Pyrrole 2-carboxylate (BioDeep_00000334833)

Main id: BioDeep_00000001421

Secondary id: BioDeep_00000869344

PANOMIX_OTCML-2023

代谢物信息卡片

Pyrrole-3-carboxylic acid

化学式: C5H5NO2 (111.032027)
中文名称: 3-吡咯羧酸, 吡咯-2-甲酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CNC(=C1)C(=O)O
InChI: InChI=1S/C5H5NO2/c7-5(8)4-1-2-6-3-4/h1-3,6H,(H,7,8)

描述信息

A pyrrolecarboxylic acid that is 1H-pyrrole substituted by a carboxy group at position 3. It has been isolated from Penicillium chrysogenum.
A pyrrolecarboxylic acid that is 1H-pyrrole carrying a carboxy substituent at position 2.
Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov.
Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov.

同义名列表

3 个代谢物同义名

Pyrrole-3-carboxylic acid; Pyrrole 2-carboxylate; PYRROLE-2-CARBOXYLIC ACID

数据库引用编号

22 个数据库交叉引用编号

ChEBI: CHEBI:68076
ChEBI: CHEBI:36751
KEGG: C05942
PubChem: 101030
PubChem: 12473
DrugBank: DB02543
ChEMBL: CHEMBL79155
ChEMBL: CHEMBL509027
CAS: 931-03-3
CAS: 634-97-9
MoNA: HMDB0004230_ms_ms_2378
MoNA: HMDB0004230_ms_ms_2377
MoNA: HMDB0004230_ms_ms_2376
PMhub: MS000128824
MetaboLights: MTBLC68076
MetaboLights: MTBLC36751
PubChem: 8227
KNApSAcK: C00043859
PDB-CCD: PYC
3DMET: B00881
NIKKAJI: J1.713B
medchemexpress: HY-W001963

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

67385 Streptomyces xanthophaeus: 10.1080/14786419.2016.1269100
3055 Chlamydomonas reinhardtii: 10.1074/JBC.M110.122812
65558 Capparis spinosa: 10.1021/JF302075W
1883 Streptomyces:
1205701 Brachystemma calycinum:
35619 Streptomyces griseoflavus: 10.1002/JLAC.198319830509
1911 Streptomyces griseus: 10.1002/JOBM.201300820
5076 Penicillium chrysogenum: 10.1021/NP1008976
67385 Streptomyces xanthophaeus: 10.1080/14786419.2016.1269100
3055 Chlamydomonas reinhardtii: 10.1074/JBC.M110.122812
65558 Capparis spinosa: 10.1021/JF302075W
1883 Streptomyces:
1205701 Brachystemma calycinum:
35619 Streptomyces griseoflavus: 10.1002/JLAC.198319830509
1911 Streptomyces griseus: 10.1002/JOBM.201300820
569774 金线莲: -
418402 Pseudostellaria heterophylla (Miq.) Pax ex Pax et Hoffm: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Nishant K Rasal, Rahul B Sonawane, Sangeeta V Jagtap. Synthesis, biological evaluation, and in silico study of pyrazoline-conjugated 2,4-dimethyl-1H-pyrrole-3-carboxylic acid derivatives. Archiv der Pharmazie. 2021 Feb; 354(2):e2000267. doi: 10.1002/ardp.202000267. [PMID: 33078449]
Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
Yeo Ul Cho, Deokjong Lee, Jung-Eun Lee, Kyoung Heon Kim, Do Yup Lee, Young-Chul Jung. Exploratory metabolomics of biomarker identification for the internet gaming disorder in young Korean males. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Jul; 1057(?):24-31. doi: 10.1016/j.jchromb.2017.04.046. [PMID: 28482325]
Seyda Korkut, Muhammet Samet Kilic. Design of a mediated enzymatic fuel cell to generate power from renewable fuel sources. Environmental technology. 2016; 37(2):163-71. doi: 10.1080/09593330.2015.1065007. [PMID: 26102352]
Guidong Liu, Xiaochang Dong, Leichao Liu, Lishu Wu, Shu'ang Peng, Cuncang Jiang. Metabolic profiling reveals altered pattern of central metabolism in navel orange plants as a result of boron deficiency. Physiologia plantarum. 2015 Apr; 153(4):513-24. doi: 10.1111/ppl.12279. [PMID: 25212059]
Evagelia C Laiakis, Gerard A J Morris, Albert J Fornace, Stephen R C Howie. Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study. PloS one. 2010 Sep; 5(9):. doi: 10.1371/journal.pone.0012655. [PMID: 20844590]
Atanu Biswas, Brajendra K Sharma, Kenneth M Doll, Sevim Z Erhan, Julious L Willett, H N Cheng. Synthesis of an amine-oleate derivative using an ionic liquid catalyst. Journal of agricultural and food chemistry. 2009 Sep; 57(18):8136-41. doi: 10.1021/jf901401s. [PMID: 19719124]
Keisuke Kagami, Kenji Onda, Kitaro Oka, Toshihiko Hirano. Suppression of blood lipid concentrations by volatile Maillard reaction products. Nutrition (Burbank, Los Angeles County, Calif.). 2008 Nov; 24(11-12):1159-66. doi: 10.1016/j.nut.2008.05.010. [PMID: 18586457]
Zhen-Jian Lin, Xiao-Ming Lu, Tian-Jiao Zhu, Yu-Chun Fang, Qian-Qun Gu, Weiming Zhu. GPR12 selections of the metabolites from an endophytic Streptomyces sp. associated with Cistanches deserticola. Archives of pharmacal research. 2008 Sep; 31(9):1108-14. doi: 10.1007/s12272-001-1276-4. [PMID: 18806952]
Tim Sparey, Pravien Abeywickrema, Sarah Almond, Nick Brandon, Noel Byrne, Alister Campbell, Pete H Hutson, Marlene Jacobson, Brian Jones, Sanjeev Munshi, Danette Pascarella, Andrew Pike, G Sridhar Prasad, Nancy Sachs, Melanie Sakatis, Vinod Sardana, Shankar Venkatraman, Mary Beth Young. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorganic & medicinal chemistry letters. 2008 Jun; 18(11):3386-91. doi: 10.1016/j.bmcl.2008.04.020. [PMID: 18455394]
M O Lederer, M Baumann. Formation of a phospholipid-linked pyrrolecarbaldehyde from model reactions of D-glucose and 3-deoxyglucosone with phosphatidyl ethanolamine. Bioorganic & medicinal chemistry. 2000 Jan; 8(1):115-21. doi: 10.1016/s0968-0896(99)00264-3. [PMID: 10968270]
M Wajner, C M Wannmacher, P Purkiss. High urinary excretion of N-(pyrrole-2-carboxyl) glycine in type II hyperprolinemia. Clinical genetics. 1990 Jun; 37(6):485-9. doi: 10.1111/j.1399-0004.1990.tb03535.x. [PMID: 2383933]
J H Dreisbach, A Veca. Rapid method for the analysis of urinary pyrrole-2-carboxylic acid using reversed-phase high-performance liquid chromatography. Journal of chromatography. 1986 Oct; 382(?):280-3. doi: 10.1016/s0378-4347(00)83530-6. [PMID: 3782395]
E Svojtková, Z Deyl, J Andrlíková. Decrease in pyrrole-2-carboxylic acid excretion during lung cancer disease. Neoplasma. 1982; 29(5):625-9. doi: . [PMID: 7177252]
G B GERBER, K R TRAELNES, D WOOD, K I ALTMAN. THE QUANTITATIVE DETERMINATION OF PYRROLE-2-CARBOXYLIC ACID IN URINE. Clinica chimica acta; international journal of clinical chemistry. 1964 Feb; 9(?):185-7. doi: 10.1016/0009-8981(64)90015-4. [PMID: 14122509]
K KONNO, K R TRAELNES, K I ALTMAN. THE EFFECT OF WHOLE- AND PARTIAL-BODY X-IRRADIATION ON THE METABOLISM OF COLLAGEN IN POLYETHYLENE SPONGES AND THE URINARY EXCRETION OF PYRROLE-2-CARBOXYLIC ACID. International journal of radiation biology and related studies in physics, chemistry, and medicine. 1964; 8(?):367-72. doi: 10.1080/09553006414550431. [PMID: 14274308]