Mifepristone (BioDeep_00000002074)

 

Secondary id: BioDeep_00000405905

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one

化学式: C29H35NO2 (429.2668)
中文名称: 米非司酮
谱图信息: 最多检出来源 Homo sapiens(blood) 43.79%

分子结构信息

SMILES: CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O
InChI: InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1

描述信息

A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. [PubChem]
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03X - Other sex hormones and modulators of the genital system > G03XB - Progesterone receptor modulators
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C1891 - Progesterone Antagonist
D012102 - Reproductive Control Agents > D008600 - Menstruation-Inducing Agents
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
D012102 - Reproductive Control Agents > D000019 - Abortifacient Agents
D012102 - Reproductive Control Agents > D008186 - Luteolytic Agents

同义名列表

22 个代谢物同义名

(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one; 11-(4-DIMETHYLAMINO-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodec ahydro-cyclopenta[a]phenanthren-3-one; 11β-[4-(dimethylamino)phenyl]-17β-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one; Contragest brand OF mifepristone; Mifepristone contragest brand; Exelgyn brand OF mifepristone; Danco brand OF mifepristone; Mifepristone exelgyn brand; Mifepristone danco brand; Mifepristone (RU 486); Mifepristonum; Mifepristone; Mifepristona; Mifepriston; Mifeprex; Mifegyne; Mifégyne; Korlym; Corlux; RU-486; RU486; Mifepristone



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABCB1, AKT1, AR, CA1, ESR1, MAPK14, NR3C2, POMC, PTGS2, TP53
Peripheral membrane protein 2 ESR1, PTGS2
Endoplasmic reticulum membrane 3 CD4, NR3C2, PTGS2
Nucleus 8 AKT1, AR, ESR1, HPSE, MAPK14, NR3C2, PCNA, TP53
cytosol 7 AKT1, AR, CA1, ESR1, MAPK14, NR3C2, TP53
nuclear body 1 PCNA
centrosome 2 PCNA, TP53
nucleoplasm 8 AKT1, AR, ESR1, HPSE, MAPK14, NR3C2, PCNA, TP53
Cell membrane 5 ABCB1, AKT1, CD4, CD8A, ESR1
Cytoplasmic side 1 ESR1
lamellipodium 1 AKT1
Multi-pass membrane protein 1 ABCB1
Synapse 1 CRH
cell cortex 1 AKT1
cell surface 1 ABCB1
glutamatergic synapse 2 AKT1, MAPK14
Golgi apparatus 1 ESR1
Golgi membrane 1 INS
lysosomal membrane 1 HPSE
postsynapse 1 AKT1
Lysosome 1 HPSE
plasma membrane 6 ABCB1, AKT1, AR, CD4, CD8A, ESR1
Membrane 6 ABCB1, AKT1, AR, ESR1, HPSE, TP53
apical plasma membrane 1 ABCB1
caveola 1 PTGS2
extracellular exosome 3 ABCB1, CA1, PCNA
endoplasmic reticulum 2 PTGS2, TP53
extracellular space 7 CRH, CXCL8, HPSE, IL10, IL2, INS, POMC
lysosomal lumen 1 HPSE
mitochondrion 3 FDX1, MAPK14, TP53
protein-containing complex 5 AKT1, AR, ESR1, PTGS2, TP53
intracellular membrane-bounded organelle 1 HPSE
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 2 CD4, CD8A
Secreted 7 CRH, CXCL8, HPSE, IL10, IL2, INS, POMC
extracellular region 9 CD8A, CRH, CXCL8, HPSE, IL10, IL2, INS, MAPK14, POMC
[Isoform 2]: Secreted 1 CD8A
Mitochondrion matrix 2 FDX1, TP53
mitochondrial matrix 2 FDX1, TP53
transcription regulator complex 2 ESR1, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
external side of plasma membrane 2 CD4, CD8A
varicosity 1 CRH
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
Early endosome 1 CD4
cell-cell junction 1 AKT1
vesicle 1 AKT1
Apical cell membrane 1 ABCB1
Membrane raft 2 CD4, HPSE
Cytoplasm, cytoskeleton 1 TP53
spindle 1 AKT1
extracellular matrix 1 HPSE
Nucleus, PML body 1 TP53
PML body 1 TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 1 POMC
nuclear speck 2 AR, MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 2 CD8A, NR3C2
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 5 AR, ESR1, NR3C2, PCNA, TP53
spindle pole 1 MAPK14
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
site of double-strand break 1 TP53
endosome lumen 1 INS
euchromatin 1 ESR1
germ cell nucleus 1 TP53
replication fork 2 PCNA, TP53
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 3 INS, MAPK14, POMC
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 CD4, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
male germ cell nucleus 1 PCNA
specific granule lumen 1 HPSE
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 1]: Nucleus 2 ESR1, TP53
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 CD8A
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
T cell receptor complex 2 CD4, CD8A
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA


文献列表

  • Takeshi Hashimoto, Katsuya Hirano. Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells. Cellular & molecular biology letters. 2024 Mar; 29(1):45. doi: 10.1186/s11658-024-00559-9. [PMID: 38553665]
  • Jan Kroon, Max Gentenaar, Tijmen J A Moll, Hazel Hunt, Onno C Meijer. Glucocorticoid receptor modulator CORT125385 alleviates diet-induced hepatosteatosis in male and female mice. European journal of pharmacology. 2023 Aug; ?(?):176012. doi: 10.1016/j.ejphar.2023.176012. [PMID: 37634839]
  • Li Zhang, Shuhui Wang, Yucong Ma, Yajing Song, Dandan Li, Xiao Liang, Yanzhi Hao, Min Jiang, Jingfang Lv, Huilan Du. Shoutai Wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice. Journal of ethnopharmacology. 2023 Aug; 312(?):116502. doi: 10.1016/j.jep.2023.116502. [PMID: 37068718]
  • Jing Sun, Wenhua Xu, Han Ye, Dingzhong Tang, Yan Jiang, Yuqing Kang, Jianchun Pan, Junfeng Zhu, Min Zhou, Ling Chen. Stress induces prolonged pain recovery after surgery: involvement of glucocorticoid related pathway. The international journal of neuropsychopharmacology. 2023 Mar; ?(?):. doi: 10.1093/ijnp/pyad010. [PMID: 36905195]
  • Yiming Lei, Lili Yang, Honglian Yang, Min Li, Li Ou, Yang Bai, Taiwei Dong, Feng Gao, Peifeng Wei. The efficacy and safety of Chinese herbal medicine Guizhi Fuling capsule combined with low dose mifepristone in the treatment of uterine fibroids: a systematic review and meta-analysis of 28 randomized controlled trials. BMC complementary medicine and therapies. 2023 Feb; 23(1):54. doi: 10.1186/s12906-023-03842-y. [PMID: 36803997]
  • Gary N Landis, Hans S Bell, Oscar Peng, Brett Bognar, Andy Tong, Tomás D Manea, Hanmei Bao, Xianlin Han, John Tower. Dhr96[1] mutation and maternal tudor[1] mutation increase life span and reduce the beneficial effects of mifepristone in mated female Drosophila. PloS one. 2023; 18(12):e0292820. doi: 10.1371/journal.pone.0292820. [PMID: 38127988]
  • Gary N Landis, Sebastian Ko, Oscar Peng, Brett Bognar, Michael Khmelkov, Hans S Bell, John Tower. A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects. Fly. 2022 12; 16(1):397-413. doi: 10.1080/19336934.2022.2149209. [PMID: 36412257]
  • Carolyn M Bauer, Michelle A Oranges, Gaylinn Firempong, L Michael Romero. Corticosterone Alters Body Weight, but Not Metabolites, during Chronic Stress. Physiological and biochemical zoology : PBZ. 2022 Nov; 95(6):465-473. doi: 10.1086/721297. [PMID: 36001889]
  • Zhang Tiantian, L I Guowen, Chu Zhifeng, L I Jie, Y U Lijun, Gao Yuan, Wang Huifeng. Efficacy of Qiancao () and Haipiaoxiao (), a traditional Chinese herb pair, on abnormal uterine bleeding in rats with incomplete abortion. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2022 10; 42(5):758-763. doi: 10.19852/j.cnki.jtcm.20220707.002. [PMID: 36083483]
  • Li-Li Li, Qi Huang, Jia-Jia Qi, Min Yao, Dai-Yin Peng. [Simultaneous determination and pharmacokinetic study of five compounds from total extract of Clinopodium chinense in abnormal uterine bleeding rat plasma by UPLC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Sep; 47(18):5071-5078. doi: 10.19540/j.cnki.cjcmm.20220421.702. [PMID: 36164917]
  • Mengru Bai, Mingyang Chen, Qingquan Zeng, Shuanghui Lu, Ping Li, Zhiyuan Ma, Nengming Lin, Caihong Zheng, Hui Zhou, Su Zeng, Dongli Sun, Huidi Jiang. Up-regulation of hepatic CD36 by increased corticosterone/cortisol levels via GR leads to lipid accumulation in liver and hypertriglyceridaemia during pregnancy. British journal of pharmacology. 2022 09; 179(17):4440-4456. doi: 10.1111/bph.15863. [PMID: 35491243]
  • John Joseph Reynolds-Wright, Anne Johnstone, Karen McCabe, Emily Evans, Sharon Cameron. Adherence to treatment and prevalence of side effects when medical abortion is delivered via telemedicine: a prospective observational cohort study during COVID-19. BMJ sexual & reproductive health. 2022 07; 48(3):185-192. doi: 10.1136/bmjsrh-2021-201263. [PMID: 34711647]
  • Mingyang Chen, Mengru Bai, Yaodong Yi, Shuanghui Lu, Jun Luo, Ping Li, Hengbin Zhang, Huidi Jiang, Hui Zhou. Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice. Toxicology letters. 2022 Jun; 363(?):1-10. doi: 10.1016/j.toxlet.2022.05.003. [PMID: 35589016]
  • Katherine C Whitehouse, Tara Shochet, Patricia A Lohr. Efficacy of a low-sensitivity urine pregnancy test for identifying ongoing pregnancy after medication abortion at 64 to 70 days of gestation. Contraception. 2022 06; 110(?):21-26. doi: 10.1016/j.contraception.2022.02.005. [PMID: 35259410]
  • Claire Stenhouse, Katherine M Halloran, Robyn M Moses, Heewon Seo, Dana Gaddy, Gregory A Johnson, Guoyao Wu, Larry J Suva, Fuller W Bazer. Effects of progesterone and interferon tau on ovine endometrial phosphate, calcium, and vitamin D signaling†. Biology of reproduction. 2022 05; 106(5):888-899. doi: 10.1093/biolre/ioac027. [PMID: 35134855]
  • Chen-Cheng Lin, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Liu. Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention. International journal of molecular sciences. 2022 May; 23(10):. doi: 10.3390/ijms23105494. [PMID: 35628305]
  • Renli Ye, Yan Jiang. Efficacy of mifepristone plus Shenqi Yangxue Granulesfor hysteromyoma complicated with anemia and its effect on hemoglobin, erythrocytes and hematocrit. Pakistan journal of pharmaceutical sciences. 2022 May; 35(3(Special)):905-910. doi: ". [PMID: 35791586]
  • L L Wu, H Y Zeng, X Y Tang, G J Fan. [Mifepristone in the treatment of an elderly patient with adrenocorticotropic hormone-dependent Cushing syndrome]. Zhonghua nei ke za zhi. 2022 May; 61(5):574-577. doi: 10.3760/cma.j.cn112138-20210709-00469. [PMID: 35488612]
  • Lauren J Ralph, Katherine Ehrenreich, Rana Barar, M Antonia Biggs, Natalie Morris, Kelly Blanchard, Nathalie Kapp, Ghazaleh Moayedi, Jamila Perritt, Elizabeth G Raymond, Kari White, Daniel Grossman. Accuracy of self-assessment of gestational duration among people seeking abortion. American journal of obstetrics and gynecology. 2022 05; 226(5):710.e1-710.e21. doi: 10.1016/j.ajog.2021.11.1373. [PMID: 34922922]
  • Ushma D Upadhyay, Elizabeth G Raymond, Leah R Koenig, Leah Coplon, Marji Gold, Bliss Kaneshiro, Christy M Boraas, Beverly Winikoff. Outcomes and Safety of History-Based Screening for Medication Abortion: A Retrospective Multicenter Cohort Study. JAMA internal medicine. 2022 05; 182(5):482-491. doi: 10.1001/jamainternmed.2022.0217. [PMID: 35311911]
  • Suji Uhm, Namrata Mastey, Courtney C Baker, Melissa J Chen, Melissa C Matulich, Melody Y Hou, Juliana Melo, Susan F Wilson, Mitchell D Creinin. Mifepristone prior to osmotic dilators for dilation and evacuation cervical preparation: A randomized, double-blind, placebo-controlled pilot study. Contraception. 2022 03; 107(?):23-28. doi: 10.1016/j.contraception.2021.08.013. [PMID: 34464634]
  • S-S Yu, M-Y Ma, R Zhou, R Liang, Z Duan, J Wang, Y Tian, J Jiang, X He, Q Zhou. Methotrexate/mifepristone-combined with embryo removal in the treatment of caesarean scar pregnancy. European review for medical and pharmacological sciences. 2022 03; 26(6):1984-1993. doi: 10.26355/eurrev_202203_28347. [PMID: 35363349]
  • Lauren Vogel, Greg Basky. How the pandemic is transforming abortion access. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2022 02; 194(6):E223. doi: 10.1503/cmaj.1095986. [PMID: 35165137]
  • Rita Rubin. Expanding Access to Medication Abortions. JAMA. 2022 Jan; 327(2):112-114. doi: 10.1001/jama.2021.23357. [PMID: 34935858]
  • Shi-Jie Bi, Yu-Xi Huang, Li-Mei Feng, Shi-Jun Yue, Yan-Yan Chen, Rui-Jia Fu, Ding-Qiao Xu, Yu-Ping Tang. Network pharmacology-based study on immunomodulatory mechanism of danggui-yimucao herb pair for the treatment of RU486-induced abortion. Journal of ethnopharmacology. 2022 Jan; 282(?):114609. doi: 10.1016/j.jep.2021.114609. [PMID: 34508802]
  • Intan Sofia Omar, Amira Hajirah Abd Jamil, Noor Azmi Mat Adenan, Ivy Chung. MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling. PloS one. 2022; 17(7):e0270830. doi: 10.1371/journal.pone.0270830. [PMID: 35816477]
  • Hongli Huang, Lei Xia, Yanqiu Xia, Yunping Yan, Zhuojun Jiang, Pei Zhao, Li Dong. Tiaojing Cuyun Recipe Enhances Pregnancy Outcome via the VEGF/PI3K/AKT/eNOS Signaling Pathway in EID Mice. Disease markers. 2022; 2022(?):9461444. doi: 10.1155/2022/9461444. [PMID: 35251378]
  • Ikuro Takakura, Tomoyuki Kishida, Ryohei Yokoi, Shinji Souma. Estradiol dominance induces hemodilution and mild hematological alterations in mifepristone-treated rats. The Journal of toxicological sciences. 2022; 47(7):301-308. doi: 10.2131/jts.47.301. [PMID: 35786681]
  • Heidi Moseson, Ruvani Jayaweera, Ijeoma Egwuatu, Belén Grosso, Ika Ayu Kristianingrum, Sybil Nmezi, Ruth Zurbriggen, Relebohile Motana, Chiara Bercu, Sofía Carbone, Caitlin Gerdts. Effectiveness of self-managed medication abortion with accompaniment support in Argentina and Nigeria (SAFE): a prospective, observational cohort study and non-inferiority analysis with historical controls. The Lancet. Global health. 2022 01; 10(1):e105-e113. doi: 10.1016/s2214-109x(21)00461-7. [PMID: 34801131]
  • Shasha Shi, Qiaobo Ye, Chenghao Yu, Fu Peng. The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis. Journal of ethnopharmacology. 2021 Dec; 281(?):114551. doi: 10.1016/j.jep.2021.114551. [PMID: 34428523]
  • Chenhao Bi, Mingqi Qiao, Yuqi Jia, Haijun Wang. Network meta-analysis of 6 kinds of Chinese patent medicines combined with mifepristone in the treatment of uterine fibroids: A protocol for systematic review and network meta-analysis. Medicine. 2021 Oct; 100(42):e27523. doi: 10.1097/md.0000000000027523. [PMID: 34678886]
  • Jiangang Cao, Yawen Chen, Xuan Xia, Hui Qu, Ying Ao, Hui Wang. Intergenerational genetic programming mechanism and sex differences of the adrenal corticosterone synthesis dysfunction in offspring induced by prenatal ethanol exposure. Toxicology letters. 2021 Oct; 351(?):78-88. doi: 10.1016/j.toxlet.2021.08.007. [PMID: 34454011]
  • N Boydell, J J Reynolds-Wright, S T Cameron, J Harden. Women's experiences of a telemedicine abortion service (up to 12 weeks) implemented during the coronavirus (COVID-19) pandemic: a qualitative evaluation. BJOG : an international journal of obstetrics and gynaecology. 2021 10; 128(11):1752-1761. doi: 10.1111/1471-0528.16813. [PMID: 34138505]
  • John Joseph Reynolds-Wright, Anne Johnstone, Karen McCabe, Emily Evans, Sharon Cameron. Telemedicine medical abortion at home under 12 weeks' gestation: a prospective observational cohort study during the COVID-19 pandemic. BMJ sexual & reproductive health. 2021 10; 47(4):246-251. doi: 10.1136/bmjsrh-2020-200976. [PMID: 33542062]
  • Signe Brinch, Philip Hansen, Peter Larvad, Mikael Ploug Boesen, Michael Ringdom Krogsgaard. [Clinical and diagnostic-imaging findings in patellofemoral instability]. Ugeskrift for laeger. 2021 09; 183(39):. doi: NULL. [PMID: 34596513]
  • Ervin Kallfa, Finn Friis Lauszus, Pernille Ravn. [Control of the level of human chorionic gonadotropin in urine compared to the level of serum after medically provoked abortion is a safe alternative]. Ugeskrift for laeger. 2021 09; 183(38):. doi: NULL. [PMID: 34596518]
  • Xiaohan Gong, Shiyun Dai, Tingting Wang, Jinzhi Zhang, Guanlan Fan, Mingcui Luo, Yiwen Yi, Hui Wang, Dianxiang Lu, Dan Xu. MiR-17-5p/FOXL2/CDKN1B signal programming in oocytes mediates transgenerational inheritance of diminished ovarian reserve in female offspring rats induced by prenatal dexamethasone exposure. Cell biology and toxicology. 2021 Sep; ?(?):. doi: 10.1007/s10565-021-09645-6. [PMID: 34537908]
  • Guglielmo Stabile, Federico Romano, Giulia Zinicola, Ghergana Alexandrova Topouzova, Giovanni Di Lorenzo, Francesco Paolo Mangino, Giuseppe Ricci. Interstitial Ectopic Pregnancy: The Role of Mifepristone in the Medical Treatment. International journal of environmental research and public health. 2021 09; 18(18):. doi: 10.3390/ijerph18189781. [PMID: 34574706]
  • Wing Kay Fok, Klaira Lerma, Kate A Shaw, Paul D Blumenthal. Comparison of two home pregnancy tests for self-confirmation of medication abortion status: A randomized trial. Contraception. 2021 09; 104(3):296-300. doi: 10.1016/j.contraception.2021.05.003. [PMID: 33992610]
  • Sarah Munro, Kate Wahl, Judith A Soon, Edith Guilbert, Elizabeth S Wilcox, Genevieve Leduc-Robert, Nadra Ansari, Courtney Devane, Wendy V Norman. Pharmacist dispensing of the abortion pill in Canada: Diffusion of Innovation meets integrated knowledge translation. Implementation science : IS. 2021 08; 16(1):76. doi: 10.1186/s13012-021-01144-w. [PMID: 34344393]
  • Ushma D Upadhyay, Leah R Koenig, Karen R Meckstroth. Safety and Efficacy of Telehealth Medication Abortions in the US During the COVID-19 Pandemic. JAMA network open. 2021 08; 4(8):e2122320. doi: 10.1001/jamanetworkopen.2021.22320. [PMID: 34427682]
  • Jaclyn J Serpico. Abortion exceptionalism and the mifepristone REMS. Contraception. 2021 07; 104(1):8-11. doi: 10.1016/j.contraception.2021.03.031. [PMID: 33831445]
  • Erica Chong, Tara Shochet, Elizabeth Raymond, Ingrida Platais, Holly A Anger, Shandhini Raidoo, Reni Soon, Melissa S Grant, Susan Haskell, Kristina Tocce, Maureen K Baldwin, Christy M Boraas, Paula H Bednarek, Joey Banks, Leah Coplon, Francine Thompson, Esther Priegue, Beverly Winikoff. Expansion of a direct-to-patient telemedicine abortion service in the United States and experience during the COVID-19 pandemic. Contraception. 2021 07; 104(1):43-48. doi: 10.1016/j.contraception.2021.03.019. [PMID: 33781762]
  • Alice Mark, Angel M Foster, Jamila Perritt. The future of abortion is now: Mifepristone by mail and in-clinic abortion access in the United States. Contraception. 2021 07; 104(1):38-42. doi: 10.1016/j.contraception.2021.03.033. [PMID: 33844980]
  • Courtney Kerestes, Sarah Murayama, Jasmine Tyson, Melissa Natavio, Elisabeth Seamon, Shandhini Raidoo, Lea Lacar, Emory Bowen, Reni Soon, Ingrida Platais, Bliss Kaneshiro, Paris Stowers. Provision of medication abortion in Hawai'i during COVID-19: Practical experience with multiple care delivery models. Contraception. 2021 07; 104(1):49-53. doi: 10.1016/j.contraception.2021.03.025. [PMID: 33789080]
  • Elizabeth G Raymond, Holly A Anger, Erica Chong, Sue Haskell, Melissa Grant, Christy Boraas, Kristina Tocce, Joey Banks, Bliss Kaneshiro, Maureen K Baldwin, Leah Coplon, Paula Bednarek, Tara Shochet, Ingrida Platais. 'False positive' urine pregnancy test results after successful medication abortion. Contraception. 2021 06; 103(6):400-403. doi: 10.1016/j.contraception.2021.02.004. [PMID: 33596414]
  • Martina Feger, Franz Ewendt, Jörg Strotmann, Holger Schäffler, Daniela Kempe-Teufel, Philipp Glosse, Gabriele I Stangl, Michael Föller. Glucocorticoids dexamethasone and prednisolone suppress fibroblast growth factor 23 (FGF23). Journal of molecular medicine (Berlin, Germany). 2021 05; 99(5):699-711. doi: 10.1007/s00109-021-02036-8. [PMID: 33517471]
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