Glycyrrhizin (BioDeep_00000003388)

 

Secondary id: BioDeep_00000230658, BioDeep_00000328812, BioDeep_00001869608

natural product human metabolite PANOMIX_OTCML-2023 Endogenous Chemicals and Drugs


代谢物信息卡片


5-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]-6-[(11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy]-3,4-dihydroxyoxane-2-carboxylic acid

化学式: C42H62O16 (822.4037652)
中文名称: 甘草酸
谱图信息: 最多检出来源 Viridiplantae(plant) 1.98%

分子结构信息

SMILES: C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2(C(=CC1=O)[C@H]1[C@@](CC2)(CC[C@](C1)(C)C(=O)O)C)C)C)C)(C)C)O[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](O1)C(=O)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](O1)C(=O)O)O)O)O
InChI: InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)

描述信息

Licoricesaponin H2 is found in herbs and spices. Licoricesaponin H2 is a constituent of Glycyrrhiza uralensis (Chinese licorice).
A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05B - Liver therapy, lipotropics > A05BA - Liver therapy
C1907 - Drug, Natural Product > C28269 - Phytochemical > C1905 - Triterpenoid Compound
Acquisition and generation of the data is financially supported in part by CREST/JST.
Isolated from Glycyrrhiza glabra (liquorice). Nutriceutical with anticancer props.
C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product
D000893 - Anti-Inflammatory Agents
KEIO_ID G057
Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.

同义名列表

28 个代谢物同义名

5-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]-6-[(11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy]-3,4-dihydroxyoxane-2-carboxylic acid; 6-({6-carboxy-2-[(11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy]-4,5-dihydroxyoxan-3-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylate; (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid; 30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosiduronic acid; Glycyrrhetic acid 3-O-[b-D-glucuronopyranosyl-(1->2)-a-D-glucuronopyranoside]; Glycyrrhizic acid ammonium salt; Glycyrrhizinate, Dipotassium; Dipotassium Glycyrrhizinate; Glycyrrhizinate, Diammonium; Diammonium Glycyrrhizinate; Ammonium glycyrrhizate; Acid, Glycyrrhizinic; Glycyrrhizate, Zinc; Glycyrrhizinic acid; Acid, Glycyrrhizic; Zinc Glycyrrhizate; beta-Glycyrrhizin; Glycyrrhizin, jan; Glycyrrhizic acid; Glycyrrhizinate; glycyrrhizate; Uralsaponin A; Glycyrrhizin; Glycyrrhitin; Glycyrrizin; Dermacrin; Glycyron; Glycyram



数据库引用编号

64 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sijue Chen, Wei Cao, Xianjun Xiao, Lu Wang, Renhong Wan, Zihao Zou, Qian Yang, Ying Li. A systematic review and meta-analysis of efficacy and safety of compound glycyrrhizin combined with second-generation non-sedated antihistamine for the treatment of chronic urticaria. The Journal of dermatological treatment. 2024 Dec; 35(1):2299597. doi: 10.1080/09546634.2023.2299597. [PMID: 38166511]
  • Jialing Sun, Mengqing Ma, Xin Zhong, Jing Li, Jinyu Yi, Renjie Zhang, Xingning Liu, Lanfen Peng, Xinfeng Sun, Wenxing Feng, Rui Hu, Qi Huang, Minling Lv, Kongli Fan, Xiaozhou Zhou. Investigating the molecular mechanism of Qizhu anticancer prescription in inhibiting hepatocellular carcinoma based on high-resolution mass spectrometry and network pharmacology. Journal of ethnopharmacology. 2024 Jun; 328(?):117985. doi: 10.1016/j.jep.2024.117985. [PMID: 38417600]
  • Shanbo Ma, Ye Chong, Rui Zhang, Wei Quan, Jiayue Gui, Long Li, Jin Wang, Shan Miao, Xiaopeng Shi, Minggao Zhao, Kun Zhang. Glycyrrhizic acid treatment ameliorates anxiety-like behaviour via GLT1 and Per1/2-dependent pathways. Journal of ethnopharmacology. 2024 Jun; 328(?):118013. doi: 10.1016/j.jep.2024.118013. [PMID: 38453099]
  • Yiting Hu, Zhongfei Luo, Siyi Cai, Qinfen Xie, Shusen Zheng. Glycyrrhizic acid attenuates sorafenib resistance by inducing ferroptosis via targeting mTOR signaling in hepatocellular carcinoma. Scandinavian journal of gastroenterology. 2024 Jun; 59(6):730-736. doi: 10.1080/00365521.2024.2315317. [PMID: 38426342]
  • Kai Chen, Yan-Yan Hu, Shan-Shan Qian, Jin-Zhao Wu, Li-Juan Cao, Lin-Lin Wang, Meng Li, Yu-Xin Xia, Qian Jiang, Hong-Ying Chen, Liu-Qing Chen, Dong-Sheng Li. A novel glycyrrhizic acid-based dressing effectively improved photodynamic therapy-caused skin barrier damage in port-wine stains. Journal of cosmetic dermatology. 2024 Jun; 23(6):2301-2303. doi: 10.1111/jocd.16250. [PMID: 38410871]
  • Hassan Esmaeili, Mohammad Hossein Mirjalili, Akbar Karami, Samad Nejad Ebrahimi. Introducing the glycyrrhizic acid and glabridin rich genotypes from the cultivated Iranian licorice (Glycyrrhiza glabra L.) populations to exploit in production systems. Scientific reports. 2024 05; 14(1):11034. doi: 10.1038/s41598-024-61711-1. [PMID: 38744977]
  • Lingfeng Du, Chunfang Ma, Bingnan Liu, Wei Liu, Yue Zhu, Zuhua Wang, Teng Chen, Luqi Huang, Yuxin Pang. Green Synthesis of Blumea balsamifera Oil Nanoemulsions Stabilized by Natural Emulsifiers and Its Effect on Wound Healing. Molecules (Basel, Switzerland). 2024 Apr; 29(9):. doi: 10.3390/molecules29091994. [PMID: 38731484]
  • Wenjing Su, Anna V Mastova, Maya A Ul'yanova, Polina A Kononova, Olga Yu Selyutina, Veronika I Evseenko, Elizaveta S Meteleva, Alexander V Dushkin, Weike Su, Nikolay E Polyakov. NMR Study of Water-Soluble Carotenoid Crocin: Formation of Mixed Micelles, Interaction with Lipid Membrane and Antioxidant Activity. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063194. [PMID: 38542168]
  • José Bryan García-Cambrón, José Luis Cerriteño-Sánchez, Rocío Lara-Romero, David Quintanar-Guerrero, Gerardo Blancas-Flores, Brenda L Sánchez-Gaytán, Irma Herrera-Camacho, Julieta Sandra Cuevas-Romero. Development of Glycyrrhizinic Acid-Based Lipid Nanoparticle (LNP-GA) as An Adjuvant That Improves the Immune Response to Porcine Epidemic Diarrhea Virus Spike Recombinant Protein. Viruses. 2024 03; 16(3):. doi: 10.3390/v16030431. [PMID: 38543796]
  • Longyue Zhou, Shankang Chen, Yuanyi Wei, Yihui Sun, Yifan Yang, Bingqi Lin, Yuhao Li, Chunxia Wang. Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitis. European journal of pharmacology. 2024 Feb; ?(?):176365. doi: 10.1016/j.ejphar.2024.176365. [PMID: 38316247]
  • Liangliang Chen, Lin Zhao, Ju Han, Ping Xiao, Mingzhe Zhao, Sen Zhang, Jinao Duan. Biosynthesis of Chryseno[2,1,c]oxepin-12-Carboxylic Acid from Glycyrrhizic Acid in Aspergillus terreus TMZ05-2, and Analysis of Its Anti-inflammatory Activity. Journal of microbiology (Seoul, Korea). 2024 Feb; 62(2):113-124. doi: 10.1007/s12275-024-00105-4. [PMID: 38411880]
  • Liu Zhou, Yifei Yang, Xiaotong Fu, Bing Xia, Chun Li, Chenna Lu, Ying Qi, Haijing Zhang, Ting Liu. The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway. Journal of ethnopharmacology. 2024 Jan; 319(Pt 1):117100. doi: 10.1016/j.jep.2023.117100. [PMID: 37648177]
  • Rui Zhang, Aiminuer Asikaer, Qi Chen, Fang Wang, Junjie Lan, Yang Liu, Linfang Hu, Huaye Zhao, Hongtao Duan. Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and STAT3 signaling pathways. BMC complementary medicine and therapies. 2024 Jan; 24(1):58. doi: 10.1186/s12906-024-04372-x. [PMID: 38280993]
  • Peter Fischer, Viviane Lutz-Bueno. Glycyrrhizic acid aggregates seen from a synthetic surfactant perspective. Physical chemistry chemical physics : PCCP. 2024 Jan; 26(4):2806-2814. doi: 10.1039/d3cp04835g. [PMID: 38196347]
  • Xuecheng Wang, Xiaohui Wang, Yutian Zhang, Yaqi Wang, Yuanhui Li, Yaokun Xiong, Ming Yang, Xiaorong Luo, Zhenfeng Wu. Effects of ultrasonic power on drying kinetics and product quality of licorice extract during ultrasound-assisted vacuum drying. Journal of the science of food and agriculture. 2024 Jan; ?(?):. doi: 10.1002/jsfa.13283. [PMID: 38252708]
  • Yaoyao Xiao, Lele Zhou, Wenkang Tao, Xuan Yang, Junying Li, Rulin Wang, Yanan Zhao, Can Peng, Caiyun Zhang. Preparation of paeoniflorin-glycyrrhizic acid complex transethosome gel and its preventive and therapeutic effects on melasma. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2024 Jan; 192(?):106664. doi: 10.1016/j.ejps.2023.106664. [PMID: 38061662]
  • Yu Mou, Wenhao Liao, Yuchen Li, Lina Wan, Jingwen Liu, Xialing Luo, Hongping Shen, Qin Sun, Jing Wang, Jianyuan Tang, Zhilei Wang. Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases. The American journal of Chinese medicine. 2024; 52(2):315-354. doi: 10.1142/s0192415x24500149. [PMID: 38553799]
  • Kavita J Lanjekar, Virendra K Rathod. Recovery and separation of glycyrrhizic acid from Natural Deep Eutectic Solvent (NADES) extract by macroporous resin: adsorption kinetics and isotherm studies. Preparative biochemistry & biotechnology. 2024 Jan; 54(1):39-48. doi: 10.1080/10826068.2023.2204485. [PMID: 37204086]
  • Naoki Chiyo, Hikaru Seki, Takuya Kanamoto, Hiroshi Ueda, Mareshige Kojoma, Toshiya Muranaka. Glycyrrhizin Production in Licorice Hairy Roots Based on Metabolic Redirection of Triterpenoid Biosynthetic Pathway by Genome Editing. Plant & cell physiology. 2023 Dec; ?(?):. doi: 10.1093/pcp/pcad161. [PMID: 38153756]
  • Manami Sakanishi, Soo Yeon Chung, Kentaro Fujiwara, Mareshige Kojoma, Toshiya Muranaka, Hikaru Seki. Disruption of a licorice cellulose synthase-derived glycosyltransferase gene demonstrates its in planta role in soyasaponin biosynthesis. Plant cell reports. 2023 Dec; 43(1):15. doi: 10.1007/s00299-023-03095-6. [PMID: 38135741]
  • Ruchi Sharma, Rajeev K Singla, Subhadip Banerjee, Rohit Sharma. Revisiting Licorice as a functional food in the management of neurological disorders: bench to trend. Neuroscience and biobehavioral reviews. 2023 Nov; ?(?):105452. doi: 10.1016/j.neubiorev.2023.105452. [PMID: 37925093]
  • Yang Jian, Xiaoyu Wang, Yunming Li, Dali Fu, Yalin Gong, Huiqing Shi. Efficacy and safety of compound glycyrrhizin in combination with conventional therapy in treatment of vitiligo: A systematic review and meta-analysis of randomized controlled trials. Medicine. 2023 Oct; 102(43):e35533. doi: 10.1097/md.0000000000035533. [PMID: 37904437]
  • Chengcheng Wang, Dawei Wu, Liying Jiang, Xunhong Liu, Tiantian Xie. Multi-Omics Elucidates Difference in Accumulation of Bioactive Constituents in Licorice (Glycyrrhiza uralensis) under Drought Stress. Molecules (Basel, Switzerland). 2023 Oct; 28(20):. doi: 10.3390/molecules28207042. [PMID: 37894521]
  • Kun Ren, Xuanmeng Zhang, Ruijie Wang, Shumeng Ren, Huiming Hua, Dongmei Wang, Yingni Pan, Xiaoqiu Liu. The inhibitory effect of licorice on the hepatotoxicity induced by the metabolic activation of Euodiae Fructus. Journal of ethnopharmacology. 2023 Oct; 319(Pt 2):117233. doi: 10.1016/j.jep.2023.117233. [PMID: 37793580]
  • Fengyu Dong, Mengdi Xie, Manwen Xu, Lu Lu, Yan Miao, Panpan Zhang, Xiaopeng Li, Xinjing Gui, Ruixin Liu. Quality consistency evaluation of chemical composition and pharmacology of Shaoyao-Gancao decoction dispensing granules and traditional decoction. Biomedical chromatography : BMC. 2023 Sep; ?(?):e5745. doi: 10.1002/bmc.5745. [PMID: 37736670]
  • Jingyuan Zeng, Xican Li, Rongxin Cai, Ban Chen, Chunhou Li, Qingzhong Hu, Yue Sun. Proposing anti-counterfeiting pharmacopoeia quality markers for Shenlingbaizhu granule based on UHPLC-Q-orbitrap-MS identification. Phytochemical analysis : PCA. 2023 Sep; ?(?):. doi: 10.1002/pca.3284. [PMID: 37735858]
  • Jishuai Sun, Mingyang Sun, Jiachen Zang, Tuo Zhang, Chenyan Lv, Guanghua Zhao. Highly Stretchable, Transparent, and Adhesive Double-Network Hydrogel Dressings Tailored with Fish Gelatin and Glycyrrhizic Acid for Wound Healing. ACS applied materials & interfaces. 2023 Sep; 15(36):42304-42316. doi: 10.1021/acsami.3c09615. [PMID: 37647580]
  • Ziyi Xu, Yu Huang, Yihan Wu, Jiamei Chen, Sai-Wang Seto, George Pak-Heng Leung, Yin Cai, Jingjing Li, Jinming Zhang. Glycyrrhizic Acid-Lipid Framework Nanovehicle Loading Triptolide for Combined Immunochemotherapy. ACS applied materials & interfaces. 2023 Aug; ?(?):. doi: 10.1021/acsami.3c08003. [PMID: 37615350]
  • Yue Zhu, Teng Chen, Tingting Feng, Jiaojiao Zhang, Zejing Meng, Ning Zhang, Gang Luo, Zuhua Wang, Yuxin Pang, Ying Zhou. Fabrication and Biological Activities of All-in-One Composite Nanoemulsion Based on Blumea balsamifera Oil-Tea Tree Oil. Molecules (Basel, Switzerland). 2023 Aug; 28(15):. doi: 10.3390/molecules28155889. [PMID: 37570859]
  • Zhuobin Xu, Ze Xu, Jiake Gu, Juan Zhou, Gengyu Sha, Ying Huang, Tong Wang, Lei Fan, Yanfeng Zhang, Juqun Xi. In situ formation of ferrous sulfide in glycyrrhizic acid hydrogels to promote healing of multi-drug resistant Staphylococcus aureus-infected diabetic wounds. Journal of colloid and interface science. 2023 Jul; 650(Pt B):1918-1929. doi: 10.1016/j.jcis.2023.07.141. [PMID: 37517191]
  • Dalia Elebeedy, Aml Ghanem, Shaza H Aly, Mohamed A Ali, Ahmed H I Faraag, Mohamed K El-Ashrey, Aya M Salem, Mahmoud A El Hassab, Ahmed I Abd El Maksoud. Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and In Silico insights. BMC microbiology. 2023 06; 23(1):173. doi: 10.1186/s12866-023-02911-z. [PMID: 37391715]
  • Xia Cao, Tianwen Deng, Qin Zhu, Jianping Wang, Wenwan Shi, Qi Liu, Qintong Yu, Wenwen Deng, Jiangnan Yu, Qilong Wang, Gao Xiao, Ximing Xu. Photothermal Therapy Mediated Hybrid Membrane Derived Nano-formulation for Enhanced Cancer Therapy. AAPS PharmSciTech. 2023 Jun; 24(6):146. doi: 10.1208/s12249-023-02594-9. [PMID: 37380936]
  • Monojit Bhattacharjee, Suryaa Manoharan, Umamaheswari Sathisaran, Anand Tamatam, Ekambaram Perumal. MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L. Journal of biomolecular structure & dynamics. 2023 May; ?(?):1-19. doi: 10.1080/07391102.2023.2216298. [PMID: 37243713]
  • Yang Liu, Hao Wang, Xun Qian, Jie Gu, Weimin Chen, Xihui Shen, Shiheng Tao, Shuo Jiao, Gehong Wei. Metagenomics insights into responses of rhizobacteria and their alleviation role in licorice allelopathy. Microbiome. 2023 05; 11(1):109. doi: 10.1186/s40168-023-01511-3. [PMID: 37211607]
  • Tahereh Naseriyeh, Danial Kahrizi, Hosna Alvandi, Faranak Aghaz, Ghazal Nowroozi, Alireza Shamsi, Omid Hosseini, Elham Arkan. Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Apr; 69(4):1-6. doi: 10.14715/cmb/2023.69.4.1. [PMID: 37329555]
  • Jun-Pu Yang, Amin Ullah, Ya-Nan Su, Antonia Otoo, Enoch Appiah Adu-Gyamfi, Qian Feng, Ying-Xiong Wang, Mei-Jiao Wang, Yu-Bin Ding. Glycyrrhizin ameliorates impaired glucose metabolism and ovarian dysfunction in a polycystic ovary syndrome mouse model. Biology of reproduction. 2023 Apr; ?(?):. doi: 10.1093/biolre/ioad048. [PMID: 37115805]
  • Kei Kawada, Tomoaki Ishida, Kohei Jobu, Shumpei Morisawa, Motoki Nishida, Naohisa Tamura, Saburo Yoshioka, Mitsuhiko Miyamura. Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model. Journal of natural medicines. 2023 Apr; ?(?):. doi: 10.1007/s11418-023-01700-2. [PMID: 37115471]
  • Alireza Poustforoosh, Sanaz Faramarz, Manica Negahdaripour, Burak Tüzün, Hassan Hashemipour. Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods. Journal of biomolecular structure & dynamics. 2023 Apr; ?(?):1-15. doi: 10.1080/07391102.2023.2196347. [PMID: 37042955]
  • Yun Chen, Weiqiang Han, Shanshan Li, Yuntao Nie, Peng Chen, Juan Sun, Yuhua Chen, Lisha Li. Effects of mesotherapy introduction of compound glycyrrhizin injection on the treatment of moderate to severe acne. Journal of cosmetic dermatology. 2023 Apr; ?(?):. doi: 10.1111/jocd.15681. [PMID: 37036158]
  • W Caré, G Grenet, C Schmitt, S Michel, J Langrand, G Le Roux, D Vodovar. [Adverse effects of licorice consumed as food: An update]. La Revue de medecine interne. 2023 Mar; ?(?):. doi: 10.1016/j.revmed.2023.03.004. [PMID: 37005098]
  • Yanyan Wang, Shuhua An. A rare pathogen causing pulmonary infection and liver dysfunction in a 46-day-old infant: Rhizobium radiobacter. Paediatrics and international child health. 2023 Mar; ?(?):1-4. doi: 10.1080/20469047.2023.2188383. [PMID: 36914262]
  • JunMei Wang, Chunxiu Ren, WenHui Bi, Wuliji Batu. Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo. Journal of ethnopharmacology. 2023 Mar; 303(?):115948. doi: 10.1016/j.jep.2022.115948. [PMID: 36423713]
  • Shasha Kong, Pengyue Li, Robert Verpoorte, Mingqian Li, Yuntao Dai. Chemical and pharmacological difference between honey-fried licorice and fried licorice. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115841. doi: 10.1016/j.jep.2022.115841. [PMID: 36270557]
  • Xin Xu, Tong Wei, Qianqian Xue, Jiahao Ai, Guixin Li, Zhongguo Liu, Dan Li, Jincai Hou, Hongli Jin, Yanfang Liu, Xinmiao Liang. [Analysis on quality value transmitting of Qinggusan reference sample of classical prescription based on quantitative fingerprint technology]. Se pu = Chinese journal of chromatography. 2023 Feb; 41(2):142-151. doi: 10.3724/sp.j.1123.2022.09024. [PMID: 36725710]
  • Qiming Yin, Xiang Song, Peng Yang, Wen Yang, Xinyu Li, Xuejun Wang, Shengqi Wang. Incorporation of glycyrrhizic acid and polyene phosphatidylcholine in lipid nanoparticles ameliorates acute liver injury via delivering p65 siRNA. Nanomedicine : nanotechnology, biology, and medicine. 2023 02; 48(?):102649. doi: 10.1016/j.nano.2022.102649. [PMID: 36584740]
  • Ting-Ting Yi, Li-Mei Zhang, Xiang-Nan Huang. Glycyrrhizic acid protects against temporal lobe epilepsy in young rats by regulating neuronal ferroptosis through the miR-194-5p/PTGS2 axis. The Kaohsiung journal of medical sciences. 2023 Feb; 39(2):154-165. doi: 10.1002/kjm2.12642. [PMID: 36647717]
  • Youngseok Ham, Tae-Jong Kim. Synergistic inhibitory activity of Glycyrrhizae Radix and Rubi Fructus extracts on biofilm formation of Streptococcus mutans. BMC complementary medicine and therapies. 2023 Jan; 23(1):22. doi: 10.1186/s12906-023-03861-9. [PMID: 36709283]
  • Huihui Xu, Liang Fang, Qinghe Zeng, Jiali Chen, Houfu Ling, Hanting Xia, Qinwen Ge, Congzi Wu, Kaiao Zou, Xu Wang, Pinger Wang, Wenhua Yuan, Rui Dong, Songfeng Hu, Luwei Xiao, Bangjian He, Peijian Tong, Hongting Jin. Glycyrrhizic acid alters the hyperoxidative stress-induced differentiation commitment of MSCs by activating the Wnt/β-catenin pathway to prevent SONFH. Food & function. 2023 Jan; 14(2):946-960. doi: 10.1039/d2fo02337g. [PMID: 36541285]
  • Ulises Zendejas-Hernandez, Nemi Alcántara-Martínez, Diana Tovar Vivar, Fermín Valenzuela, Alejandro Sosa Espinoza, Eduardo Emir Cervera Ceballos. Nebulized glycyrrhizin/enoxolone drug modulates IL-17A in COVID-19 patients: a randomized clinical trial. Frontiers in immunology. 2023; 14(?):1282280. doi: 10.3389/fimmu.2023.1282280. [PMID: 38283346]
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