Caffeine (BioDeep_00000229638)

Main id: BioDeep_00000397991

 

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


Caffeine

化学式: C8H10N4O2 (194.080372)
中文名称: 咖啡因
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(n(c(=O)n(c1=O)C)C)ncn2C
InChI: InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

描述信息

N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BC - Xanthine derivatives
D018377 - Neurotransmitter Agents > D058905 - Purinergic Agents > D058914 - Purinergic Antagonists
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
CONFIDENCE standard compound; EAWAG_UCHEM_ID 303
EAWAG_UCHEM_ID 303; CONFIDENCE standard compound
D - Dermatologicals
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

1 个代谢物同义名

Caffeine



数据库引用编号

32 个数据库交叉引用编号

分类词条

141 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ana M León-Inga, Sebastián Velásquez, Mónica Quintero, Nelson Taborda, Mónica P Cala. Effects of ultrafiltration membrane processing on the metabolic and sensory profiles of coffee extracts. Food chemistry. 2024 Sep; 451(?):139396. doi: 10.1016/j.foodchem.2024.139396. [PMID: 38670027]
  • Lin Chen, Jingyi Wang, Yijun Yang, Huajie Wang, Anan Xu, Junhui Ma, Yuefei Wang, Ping Xu. Identifying the temporal contributors and their interactions during dynamic formation of black tea cream. Food chemistry. 2024 Aug; 448(?):139138. doi: 10.1016/j.foodchem.2024.139138. [PMID: 38569407]
  • Lu Lu, Lu Wang, Ruyi Liu, Yingbin Zhang, Xinqiang Zheng, Jianliang Lu, Xinchao Wang, Jianhui Ye. An efficient artificial intelligence algorithm for predicting the sensory quality of green and black teas based on the key chemical indices. Food chemistry. 2024 May; 441(?):138341. doi: 10.1016/j.foodchem.2023.138341. [PMID: 38176147]
  • Riccardo Lorrai, Dario Cavaterra, Sara Giammaria, Diego Sbardella, Grazia Raffaella Tundo, Alessandra Boccaccini. Eye Diseases: When the Solution Comes from Plant Alkaloids. Planta medica. 2024 May; 90(6):426-439. doi: 10.1055/a-2283-2350. [PMID: 38452806]
  • Zihao Qiu, Jinmei Liao, Jiahao Chen, Ansheng Li, Minyao Lin, Hongmei Liu, Wei Huang, Binmei Sun, Jing Liu, Shaoqun Liu, Peng Zheng. Comprehensive analysis of fresh tea (Camellia sinensis cv. Lingtou Dancong) leaf quality under different nitrogen fertilization regimes. Food chemistry. 2024 May; 439(?):138127. doi: 10.1016/j.foodchem.2023.138127. [PMID: 38064834]
  • Nouran A I Tawfik, Zienab A El-Bakary, Khaleid F Abd El-Wakeil. Determination of caffeine in treated wastewater discharged in the Nile River with emphasis on the effect of zinc and physicochemical factors. Environmental science and pollution research international. 2024 Apr; 31(19):28124-28138. doi: 10.1007/s11356-024-32918-6. [PMID: 38530524]
  • Xuelian Dong, Qiang Chen, Wenyan Chi, Zhidong Qiu, Ye Qiu. A Metabolomics Study of the Effects of Eleutheroside B on Glucose and Lipid Metabolism in a Zebrafish Diabetes Model. Molecules (Basel, Switzerland). 2024 Mar; 29(7):. doi: 10.3390/molecules29071545. [PMID: 38611823]
  • Gina Mabrey, Majid S Koozehchian, Andrew T Newton, Alireza Naderi, Scott C Forbes, Monoem Haddad. The Effect of Creatine Nitrate and Caffeine Individually or Combined on Exercise Performance and Cognitive Function: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024 Mar; 16(6):. doi: 10.3390/nu16060766. [PMID: 38542677]
  • Luana L Souza, Egberto G Moura, Patricia C Lisboa. Can mothers consume caffeine? The issue of early life exposure and metabolic changes in offspring. Toxicology letters. 2024 Mar; 393(?):96-106. doi: 10.1016/j.toxlet.2024.02.005. [PMID: 38387763]
  • Sreelekshmi Sreekumar, Vinu Vijayan, Karyath Palliyath Gangaraj, Menakha Thangasornaraja, Manikantan Syamala Kiran. Caffeine-reinforced Collagen as Localized Microenvironmental Trans-Browning Bio-Matrix for Soft Tissue Repair and Regeneration in Bariatric Condition. Advanced biology. 2024 Mar; 8(3):e2300544. doi: 10.1002/adbi.202300544. [PMID: 38155149]
  • Qifang Jin, Zhong Wang, Devinder Sandhu, Lan Chen, Chenyu Shao, Siyi Xie, Fanghuizi Shang, Shuai Wen, Ting Wu, Huiying Jin, Feiyi Huang, Guizhi Liu, Jinyu Hu, Qin Su, Mengdi Huang, Qian Zhu, Biao Zhou, Lihua Zhu, Lvwen Peng, Zhonghua Liu, Jianan Huang, Na Tian, Shuoqian Liu. miR828a-CsMYB114 Module Negatively Regulates the Biosynthesis of Theobromine in Camellia sinensis. Journal of agricultural and food chemistry. 2024 Feb; 72(8):4464-4475. doi: 10.1021/acs.jafc.3c07736. [PMID: 38376143]
  • Érica Mendes Dos Santos, Lucas Malvezzi de Macedo, Janaína Artem Ataide, Jeany Delafiori, João Paulo de Oliveira Guarnieri, Paulo César Pires Rosa, Ana Lucia Tasca Gois Ruiz, Marcelo Lancellotti, Angela Faustino Jozala, Rodrigo Ramos Catharino, Gisele Anne Camargo, Ana Cláudia Paiva-Santos, Priscila Gava Mazzola. Antioxidant, antimicrobial and healing properties of an extract from coffee pulp for the development of a phytocosmetic. Scientific reports. 2024 02; 14(1):4453. doi: 10.1038/s41598-024-54797-0. [PMID: 38396007]
  • Tamyris de Aquino Gondim, Jhonyson Arruda Carvalho Guedes, Elenilson de Godoy Alves Filho, Gisele Silvestre da Silva, Natasha Veruska Dos Santos Nina, Firmino José do Nascimento Filho, André Luiz Atroch, Gilvan Ferreira Da Silva, Gisele Simone Lopes, Guilherme Julião Zocolo. Metabolomic approaches to explore chemodiversity in seeds of guaraná (Paullinia cupana) using UPLC-QTOF-MSE and NMR analysis. Analytical methods : advancing methods and applications. 2024 Feb; 16(8):1158-1174. doi: 10.1039/d3ay01737k. [PMID: 38189175]
  • Tania Russo, Francesca Coppola, Debora Paris, Lucia De Marchi, Valentina Meucci, Andrea Motta, Marianna Carbone, Anna Di Cosmo, Amadeu M V M Soares, Carlo Pretti, Ernesto Mollo, Rosa Freitas, Gianluca Polese. Exploring toxicological interactions in a changing sea: The case of the alkaloids caffeine and caulerpin. The Science of the total environment. 2024 Feb; 912(?):169190. doi: 10.1016/j.scitotenv.2023.169190. [PMID: 38092204]
  • Loukas Zagkos, Héléne T Cronjé, Benjamin Woolf, Roxane de La Harpe, Stephen Burgess, Christos S Mantzoros, Paul Elliott, Shuai Yuan, Susanna C Larsson, Ioanna Tzoulaki, Dipender Gill. Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization. BMC medicine. 2024 Feb; 22(1):81. doi: 10.1186/s12916-024-03298-y. [PMID: 38378567]
  • Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu. Bushen Tianjing Recipe inhibits human ovarian granulosa cell line KGN apoptosis induced by miR-23a through the regulation of the sirtuin family. Journal of ethnopharmacology. 2024 Jan; 319(Pt 3):117201. doi: 10.1016/j.jep.2023.117201. [PMID: 37739102]
  • Hong-Loan Tran, Kuei-Hung Lai, Hsun-Shuo Chang, Yi-Siao Chen, Hui-Chun Wang, Shuen-Shin Yang, Hsueh-Wei Chang, Chin-Mu Hsu, Chia-Hung Yen, Hui-Hua Hsiao. Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells. BMC complementary medicine and therapies. 2024 Jan; 24(1):28. doi: 10.1186/s12906-023-04325-w. [PMID: 38195460]
  • Meihui Chen, Ying Zhang, Yuhua Wang, Pengyuan Cheng, Qi Zhang, Mingzhe Li, Xiaoli Jia, Yibin Pan, Shaoxiong Lin, Zhengwei Luo, Haibin Wang, Jianghua Ye. Transcriptomic analysis of the effect of shaking and tumbling degree on quality formation of Wuyi rock tea. Journal of food science. 2024 Jan; 89(1):81-95. doi: 10.1111/1750-3841.16844. [PMID: 37983847]
  • Yan Yang, Juanjuan Chen, Huiyu Gao, Minglu Cui, Mingyu Zhu, Xuesong Xiang, Qi Wang. Characterization of the gut microbiota and fecal and blood metabolomes under various factors in urban children from Northwest China. Frontiers in cellular and infection microbiology. 2024; 14(?):1374544. doi: 10.3389/fcimb.2024.1374544. [PMID: 38585649]
  • Débora P DE Moraes, Daniele F Ferreira, Alexandre José Cichoski, Milene T Barcia, Juliano S Barin. Ultrasound combined with microwave hydrodiffusion and gravity for enhancement of caffeine extraction from guarana powder. Anais da Academia Brasileira de Ciencias. 2024; 96(2):e20230840. doi: 10.1590/0001-3765202420230840. [PMID: 38747838]
  • Rezvan Shaddel, Safoura Akbari-Alavijeh, Ilaria Cacciotti, Shima Yousefi, Merve Tomas, Esra Capanoglu, Ozgur Tarhan, Ali Rashidinejad, Atefe Rezaei, Mohammed Bhia, Seid Mahdi Jafari. Caffeine-loaded nano/micro-carriers: Techniques, bioavailability, and applications. Critical reviews in food science and nutrition. 2024; 64(15):4940-4965. doi: 10.1080/10408398.2022.2147143. [PMID: 36412258]
  • Firdous Sayeed Mohammed, Dinesh Babu, Zainab Irfan, Marwa A A Fayed. A review on the traditional uses, nutritive importance, pharmacognostic features, phytochemicals, and pharmacology of Momordica cymbalaria Hook F. PeerJ. 2024; 12(?):e16928. doi: 10.7717/peerj.16928. [PMID: 38436002]
  • Hua Zhang, Yakang Song, Zhenglei Fan, Jianyun Ruan, Jianhui Hu, Qunfeng Zhang. Aluminum Supplementation Mediates the Changes in Tea Plant Growth and Metabolism in Response to Calcium Stress. International journal of molecular sciences. 2023 Dec; 25(1):. doi: 10.3390/ijms25010530. [PMID: 38203700]
  • Naiyan Lu, Xue Mei, Xu Li, Xue Tang, Guofeng Yang, Wen Xiang. Preventive effects of caffeine on nicotine plus high-fat diet-induced hepatic steatosis and gain weight: a possible explanation for why obese smokers with high coffee consumption tend to be leaner. The British journal of nutrition. 2023 Dec; ?(?):1-10. doi: 10.1017/s0007114523002969. [PMID: 38149470]
  • Bailey R Meyer, Haley M White, Jared D McCormack, Emily D Niemeyer. Catechin Composition, Phenolic Content, and Antioxidant Properties of Commercially-Available Bagged, Gunpowder, and Matcha Green Teas. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Dec; 78(4):662-669. doi: 10.1007/s11130-023-01121-2. [PMID: 37923855]
  • Cong Zhang, Dingmei Zhang, Hegui Huang, Xiaoqian Lu, Huasong Shi, Kexin Liu, Xiaoling Guo, Rui Zhang, Hui Wang. Cathepsin D mediates prenatal caffeine exposure-caused NAFLD susceptibility in male rat offspring by regulating autophagy. Free radical biology & medicine. 2023 11; 208(?):684-699. doi: 10.1016/j.freeradbiomed.2023.09.026. [PMID: 37743032]
  • Graziela Taís Schmitt, Marcelo Oliveira Caetano, Vinícius Martins Marques, Amanda Gonçalves Kieling, Marie Launay, Lilia Itzel Acosta Muñiz, Luciana Paulo Gomes. Comparison of 17β-estradiol, bisphenol-A and caffeine concentration levels before and after the water treatment plant. Journal of water and health. 2023 Nov; 21(11):1716-1726. doi: 10.2166/wh.2023.234. [PMID: 38017601]
  • Xiang Cui, Wan Wei, Ziyi Zhang, Kun Liu, Ting Zhao, Jialin Zhang, Ani Zheng, Hanqing Xi, Xun He, Shuya Wang, Bing Zhu, Xinyan Gao. Caffeine impaired acupuncture analgesia in inflammatory pain by blocking adenosine A1 receptor. The journal of pain. 2023 Oct; ?(?):. doi: 10.1016/j.jpain.2023.10.025. [PMID: 37918469]
  • Zhiyi Xie, Ninghua Jiang, Minqiu Lin, Xinglishang He, Bo Li, Yingjie Dong, Suhong Chen, Guiyuan Lv. The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review. Molecules (Basel, Switzerland). 2023 Oct; 28(21):. doi: 10.3390/molecules28217355. [PMID: 37959774]
  • Shadia Hamoud Alshahrani, Yasir A Atia, Raheem Atiya Badir, Sami G Almalki, Nahla A Tayyib, Sana Shahab, Rosario Mireya Romero-Parra, Mohammed Kadhem Abid, Beneen M Hussien, Pushpamala Ramaiah. Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals. BMC endocrine disorders. 2023 Oct; 23(1):227. doi: 10.1186/s12902-023-01477-1. [PMID: 37864190]
  • Donné Minné, Juliet Stromin, Taskeen Docrat, Penelope Engel-Hills, Jeanine L Marnewick. The effects of tea polyphenols on emotional homeostasis: Understanding dementia risk through stress, mood, attention & sleep. Clinical nutrition ESPEN. 2023 10; 57(?):77-88. doi: 10.1016/j.clnesp.2023.06.008. [PMID: 37739736]
  • Gouhar Jahan Ashraf, Priya Das, Ranabir Sahu, Gouranga Nandi, Paramita Paul, Tarun Kumar Dua. Impact of ultrasound-assisted extraction of polyphenols and caffeine from green tea leaves using high-performance thin-layer chromatography. Biomedical chromatography : BMC. 2023 Oct; 37(10):e5698. doi: 10.1002/bmc.5698. [PMID: 37403293]
  • Greggory R Davis, Arnold G Nelson. Niacin supplementation impairs exercise performance. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2023 Oct; 93(5):385-391. doi: 10.1024/0300-9831/a000736. [PMID: 34696617]
  • Saeed Arshad, Mengli Wei, Qurban Ali, Ghulam Mustafa, Zhengqiang Ma, Yuanxin Yan. Paclitaxel and Caffeine-Taurine, New Colchicine Alternatives for Chromosomes Doubling in Maize Haploid Breeding. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914659. [PMID: 37834106]
  • Lidiia Samarina, Jaroslava Fedorina, Daria Kuzmina, Lyudmila Malyukova, Karina Manakhova, Tatyana Kovalenko, Alexandra Matskiv, Enhua Xia, Wei Tong, Zhaoliang Zhang, Alexey Ryndin, Yuriy L Orlov, Elena K Khlestkina. Analysis of Functional Single-Nucleotide Polymorphisms (SNPs) and Leaf Quality in Tea Collection under Nitrogen-Deficient Conditions. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914538. [PMID: 37833988]
  • Wenxiang Li, Guangyi Huang, Ningning Tang, Peng Lu, Li Jiang, Jian Lv, Yuanjun Qin, Yunru Lin, Fan Xu, Daizai Lei. Identification of dietary components in association with abdominal aortic calcification. Food & function. 2023 Sep; 14(18):8383-8395. doi: 10.1039/d3fo02920d. [PMID: 37609915]
  • Dino Davosir, Ivana Šola. Membrane permeabilizers enhance biofortification of Brassica microgreens by interspecific transfer of metabolites from tea (Camellia sinensis). Food chemistry. 2023 Sep; 420(?):136186. doi: 10.1016/j.foodchem.2023.136186. [PMID: 37087866]
  • Huan Han, Lijing Ke, Wei Xu, Huiqin Wang, Jianwu Zhou, Pingfan Rao. Incidental nanoparticles in black tea alleviate DSS-induced ulcerative colitis in BALB/c mice. Food & function. 2023 Aug; ?(?):. doi: 10.1039/d3fo00641g. [PMID: 37615587]
  • Burcu Uner, Melahat Sedanur Macit Celebi. Anti-obesity effects of chlorogenic acid and caffeine- lipid nanoparticles through PPAR-γ/C/EBP-ɑ pathways. International journal of obesity (2005). 2023 Aug; ?(?):. doi: 10.1038/s41366-023-01365-7. [PMID: 37596386]
  • Mengying Hong, Yushen Du, Dongdong Chen, Yuan Shi, Menglong Hu, Kejun Tang, Zhuping Hong, Xiangzhi Meng, Wan Xu, Gaoqi Wu, Yuanyuan Yao, Liubo Chen, Wenteng Chen, Chit Ying Lau, Li Sheng, Tian-Hao Zhang, Haigen Huang, Zheyu Fang, Yong Shen, Fangfang Sun, Jing Qian, Haibin Qu, Shu Zheng, Suzhan Zhang, Kefeng Ding, Ren Sun. Martynoside rescues 5-fluorouracil-impaired ribosome biogenesis by stabilizing RPL27A. Science bulletin. 2023 08; 68(15):1662-1677. doi: 10.1016/j.scib.2023.07.018. [PMID: 37481436]
  • Jiahui Yin, Yu Ding, Feikang Xu, Leiyong Zhao, Rongpeng Gong, Jiguo Yang, Yuanxiang Liu. Does the timing of intake matter? Association between caffeine intake and depression: Evidence from the National Health and Nutrition Examination Survey. Journal of affective disorders. 2023 Aug; ?(?):. doi: 10.1016/j.jad.2023.07.115. [PMID: 37543113]
  • Roberto Tira, Giovanna Viola, Carlo Giorgio Barracchia, Francesca Parolini, Francesca Munari, Stefano Capaldi, Michael Assfalg, Mariapina D'Onofrio. Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer's Associated Tau Protein. Journal of agricultural and food chemistry. 2023 Aug; 71(30):11429-11441. doi: 10.1021/acs.jafc.3c01072. [PMID: 37466260]
  • Vinicius Diniz, Susanne Rath. Adsorption of aqueous phase contaminants of emerging concern by activated carbon: Comparative fixed-bed column study and in situ regeneration methods. Journal of hazardous materials. 2023 Jul; 459(?):132197. doi: 10.1016/j.jhazmat.2023.132197. [PMID: 37543021]
  • Tom Gurney, Naomi Bradley, Dionisio Izquierdo, Flaminia Ronca. Cognitive effects of guarana supplementation with maximal intensity cycling. The British journal of nutrition. 2023 Jul; 130(2):253-260. doi: 10.1017/s0007114522002859. [PMID: 36146946]
  • Ahmed Alaa Kassem, Marwa Hasanein Asfour, Sameh Hosam Abd El-Alim, Mohamed Abdelrazik Khattab, Abeer Salama. Topical caffeine-loaded nanostructured lipid carriers for enhanced treatment of cellulite: A 32 full factorial design optimization and in vivo evaluation in rats. International journal of pharmaceutics. 2023 Jul; 643(?):123271. doi: 10.1016/j.ijpharm.2023.123271. [PMID: 37499772]
  • David Fernando Dos Santos, Vandressa Alves, Edlaine Costa, André Martins, Alexia Flavia França Vieira, Gustavo Henrique Fidelis Dos Santos, Cátia Tavares Dos Passos Francisco, Vânia Zanella Pinto. Yerba Mate (Ilex paraguariensis) Processing and Extraction: Retention of Bioactive Compounds. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Jul; ?(?):. doi: 10.1007/s11130-023-01082-6. [PMID: 37466823]
  • Sirine Atwi-Ghaddar, Lydie Zerwette, Emilie Destandau, Eric Lesellier. Supercritical Fluid Extraction (SFE) of Polar Compounds from Camellia sinensis Leaves: Use of Ethanol/Water as a Green Polarity Modifier. Molecules (Basel, Switzerland). 2023 Jul; 28(14):. doi: 10.3390/molecules28145485. [PMID: 37513357]
  • Haley A Abernathy, Ross M Boyce, Michael H Reiskind. Exploring the effects of caffeine on Aedes albopictus (Diptera: Culicidae) survival and fecundity. Journal of medical entomology. 2023 07; 60(4):837-841. doi: 10.1093/jme/tjad047. [PMID: 37085153]
  • Haysem M Alhassen, Fiona J Dyer, Ross M Thompson. The photolytic breakdown of caffeine and paracetamol residues in surface water. Water environment research : a research publication of the Water Environment Federation. 2023 Jul; ?(?):e10909. doi: 10.1002/wer.10909. [PMID: 37429828]
  • Johanna C Arroyave-Ospina, Manon Buist-Homan, Martina Schmidt, Han Moshage. Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jul; 165(?):114884. doi: 10.1016/j.biopha.2023.114884. [PMID: 37423170]
  • Lu Zhang, Jiahui Yin, Jinling Li, Haiyang Sun, Yuanxiang Liu, Jiguo Yang. Association between dietary caffeine intake and severe headache or migraine in US adults. Scientific reports. 2023 Jun; 13(1):10220. doi: 10.1038/s41598-023-36325-8. [PMID: 37353507]
  • Idalia Casas-Hinojosa, Leobardo Manuel Gómez-Oliván, Veronica Margarita Gutierrez-Noya, Sandra Gracía-Medina, Karina Elisa Rosales-Pérez, José Manuel Orozco-Hernández, Gustavo Axel Elizalde-Velázquez, Marcela Galar-Martínez, Octavio Dublán-García, María Dolores Hernández-Navarro, Hariz Islas-Flores. Integrative approach to elucidate the embryological effects of caffeine in Cyprinus carpio: Bioconcentration and alteration of oxidative stress-related gene expression patterns. The Science of the total environment. 2023 Jun; 894(?):165016. doi: 10.1016/j.scitotenv.2023.165016. [PMID: 37348709]
  • Erick V S Motta, Ryan L W Arnott, Nancy A Moran. Caffeine Consumption Helps Honey Bees Fight a Bacterial Pathogen. Microbiology spectrum. 2023 06; 11(3):e0052023. doi: 10.1128/spectrum.00520-23. [PMID: 37212661]
  • Sumit Bansal, C Austin Zamarripa, Tory R Spindle, Elise M Weerts, Kenneth E Thummel, Ryan Vandrey, Mary F Paine, Jashvant D Unadkat. Evaluation of Cytochrome P450-Mediated Cannabinoid-Drug Interactions in Healthy Adult Participants. Clinical pharmacology and therapeutics. 2023 Jun; ?(?):. doi: 10.1002/cpt.2973. [PMID: 37313955]
  • Lukas Babylon, Julia Meißner, Gunter P Eckert. Combination of Secondary Plant Metabolites and Micronutrients Improves Mitochondrial Function in a Cell Model of Early Alzheimer's Disease. International journal of molecular sciences. 2023 Jun; 24(12):. doi: 10.3390/ijms241210029. [PMID: 37373177]
  • Javier Gallardo-Ignacio, Anislada Santibáñez, Octavio Oropeza-Mariano, Ricardo Salazar, Rosa Mariana Montiel-Ruiz, Sandra Cabrera-Hilerio, Manasés Gonzáles-Cortazar, Francisco Cruz-Sosa, Pilar Nicasio-Torres. Chemical and Biological Characterization of Green and Processed Coffee Beans from Coffea arabica Varieties. Molecules (Basel, Switzerland). 2023 Jun; 28(12):. doi: 10.3390/molecules28124685. [PMID: 37375240]
  • Marco Carnevale Miino, Tomáš Macsek, Taťána Halešová, Tomáš Chorazy, Petr Hlavínek. Pharmaceutical and narcotics monitoring in Brno wastewater system and estimation of seasonal effect on the abuse of illicit drugs by a wastewater-based epidemiology approach. The Science of the total environment. 2023 May; ?(?):164386. doi: 10.1016/j.scitotenv.2023.164386. [PMID: 37263433]
  • Elisa Bernklau, H S Arathi. Seasonal patterns of beneficial phytochemical availability in honey and stored pollen from honey bee colonies in large apiaries. Journal of economic entomology. 2023 May; ?(?):. doi: 10.1093/jee/toad096. [PMID: 37247384]
  • Philippa A Jackson, Charlotte Kenney, Joanne Forster, Ellen F Smith, Rian Elcoate, Bethany Spittlehouse, Jodee Johnson, David O Kennedy. Acute Cognitive Performance and Mood Effects of Coffeeberry Extract: A Randomized, Double Blind, Placebo-Controlled Crossover Study in Healthy Humans. Nutrients. 2023 May; 15(11):. doi: 10.3390/nu15112418. [PMID: 37299382]
  • F Impellitteri, K Yunko, V Martyniuk, T Matskiv, S Lechachenko, V Khoma, A Mudra, G Piccione, O Stoliar, C Faggio. Physiological and biochemical responses to caffeine and microplastics in Mytilus galloprovincialis. The Science of the total environment. 2023 May; ?(?):164075. doi: 10.1016/j.scitotenv.2023.164075. [PMID: 37230349]
  • Maria de Fátima C Santos, Katlin S Rech, Lívia M Dutra, Leociley R A Menezes, Alan D da C Santos, Noemi Nagata, Maria Élida A Stefanello, Andersson Barison. 1H HR-MAS NMR chemical profile and chemometric analysis as a tool for quality control of different cultivars of green tea (Camellia sinensis). Food chemistry. 2023 May; 408(?):135016. doi: 10.1016/j.foodchem.2022.135016. [PMID: 36525726]
  • Miroslav Gancar, Elena Kurin, Zuzana Bednarikova, Jozef Marek, Pavel Mucaji, Milan Nagy, Zuzana Gazova. Green tea leaf constituents inhibit the formation of lysozyme amyloid aggregates: An effect of mutual interactions. International journal of biological macromolecules. 2023 May; 242(Pt 2):124856. doi: 10.1016/j.ijbiomac.2023.124856. [PMID: 37178892]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Yejin Ahn, Hee Hwan Lee, Byung-Hak Kim, Sang Jae Park, Young Suk Kim, Hyung Joo Suh, Kyungae Jo. Heukharang lettuce (Lactuca sativa L.) leaf extract displays sleep-promoting effects through GABAA receptor. Journal of ethnopharmacology. 2023 May; ?(?):116602. doi: 10.1016/j.jep.2023.116602. [PMID: 37149068]
  • Ruihong Dong, Mengting Zhu, You Long, Qiang Yu, Chang Li, Jianhua Xie, Yousheng Huang, Yi Chen. Exploring correlations between green coffee bean components and thermal contaminants in roasted coffee beans. Food research international (Ottawa, Ont.). 2023 05; 167(?):112700. doi: 10.1016/j.foodres.2023.112700. [PMID: 37087268]
  • Oliver J Perkin, Yung-Chih Chen, Drusus A Johnson, Joel E Thomas, Greg Atkinson, James A Betts, Javier T Gonzalez. Postprandial metabolic responses to high-fat feeding in healthy adults following ingestion of oolong tea-derived polymerized polyphenols: a randomized, double-blinded, placebo-controlled crossover study. The American journal of clinical nutrition. 2023 Apr; ?(?):. doi: 10.1016/j.ajcnut.2023.04.020. [PMID: 37080462]
  • Xiaozeng Mi, Chun Yang, Dahe Qiao, Mengsha Tang, Yan Guo, Sihui Liang, Yan Li, Zhengwu Chen, Juan Chen. De novo full length transcriptome analysis of a naturally caffeine-free tea plant reveals specificity in secondary metabolic regulation. Scientific reports. 2023 04; 13(1):6015. doi: 10.1038/s41598-023-32435-5. [PMID: 37045909]
  • Yan Cheng, Fumin Xue, Yu Yang. Hot Water Extraction of Antioxidants from Tea Leaves-Optimization of Brewing Conditions for Preparing Antioxidant-Rich Tea Drinks. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28073030. [PMID: 37049793]
  • Minghui Hu, Muxuan Han, Hao Zhang, Zifa Li, Kaiyong Xu, Huaixing Kang, Jiancheng Zong, Feng Zhao, Yuanxiang Liu, Wei Liu. Curcumin (CUMINUP60®) mitigates exercise fatigue through regulating PI3K/Akt/AMPK/mTOR pathway in mice. Aging. 2023 Mar; 15(6):2308-2320. doi: 10.18632/aging.204614. [PMID: 36988546]
  • Liang Zhang, Yongquan Xu, Zhonghua Liu. Tea: From Historical Documents to Modern Technology. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28072992. [PMID: 37049755]
  • Jing-Jing Zhang, Qi-Jie Xu, Claudia Schmidt, Mohamed A Abu El Maaty, Jinglin Song, Chunqiu Yu, Jun Zhou, Kang Han, Hao Sun, Angela Casini, Ingo Ott, Stefan Wölfl. Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo. Journal of medicinal chemistry. 2023 03; 66(6):3995-4008. doi: 10.1021/acs.jmedchem.2c01925. [PMID: 36898000]
  • Heider Carreño, Elena E Stashenko, Patricia Escobar. Essential Oils Distilled from Colombian Aromatic Plants and Their Constituents as Penetration Enhancers for Transdermal Drug Delivery. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062872. [PMID: 36985843]
  • Thirakorn Mokkawes, Samuel P de Visser. Caffeine biodegradation by cytochrome P450 1A2. What determines the product distributions?. Chemistry (Weinheim an der Bergstrasse, Germany). 2023 Mar; ?(?):e202203875. doi: 10.1002/chem.202203875. [PMID: 36929809]
  • Gaber El-Saber Batiha, Ali Esmail Al-Snafi, Mahdi M Thuwaini, John Oluwafemi Teibo, Hazem M Shaheen, Ayomide Peter Akomolafe, Titilade Kehinde Ayandeyi Teibo, Hayder M Al-Kuraishy, Ali I Al-Garbeeb, Athanasios Alexiou, Marios Papadakis. Morus alba: a comprehensive phytochemical and pharmacological review. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Mar; ?(?):. doi: 10.1007/s00210-023-02434-4. [PMID: 36877269]
  • Jessica Virgili, Petros Motitis, Gabrielle Julal, Yiannis Mavrommatis, Leta Pilic. The impact of genetic variability on the relationship between caffeine and cardiometabolic outcomes: A systematic review. Nutrition bulletin. 2023 Mar; 48(1):28-42. doi: 10.1111/nbu.12606. [PMID: 36842137]
  • Scott A Conger, Lara M Tuthill, Mindy L Millard-Stafford. Does Caffeine Increase Fat Metabolism? A Systematic Review and Meta-Analysis. International journal of sport nutrition and exercise metabolism. 2023 Mar; 33(2):112-120. doi: 10.1123/ijsnem.2022-0131. [PMID: 36495873]
  • Nuria Alcubierre, Minerva Granado-Casas, Patricia Bogdanov, Cristina Hernández, Hugo Ramos, Esmeralda Castelblanco, Jordi Real, Esther Rubinat-Arnaldo, Alicia Traveset, Marta Hernández, Carmen Jurjo, Jesús Vioque, Eva Maria Navarrete-Muñoz, Rafael Simó, Didac Mauricio. Caffeine and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus: Findings from Clinical and Experimental Studies. Nutrients. 2023 Feb; 15(5):. doi: 10.3390/nu15051169. [PMID: 36904168]
  • Duhyeon Kim, Seonghui Kim, Minseok Yoon, Min Young Um, Suengmok Cho. Effects of Chronic Administration of Green Tea Ethanol Extract on Sleep Architecture in Mice: A Comparative Study with a Representative Stimulant Caffeine. Nutrients. 2023 Feb; 15(4):. doi: 10.3390/nu15041042. [PMID: 36839400]
  • Yue Xu, Li Ma, Fei Liu, Lei Yao, Wencui Wang, Suzhen Yang, Tingting Han. Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115868. doi: 10.1016/j.jep.2022.115868. [PMID: 36309115]
  • Zhimin Wu, Wenxin Yu, Weiju Ni, Cuiqin Teng, Weile Ye, Cuiping Yu, Yu Zeng. Improvement of obesity by Liupao tea is through the IRS-1/PI3K/AKT/GLUT4 signaling pathway according to network pharmacology and experimental verification. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Feb; 110(?):154633. doi: 10.1016/j.phymed.2022.154633. [PMID: 36628832]
  • Arleta Sierakowska, Beata Jasiewicz, Łukasz Piosik, Lucyna Mrówczyńska. New C8-substituted caffeine derivatives as promising antioxidants and cytoprotective agents in human erythrocytes. Scientific reports. 2023 01; 13(1):1785. doi: 10.1038/s41598-022-27205-8. [PMID: 36720903]
  • Chang Liu, Haotian Zhao, Yi Yan, Weijun Yang, Songyue Chen, Ge Song, Xuehan Li, Yujia Gu, Hezhang Yun, Yi Li. Synergistic Effect of Rhodiola rosea and Caffeine Supplementation on the Improvement of Muscle Strength and Muscular Endurance: A Pilot Study for Rats, Resistance Exercise-Untrained and -Trained Volunteers. Nutrients. 2023 Jan; 15(3):. doi: 10.3390/nu15030582. [PMID: 36771289]
  • Brian Hack, Eduardo Macedo Penna, Tyler Talik, Rohan Chandrashekhar, Mindy Millard-Stafford. Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis. Nutrients. 2023 Jan; 15(2):. doi: 10.3390/nu15020434. [PMID: 36678305]
  • Javier Palacios, Adrián Paredes, Fredi Cifuentes, Marcelo A Catalán, Angel Luis García-Villalón, Jorge Borquez, Mario J Simirgiotis, Matthew Jones, Amy Foster, David J Greensmith. A hydroalcoholic extract of Senecio nutans SCh. Bip (Asteraceae); its effects on cardiac function and chemical characterization. Journal of ethnopharmacology. 2023 Jan; 300(?):115747. doi: 10.1016/j.jep.2022.115747. [PMID: 36152785]
  • Hangxiu Che, Yaqun Wang, Jinhui Lao, Yixin Deng, Chirui Xu, Hanxiao Yin, Zheng Tang, Yonghong Huang, Hong Xu. Role of purinergic signalling in obesity-associated end-organ damage: focus on the effects of natural plant extracts. Frontiers in endocrinology. 2023; 14(?):1181948. doi: 10.3389/fendo.2023.1181948. [PMID: 37476493]
  • Géssica Aline Nogueira Dos Santos, Celso Scherer Filho, Flávia Camila Schimpl, Sarah Caroline Ribeiro de Souza, Adamir da Rocha Nina Junior, Rebeca Patrícia Omena Garcia, José Ferreira da Silva. Metabolism of guarana (Paullinia cupana Kunth var. sorbilis) plants and fruit production subjected to glyphosate doses. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2023; 58(1):69-79. doi: 10.1080/03601234.2023.2172275. [PMID: 36747348]
  • Hao Zuo, Xiongyuan Si, Ping Li, Juan Li, Zhihui Chen, Penghui Li, Changsong Chen, Zhonghua Liu, Jian Zhao. Dynamic change of tea (Camellia sinensis) leaf cuticular wax in white tea processing for contribution to tea flavor formation. Food research international (Ottawa, Ont.). 2023 01; 163(?):112182. doi: 10.1016/j.foodres.2022.112182. [PMID: 36596123]
  • Shiqi Zhao, Haiyan Cheng, Ping Xu, Yuefei Wang. Regulation of biosynthesis of the main flavor-contributing metabolites in tea plant (Camellia sinensis): A review. Critical reviews in food science and nutrition. 2023; 63(30):10520-10535. doi: 10.1080/10408398.2022.2078787. [PMID: 35608014]
  • Matthew A Pronschinske, Steven R Corsi, Celeste Hockings. Evaluating pharmaceuticals and other organic contaminants in the Lac du Flambeau Chain of Lakes using risk-based screening techniques. PloS one. 2023; 18(6):e0286571. doi: 10.1371/journal.pone.0286571. [PMID: 37267346]
  • Majid Bagheri, Xiaolong He, Mariam K Al-Lami, Nadege Oustriere, Wenyan Liu, Matt A Limmer, Honglan Shi, Joel G Burken. Assessing plant uptake of organic contaminants by food crops tomato, wheat, and corn through sap concentration factor. International journal of phytoremediation. 2023; 25(9):1215-1224. doi: 10.1080/15226514.2022.2144797. [PMID: 36356305]
  • Preeti Dali, Pravin Shende. Self-Assembled Lipid Polymer Hybrid Nanoparticles Using Combinational Drugs for Migraine Via Intranasal Route. AAPS PharmSciTech. 2022 Dec; 24(1):20. doi: 10.1208/s12249-022-02479-3. [PMID: 36526821]
  • Vita Paramita, Nanang Masruchin, Yohanes Widodo Wirohadidjojo, Buwono Puruhito, Hermawan Dwi Ariyanto, Mohamad Endy Yulianto, Indah Hartati, Eflita Yohana, Furqon Hidayatulloh, Tris Sutrisno, Bagus Wijayanto. Multiple response optimizations on the leached-spray-dried bancha green tea towards healthy ageing. Scientific reports. 2022 12; 12(1):21347. doi: 10.1038/s41598-022-25644-x. [PMID: 36494428]
  • Fei Ye, Xinbo Guo, Bo Li, Haiqiang Chen, Xiaoyan Qiao. Characterization of Effects of Different Tea Harvesting Seasons on Quality Components, Color and Sensory Quality of 'Yinghong 9' and 'Huangyu' Large-Leaf-Variety Black Tea. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248720. [PMID: 36557856]
  • Mai M Anwar, Ibrahim M Ibrahim Laila. Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats. BMC complementary medicine and therapies. 2022 Dec; 22(1):327. doi: 10.1186/s12906-022-03802-y. [PMID: 36482339]
  • Francesca Paola Luongo, Sofia Passaponti, Alesandro Haxhiu, Maryam Raeispour, Giuseppe Belmonte, Laura Governini, Livio Casarini, Paola Piomboni, Alice Luddi. Bitter Taste Receptors and Endocrine Disruptors: Cellular and Molecular Insights from an In Vitro Model of Human Granulosa Cells. International journal of molecular sciences. 2022 Dec; 23(24):. doi: 10.3390/ijms232415540. [PMID: 36555195]
  • David O Kennedy, Emma L Wightman. Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients. Sports medicine (Auckland, N.Z.). 2022 Dec; 52(Suppl 1):69-90. doi: 10.1007/s40279-022-01796-8. [PMID: 36447122]
  • Hui-Lin Yang, Ying Li, Yi Chen, Si-Ying Chen, Yue-Ting Li, Yong Huang, Lin Zheng, Jing Huang, Yong-Lin Wang, Zi-Peng Gong. [Effect of Laportea bulbifera extract on CYP450 enzyme activities in rats by Cocktail probe drug method]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Dec; 47(23):6320-6332. doi: 10.19540/j.cnki.cjcmm.20220623.204. [PMID: 36604876]
  • Juan Cruz Carrizo, Sung Vo Duy, Gabriel Munoz, Guido Marconi, María Valeria Amé, Sébastien Sauvé. Suspect screening of pharmaceuticals, illicit drugs, pesticides, and other emerging contaminants in Argentinean Piaractus mesopotamicus, a fish species used for local consumption and export. Chemosphere. 2022 Dec; 309(Pt 1):136769. doi: 10.1016/j.chemosphere.2022.136769. [PMID: 36209849]
  • Misato Ota, Yasuhito Maki, Ling-Yu Xu, Toshiaki Makino. Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers. Journal of ethnopharmacology. 2022 Nov; 298(?):115625. doi: 10.1016/j.jep.2022.115625. [PMID: 35970315]