Roseoflavin (BioDeep_00000002586)

   


代谢物信息卡片


8-Dimethylaminoriboflavin

化学式: C18H23N5O6 (405.1648)
中文名称:
谱图信息: 最多检出来源 Macaca mulatta(lipidsearch) 36.04%

分子结构信息

SMILES: c1(c(cc2c(c1)n(c1c(n2)c(=O)[nH]c(=O)n1)C[C@H]([C@H](O)[C@H](O)CO)O)C)N(C)C
InChI: InChI=1S/C18H23N5O6/c1-8-4-9-11(5-10(8)22(2)3)23(6-12(25)15(27)13(26)7-24)16-14(19-9)17(28)21-18(29)20-16/h4-5,12-13,15,24-27H,6-7H2,1-3H3,(H,21,28,29)/t12-,13+,15-/m0/s1

描述信息

A benzopteridine that is riboflavin in which the methyl group at position 8 is substituted by a dimethylamino group.

同义名列表

3 个代谢物同义名

Roseoflavin; 8-Dimethylaminoriboflavin; Roseoflavine



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CAT, DAO, GCH1, REXO2, RFK
Peripheral membrane protein 1 DAO
Endosome membrane 1 TF
Nucleus 3 ACD, GCH1, REXO2
cytosol 5 CAT, DAO, GCH1, GSR, RFK
nuclear body 1 ACD
nucleoplasm 2 ACD, GCH1
Cell membrane 1 DAO
cell surface 1 TF
Cytoplasm, cytosol 1 DAO
plasma membrane 2 DAO, TF
presynaptic active zone 1 DAO
Membrane 1 CAT
apical plasma membrane 1 TF
extracellular exosome 4 CAT, DAO, GSR, TF
extracellular space 2 DAO, TF
perinuclear region of cytoplasm 1 TF
bicellular tight junction 1 DAO
mitochondrion 5 CAT, GCH1, GSR, REXO2, RFK
protein-containing complex 2 CAT, GCH1
intracellular membrane-bounded organelle 1 CAT
Secreted 2 DAO, TF
extracellular region 3 CAT, DAO, TF
basal part of cell 1 TF
Mitochondrion matrix 1 REXO2
mitochondrial matrix 3 CAT, GSR, REXO2
Extracellular side 1 DAO
nuclear membrane 1 GCH1
external side of plasma membrane 1 GSR
cytoplasmic vesicle 2 GCH1, TF
nucleolus 1 REXO2
Early endosome 1 TF
clathrin-coated pit 1 TF
recycling endosome 1 TF
vesicle 1 TF
focal adhesion 2 CAT, REXO2
Peroxisome 2 CAT, DAO
Peroxisome matrix 2 CAT, DAO
peroxisomal matrix 2 CAT, DAO
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 REXO2
mitochondrial intermembrane space 1 REXO2
Late endosome 1 TF
cell projection 1 DAO
Secreted, extracellular space 1 DAO
Chromosome, telomere 1 ACD
chromosome, telomeric region 1 ACD
blood microparticle 1 TF
basal plasma membrane 1 TF
[Isoform 3]: Cytoplasm 1 REXO2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, TF
HFE-transferrin receptor complex 1 TF
endoplasmic reticulum lumen 1 TF
specific granule lumen 1 DAO
endocytic vesicle 1 TF
nuclear telomere cap complex 1 ACD
telomerase holoenzyme complex 1 ACD
clathrin-coated endocytic vesicle membrane 1 TF
vesicle coat 1 TF
catalase complex 1 CAT
neuron projection terminus 1 GCH1
shelterin complex 1 ACD
dense body 1 TF


文献列表

  • Pasquale Russo, Nicola De Simone, Vittorio Capozzi, Mari Luz Mohedano, José Ángel Ruiz-Masó, Gloria Del Solar, Paloma López, Giuseppe Spano. Selection of Riboflavin Overproducing Strains of Lactic Acid Bacteria and Riboflavin Direct Quantification by Fluorescence. Methods in molecular biology (Clifton, N.J.). 2021; 2280(?):3-14. doi: 10.1007/978-1-0716-1286-6_1. [PMID: 33751425]
  • Darío E Balcazar, María Cristina Vanrell, Patricia S Romano, Claudio A Pereira, Fernando A Goldbaum, Hernán R Bonomi, Carolina Carrillo. The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists. PLoS neglected tropical diseases. 2017 04; 11(4):e0005513. doi: 10.1371/journal.pntd.0005513. [PMID: 28406895]
  • Christian Vogl, Simon Grill, Oliver Schilling, Jörg Stülke, Matthias Mack, Jürgen Stolz. Characterization of riboflavin (vitamin B2) transport proteins from Bacillus subtilis and Corynebacterium glutamicum. Journal of bacteriology. 2007 Oct; 189(20):7367-75. doi: 10.1128/jb.00590-07. [PMID: 17693491]
  • A A Aver'yanov, V P Lapikova, O N Nikolaev, A I Stepanov. Active oxygen-associated control of rice blast disease by riboflavin and roseoflavin. Biochemistry. Biokhimiia. 2000 Nov; 65(11):1292-8. doi: . [PMID: 11112846]