(S)-2-Azetidinecarboxylic acid (BioDeep_00000003359)
Secondary id: BioDeep_00001868719
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
1-Azetidinecarboxylicacid, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2S)-
化学式: C4H7NO2 (101.0477)
中文名称: 氮杂环丁烷-2-羧酸, L-铃兰氨酸, L-氮杂环丁烷-2-羧酸, （S） -氮杂环丁烷-2-羧酸, DL-氮杂环丁烷-2-羧酸
谱图信息:
最多检出来源 Mus musculus(otcml) 2.97%
分子结构信息
SMILES: C1CNC1C(=O)O
InChI: InChI=1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)
描述信息
Azetidine-2-carboxylic acid is an azetidinecarboxylic acid that is azetidine substituted by a carboxy group at position 2. It is a plant non-protein amino acid. It has a role as a plant metabolite and a teratogenic agent. It is an azetidinecarboxylic acid and an amino acid.
A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activity.
(S)-2-Azetidinecarboxylic acid is found in common beet. (S)-2-Azetidinecarboxylic acid is present in roots and leaves of Convallaria majalis (lily-of-the-valley). Convallaria majalis is banned by the FDA from food use in the US
Present in roots and leaves of Convallaria majalis (lily-of-the-valley). Convallaria majalis is banned by the FDA from food use in the USA. (S)-2-Azetidinecarboxylic acid is found in red beetroot and common beet.
An azetidinecarboxylic acid that is azetidine substituted by a carboxy group at position 2. It is a plant non-protein amino acid.
KEIO_ID A219
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent[1][2].
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent[1][2].
L-Azetidine-2-carboxylic acid is an endogenous metabolite.
L-Azetidine-2-carboxylic acid is an endogenous metabolite.
同义名列表
46 个代谢物同义名
1-Azetidinecarboxylicacid, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2S)-; L-azetidine-2-carboxylic acid;(2S)-azetidine-2-carboxylic acid; azetidine-2-carboxylic acid, AldrichCPR; 2-Azetidinecarboxylic acid, (S)- (9CI); (2S)-(-)-Azetidine-2-carboxylic acid; (S)-(-)-Azetidine-2-carboxylic acid; 2-AZETIDINECARBOXYLIC ACID, (+/-)-; 2-AZETIDINECARBOXYLIC ACID, (RS)-; (2S)-Azetidine-2-carboxylic acid; (+/-)-2-AZETIDINECARBOXYLIC ACID; Boc-L-azetidine-2carboxylic acid; AZETIDINE-2-CARBOXYLICACID (L-); (2S)-2-Azetidinecarboxylic acid; 2-AZETIDINECARBOXYLIC ACID [MI]; (L)-Azetidine-2-carboxylic acid; D,L-Azetidine-2-carboxylic Acid; (+-)-2-Azetidinecarboxylic acid; (S)-Azetidine-2-carboxylic acid; DL-Azetidine-2-carboxylic acid; (S)-2-Azetidinecarboxylic acid; L-Azetidine 2-carboxylic acid; L-Azetidine-2-carboxylic acid; DL-2-Azetidinecarboxylic acid; L-2-Azetidinecarboxylic acid; Acid, azetidine-2-carboxylic; Azetidine-2-carboxylic acid; Azetidine 2 carboxylic Acid; Azetidine 3 carboxylic Acid; Azetidine-3-carboxylic Acid; acetidine 2-carboxylic acid; 2-AZETIDINECARBOXYLIC ACID; 3-azetidinecarboxylic Acid; Azetidyl-2-carboxylic acid; (S)-2-Azetidinecarboxylate; 3 azetidinecarboxylic Acid; azetidine-2-carboxylicacid; Acid, azetidinecarboxylic; Azetidinecarboxylic acid; Azetidine-2-carboxylate; D,L-AzeOH; DL-AzeOH; H-Aze-OH; AZC; 2-Azetidinecarboxylic acid, (S)-; (S)-Azetidine-2-carboxylic acid; L-Azetidine 2-carboxylic acid
数据库引用编号
32 个数据库交叉引用编号
- ChEBI: CHEBI:38108
- ChEBI: CHEBI:6198
- KEGG: C08267
- PubChem: 17288
- PubChem: 16486
- HMDB: HMDB0029615
- Metlin: METLIN66875
- ChEMBL: CHEMBL33592
- ChEMBL: CHEMBL1165239
- Wikipedia: Azetidine-2-carboxylic_acid
- MeSH: Azetidinecarboxylic Acid
- ChemIDplus: 0002517046
- KNApSAcK: C00001343
- foodb: FDB000783
- chemspider: 16360
- CAS: 20063-89-2
- CAS: 2517-04-6
- CAS: 2133-34-8
- CAS: 4/6/2517
- MoNA: KO000298
- MoNA: KO000299
- MoNA: KO000297
- medchemexpress: HY-75308
- PMhub: MS000009540
- MetaboLights: MTBLC38108
- PubChem: 10466
- PDB-CCD: 02A
- NIKKAJI: J35.234I
- medchemexpress: HY-W050044
- KNApSAcK: 6198
- LOTUS: LTS0201230
- wikidata: Q793715
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xi Wu, Yafeng Jia, Qian Ma, Tingting Wang, Jiena Xu, Hongli Chen, Mingxia Wang, Hui Song, Shuqing Cao. The transcription factor bZIP44 cooperates with MYB10 and MYB72 to regulate the response of Arabidopsis thaliana to iron deficiency stress.
The New phytologist.
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Journal of labelled compounds & radiopharmaceuticals.
2023 11; 66(13):428-434. doi:
10.1002/jlcr.4064. [PMID: 37755147] - Lijuan Han, Wangyu Zhao, Aijuan Li, Bo Zhou, Jiwen Zhang, Wenjun Wu. Antifungal activity of l-azetidine-2-carboxylic acid isolated from Disporopsis aspera rhizomes against Podosphaera xanthii.
Pest management science.
2022 May; 78(5):1946-1952. doi:
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Plant physiology.
2022 03; 188(4):2131-2145. doi:
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International journal of molecular sciences.
2015 Aug; 16(8):19111-29. doi:
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Biomedical chromatography : BMC.
2015 Jul; 29(7):970-4. doi:
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Clinical and experimental nephrology.
2015 Jun; 19(3):465-73. doi:
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Physiologia plantarum.
2015 Jun; 154(2):243-55. doi:
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The New phytologist.
2015 Apr; 206(2):738-50. doi:
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Biomedical research (Tokyo, Japan).
2015; 36(3):219-24. doi:
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Plant signaling & behavior.
2015; 10(6):e1031940. doi:
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The Plant journal : for cell and molecular biology.
2015 Jan; 81(2):233-46. doi:
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PloS one.
2015; 10(7):e0132500. doi:
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Journal of labelled compounds & radiopharmaceuticals.
2014 Nov; 57(13):710-4. doi:
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Plant physiology.
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Plant physiology.
2014 Oct; 166(2):839-52. doi:
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The New phytologist.
2014 Sep; 203(4):1161-1174. doi:
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Plant science : an international journal of experimental plant biology.
2014 Aug; 225(?):52-7. doi:
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Electrophoresis.
2014 May; 35(9):1375-85. doi:
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Journal of cardiovascular pharmacology and therapeutics.
2014 May; 19(3):304-9. doi:
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PloS one.
2014; 9(9):e107853. doi:
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Plant, cell & environment.
2013 Oct; 36(10):1888-902. doi:
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The Annals of thoracic surgery.
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Plant science : an international journal of experimental plant biology.
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Analytical and bioanalytical chemistry.
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Biological & pharmaceutical bulletin.
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The Tohoku journal of experimental medicine.
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British journal of pharmacology.
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