Chlorpropham (BioDeep_00000003052)

 

Secondary id: BioDeep_00000858447

human metabolite blood metabolite


代谢物信息卡片


(3-Chlorophenyl)carbamic acid, 1-methylethyl ester

化学式: C10H12ClNO2 (213.0556522)
中文名称: 乙腈中氯苯胺灵溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 0.25%

分子结构信息

SMILES: CC(C)OC(=O)NC1=CC(=CC=C1)Cl
InChI: InChI=1S/C10H12ClNO2/c1-7(2)14-10(13)12-9-5-3-4-8(11)6-9/h3-7H,1-2H3,(H,12,13)

描述信息

D006133 - Growth Substances > D010937 - Plant Growth Regulators
CONFIDENCE standard compound; INTERNAL_ID 2623
CONFIDENCE standard compound; INTERNAL_ID 8450
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

47 个代谢物同义名

(3-Chlorophenyl)carbamic acid, 1-methylethyl ester; N-(3-Chlorophenyl)carbamic acid, isopropyl ester; (3-Chlorophenyl)carbamate, 1-methylethyl ester; N-(3-Chlorophenyl)carbamate, isopropyl ester; 1-Methylethyl (3-chlorophenyl)carbamic acid; O-Isopropyl N-(3-chlorophenyl)carbamic acid; Isopropyl-N-(3-chlorophenyl)carbamic acid; N-(3-Chlorophenyl)isopropyl carbamic acid; Isopropyl N-(m-chlorophenyl)carbamic acid; Isopropyl N-(3-chlorophenyl)carbamic acid; Isopropyl-N-3-chlorophenyl carbamic acid; 3-Chlorocarbanilic acid, isopropyl ester; m-Chlorocarbanilic acid, isopropyl ester; Isopropyl-N-m-chlorophenyl-carbamic acid; propan-2-yl N-(3-chlorophenyl)carbamate; O-Isopropyl N-(3-chlorophenyl)carbamate; 1-Methylethyl (3-chlorophenyl)carbamate; Isopropyl (3-chlorophenyl)carbamic acid; m-Chlorocarbanilic acid isopropyl ester; N-3-Chlorophenylisopropylcarbamic acid; Isopropyl N-(3-chlorophenol)carbamate; Isopropyl 3-chlorophenylcarbamic acid; N-(3-Chlorophenyl)isopropyl carbamate; Isopropyl N-(3-chlorophenyl)carbamate; Isopropyl N-(m-chlorophenyl)carbamate; Isopropyl-N-(3-chlorophenyl)carbamate; Isopropyl-N-m-chlorophenyl-carbamate; 3-Chlorocarbanilate, isopropyl ester; Isopropyl meta-chlorocarbanilic acid; m-Chlorocarbanilate, isopropyl ester; Isopropyl-N-(3-chlorphenyl)-carbamat; Isopropyl-N-3-chlorophenyl carbamate; m-Chlorocarbanilate isopropyl ester; Isopropyl (3-chlorophenyl)carbamate; N-3-Chlorophenylisopropylcarbamate; Isopropyl 3-chlorophenylcarbamate; Isopropyl m-chlorocarbanilic acid; Isopropyl 3-chlorocarbanilic acid; Isopropyl-m-chlorocarbanilic acid; Isopropyl meta-chlorocarbanilate; Isopropyl m-chlorocarbanilate; Isopropyl-m-chlorocarbanilate; Isopropyl 3-chlorocarbanilate; Chloropropham; Chlorprophame; chlorpropham; CIPC



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Marcelo Rodrigo Krause, Fernanda Ferreira de Araujo, Karoliny Ferreira Moreira, Nícolas Oliveira de Araújo, Jean Paulo de Jesus Tello, Mirelle Nayana de Sousa Santos, Fernando Luiz Finger. Carbohydrate metabolism dynamic in chlorpropham- and 1,4-dimethylnaphthalene-treated potatoes and its effect on the browning of French fries. Food chemistry. 2023 Jul; 429(?):136718. doi: 10.1016/j.foodchem.2023.136718. [PMID: 37487392]
  • Lixia Yang, Xiaobei Huang, Xike Zeng, Zi Yi. [Determination of chlorpropham residues in animal-derived foods by solid phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2022 Jan; 40(1):41-47. doi: 10.3724/sp.j.1123.2021.02009. [PMID: 34985214]
  • Bernd Göckener, Matthias Kotthoff, Hans-Willi Kling, Mark Bücking. Fate of Chlorpropham during High-Temperature Processing of Potatoes. Journal of agricultural and food chemistry. 2020 Feb; 68(8):2578-2587. doi: 10.1021/acs.jafc.9b06386. [PMID: 31961151]
  • Namadev K Pujar, H G Premakshi, Shruti Laad, Shridhar V Pattar, Manisha Mirjankar, Chandrappa M Kamanavalli. Biodegradation of chlorpropham and its major products by Bacillus licheniformis NKC-1. World journal of microbiology & biotechnology. 2018 Jul; 34(8):112. doi: 10.1007/s11274-018-2494-8. [PMID: 29980862]
  • Christian Berchtold, Vivian Müller, Lukas Meier, Stefan Schmid, Renato Zenobi. Direct detection of chlorpropham on potato skin using desorption electrospray ionization. Journal of mass spectrometry : JMS. 2013 May; 48(5):587-93. doi: 10.1002/jms.3197. [PMID: 23674283]
  • Dinar S C Wahyuni, Frank van der Kooy, Peter G L Klinkhamer, Rob Verpoorte, Kirsten Leiss. The use of bio-guided fractionation to explore the use of leftover biomass in Dutch flower bulb production as allelochemicals against weeds. Molecules (Basel, Switzerland). 2013 Apr; 18(4):4510-25. doi: 10.3390/molecules18044510. [PMID: 23595089]
  • P S Lakshmanan, T Eeckhaut, J Van Huylenbroeck, E Van Bockstaele. Micronucleation by mitosis inhibitors in developing microspores of Spathiphyllum wallisii Regel. Plant cell reports. 2013 Mar; 32(3):369-77. doi: 10.1007/s00299-012-1370-5. [PMID: 23179462]
  • Margaret J Smith, Sandra Müller, Wolfram Sander, Götz Bucher. Mechanisms of the thermal decay of chlorpropham. Journal of hazardous materials. 2013 Feb; 246-247(?):154-62. doi: 10.1016/j.jhazmat.2012.12.003. [PMID: 23295769]
  • Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology. 2011 Feb; 280(3):77-87. doi: 10.1016/j.tox.2010.11.008. [PMID: 21115097]
  • Nilusha Ragunathan, Julien Dairou, Elodie Sanfins, Florent Busi, Christophe Noll, Nathalie Janel, Jean-Marie Dupret, Fernando Rodrigues-Lima. Cadmium alters the biotransformation of carcinogenic aromatic amines by arylamine N-acetyltransferase xenobiotic-metabolizing enzymes: molecular, cellular, and in vivo studies. Environmental health perspectives. 2010 Dec; 118(12):1685-91. doi: 10.1289/ehp.1002334. [PMID: 20810355]
  • Michael A Campbell, Alyssa Gleichsner, Roxanne Alsbury, David Horvath, Jeffrey Suttle. The sprout inhibitors chlorpropham and 1,4-dimethylnaphthalene elicit different transcriptional profiles and do not suppress growth through a prolongation of the dormant state. Plant molecular biology. 2010 May; 73(1-2):181-9. doi: 10.1007/s11103-010-9607-6. [PMID: 20135197]
  • Moses S Owolabi, Labunmi Lajide, Matthew O Oladimeji, William N Setzer. The effect of essential oil formulations for potato sprout suppression. Natural product communications. 2010 Apr; 5(4):645-8. doi: ". [PMID: 20433090]
  • Pedro Henrique Viana de Carvalho, Vanessa de Menezes Prata, Péricles Barreto Alves, Sandro Navickiene. Determination of six pesticides in the medicinal herb Cordia salicifolia by matrix solid-phase dispersion and gas chromatography/mass spectrometry. Journal of AOAC International. 2009 Jul; 92(4):1184-9. doi: . [PMID: 19714988]
  • Pedro Henrique Viana de Carvalho, Alysson Santos Barreto, Marcelo O Rodrigues, Vanessa de Menezes Prata, Péricles Barreto Alves, Maria Eliane de Mesquita, Severino Alves, Sandro Navickiene. Two-dimensional coordination polymer matrix for solid-phase extraction of pesticide residues from plant Cordia salicifolia. Journal of separation science. 2009 Jun; 32(12):2132-8. doi: 10.1002/jssc.200900076. [PMID: 19479754]
  • Frances Orton, Ilka Lutz, Werner Kloas, Edwin J Routledge. Endocrine disrupting effects of herbicides and pentachlorophenol: in vitro and in vivo evidence. Environmental science & technology. 2009 Mar; 43(6):2144-50. doi: 10.1021/es8028928. [PMID: 19368227]
  • Dong-xian Liu, Jiang-nan He. [A study in extraction method of buprenorphine in urine]. Fa yi xue za zhi. 2007 Aug; 23(4):292-4. doi: NULL. [PMID: 17896524]
  • O Pigeon, P de Vos, J Potvin, K Thiry, D Villette, J-P Vandenberghe, B Huyghebaert, S Noel. Determination of chlorprophame residues in potatoes by GC-NPD or GC-MS. Communications in agricultural and applied biological sciences. 2005; 70(4):1079-82. doi: . [PMID: 16628958]
  • L Hautier, J-P Jansen, N Mabon, B Schiffers. Selectivity lists of pesticides to beneficial arthropods for IPM programs in carrot--first results. Communications in agricultural and applied biological sciences. 2005; 70(4):547-57. doi: ". [PMID: 16628889]
  • O Pigeon, N Ducat, L Demeulenaere, A Soete, E Somerhausen. Multi-residue method for determination of pesticides residues in potatoes by GC-NPD. Communications in agricultural and applied biological sciences. 2005; 70(4):1083-6. doi: ". [PMID: 16628959]
  • Haya Friedman, Jan W Vos, Peter K Hepler, Shimon Meir, Abraham H Halevy, Sonia Philosoph-Hadas. The role of actin filaments in the gravitropic response of snapdragon flowering shoots. Planta. 2003 Apr; 216(6):1034-42. doi: 10.1007/s00425-002-0957-4. [PMID: 12687372]
  • S Noël, B Huyghebaert, O Pigeon, B Weickmans, O Mostade. The heterogeneity of sprout inhibitor application with chlorpropham. Communications in agricultural and applied biological sciences. 2003; 68(4 Pt B):739-48. doi: . [PMID: 15151310]
  • S Noël, B Huyghebaert, O Pigeon, B Weickmans, O Mostade. Study of potatoes' sprout inhibitor treatments with chlorprophame. Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen). 2002; 67(3):431-9. doi: . [PMID: 12696410]
  • T Fujitani, Y Tada, A T Noguchi, M Yoneyama. Effects of chlorpropham (CIPC) on the hemopoietic system of rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 Mar; 39(3):253-9. doi: 10.1016/s0278-6915(00)00139-3. [PMID: 11278057]
  • J Franzaring, C Kempenaar, L J van der Eerden. Effects of vapours of chlorpropham and ethofumesate on wild plant species. Environmental pollution (Barking, Essex : 1987). 2001; 114(1):21-8. doi: 10.1016/s0269-7491(00)00205-0. [PMID: 11444003]
  • T Fujitani, Y Tada, A Fujii, M Kimura, M Yoneyama. Subchronic toxicity of chlorpropham (CIPC) in ICR mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2000 Jul; 38(7):617-25. doi: 10.1016/s0278-6915(00)00043-0. [PMID: 10942323]
  • J Holy. Chlorpropham [isopropyl N-(3-chlorophenyl) carbamate] disrupts microtubule organization, cell division, and early development of sea urchin embryos. Journal of toxicology and environmental health. Part A. 1998 Jun; 54(4):319-33. doi: 10.1080/009841098158872. [PMID: 9638902]
  • T Fujitani, Y Tada, A T Noguchi, M Yoneyama. Hemotoxicity of chlorpropham (CIPC) in F344 rats. Toxicology. 1997 Nov; 123(1-2):111-24. doi: 10.1016/s0300-483x(97)00113-3. [PMID: 9347926]
  • D J Lewis, S A Thorpe, S L Reynolds. The carry-through of residues of thiabendazole, tecnazene and chlorpropham from potatoes following manufacture into potato crisps and jacket potato crisps. Food additives and contaminants. 1996 Feb; 13(2):221-9. doi: 10.1080/02652039609374400. [PMID: 9064247]
  • B Liu, H C Joshi, B A Palevitz. Experimental manipulation of gamma-tubulin distribution in Arabidopsis using anti-microtubule drugs. Cell motility and the cytoskeleton. 1995; 31(2):113-29. doi: 10.1002/cm.970310204. [PMID: 7553905]
  • T S Dikshith, G Carrera, R B Raizada, S Mitjavila. Interaction of hexachlorocyclohexane (HCH) and chlorpropham (CIPC) in male rats. Toxicology letters. 1989 Feb; 45(2-3):281-8. doi: 10.1016/0378-4274(89)90019-2. [PMID: 2465584]
  • Y Fernandez, R A Boigegrain, C Cambon-Gros, P Deltour, S Mitjavila. Na+-coupled D-glucose uptake and membrane order of enterocyte brush border membrane vesicles, under the effect of a series of N-phenylcarbamates. FEBS letters. 1986 May; 201(1):119-23. doi: 10.1016/0014-5793(86)80582-8. [PMID: 3709801]
  • L Clayton, C W Lloyd. The relationship between the division plane and spindle geometry in Allium cells treated with CIPC and griseofulvin: an anti-tubulin study. European journal of cell biology. 1984 Jul; 34(2):248-53. doi: . [PMID: 6383831]
  • J L Wiedmann, G G Ecke, G G Still. Synthesis and isolation of 1-hydroxy-2-propyl 3-chlorocarbanilate from soybean plants treated with isopropyl 3-chlorocarbanilate. Journal of agricultural and food chemistry. 1976 May; 24(3):588-92. doi: 10.1021/jf60205a012. [PMID: 944727]
  • B Bajer-Rapic, E R Schmid, E Jünger, K Pollak. [Thin layer chromatographic separation and enzymatic detection of carbamate pesticides in plant extracts]. Die Nahrung. 1975; 19(7):551-5. doi: ". [PMID: 807848]
  • D L Brown, G B Bouck. Microtubule biogenesis and cell shape in Ochromonas. 3. Effects of herbicidal mitotic inhibitor isopropyl N-phenylcarbamate on shape and flagellum regeneration. The Journal of cell biology. 1974 May; 61(2):514-36. doi: 10.1083/jcb.61.2.514. [PMID: 4827911]
  • G G Still, E R Mansager. Metabolism of isopropyl-3-chlorocarbanilate by cucumber plants. Journal of agricultural and food chemistry. 1973 Sep; 21(5):787-91. doi: 10.1021/jf60189a006. [PMID: 4733369]
  • G J Van Esch, R Kroes. Long-term toxicity studies of chlorpropham and propham in mice and hamsters. Food and cosmetics toxicology. 1972 Jun; 10(3):373-81. doi: 10.1016/s0015-6264(72)80255-4. [PMID: 5065234]
  • G G Still, E R Mansager. Metabolism of isopropyl 3-chlorocarbanilate by soybean plants. Journal of agricultural and food chemistry. 1971 Sep; 19(5):879-84. doi: 10.1021/jf60177a049. [PMID: 5167433]