Diisobutyl phthalate (BioDeep_00000002813)

 

Secondary id: BioDeep_00001873634

human metabolite Endogenous


代谢物信息卡片


1,2-Benzenedicarboxylic acid, 1,2-bis(2-methylpropyl) ester

化学式: C16H22O4 (278.1518012)
中文名称: 邻苯二甲酸二异丁酯
谱图信息: 最多检出来源 Homo sapiens(urine) 0.82%

分子结构信息

SMILES: CC(C)COC(=O)C1=C(C=CC=C1)C(=O)OCC(C)C
InChI: InChI=1S/C16H22O4/c1-11(2)9-19-15(17)13-7-5-6-8-14(13)16(18)20-10-12(3)4/h5-8,11-12H,9-10H2,1-4H3

描述信息

Di-(2-methylpropyl)-phthalate, also known as dibp or isobutyl phthalate, is a member of the class of compounds known as benzoic acid esters. Benzoic acid esters are ester derivatives of benzoic acid. Di-(2-methylpropyl)-phthalate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Di-(2-methylpropyl)-phthalate can be found in kohlrabi, which makes di-(2-methylpropyl)-phthalate a potential biomarker for the consumption of this food product. Di-(2-methylpropyl)-phthalate can be found primarily in urine. Di-(2-methylpropyl)-phthalate is a non-carcinogenic (not listed by IARC) potentially toxic compound. Phthalate esters are endocrine disruptors. Animal studies have shown that they disrupt reproductive development and can cause a number of malformations in affected young, such as reduced anogenital distance (AGD), cryptorchidism, hypospadias, and reduced fertility. The combination of effects associated with phthalates is called phthalate syndrome’ (A2883) (T3DB).
DIBP is an odorless plasticizer and has excellent heat and light stability. It is the lowest cost plasticizer for cellulose nitrate. DIBP has lower density and freezing point than DBP (dibutyl phthalate, CAS No.: 84-74-2). It has similar properties as dibutyl phthalate and can be used as a substitute for it.
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10016; ORIGINAL_PRECURSOR_SCAN_NO 10013
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10059; ORIGINAL_PRECURSOR_SCAN_NO 10056
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10032; ORIGINAL_PRECURSOR_SCAN_NO 10030
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10082; ORIGINAL_PRECURSOR_SCAN_NO 10080
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9953; ORIGINAL_PRECURSOR_SCAN_NO 9950
CONFIDENCE standard compound; INTERNAL_ID 1189; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9952; ORIGINAL_PRECURSOR_SCAN_NO 9950

同义名列表

32 个代谢物同义名

1,2-Benzenedicarboxylic acid, 1,2-bis(2-methylpropyl) ester; 1,2-Benzenedicarboxylate, 1,2-bis(2-methylpropyl) ester; 1,2-Benzenedicarboxylic acid, bis(2-methylpropyl) ester; 1,2-Benzenedicarboxylic acid, di(2-methylpropyl) ester; 1,2-Benzenedicarboxylic acid bis(2-methylpropyl) ester; 1,2-Benzenedicarboxylic acid di(2-methylpropyl) ester; 1,2-Benzenedicarboxylate bis(2-methylpropyl) ester; 1,2-bis(2-methylpropyl) benzene-1,2-dicarboxylate; 1,2-Benzenedicarboxylate di(2-methylpropyl) ester; Diisobutyl phthalate (acd/name 4.0); Bis(2-methylpropyl) phthalic acid; Di-(2-methylpropyl)-phthalic acid; Diisobutylester kyseliny ftalove; Di-2-methylpropyl phthalic acid; Phthalic acid, diisobutyl ester; Bis(2-methylpropyl) phthalate; di-(2-Methylpropyl)-phthalate; Di-2-methylpropyl phthalate; Phthalate, diisobutyl ester; Di-iso-butyl phthalic acid; Diisobutyl phthalic acid; Isobutyl-O-phthalic acid; Di(i-butyl)phthalic acid; Di-iso-butyl phthalate; Isobutyl phthalic acid; DIISOBUTYL PHTHALATE; Di(i-butyl)phthalate; Isobutyl-O-phthalate; Isobutyl phthalate; Hexaplas m/1b; Kodaflex dibp; DIBP



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

21 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jones B Graceli, Charles S da Costa, Mary J Laws, Ashley R K Deviney, Daryl Meling, Jodi A Flaws. Chronic exposure to a mixture of phthalates shifts the white and brown adipose tissue phenotype in female mice. Toxicological sciences : an official journal of the Society of Toxicology. 2023 Apr; ?(?):. doi: 10.1093/toxsci/kfad032. [PMID: 37021957]
  • Dan Zhang, Kai Zhou, Chenqi Liu, Xiujuan Li, Siyi Pan, Lan Zhong. Dissipation, uptake, translocation and accumulation of five phthalic acid esters in sediment-Zizania latifolia system. Chemosphere. 2023 Feb; 315(?):137651. doi: 10.1016/j.chemosphere.2022.137651. [PMID: 36584829]
  • M I Palacios-Arreola, A De Vizcaya-Ruiz, J Morales-Montor, O Amador-Muñoz. Toxicokinetic assessment of inhalatory absorption of Diisobutyl phthalate (DiBP) using a novel thermal desorption-GC-MS method to determine phthalate diesters in blood plasma. Environmental toxicology and pharmacology. 2022 Feb; 90(?):103813. doi: 10.1016/j.etap.2022.103813. [PMID: 35033683]
  • Thiago de Freitas, Joyce R Zapaterini, Cristiane M Moreira, Ariana M de Aquino, Luiz G Alonso-Costa, Lucas T Bidinotto, Laura Kass, Jodi A Flaws, Wellerson R Scarano, Luis F Barbisan. Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Oct; 156(?):112519. doi: 10.1016/j.fct.2021.112519. [PMID: 34428494]
  • Ling Huang, Xunzhi Zhu, Shixing Zhou, Zhenrui Cheng, Kai Shi, Chi Zhang, Hua Shao. Phthalic Acid Esters: Natural Sources and Biological Activities. Toxins. 2021 07; 13(7):. doi: 10.3390/toxins13070495. [PMID: 34357967]
  • Hui Chen, Kun Chen, Xuchun Qiu, Hai Xu, Guanghua Mao, Ting Zhao, Weiwei Feng, Emmanuel Sunday Okeke, Xiangyang Wu, Liuqing Yang. The reproductive toxicity and potential mechanisms of combined exposure to dibutyl phthalate and diisobutyl phthalate in male zebrafish (Danio rerio). Chemosphere. 2020 Nov; 258(?):127238. doi: 10.1016/j.chemosphere.2020.127238. [PMID: 32563064]
  • Seung-Hyun Jeong, Ji-Hun Jang, Hea-Young Cho, Yong-Bok Lee. Toxicokinetics of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rats: UPLC-ESI-MS/MS method development for the simultaneous determination of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rat plasma, urine, feces, and 11 various tissues collected from a toxicokinetic study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Nov; 145(?):111747. doi: 10.1016/j.fct.2020.111747. [PMID: 32926938]
  • Yong Li, Huangqian Yan, Qiyue Liu, Xiaoqing Li, Jing Ge, Xiangyang Yu. Accumulation and transport patterns of six phthalic acid esters (PAEs) in two leafy vegetables under hydroponic conditions. Chemosphere. 2020 Jun; 249(?):126457. doi: 10.1016/j.chemosphere.2020.126457. [PMID: 32220682]
  • Hanne Frederiksen, Ole Nielsen, Holger M Koch, Niels E Skakkebaek, Anders Juul, Niels Jørgensen, Anna-Maria Andersson. Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men; 2009-2017. International journal of hygiene and environmental health. 2020 01; 223(1):93-105. doi: 10.1016/j.ijheh.2019.10.002. [PMID: 31669154]
  • Kelly K Ferguson, Emma M Rosen, Zaira Rosario, Zlatan Feric, Antonia M Calafat, Thomas F McElrath, Carmen Vélez Vega, José F Cordero, Akram Alshawabkeh, John D Meeker. Environmental phthalate exposure and preterm birth in the PROTECT birth cohort. Environment international. 2019 11; 132(?):105099. doi: 10.1016/j.envint.2019.105099. [PMID: 31430608]
  • Hui Chen, Weiwei Feng, Kun Chen, Xuchun Qiu, Hai Xu, Guanghua Mao, Ting Zhao, Yangyang Ding, Xiangyang Wu. Transcriptomic analysis reveals potential mechanisms of toxicity in a combined exposure to dibutyl phthalate and diisobutyl phthalate in zebrafish (Danio rerio) ovary. Aquatic toxicology (Amsterdam, Netherlands). 2019 Nov; 216(?):105290. doi: 10.1016/j.aquatox.2019.105290. [PMID: 31518775]
  • Radwa Barakat, Talia Seymore, Po-Ching Patrick Lin, Chan Jin Park, CheMyong Jay Ko. Prenatal exposure to an environmentally relevant phthalate mixture disrupts testicular steroidogenesis in adult male mice. Environmental research. 2019 05; 172(?):194-201. doi: 10.1016/j.envres.2019.02.017. [PMID: 30802670]
  • Erin E Yost, Susan Y Euling, James A Weaver, Brandiese E J Beverly, Nagalakshmi Keshava, Anuradha Mudipalli, Xabier Arzuaga, Todd Blessinger, Laura Dishaw, Andrew Hotchkiss, Susan L Makris. Hazards of diisobutyl phthalate (DIBP) exposure: A systematic review of animal toxicology studies. Environment international. 2019 04; 125(?):579-594. doi: 10.1016/j.envint.2018.09.038. [PMID: 30591249]
  • Luísa Correia-Sá, Monika Kasper-Sonnenberg, Claudia Pälmke, André Schütze, Sónia Norberto, Conceição Calhau, Valentina F Domingues, Holger M Koch. Obesity or diet? Levels and determinants of phthalate body burden - A case study on Portuguese children. International journal of hygiene and environmental health. 2018 04; 221(3):519-530. doi: 10.1016/j.ijheh.2018.02.001. [PMID: 29454883]
  • Munawar Hussain Soomro, Nour Baiz, Claire Philippat, Celine Vernet, Valerie Siroux, Cara Nichole Maesano, Shreosi Sanyal, Remy Slama, Carl-Gustaf Bornehag, Isabella Annesi-Maesano. Prenatal Exposure to Phthalates and the Development of Eczema Phenotypes in Male Children: Results from the EDEN Mother-Child Cohort Study. Environmental health perspectives. 2018 02; 126(2):027002. doi: 10.1289/ehp1829. [PMID: 29398652]
  • Yitao Pan, Xiaoyang Wang, Leo W Y Yeung, Nan Sheng, Qianqian Cui, Ruina Cui, Hongxia Zhang, Jiayin Dai. Dietary exposure to di-isobutyl phthalate increases urinary 5-methyl-2'-deoxycytidine level and affects reproductive function in adult male mice. Journal of environmental sciences (China). 2017 Nov; 61(?):14-23. doi: 10.1016/j.jes.2017.04.036. [PMID: 29191310]
  • Anika Engel, Thorsten Buhrke, Francine Imber, Sönke Jessel, Albrecht Seidel, Wolfgang Völkel, Alfonso Lampen. Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR. Toxicology letters. 2017 Aug; 277(?):54-63. doi: 10.1016/j.toxlet.2017.05.028. [PMID: 28571686]
  • Zhihuan Zhang, Tiantian Wan, Xuyang Peng, Guangxiu He, Yu Liu, Li Zeng. Distribution and sources of oxygenated non-hydrocarbons in topsoil of Beijing, China. Environmental science and pollution research international. 2016 Aug; 23(16):16524-41. doi: 10.1007/s11356-016-6790-2. [PMID: 27172982]
  • Ning Liu, Fuling Wen, Fengmin Li, Xiang Zheng, Zhi Liang, Hao Zheng. Inhibitory mechanism of phthalate esters on Karenia brevis. Chemosphere. 2016 Jul; 155(?):498-508. doi: 10.1016/j.chemosphere.2016.04.082. [PMID: 27151426]
  • Lauren E Johns, Glinda S Cooper, Audrey Galizia, John D Meeker. Exposure assessment issues in epidemiology studies of phthalates. Environment international. 2015 Dec; 85(?):27-39. doi: 10.1016/j.envint.2015.08.005. [PMID: 26313703]
  • Xiping Cui, Panpan Wu, Dan Lai, Shengwu Zheng, Yingshan Chen, Sergei A Eremin, Wei Peng, Suqing Zhao. Development of a Highly Specific Fluorescence Immunoassay for Detection of Diisobutyl Phthalate in Edible Oil Samples. Journal of agricultural and food chemistry. 2015 Oct; 63(42):9372-8. doi: 10.1021/acs.jafc.5b03922. [PMID: 26449794]
  • Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Feb; 143(2):333-48. doi: 10.1093/toxsci/kfu231. [PMID: 25349334]
  • Bin Wang, Hexing Wang, Wei Zhou, Yue Chen, Ying Zhou, Qingwu Jiang. Urinary excretion of phthalate metabolites in school children of China: implication for cumulative risk assessment of phthalate exposure. Environmental science & technology. 2015 Jan; 49(2):1120-9. doi: 10.1021/es504455a. [PMID: 25496010]
  • Ulla Nordström Joensen, Niels Jørgensen, Michael Meldgaard, Hanne Frederiksen, Anna-Maria Andersson, Torkil Menné, Jeanne Duus Johansen, Berit Christina Carlsen, Steen Stender, Pal Bela Szecsi, Niels Erik Skakkebæk, Ewa Rajpert-De Meyts, Jacob P Thyssen. Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men. Environmental health perspectives. 2014 Apr; 122(4):345-50. doi: 10.1289/ehp.1306720. [PMID: 24380925]
  • Wolfgang Völkel, Mandy Kiranoglu, Ralph Schuster, Hermann Fromme. Phthalate intake by infants calculated from biomonitoring data. Toxicology letters. 2014 Mar; 225(2):222-9. doi: 10.1016/j.toxlet.2013.12.012. [PMID: 24374175]
  • Yan Niu, Shu-Fang Wang. [A new phthalide from angelicae sinensis radix]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2014 Jan; 39(1):80-2. doi: . [PMID: 24754173]
  • Selma K Kranich, Hanne Frederiksen, Anna-Maria Andersson, Niels Jørgensen. Estimated daily intake and hazard quotients and indices of phthtalate diesters for young danish men. Environmental science & technology. 2014; 48(1):706-12. doi: 10.1021/es402569k. [PMID: 24228837]
  • V Guazzotti, A Marti, L Piergiovanni, S Limbo. Bio-based coatings as potential barriers to chemical contaminants from recycled paper and board for food packaging. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2014; 31(3):402-13. doi: 10.1080/19440049.2013.869360. [PMID: 24279457]
  • Matthew Lorber, Holger M Koch. Development and application of simple pharmacokinetic models to study human exposure to di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP). Environment international. 2013 Sep; 59(?):469-77. doi: 10.1016/j.envint.2013.07.010. [PMID: 23955327]
  • Anna Pereira-Fernandes, Heidi Demaegdt, Karine Vandermeiren, Tine L M Hectors, Philippe G Jorens, Ronny Blust, Caroline Vanparys. Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect. PloS one. 2013; 8(10):e77481. doi: 10.1371/journal.pone.0077481. [PMID: 24155963]
  • H M Koch, K L Y Christensen, V Harth, M Lorber, T Brüning. Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses. Archives of toxicology. 2012 Dec; 86(12):1829-39. doi: 10.1007/s00204-012-0908-1. [PMID: 22820759]
  • PingGu Wu, DaJin Yang, Liqun Zhang, XiangHong Shen, XiaoDong Pan, LiYuan Wang, Jing Zhang, Ying Tan, Liang Feng, Ying Ying. Simultaneous determination of 17 phthalate esters in edible vegetable oils by GC-MS with silica/PSA-mixed solid-phase extraction. Journal of separation science. 2012 Nov; 35(21):2932-9. doi: 10.1002/jssc.201200462. [PMID: 23065997]
  • Mei-Xian Xiang, Ya-Jing Hu, Yun-Jun Yan. [Study on chemical composition of ethylacetate fraction from Polygonum amplexicaule var. sinense]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Oct; 35(10):1610-4. doi: . [PMID: 23627126]
  • Xia Li, Junying Zhang, Wenyuan Gao, Haiyang Wang. Study on chemical composition, anti-inflammatory and anti-microbial activities of extracts from Chinese pear fruit (Pyrus bretschneideri Rehd.). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Oct; 50(10):3673-9. doi: 10.1016/j.fct.2012.07.019. [PMID: 22824088]
  • T Søeborg, H Frederiksen, A M Andersson. Cumulative risk assessment of phthalate exposure of Danish children and adolescents using the hazard index approach. International journal of andrology. 2012 Jun; 35(3):245-52. doi: 10.1111/j.1365-2605.2011.01240.x. [PMID: 22320716]
  • Robin M Whyatt, Xinhua Liu, Virginia A Rauh, Antonia M Calafat, Allan C Just, Lori Hoepner, Diurka Diaz, James Quinn, Jennifer Adibi, Frederica P Perera, Pam Factor-Litvak. Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age. Environmental health perspectives. 2012 Feb; 120(2):290-5. doi: 10.1289/ehp.1103705. [PMID: 21893441]
  • Thomas Göen, Lorenz Dobler, Jan Koschorreck, Johannes Müller, Gerhard Andreas Wiesmüller, Hans Drexler, Marike Kolossa-Gehring. Trends of the internal phthalate exposure of young adults in Germany--follow-up of a retrospective human biomonitoring study. International journal of hygiene and environmental health. 2011 Dec; 215(1):36-45. doi: 10.1016/j.ijheh.2011.07.011. [PMID: 21889907]
  • Holger M Koch, Matthias Wittassek, Thomas Brüning, Jürgen Angerer, Ursel Heudorf. Exposure to phthalates in 5-6 years old primary school starters in Germany--a human biomonitoring study and a cumulative risk assessment. International journal of hygiene and environmental health. 2011 Jun; 214(3):188-95. doi: 10.1016/j.ijheh.2011.01.009. [PMID: 21371937]
  • Justin A Colacino, Amr S Soliman, Antonia M Calafat, Muna S Nahar, Adrienne Van Zomeren-Dohm, Ahmed Hablas, Ibrahim A Seifeldin, Laura S Rozek, Dana C Dolinoy. Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study. Environmental health : a global access science source. 2011 May; 10(?):40. doi: 10.1186/1476-069x-10-40. [PMID: 21575223]
  • Susana Lin, Hsiu-Ying Ku, Pen-Hua Su, Jein-Wen Chen, Po-Chin Huang, Jürgen Angerer, Shu-Li Wang. Phthalate exposure in pregnant women and their children in central Taiwan. Chemosphere. 2011 Feb; 82(7):947-55. doi: 10.1016/j.chemosphere.2010.10.073. [PMID: 21075419]
  • Guohui Li, Qingwen Zhang, Yitao Wang. [Chemical constituents from roots of Pueraria lobata]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Dec; 35(23):3156-60. doi: . [PMID: 21355238]
  • Tong Bu, Ming Liu, Lanhong Zheng, Yuewei Guo, Xiukun Lin. α-Glucosidase inhibition and the in vivo hypoglycemic effect of butyl-isobutyl-phthalate derived from the Laminaria japonica rhizoid. Phytotherapy research : PTR. 2010 Nov; 24(11):1588-91. doi: 10.1002/ptr.3139. [PMID: 21031613]
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  • John D Meeker, Howard Hu, David E Cantonwine, Hector Lamadrid-Figueroa, Antonia M Calafat, Adrienne S Ettinger, Mauricio Hernandez-Avila, Rita Loch-Caruso, Martha María Téllez-Rojo. Urinary phthalate metabolites in relation to preterm birth in Mexico city. Environmental health perspectives. 2009 Oct; 117(10):1587-92. doi: 10.1289/ehp.0800522. [PMID: 20019910]
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  • Elcim Seckin, Hermann Fromme, Wolfgang Völkel. Determination of total and free mono-n-butyl phthalate in human urine samples after medication of a di-n-butyl phthalate containing capsule. Toxicology letters. 2009 Jul; 188(1):33-7. doi: 10.1016/j.toxlet.2009.03.002. [PMID: 19433267]
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