N-ethylmaleimide (BioDeep_00000003450)

 

Secondary id: BioDeep_00001867788

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione

化学式: C6H7NO2 (125.0476762)
中文名称: N-乙基顺丁烯二酰亚胺, N-乙基马来酰亚胺
谱图信息: 最多检出来源 Homo sapiens(blood) 33.05%

分子结构信息

SMILES: CCn(c(=O)1)c(=O)cc1
InChI: InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D013439 - Sulfhydryl Reagents
D004791 - Enzyme Inhibitors
KEIO_ID E008

同义名列表

7 个代谢物同义名

1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione; N-ethylmaleimide; N Ethylmaleimide; Ethylmaleimide; NEM; N-Ethylmaleimide; N-ethylmaleimide



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(97)

PlantCyc(15)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Li Zhang, Quan Yuan, Chaoyang Hu, Xue Sun, Yifu Gong, Nianjun Xu. Characterization of monogalactosyldiacylglycerol synthases in Gracilariopsis lemaneiformis and their potential roles in the fading of the thallus. Journal of phycology. 2023 12; 59(6):1258-1271. doi: 10.1111/jpy.13384. [PMID: 37688517]
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  • Mitchell R Mcgill, Hartmut Jaeschke. A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimide. Toxicology mechanisms and methods. 2015; 25(8):589-95. doi: 10.3109/15376516.2015.1094844. [PMID: 26461121]
  • Carlos Areche, Beatriz Sepulveda, Aurelio San Martin, Olimpo Garcia-Beltrán, Mario Simirgiotis, Alvaro Cañete. An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers. Organic & biomolecular chemistry. 2014 Sep; 12(33):6406-13. doi: 10.1039/c4ob00966e. [PMID: 25008488]
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  • Daniela Giustarini, Isabella Dalle-Donne, Aldo Milzani, Paolo Fanti, Ranieri Rossi. Analysis of GSH and GSSG after derivatization with N-ethylmaleimide. Nature protocols. 2013 Sep; 8(9):1660-9. doi: 10.1038/nprot.2013.095. [PMID: 23928499]
  • Quansheng Zhu, Xuesi M Shao, Liyo Kao, Rustam Azimov, Alan M Weinstein, Debra Newman, Weixin Liu, Ira Kurtz. Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. American journal of physiology. Cell physiology. 2013 Aug; 305(4):C392-405. doi: 10.1152/ajpcell.00044.2013. [PMID: 23636456]
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