METHYLAMINE (BioDeep_00000268066)
Main id: BioDeep_00000004397
PANOMIX_OTCML-2023
代谢物信息卡片
METHYLAMINE
化学式: CH5N (31.042197)
中文名称: 氨基甲烷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN
InChI: InChI=1S/CH5N/c1-2/h2H2,1H3
描述信息
The simplest of the methylamines, consisting of ammonia bearing a single methyl substituent.
同义名列表
2 个代谢物同义名
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:16830
- KEGG: C00218
- PubChem: 6329
- DrugBank: DB01828
- ChEMBL: CHEMBL43280
- KNApSAcK: C00050483
- CAS: 74-89-5
- MoNA: HMDB0000164_ms_ms_262
- MoNA: HMDB0000164_ms_ms_260
- MoNA: HMDB0000164_ms_ms_261
- MetaboLights: MTBLC16830
- PubChem: 3518
- PDB-CCD: NME
- 3DMET: B00060
- NIKKAJI: J1.431A
- RefMet: Methylamine
- KNApSAcK: 16830
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Georges Jourdi, Johan Abdoul, Virginie Siguret, Xavier Decleves, Elisa Frezza, Claire Pailleret, Isabelle Gouin-Thibault, Sophie Gandrille, Nathalie Neveux, Charles Marc Samama, Samuela Pasquali, Pascale Gaussem. Induced forms of α2-macroglobulin neutralize heparin and direct oral anticoagulant effects.
International journal of biological macromolecules.
2021 Aug; 184(?):209-217. doi:
10.1016/j.ijbiomac.2021.06.058. [PMID: 34126147] - Mansoore Esmaili, Brian P Tancowny, Xiongyao Wang, Audric Moses, Leonardo M Cortez, Valerie L Sim, Holger Wille, Michael Overduin. Native nanodiscs formed by styrene maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids.
The Journal of biological chemistry.
2020 06; 295(25):8460-8469. doi:
10.1074/jbc.ra119.012348. [PMID: 32358064] - Wahiduzzaman, Md Imtaiyaz Hassan, Asimul Islam, Faizan Ahmad. Urea Stress: Myo-inositol's efficacy to counteract destabilization of TIM-β-globin complex by urea is as good as that of the methylamine.
International journal of biological macromolecules.
2020 May; 151(?):1108-1115. doi:
10.1016/j.ijbiomac.2019.10.153. [PMID: 31751698] - Pascal Ganz, Toyosi Ijato, Romano Porras-Murrilo, Nils Stührwohldt, Uwe Ludewig, Benjamin Neuhäuser. A twin histidine motif is the core structure for high-affinity substrate selection in plant ammonium transporters.
The Journal of biological chemistry.
2020 03; 295(10):3362-3370. doi:
10.1074/jbc.ra119.010891. [PMID: 31988244] - Dorna Davani-Davari, Iman Karimzadeh, Shahrokh Ezzatzadegan-Jahromi, Mohammad Mahdi Sagheb. Potential Adverse Effects of Creatine Supplement on the Kidney in Athletes and Bodybuilders.
Iranian journal of kidney diseases.
2018 10; 12(5):253-260. doi:
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Rapid communications in mass spectrometry : RCM.
2018 Aug; 32(16):1439-1450. doi:
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Chinese journal of natural medicines.
2018 Apr; 16(4):261-270. doi:
10.1016/s1875-5364(18)30056-6. [PMID: 29703326] - Haoxin Lv, Nurettin Sahin, Akio Tani. Isolation and genomic characterization of Novimethylophilus kurashikiensis gen. nov. sp. nov., a new lanthanide-dependent methylotrophic species of Methylophilaceae.
Environmental microbiology.
2018 03; 20(3):1204-1223. doi:
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Protoplasma.
2017 Sep; 254(5):1973-1981. doi:
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Plant physiology and biochemistry : PPB.
2016 Nov; 108(?):99-108. doi:
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Microbes and environments.
2016 Sep; 31(3):268-78. doi:
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Analytical chemistry.
2016 09; 88(18):8965-71. doi:
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Biochimica et biophysica acta.
2016 Aug; 1861(8 Pt A):703-14. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Jul; 1025(?):68-75. doi:
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European journal of pharmacology.
2016 Jun; 781(?):181-9. doi:
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International journal of biological macromolecules.
2016 Feb; 83(?):366-75. doi:
10.1016/j.ijbiomac.2015.11.043. [PMID: 26608004] - Safikur Rahman, Marina Warepam, Laishram R Singh, Tanveer Ali Dar. A current perspective on the compensatory effects of urea and methylamine on protein stability and function.
Progress in biophysics and molecular biology.
2015 Nov; 119(2):129-36. doi:
10.1016/j.pbiomolbio.2015.06.002. [PMID: 26095775] - Kosuke Shiraishi, Masahide Oku, Daichi Uchida, Hiroya Yurimoto, Yasuyoshi Sakai. Regulation of nitrate and methylamine metabolism by multiple nitrogen sources in the methylotrophic yeast Candida boidinii.
FEMS yeast research.
2015 Nov; 15(7):. doi:
10.1093/femsyr/fov084. [PMID: 26377403] - Phattara Boraphech, Paitip Thiravetyan. Removal of trimethylamine (fishy odor) by C₃ and CAM plants.
Environmental science and pollution research international.
2015 Aug; 22(15):11543-57. doi:
10.1007/s11356-015-4364-3. [PMID: 25827651] - Tingting Wei, Liangcai Zhao, Jianmin Jia, Huanhuan Xia, Yao Du, Qiuting Lin, Xiaodong Lin, Xinjian Ye, Zhihan Yan, Hongchang Gao. Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice.
Scientific reports.
2015 Jul; 5(?):11998. doi:
10.1038/srep11998. [PMID: 26149603] - Sha-Sha Lv, Yi-Rong Liu, Teng Huang, Ya-Juan Feng, Shuai Jiang, Wei Huang. Stability of Hydrated Methylamine: Structural Characteristics and H2N···H-O Hydrogen Bonds.
The journal of physical chemistry. A.
2015 Apr; 119(16):3770-9. doi:
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Scientific reports.
2015 Apr; 5(?):9719. doi:
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Chemistry (Weinheim an der Bergstrasse, Germany).
2015 Mar; 21(12):4789-99. doi:
10.1002/chem.201405967. [PMID: 25678406] - Safikur Rahman, Md Tabish Rehman, Laishram R Singh, Marina Warepam, Faizan Ahmad, Tanveer Ali Dar. Salt potentiates methylamine counteraction system to offset the deleterious effects of urea on protein stability and function.
PloS one.
2015; 10(3):e0119597. doi:
10.1371/journal.pone.0119597. [PMID: 25793733] - Ioana Alesutan, Katharina Musculus, Tatsiana Castor, Kousi Alzoubi, Jakob Voelkl, Florian Lang. Inhibition of Phosphate-Induced Vascular Smooth Muscle Cell Osteo-/Chondrogenic Signaling and Calcification by Bafilomycin A1 and Methylamine.
Kidney & blood pressure research.
2015; 40(5):490-9. doi:
10.1159/000368524. [PMID: 26418500] - Wen-Hsiao Chuang, Ping-Chung Liu, Chia-Yu Hung, Kuo-Kau Lee. Purification, characterization and molecular cloning of alpha-2-macroglobulin in cobia, Rachycentron canadum.
Fish & shellfish immunology.
2014 Dec; 41(2):346-55. doi:
10.1016/j.fsi.2014.09.016. [PMID: 25245622] - Majid Rezayi, Reza Karazhian, Yadollah Abdollahi, Leila Narimani, Seyedeh Belin Tavakoly Sany, Saeid Ahmadzadeh, Yatimah Alias. Titanium (III) cation selective electrode based on synthesized tris(2pyridyl) methylamine ionophore and its application in water samples.
Scientific reports.
2014 Apr; 4(?):4664. doi:
10.1038/srep04664. [PMID: 24722576] - Yan Zhu, Xiao-Min Ge, Mi-Mi Wu, Xuan Li, Jun-Min He. The role and interactions of cytosolic alkalization and hydrogen peroxide in ultraviolet B-induced stomatal closure in Arabidopsis.
Plant science : an international journal of experimental plant biology.
2014 Feb; 215-216(?):84-90. doi:
10.1016/j.plantsci.2013.11.010. [PMID: 24388518] - Mélanie Boeckstaens, Elisa Llinares, Pascale Van Vooren, Anna Maria Marini. The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein.
Nature communications.
2014; 5(?):3101. doi:
10.1038/ncomms4101. [PMID: 24476960] - Libo Li, Igor Vorobyov, Toby W Allen. The different interactions of lysine and arginine side chains with lipid membranes.
The journal of physical chemistry. B.
2013 Oct; 117(40):11906-20. doi:
10.1021/jp405418y. [PMID: 24007457] - Inga Rempe, Ulrike Brezina, Susanne Kersten, Sven Dänicke. Effects of a Fusarium toxin-contaminated maize treated with sodium metabisulphite, methylamine and calcium hydroxide in diets for female piglets.
Archives of animal nutrition.
2013 Aug; 67(4):314-29. doi:
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Protein and peptide letters.
2013 Jan; 20(1):61-70. doi:
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PloS one.
2013; 8(9):e72533. doi:
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Microbial ecology.
2013 Jan; 65(1):180-96. doi:
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Analytica chimica acta.
2012 Nov; 752(?):106-11. doi:
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Journal of ethnopharmacology.
2012 Aug; 142(3):647-56. doi:
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International immunopharmacology.
2011 Aug; 11(8):1079-89. doi:
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2011 Jan; 25(1):26-7. doi:
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American journal of physiology. Cell physiology.
2010 Sep; 299(3):C695-705. doi:
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Experimental physiology.
2010 Sep; 95(9):926-37. doi:
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Plant, cell & environment.
2010 Jun; 33(6):1049-56. doi:
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2010 May; 25(5):1608-13. doi:
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2010 Jan; 5(1):e8921. doi:
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2009 May; 27(7):759-66. doi:
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2009; 462(?):59-74. doi:
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Analytical biochemistry.
2009 Jan; 384(1):20-6. doi:
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Analytical chemistry.
2008 Oct; 80(19):7248-56. doi:
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Plant physiology.
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Journal of the American Society of Nephrology : JASN.
2006 Sep; 17(9):2414-23. doi:
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Genetics.
2006 Aug; 173(4):2005-19. doi:
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Plant biology (Stuttgart, Germany).
2006 Jul; 8(4):522-8. doi:
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The Biochemical journal.
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Clinica chimica acta; international journal of clinical chemistry.
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The American journal of pathology.
2006 Mar; 168(3):718-26. doi:
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Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.
2006 Mar; 13(1-2):65-9. doi:
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2006 Mar; 13(1-2):103-10. doi:
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Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.
2006 Mar; 13(1-2):147-53. doi:
10.1016/j.tracli.2006.03.005. [PMID: 16580864] - An Van Nuland, Patrick Vandormael, Monica Donaton, Marta Alenquer, Artur Lourenço, Edgar Quintino, Matthias Versele, Johan M Thevelein. Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast.
Molecular microbiology.
2006 Mar; 59(5):1485-505. doi:
10.1111/j.1365-2958.2005.05043.x. [PMID: 16468990] - Annette Kiewietdejonge, Matthew Pitts, Lee Cabuhat, Claire Sherman, Wipapat Kladwang, Gena Miramontes, Jorge Floresvillar, Jeffrey Chan, Robert M Ramirez. Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae.
FEMS yeast research.
2006 Mar; 6(2):205-17. doi:
10.1111/j.1567-1364.2006.00030.x. [PMID: 16487344] - Maria Mayer, Gabriel Schaaf, Isabelle Mouro, Claude Lopez, Yves Colin, Petra Neumann, Jean-Pierre Cartron, Uwe Ludewig. Different transport mechanisms in plant and human AMT/Rh-type ammonium transporters.
The Journal of general physiology.
2006 Feb; 127(2):133-44. doi:
10.1085/jgp.200509369. [PMID: 16446503] - Mar Hernandez, Montse Solé, Mercè Boada, Mercedes Unzeta. Soluble semicarbazide sensitive amine oxidase (SSAO) catalysis induces apoptosis in vascular smooth muscle cells.
Biochimica et biophysica acta.
2006 Feb; 1763(2):164-73. doi:
10.1016/j.bbamcr.2005.11.017. [PMID: 16448709] - Don-On Daniel Mak, Binh Dang, I David Weiner, J Kevin Foskett, Connie M Westhoff. Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG.
American journal of physiology. Renal physiology.
2006 Feb; 290(2):F297-305. doi:
10.1152/ajprenal.00147.2005. [PMID: 16131648] - Laura Cioni, Gaetano De Siena, Carla Ghelardini, Olivia Sernissi, Chiara Alfarano, Renato Pirisino, Laura Raimondi. Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: interactive effects with methylamine and alpha-aminoguanidine.
European journal of pharmacology.
2006 Jan; 529(1-3):179-87. doi:
10.1016/j.ejphar.2005.10.052. [PMID: 16325802] - Nedjma Zidi-Yahiaoui, Isabelle Mouro-Chanteloup, Anne-Marie D'Ambrosio, Claude Lopez, Pierre Gane, Caroline Le van Kim, Jean-Pierre Cartron, Yves Colin, Pierre Ripoche. Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells.
The Biochemical journal.
2005 Oct; 391(Pt 1):33-40. doi:
10.1042/bj20050657. [PMID: 15929723] - Jacques R Poortmans, Alain Kumps, Pierre Duez, Aline Fofonka, Alain Carpentier, Marc Francaux. Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate.
Medicine and science in sports and exercise.
2005 Oct; 37(10):1717-20. doi:
10.1249/01.mss.0000176398.64189.e6. [PMID: 16260971] - Mary E Handlogten, Seong-Pyo Hong, Connie M Westhoff, I David Weiner. Apical ammonia transport by the mouse inner medullary collecting duct cell (mIMCD-3).
American journal of physiology. Renal physiology.
2005 Aug; 289(2):F347-58. doi:
10.1152/ajprenal.00253.2004. [PMID: 15798090] - Kwang-Seo Kim, Eithne Feild, Natalie King, Takuro Yaoi, Sydney Kustu, William Inwood. Spontaneous mutations in the ammonium transport gene AMT4 of Chlamydomonas reinhardtii.
Genetics.
2005 Jun; 170(2):631-44. doi:
10.1534/genetics.105.041574. [PMID: 15802504] - Joseph M Mettenburg, Sanja Arandjelovic, Steven L Gonias. A chemically modified preparation of alpha2-macroglobulin binds beta-amyloid peptide with increased affinity and inhibits Abeta cytotoxicity.
Journal of neurochemistry.
2005 Apr; 93(1):53-62. doi:
10.1111/j.1471-4159.2004.02995.x. [PMID: 15773905] - Dominique Loqué, Uwe Ludewig, Lixing Yuan, Nicolaus von Wirén. Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole.
Plant physiology.
2005 Feb; 137(2):671-80. doi:
10.1104/pp.104.051268. [PMID: 15665250] - Mariko Tachikawa, Takashi Aburada, Masakatsu Tezuka, Ryoji Sawamura. Occurrence and production of chloramines in the chlorination of creatinine in aqueous solution.
Water research.
2005 Jan; 39(2-3):371-9. doi:
10.1016/j.watres.2004.09.029. [PMID: 15644245] - Nazih L Nakhoul, Hendrik Dejong, Solange M Abdulnour-Nakhoul, Emile L Boulpaep, Kathleen Hering-Smith, L Lee Hamm. Characteristics of renal Rhbg as an NH4(+) transporter.
American journal of physiology. Renal physiology.
2005 Jan; 288(1):F170-81. doi:
10.1152/ajprenal.00419.2003. [PMID: 15353405] - Pierre Ripoche, Olivier Bertrand, Pierre Gane, Connie Birkenmeier, Yves Colin, Jean-Pierre Cartron. Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.
Proceedings of the National Academy of Sciences of the United States of America.
2004 Dec; 101(49):17222-7. doi:
10.1073/pnas.0403704101. [PMID: 15572441] - Isabel Velasco, Sandra Tenreiro, Isabel L Calderon, Bruno André. Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.
Eukaryotic cell.
2004 Dec; 3(6):1492-503. doi:
10.1128/ec.3.6.1492-1503.2004. [PMID: 15590823] - Claire Hunter-Lavin, Emma L Davies, Maria M F V G Bacelar, Michael J Marshall, Sarah M Andrew, John H H Williams. Hsp70 release from peripheral blood mononuclear cells.
Biochemical and biophysical research communications.
2004 Nov; 324(2):511-7. doi:
10.1016/j.bbrc.2004.09.075. [PMID: 15474457] - Philippe Jourand, Eric Giraud, Gilles Béna, Abdoulaye Sy, Anne Willems, Monique Gillis, Bernard Dreyfus, Philippe de Lajudie. Methylobacterium nodulans sp. nov., for a group of aerobic, facultatively methylotrophic, legume root-nodule-forming and nitrogen-fixing bacteria.
International journal of systematic and evolutionary microbiology.
2004 Nov; 54(Pt 6):2269-2273. doi:
10.1099/ijs.0.02902-0. [PMID: 15545469] - Hui Li, Wenhong Luo, Jijin Lin, Zhexuan Lin, Yuan Zhang. Assay of plasma semicarbazide-sensitive amine oxidase and determination of its endogenous substrate methylamine by liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Oct; 810(2):277-82. doi:
10.1016/j.jchromb.2004.08.011. [PMID: 15380725] - Mary E Handlogten, Seong-Pyo Hong, Connie M Westhoff, I David Weiner. Basolateral ammonium transport by the mouse inner medullary collecting duct cell (mIMCD-3).
American journal of physiology. Renal physiology.
2004 Oct; 287(4):F628-38. doi:
10.1152/ajprenal.00363.2003. [PMID: 15149971] - Uwe Ludewig. Electroneutral ammonium transport by basolateral rhesus B glycoprotein.
The Journal of physiology.
2004 Sep; 559(Pt 3):751-9. doi:
10.1113/jphysiol.2004.067728. [PMID: 15284342] - Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J Steven Richardson, Peter H Yu. Protein cross-linkage induced by formaldehyde derived from semicarbazide-sensitive amine oxidase-mediated deamination of methylamine.
The Journal of pharmacology and experimental therapeutics.
2004 Sep; 310(3):1125-32. doi:
10.1124/jpet.104.068601. [PMID: 15128865] - Quirine Lisman, Dorothy Urli-Stam, Joost C M Holthuis. HOR7, a multicopy suppressor of the Ca2+-induced growth defect in sphingolipid mannosyltransferase-deficient yeast.
The Journal of biological chemistry.
2004 Aug; 279(35):36390-6. doi:
10.1074/jbc.m406197200. [PMID: 15208314] - Hani Boshra, Andrew E Gelman, J Oriol Sunyer. Structural and functional characterization of complement C4 and C1s-like molecules in teleost fish: insights into the evolution of classical and alternative pathways.
Journal of immunology (Baltimore, Md. : 1950).
2004 Jul; 173(1):349-59. doi:
10.4049/jimmunol.173.1.349. [PMID: 15210793] - Yu-Lun Tseng, Wen-Bin Wu, Chun-Chieh Hsu, Hui-Chin Peng, Tur-Fu Huang. Inhibitory effects of human alpha2-macroglobulin and mouse serum on the PSGL-1 and glycoprotein Ib proteolysis by a snake venom metalloproteinase, triflamp.
Toxicon : official journal of the International Society on Toxinology.
2004 Jun; 43(7):769-77. doi:
10.1016/j.toxicon.2004.03.006. [PMID: 15284011] - Amanda M Munson, Devon H Haydon, Sherie L Love, Gillian L Fell, Vikram R Palanivel, Anne G Rosenwald. Yeast ARL1 encodes a regulator of K+ influx.
Journal of cell science.
2004 May; 117(Pt 11):2309-20. doi:
10.1242/jcs.01050. [PMID: 15126631] - Craig M Stolen, Rami Madanat, Luc Marti, Seppo Kari, Gennady G Yegutkin, Hannu Sariola, Antonio Zorzano, Sirpa Jalkanen. Semicarbazide sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes-like complications.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2004 Apr; 18(6):702-4. doi:
10.1096/fj.03-0562fje. [PMID: 14977883] - Sigrun Lange, Alister W Dodds, Bergljót Magnadóttir. Isolation and characterization of complement component C3 from Atlantic cod (Gadus morhua L.) and Atlantic halibut (Hippoglossus hippoglossus L.).
Fish & shellfish immunology.
2004 Feb; 16(2):227-39. doi:
10.1016/s1050-4648(03)00081-0. [PMID: 15123326] - Georgia I Anyatonwu, Edmond D Buck, Barbara E Ehrlich. Methanethiosulfonate ethylammonium block of amine currents through the ryanodine receptor reveals single pore architecture.
The Journal of biological chemistry.
2003 Nov; 278(46):45528-38. doi:
10.1074/jbc.m307863200. [PMID: 12963712] - Uwe Ludewig, Stephanie Wilken, Binghua Wu, Wolfgang Jost, Petr Obrdlik, Mohamed El Bakkoury, Anne-Marie Marini, Bruno André, Tanja Hamacher, Eckhard Boles, Nicolaus von Wirén, Wolf B Frommer. Homo- and hetero-oligomerization of ammonium transporter-1 NH4 uniporters.
The Journal of biological chemistry.
2003 Nov; 278(46):45603-10. doi:
10.1074/jbc.m307424200. [PMID: 12952951]