bendiocarb (BioDeep_00000002231)

   

human metabolite blood metabolite


代谢物信息卡片


2,2-dimethyl-2H-1,3-benzodioxol-4-yl N-methylcarbamate

化学式: C11H13NO4 (223.0845)
中文名称: 恶虫威
谱图信息: 最多检出来源 Rattus norvegicus(blood) 33.13%

分子结构信息

SMILES: CC1(C)Oc2cccc(c2O1)OC(=O)NC
InChI: InChI=1S/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13)

描述信息

C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
CONFIDENCE standard compound; INTERNAL_ID 8476
CONFIDENCE standard compound; INTERNAL_ID 4024
CONFIDENCE standard compound; INTERNAL_ID 2606
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

11 个代谢物同义名

2,2-dimethyl-2H-1,3-benzodioxol-4-yl N-methylcarbamate; 2,2-Dimethyl-1,3-benzodioxol-4-ol methylcarbamic acid; 2,2-Dimethyl-4-(methylcarbamoyloxy)-1,3-benzodioxole; 2,2-Dimethyl-1,3-benzodioxol-4-ol methylcarbamate; 2,3-Isopropylidenedioxyphenyl methylcarbamic acid; 2,3-Isopropylidenedioxyphenyl methylcarbamate; bendiocarb; FICAM 80W; FICAM W; FICAM; Bendiocarb



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ABCB4, CASP3, CASP9, HPGDS, MME, RP1
Peripheral membrane protein 2 ACHE, CYP1B1
Endoplasmic reticulum membrane 4 CD4, CYP1B1, HSP90B1, PON1
Nucleus 7 ACHE, CASP3, CASP9, CHD7, HSP90B1, KDR, RP1
cytosol 5 ABCB4, CASP3, CASP9, HPGDS, HSP90B1
dendrite 1 MME
trans-Golgi network 1 MME
nucleoplasm 5 ABCB4, CASP3, CHD7, HPGDS, SCNN1G
Cell membrane 5 ABCB4, ACHE, CD4, KDR, MME
Multi-pass membrane protein 2 ABCB4, SCNN1G
Synapse 2 ACHE, MME
cell junction 1 KDR
cell surface 3 ACHE, APOH, MME
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ACHE, ATRN, KDR
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, MME
smooth endoplasmic reticulum 1 HSP90B1
synaptic vesicle 1 MME
Presynapse 1 MME
endosome 1 KDR
plasma membrane 9 ABCB4, ACHE, ATRN, BCHE, CD4, CSF2, KDR, MME, SCNN1G
Membrane 5 ABCB4, ACHE, CYP1B1, HSP90B1, MME
apical plasma membrane 2 ABCB4, SCNN1G
axon 1 MME
brush border 1 MME
extracellular exosome 8 ABCB4, APOH, ATRN, HSP90B1, MME, PON1, SCNN1G, SOD2
endoplasmic reticulum 2 HSP90B1, KDR
extracellular space 6 ACHE, APOH, ATRN, BCHE, CSF2, PON1
perinuclear region of cytoplasm 2 ACHE, HSP90B1
intercellular canaliculus 1 ABCB4
mitochondrion 3 CASP9, CYP1B1, SOD2
protein-containing complex 2 CASP9, HSP90B1
intracellular membrane-bounded organelle 3 CSF2, CYP1B1, HPGDS
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 ATRN, CD4
Secreted 4 ACHE, APOH, BCHE, CSF2
extracellular region 7 ACHE, APOH, BCHE, CSF2, HSP90B1, KDR, PON1
[Isoform 2]: Secreted 2 ATRN, KDR
Mitochondrion matrix 1 SOD2
mitochondrial matrix 1 SOD2
Extracellular side 1 ACHE
anchoring junction 1 KDR
photoreceptor connecting cilium 1 RP1
photoreceptor inner segment 1 RP1
photoreceptor outer segment 1 RP1
external side of plasma membrane 3 CD4, KDR, SCNN1G
chylomicron 1 APOH
high-density lipoprotein particle 2 APOH, PON1
very-low-density lipoprotein particle 1 APOH
cytoplasmic vesicle 1 MME
microtubule cytoskeleton 1 RP1
nucleolus 1 CHD7
midbody 1 HSP90B1
Early endosome 3 CD4, KDR, MME
spindle midzone 1 RP1
Single-pass type II membrane protein 1 MME
Apical cell membrane 2 ABCB4, SCNN1G
Membrane raft 4 ABCB4, CD4, KDR, MME
Cytoplasm, cytoskeleton 1 RP1
focal adhesion 4 ABCB4, HSP90B1, MME, RP1
microtubule 1 RP1
mitochondrial nucleoid 1 SOD2
basement membrane 1 ACHE
collagen-containing extracellular matrix 2 APOH, HSP90B1
axoneme 1 RP1
ciliary tip 1 RP1
nuclear speck 1 RP1
receptor complex 1 KDR
chromatin 1 CHD7
microtubule associated complex 1 RP1
[Isoform 3]: Nucleus 1 RP1
Cell projection, cilium, photoreceptor outer segment 1 RP1
blood microparticle 2 BCHE, PON1
Cytoplasm, cytoskeleton, cilium axoneme 1 RP1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 3]: Secreted 1 ATRN
sorting endosome 1 KDR
microtubule organizing center 1 RP1
sodium channel complex 1 SCNN1G
Melanosome 1 HSP90B1
side of membrane 1 ACHE
sperm plasma membrane 1 HSP90B1
clathrin-coated vesicle 1 ABCB4
secretory granule membrane 1 MME
endoplasmic reticulum lumen 3 BCHE, CD4, HSP90B1
Cytoplasmic vesicle, clathrin-coated vesicle 1 ABCB4
microtubule plus-end 1 RP1
nuclear envelope lumen 1 BCHE
apoptosome 1 CASP9
clathrin-coated endocytic vesicle membrane 1 CD4
Sarcoplasmic reticulum lumen 1 HSP90B1
[Isoform 1]: Nucleus 2 CHD7, RP1
cytoplasmic microtubule 1 RP1
synaptic cleft 1 ACHE
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 ATRN
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
spherical high-density lipoprotein particle 1 PON1
endocytic vesicle lumen 1 HSP90B1
T cell receptor complex 1 CD4
platelet dense granule lumen 1 APOH
endoplasmic reticulum chaperone complex 1 HSP90B1
neuron projection terminus 1 MME
[Isoform H]: Cell membrane 1 ACHE
caspase complex 1 CASP9
[Isoform 3]: Nucleus, nucleolus 1 CHD7


文献列表

  • Hend H A Salem, Shaimaa H Mohammed, Randa I Eltaly, Moataz A M Moustafa, Adrien Fónagy, Shaimaa M Farag. Co-application of entomopathogenic fungi with chemical insecticides against Culex pipiens. Journal of invertebrate pathology. 2023 Mar; 198(?):107916. doi: 10.1016/j.jip.2023.107916. [PMID: 37004917]
  • Milena Jankowska, Bartosz Augustyn, Justyna Maliszewska, Barbara Przeździecka, Dawid Kubiak, Olga Chełchowska, Jagoda Kaczorek, Dominik Knop, Kornelia Krajnik, Hanna Kletkiewicz, Jacek Kęsy, Justyna Rogalska, Maria Stankiewicz. Sublethal biochemical, behavioral, and physiological toxicity of extremely low dose of bendiocarb insecticide in Periplaneta americana (Blattodea: Blattidae). Environmental science and pollution research international. 2023 Feb; ?(?):. doi: 10.1007/s11356-023-25602-8. [PMID: 36745351]
  • Mary Prahl, Pamela Odorizzi, David Gingrich, Mary Muhindo, Tara McIntyre, Rachel Budker, Prasanna Jagannathan, Lila Farrington, Mayimuna Nalubega, Felistas Nankya, Esther Sikyomu, Kenneth Musinguzi, Kate Naluwu, Ann Auma, Abel Kakuru, Moses R Kamya, Grant Dorsey, Francesca Aweeka, Margaret E Feeney. Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy. Nature communications. 2021 01; 12(1):132. doi: 10.1038/s41467-020-20475-8. [PMID: 33420104]
  • Caglar Adiguzel, Yusuf Kalender. Bendiocarb-induced nephrotoxicity in rats and the protective role of vitamins C and E. Environmental science and pollution research international. 2020 Feb; 27(6):6449-6458. doi: 10.1007/s11356-019-07260-x. [PMID: 31873894]
  • Milena Jankowska, Justyna Wiśniewska, Łukasz Fałtynowicz, Bruno Lapied, Maria Stankiewicz. Menthol Increases Bendiocarb Efficacy Through Activation of Octopamine Receptors and Protein Kinase A. Molecules (Basel, Switzerland). 2019 Oct; 24(20):. doi: 10.3390/molecules24203775. [PMID: 31635151]
  • Fatma Gökçe Apaydin, Hatice Baş, Suna Kalender, Yusuf Kalender. Bendiocarb induced histopathological and biochemical alterations in rat liver and preventive role of vitamins C and E. Environmental toxicology and pharmacology. 2017 Jan; 49(?):148-155. doi: 10.1016/j.etap.2016.11.018. [PMID: 28013143]
  • A K Murchie, S Clawson, I Rea, I W N Forsythe, A W Gordon, S Jess. DEET (N,N-diethyl-meta-toluamide)/PMD (para-menthane-3,8-diol) repellent-treated mesh increases Culicoides catches in light traps. Parasitology research. 2016 Sep; 115(9):3543-9. doi: 10.1007/s00436-016-5119-x. [PMID: 27179956]
  • Yemane Yeebiyo, Dereje Dengela, Alemayehu Getachew Tesfaye, Gedeon Yohannes Anshebo, Lena Kolyada, Robert Wirtz, Sheleme Chibsa, Christen Fornadel, Kristen George, Allison Belemvire, Hiwot Solomon Taffese, Bradford Lucas. Short persistence of bendiocarb sprayed on pervious walls and its implication for the indoor residual spray program in Ethiopia. Parasites & vectors. 2016 May; 9(?):266. doi: 10.1186/s13071-016-1549-7. [PMID: 27151229]
  • Eva Petrovova, Halina Purzyc, David Mazensky, Lenka Luptakova, Norbert Torma, Igor Sopoliga, David Sedmera. Morphometric alterations, steatosis, fibrosis and active caspase-3 detection in carbamate bendiocarb treated rabbit liver. Environmental toxicology. 2015 Feb; 30(2):212-22. doi: 10.1002/tox.21887. [PMID: 23836410]
  • Katarina Holovska, Viera Almasiova, Viera Cigankova. Ultrastructural changes in the rabbit liver induced by carbamate insecticide bendiocarb. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2014; 49(8):616-23. doi: 10.1080/03601234.2014.911593. [PMID: 24901965]
  • Jana Polláková, Natália Kovalkovičová, Tomáš Csank, Juraj Pistl, Alica Kočišová, Jaroslav Legáth. Evaluation of bendiocarb cytotoxicity in mammalian and insect cell cultures. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012; 47(6):538-43. doi: 10.1080/03601234.2012.665671. [PMID: 22494377]
  • Mayumi Allinson, Shiho Kageyama, Daisuke Nakajima, Ryo Kamata, Fujio Shiraishi, Sumio Goto, Scott Andrew Salzman, Graeme Allinson. A pilot survey of 39 Victorian WWTP effluents using a high speed luminescent umu test in conjunction with a novel GC-MS-database technique for automatic identification of micropollutants. Water science and technology : a journal of the International Association on Water Pollution Research. 2012; 66(4):768-74. doi: 10.2166/wst.2012.242. [PMID: 22766865]
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