Chemical Formula: C10H12ClNO2
Chemical Formula C10H12ClNO2
Found 56 metabolite its formula value is C10H12ClNO2
Baclofen
Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. Baclofen stimulates GABA-B receptors leading to decreased frequency and amplitude of muscle spasms. It is especially useful in treating muscle spasticity associated with spinal cord injury. It appears to act primarily at the spinal cord level by inhibiting spinal polysynaptic afferent pathways and, to a lesser extent, monosynaptic afferent pathways. M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018755 - GABA Agonists D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist[1]. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].
Chlorpropham
D006133 - Growth Substances > D010937 - Plant Growth Regulators CONFIDENCE standard compound; INTERNAL_ID 2623 CONFIDENCE standard compound; INTERNAL_ID 8450 D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
Baclofen
M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018755 - GABA Agonists D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID B013; [MS2] KO008869 KEIO_ID B013 Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].
Methyl 2-amino-3-(4-chlorophenyl)propanoate
5-chloro-2-(3-methoxypropyl)pyridine-4-carbaldehyde
Carbamic acid,(3-chloro-4-methylphenyl)-, ethyl ester (9CI)
(4-Chloro-Phenyl)-Dimethylamino-Acetic Acid Hydrochloride
4-(1-Aminocyclopropyl)benzoic acid hydrochloride (1:1)
1H-Isoindole-1-carboxylic acid, 2,3-dihydro-, Methyl ester, hydrochloride
D-1,2,3,4-TETRAHYDROQUINOLINE-2-CARBOXYLIC ACID HYDROCHLORIDE
3-AMINO-3-(4-CHLORO-3-METHYL-PHENYL)-PROPIONIC ACID
(+)-Baclofen
C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant
1,2,3,4-TETRAHYDROQUINOLINE-2-CARBOXYLICACIDHYDROCHLORIDE
(3R)-1,2,3,4-tetrahydroisoquinolin-2-ium-3-carboxylate
1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid hydrochloride
L-1,2,3,4-TETRAHYDROQUINOLINE-2-CARBOXYLIC ACID HYDROCHLORIDE
Methyl 5-isoindolinecarboxylate hydrochloride (1:1)
1,2,3,4-TETRAHYDROISOQUINOLINE-7-CARBOXYLIC ACID HYDROCHLORIDE
7-METHOXY-2,3-DIHYDROISOQUINOLIN-4(1H)-ONE HYDROCHLORIDE
3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-
(S)-2-amino-3-(4-(chloromethyl)phenyl)propanoic acid
2-CHLORO-5-ETHYLPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid hydrochloride
chlorpropham
D006133 - Growth Substances > D010937 - Plant Growth Regulators D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
Arbaclofen
C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist[1].