Gulbins, Sibylle Schneider-Schaulies. DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells.
PLoS pathogens.
2011 Feb; 7(2):e1001290. doi:
10.1371/journal.ppat.1001290. [PMID: 21379338] - Weibing Yang, Sulin Ren, Xiaoming Zhang, Mingjun Gao, Shenghai Ye, Yongbin Qi, Yiyan Zheng, Juan Wang, Longjun Zeng, Qun Li, Shanjin Huang, Zuhua He. BENT UPPERMOST INTERNODE1 encodes the class II formin FH5 crucial for actin organization and rice development.
The Plant cell.
2011 Feb; 23(2):661-80. doi:
10.1105/tpc.110.081802. [PMID: 21307285] - María Elena Sánchez-Mendoza, Adelfo Reyes-Ramírez, Leticia Cruz Antonio, Luis Martínez Jiménez, Juan Rodríguez-Silverio, Jesús Arrieta. Bioassay-guided isolation of an anti-ulcer compound, tagitinin C, from Tithonia diversifolia: role of nitric oxide, prostaglandins and sulfhydryls.
Molecules (Basel, Switzerland).
2011 Jan; 16(1):665-74. doi:
10.3390/molecules16010665. [PMID: 21242945] - Shou-Wei Yin, Chuan-He Tang, Qi-Biao Wen, Xiao-Quan Yang. Conformational and thermal properties of phaseolin, the major storage protein of red kidney bean (Phaseolus vulgaris L.).
Journal of the science of food and agriculture.
2011 Jan; 91(1):94-9. doi:
10.1002/jsfa.4155. [PMID: 20815040] - Shou-Wei Yin, Chuan-He Tang, Xiao-Quan Yang, Qi-Biao Wen. Conformational study of red kidney bean (Phaseolus vulgaris L.) protein isolate (KPI) by tryptophan fluorescence and differential scanning calorimetry.
Journal of agricultural and food chemistry.
2011 Jan; 59(1):241-8. doi:
10.1021/jf1027608. [PMID: 21126074] - Norihiro Ryuman, Nobuo Watanabe, Takao Arai. S-nitrosation of cellular proteins by NO donors in rat embryonic fibroblast 3Y1 cells: factors affecting S-nitrosation.
Oxidative medicine and cellular longevity.
2011; 2011(?):450317. doi:
10.1155/2011/450317. [PMID: 21904643] - Shasha Gao, Tingyu Qin, Zhenzhen Liu, Maria Andrea Caceres, Carlos F Ronchi, C-Y Oliver Chen, Kyung-Jin Yeum, Allen Taylor, Jeffery B Blumberg, Yizhi Liu, Fu Shang. Lutein and zeaxanthin supplementation reduces H2O2-induced oxidative damage in human lens epithelial cells.
Molecular vision.
2011; 17(?):3180-90. doi:
. [PMID: 22194644] - Yi Xu, Alpay B Seven, Lijing Su, Qiu-Xing Jiang, Josep Rizo. Membrane bridging and hemifusion by denaturated Munc18.
PloS one.
2011; 6(7):e22012. doi:
10.1371/journal.pone.0022012. [PMID: 21765933] - Liang Zhang, Haiyan Zhang, Peng Liu, Huaiqing Hao, Jing Bo Jin, Jinxing Lin. Arabidopsis R-SNARE proteins VAMP721 and VAMP722 are required for cell plate formation.
PloS one.
2011; 6(10):e26129. doi:
10.1371/journal.pone.0026129. [PMID: 22022536] - Enika Nagababu, Joseph M Rifkind. Determination of s-nitrosothiols in biological fluids by chemiluminescence.
Methods in molecular biology (Clifton, N.J.).
2011; 704(?):27-37. doi:
10.1007/978-1-61737-964-2_3. [PMID: 21161627] - Denny Z Levett, Bernadette O Fernandez, Heather L Riley, Daniel S Martin, Kay Mitchell, Carl A Leckstrom, Can Ince, Brian J Whipp, Monty G Mythen, Hugh E Montgomery, Mike P Grocott, Martin Feelisch. The role of nitrogen oxides in human adaptation to hypoxia.
Scientific reports.
2011; 1(?):109. doi:
10.1038/srep00109. [PMID: 22355626]
