2,4-Toluenediamine (BioDeep_00000002220)
human metabolite
代谢物信息卡片
2,4-Diaminotoluene, monohydrochloride
化学式: C7H10N2 (122.0844)
中文名称: 2,4-二氨基甲苯
谱图信息:
最多检出来源 Mus musculus(plant) 3.09%
分子结构信息
SMILES: CC1=C(C=C(C=C1)N)N
InChI: InChI=1S/C7H10N2/c1-5-2-3-6(8)4-7(5)9/h2-4H,8-9H2,1H3
描述信息
2,4-toluenediamine belongs to the family of Toluenes. These are compounds containing a benzene ring which bears a methane group.
D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens
同义名列表
57 个代谢物同义名
2,4-Diaminotoluene, monohydrochloride; 2,4-Diaminotoluene, dihydrochloride; 2,4-Diaminotoluene, 3H-labeled; 4-Methyl-1,3-phenylenediamine; 4-Methyl-1,3-benzenediamine; 4-methylbenzene-1,3-diamine; 4-Methyl-m-phenylenediamine; 2,4-Diamino-1-methylbenzene; 1,3-Diamino-4-methylbenzene; C.I. oxidation base 200; Rcra waste number u221; C.I. oxidation base 35; Pontamine developer TN; 2,4-Diamino-1-toluene; Tolylene-2,4-diamine; 4-m-Tolylenediamine; 2,4-Toluene diamine; 2,4-Tolylenediamine; Toluene-2,4-diamine; 3-Amino-p-toluidine; 5-Amino-O-toluidine; 2,4-Diaminotoluene; 2,4-Toluenediamine; m-Toluylenediamine; 2,4-Diaminotoluol; 24-Diaminotoluene; Zogen developer H; 2,4-Diaminotoluen; m-Tolylenediamine; m-Toluylendiamin; m-Toluenediamine; Brown for fur T; Developer MT-CF; Pelagol grey J; Developer DBJ; Developer MTD; Developer 14; Developer MC; 2,4-Tolamine; Developer DB; Developer MT; Fourrine 94; Developer b; Developer T; Benzofur MT; Eucanine GB; Fouramine J; Fourrine m; Tertral g; Pelagol J; Nako TMT; Zoba gke; Renal MD; 2,4-DAT; TDA; 2,4-Diaminotoluene; 2,4-Diaminotoluene
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:34237
- KEGG: C14401
- PubChem: 7261
- HMDB: HMDB0041799
- Metlin: METLIN70032
- ChEMBL: CHEMBL541230
- chemspider: 6991
- CAS: 91696-44-5
- CAS: 71111-07-4
- CAS: 95-80-7
- PMhub: MS000002159
- PubChem: 17395401
- NIKKAJI: J3.958F
- KNApSAcK: 34237
- LOTUS: LTS0116701
- wikidata: Q209195
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 9606 - Homo sapiens: -
- 5691 - Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wan-chao Zhang, Bao-feng Liu, Hui Liu, Rong-ming Miao. [Determination of 2, 4-toluenediamine in urine by gas chromatography].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2013 Dec; 31(12):939-40. doi:
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La Medicina del lavoro.
2012 Sep; 103(5):361-71. doi:
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2011 Mar; 6(1):9. doi:
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PloS one.
2011 Feb; 6(2):e14662. doi:
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International journal of molecular sciences.
2011; 12(9):6116-34. doi:
10.3390/ijms12096116. [PMID: 22016648] - Karin E Broberg, Margareta Warholm, Håkan Tinnerberg, Anna Axmon, Bo A Jönsson, Carl Johan Sennbro, Margareta Littorin, Agneta Rannug. The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.
Pharmacogenetics and genomics.
2010 Feb; 20(2):104-11. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2009 Jun; 109(2):256-64. doi:
10.1093/toxsci/kfp065. [PMID: 19332649] - Yu-Bin Ji, Chen-Feng Ji, Xiang Zou, Hui-Xin Liu. [Determination and analysis of toluene diisocyanate metabolites in mice using gas chromatography-mass spectrometry].
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The Analyst.
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Plastic and reconstructive surgery.
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Mutation research.
1997 Jul; 391(3):201-14. doi:
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Analytical chemistry.
1997 Jun; 69(11):339A. doi:
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The Analyst.
1997 Jan; 122(1):51-6. doi:
10.1039/a606148f. [PMID: 9069099] - D R Noguera, D L Freedman. Reduction and Acetylation of 2,4-Dinitrotoluene by a Pseudomonas aeruginosa Strain.
Applied and environmental microbiology.
1996 Jul; 62(7):2257-63. doi:
10.1128/aem.62.7.2257-2263.1996. [PMID: 16535348] - P Lind, M Dalene, G Skarping, L Hagmar. Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate.
Occupational and environmental medicine.
1996 Feb; 53(2):94-9. doi:
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Toxicology letters.
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Toxicology and applied pharmacology.
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Drug and chemical toxicology.
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Environmental and molecular mutagenesis.
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Biological mass spectrometry.
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Chemico-biological interactions.
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Clinical chemistry.
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