phosphamidon (BioDeep_00000002082)
代谢物信息卡片
(Z)-2-chloro-3-dimethoxyphosphoryloxy-N,N-diethyl-but-2-enamide
化学式: C10H19ClNO5P (299.0689)
中文名称: Z-磷胺, 磷胺
谱图信息:
最多检出来源 Mentha canadensis(plant) 100%
分子结构信息
SMILES: CCN(CC)C(=O)C(=C(C)OP(=O)(OC)OC)Cl
InChI: InChI=1S/C10H19ClNO5P/c1-6-12(7-2)10(13)9(11)8(3)17-18(14,15-4)16-5/h6-7H2,1-5H3/b9-8-
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:38832
- KEGG: C18689
- PubChem: 3032604
- Metlin: METLIN72468
- ChEMBL: CHEMBL1892391
- MeSH: Phosphamidon
- CAS: 23783-98-4
- CAS: 13171-21-6
- PMhub: MS000001797
- PubChem: 124489363
- KNApSAcK: 38832
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Suprabhat Mukherjee, Niladri Mukherjee, Prasanta Saini, Priya Roy, Santi P Sinha Babu. Ginger extract ameliorates phosphamidon induced hepatotoxicity.
Indian journal of experimental biology.
2015 Sep; 53(9):574-84. doi:
. [PMID: 26548077] - Prabhat Kosta, Ashish K Mehta, Amit K Sharma, Naresh Khanna, Pramod K Mediratta, Dharmendra R Mundhada, Sanvidhan Suke. Effect of piracetam and vitamin E on phosphamidon-induced impairment of memory and oxidative stress in rats.
Drug and chemical toxicology.
2013 Jan; 36(1):48-54. doi:
10.3109/01480545.2011.649093. [PMID: 22325038] - T Subramani, K S Chandrashekharaiah, N Ramachandra Swamy, K R Siddalinga Murthy. Purification and characterization of carboxylesterase from the seeds of Jatropha curcas.
The protein journal.
2012 Feb; 31(2):120-8. doi:
10.1007/s10930-011-9380-7. [PMID: 22173274] - Tanzeel Ahmed, Rahul Pathak, M D Mustafa, Rajarshi Kar, Ashok K Tripathi, Rafat S Ahmed, B D Banerjee. Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.
Environmental monitoring and assessment.
2011 Aug; 179(1-4):293-9. doi:
10.1007/s10661-010-1736-5. [PMID: 21049288] - P Thangavel, K Sumathiral, S Karthikeyan, M Ramaswamy. Endocrine response of the freshwater teleost, Sarotherodon mossambicus (Peters) to dimecron exposure.
Chemosphere.
2005 Dec; 61(8):1083-92. doi:
10.1016/j.chemosphere.2005.03.045. [PMID: 15882891] - F A Tarbah, B Kardel, S Pier, O Temme, T Daldrup. Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication.
Journal of analytical toxicology.
2004 Apr; 28(3):198-203. doi:
10.1093/jat/28.3.198. [PMID: 15107151] - C R Sahu, S Ghatak. Effects of dimecron on developing chick embryo: malformations and other histopathological changes.
Anatomia, histologia, embryologia.
2002 Feb; 31(1):15-20. doi:
10.1046/j.1439-0264.2002.00355.x. [PMID: 11841353] - C Ghosh, J N Medda. Ameliorating effects of thyroxine and atropine in phosphamidon intoxicated chick embryos.
Biomedical and environmental sciences : BES.
1999 Mar; 12(1):34-42. doi:
. [PMID: 10442219] - A M Tsatsakis, P Aguridakis, M N Michalodimitrakis, A K Tsakalov, A K Alegakis, E Koumantakis, G Troulakis. Experiences with acute organophosphate poisonings in Crete.
Veterinary and human toxicology.
1996 Apr; 38(2):101-7. doi:
. [PMID: 8693683] - C Datta, J Gupta, D Sengupta. Interaction of organophosphorus insecticides phosphamidon & malathion on lipid profile & acetylcholinesterase activity in human erythrocyte membrane.
The Indian journal of medical research.
1994 Aug; 100(?):87-9. doi:
. [PMID: 7927563] - S M Naqvi, M Hasan. Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation.
Indian journal of experimental biology.
1992 Sep; 30(9):850-2. doi:
. [PMID: 1478721] - M A Awal, J K Malik. The effect of long-term exposure to phosphamidon on the ruminal microorganisms and circulating carboxylesterase of Bubalus bubalis.
Veterinary research communications.
1992; 16(4):311-5. doi:
10.1007/bf01839330. [PMID: 1466149] - C Datta, J Gupta, A Sarkar, D Sengupta. Effects of organophosphorus insecticide phosphomidon on antioxidant defence components of human erythrocyte and plasma.
Indian journal of experimental biology.
1992 Jan; 30(1):65-7. doi:
. [PMID: 1506021] - M S Reddy, K V Rao. In vivo modification of lipid metabolism in response to phosphamidon, methylparathion and lindane exposure in the penaeid prawn, Metapenaeus monoceros.
Bulletin of environmental contamination and toxicology.
1989 Oct; 43(4):603-10. doi:
10.1007/bf01701942. [PMID: 2478234] - M A Awal, J K Malik, H S Sandhu. Measurement by spectrophotometer of blood cholinesterases inactivation following single oral doses of phosphamidon in Bubalus bubalis.
Veterinary and human toxicology.
1988 Oct; 30(5):444-6. doi:
NULL. [PMID: 3188364] - P Bhatnagar, I Soni. Evaluation of the teratogenic potential of phosphamidon in mice by gavage.
Toxicology letters.
1988 Aug; 42(2):101-7. doi:
10.1016/0378-4274(88)90066-5. [PMID: 3406954] - S M Naqvi, M Hasan, S S Haider. Neurochemical effects of phosphamidon on lipid fractions & lipid peroxidation in the rat central nervous system.
The Indian journal of medical research.
1988 Jul; 88(?):85-90. doi:
". [PMID: 3182039] - M J Coye, P G Barnett, J E Midtling, A R Velasco, P Romero, C L Clements, T G Rose. Clinical confirmation of organophosphate poisoning by serial cholinesterase analyses.
Archives of internal medicine.
1987 Mar; 147(3):438-42. doi:
NULL. [PMID: 3827420] - S S Qadri, G Usha, K Jabeen, M F Rahman, M Mustafa. Effect of dermal application of phosphamidon-92 (technical) on different tissues and hematobiochemical parameters in albino rat.
Journal of toxicology and environmental health.
1987; 20(3):273-86. doi:
10.1080/15287398709530981. [PMID: 3820340] - J Latuszyńska. [Experimental studies on the embryotoxic effect of phosphamidon on the epithelium of convoluted kidney tubules. II. Histological and histochemical studies].
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina.
1983; 38(?):117-24. doi:
NULL. [PMID: 6242837] - J Latuszyńska. [Experimental studies of the embryotoxic effect of phosphamidon on the epithelium of convoluted kidney tubules. I. Macroscopic studies].
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina.
1983; 38(?):111-6. doi:
NULL. [PMID: 6600057] - J Latuszyńska. [Experimental studies on the embryotoxic effect of phosphamidon on the epithelium of convoluted kidney tubules. III. Submicroscopic studies].
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina.
1983; 38(?):125-33. doi:
NULL. [PMID: 6600058] - E B Abdelsalam, S E Adam, G Tartour. The combined action of dieldrin and phosphamidon in goats.
Zentralblatt fur Veterinarmedizin. Reihe A.
1982 Mar; 29(2):136-41. doi:
10.1111/j.1439-0442.1982.tb01387.x. [PMID: 6810585] - S S Qadri, M Ahmad. Duration of phosphamidon-induced changes in cholinesterase activity in different organs of rats.
Indian journal of experimental biology.
1979 Apr; 17(4):423-4. doi:
NULL. [PMID: 489075] - R Bathe. A dynamic system for long-term toxicity studies in fish under laboratory conditions.
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.
1979; ?(2):417-23. doi:
10.1007/978-3-642-67265-1_49. [PMID: 288356]
