Methidathion (BioDeep_00001873568)
代谢物信息卡片
Methidathion
化学式: C6H11N2O4PS3 (301.9619)
中文名称: 杀扑磷, 甲硫磷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=NN(C(=O)S1)CSP(=S)(OC)OC
InChI: InChI=1S/C6H11N2O4PS3/c1-10-5-7-8(6(9)16-5)4-15-13(14,11-2)12-3/h4H2,1-3H3
描述信息
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
3 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:34837
- PubChem: 13709
- ChEMBL: CHEMBL226651
- CAS: 950-37-8
- RefMet: Methidathion
- KEGG: C14431
- PubChem: 17395431
- KNApSAcK: 34837
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yoshikazu Yamagishi, Sayaka Nagasawa, Hirotaro Iwase, Yasumitsu Ogra. Post-mortem interaction between methidathion and human serum albumin in blood.
The Journal of toxicological sciences.
2022; 47(4):139-146. doi:
10.2131/jts.47.139. [PMID: 35370241] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Nahit Gençer, Emre Yavuz. An alternative purification method for human serum paraoxonase 1 and its interaction with methidathion.
Archives of physiology and biochemistry.
2017 Jul; 123(3):159-164. doi:
10.1080/13813455.2017.1279632. [PMID: 28276711] - Xiang Wei, Yiou Pan, Xuecheng Xin, Chao Zheng, Xiwu Gao, Jinghui Xi, Qingli Shang. Cross-resistance pattern and basis of resistance in a thiamethoxam-resistant strain of Aphis gossypii Glover.
Pesticide biochemistry and physiology.
2017 May; 138(?):91-96. doi:
10.1016/j.pestbp.2017.03.007. [PMID: 28456311] - Yaping Jiang, Takayuki Shibamoto, Yanjie Li, Canping Pan. Effect of household and commercial processing on acetamiprid, azoxystrobin and methidathion residues during crude rapeseed oil production.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2013; 30(7):1279-86. doi:
10.1080/19440049.2013.796094. [PMID: 23756237] - Tatsunori Takayasu, Yuko Ishida, Mizuho Nosaka, Mariko Kawaguchi, Yumi Kuninaka, Akihiko Kimura, Toshikazu Kondo. High concentration of methidathion detected in a fatal case of organophosphate-poisoning.
Legal medicine (Tokyo, Japan).
2012 Sep; 14(5):263-6. doi:
10.1016/j.legalmed.2012.04.007. [PMID: 22704879] - Idriss Bakas, Najwa Ben Oujji, Ewa Moczko, Georges Istamboulie, Sergey Piletsky, Elena Piletska, Ihya Ait-Ichou, Elhabib Ait-Addi, Thierry Noguer, Régis Rouillon. Molecular imprinting solid phase extraction for selective detection of methidathion in olive oil.
Analytica chimica acta.
2012 Jul; 734(?):99-105. doi:
10.1016/j.aca.2012.05.013. [PMID: 22704478] - Najwa Ben Oujji, Idriss Bakas, Georges Istamboulié, Ihya Ait-Ichou, Elhabib Ait-Addi, Régis Rouillon, Thierry Noguer. Acetylcholinesterase immobilized on magnetic beads for pesticides detection: application to olive oil analysis.
Sensors (Basel, Switzerland).
2012; 12(6):7893-904. doi:
10.3390/s120607893. [PMID: 22969377] - Youmie Park, A-Rang Im, Yoo Na Hong, Chong-Kook Kim, Yeong Shik Kim. Detection of malathion, fenthion and methidathion by using heparin-reduced gold nanoparticles.
Journal of nanoscience and nanotechnology.
2011 Sep; 11(9):7570-8. doi:
10.1166/jnn.2011.5123. [PMID: 22097460] - Bochra Gargouri, Riadh Ben Mansour, Fatma Ben Abdallah, Abdelfetteh Elfekih, Saloua Lassoued, Hamden Khaled. Protective effect of quercetin against oxidative stress caused by dimethoate in human peripheral blood lymphocytes.
Lipids in health and disease.
2011 Aug; 10(?):149. doi:
10.1186/1476-511x-10-149. [PMID: 21861917] - Siva K Nalabotu, Madhukar B Kolli, William E Triest, Jane Y Ma, Nandini D P K Manne, Anjaiah Katta, Hari S Addagarla, Kevin M Rice, Eric R Blough. Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats.
International journal of nanomedicine.
2011; 6(?):2327-35. doi:
10.2147/ijn.s25119. [PMID: 22072870] - N Stamatis, D Hela, I Konstantinou. Pesticide inputs from the sewage treatment plant of Agrinio to River Acheloos, western Greece: occurrence and removal.
Water science and technology : a journal of the International Association on Water Pollution Research.
2010; 62(5):1098-105. doi:
10.2166/wst.2010.932. [PMID: 20818051] - Stergios G Papastergiou, Nikolaos E Koukoulias, Evangelos Ziogas, Theofilos Dimitriadis, Panagiotis Koumis. Spontaneous, bilateral, quadriceps tendon rupture caused by local exposure to methidathion.
BMJ case reports.
2009; 2009(?):. doi:
10.1136/bcr.09.2009.2256. [PMID: 22114623] - Xiaofei Zhang, Jeffrey H Driver, Yanhong Li, John H Ross, Robert I Krieger. Dialkylphosphates (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment.
Journal of agricultural and food chemistry.
2008 Nov; 56(22):10638-45. doi:
10.1021/jf8018084. [PMID: 18947233] - Edwar Fuentes, María E Báez, Adalí Quiñones. Suitability of microwave-assisted extraction coupled with solid-phase extraction for organophosphorus pesticide determination in olive oil.
Journal of chromatography. A.
2008 Oct; 1207(1-2):38-45. doi:
10.1016/j.chroma.2008.08.051. [PMID: 18774576] - Mehmet Güney, Hilmi Demirin, Baha Oral, Meltem Ozgüner, Gökhan Bayhan, Irfan Altuntas. Ovarian toxicity in rats caused by methidathion and ameliorating effect of vitamins E and C.
Human & experimental toxicology.
2007 Jun; 26(6):491-8. doi:
10.1177/0960327106077505. [PMID: 17698944] - Shigeaki Inoue, Takeshi Saito, Hiroyasu Mase, Yosuke Suzuki, Kensuke Takazawa, Isotoshi Yamamoto, Sadaki Inokuchi. Rapid simultaneous determination for organophosphorus pesticides in human serum by LC-MS.
Journal of pharmaceutical and biomedical analysis.
2007 May; 44(1):258-64. doi:
10.1016/j.jpba.2007.01.036. [PMID: 17337150] - P Georgakopoulos, E Foteinopoulou, P Athanasopoulos, E Drosinos, P Skandamis. Recoveries of four representative organophosphorus pesticides from 18 plant products belonging to different botanical categories: implications for matrix effects.
Food additives and contaminants.
2007 Apr; 24(4):360-8. doi:
10.1080/02652030601101144. [PMID: 17454109] - F K Mohammad, A S Alias, O A H Ahmed. Electrometric measurement of plasma, erythrocyte, and whole blood cholinesterase activities in healthy human volunteers.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2007 Mar; 3(1):25-30. doi:
10.1007/bf03161035. [PMID: 18072155] - R Sutcu, I Altuntas, B Yildirim, N Karahan, H Demirin, N Delibas. The effects of subchronic methidathion toxicity on rat liver: role of antioxidant vitamins C and E.
Cell biology and toxicology.
2006 May; 22(3):221-7. doi:
10.1007/s10565-006-0039-7. [PMID: 16583303] - Eloisa Caldas, Andreia Jardim, Arpad Ambrus, Luiz Cesar Souza. Variability of organophosphorus insecticide residues in large size crops grown in commercial farms in Brazil.
Food additives and contaminants.
2006 Feb; 23(2):148-58. doi:
10.1080/02652030500479708. [PMID: 16449057] - K J Min, C G Cha, W Popendorf. Determination of urinary metabolites of phosalone, methidathion, and IBP after oral administration and dermal application to rats.
Bulletin of environmental contamination and toxicology.
2005 May; 74(5):809-16. doi:
10.1007/s00128-005-0653-8. [PMID: 16097311] - Turhan Yavuz, Namik Delibas, Bekir Yildirim, Irfan Altuntas, Ozden Candir, Ahmet Cora, Nermin Karahan, Erdogan Ibrisim, Ali Kutsal. Vascular wall damage in rats induced by organophosphorus insecticide methidathion.
Toxicology letters.
2005 Jan; 155(1):59-64. doi:
10.1016/j.toxlet.2004.08.012. [PMID: 15585360] - Turhan Yavuz, Namik Delibas, Bekir Yildirim, Irfan Altuntas, Ozden Candir, Ahmet Cora, Nermin Karaman, Erdogan Ibrisim, Ali Kutsal. Vascular wall damage in rats induced by methidathion and ameliorating effect of vitamins E and C.
Archives of toxicology.
2004 Nov; 78(11):655-9. doi:
10.1007/s00204-004-0593-9. [PMID: 15368089] - Turhan Yavuz, Irfan Altuntas, Namik Delibas, Bekir Yildirim, Ozden Candir, Ahmet Corâ, Nermin Karahan, Erdogan Ibrisim, Ali Kutsal. Cardiotoxicity in rats induced by methidathion and ameliorating effect of vitamins E and C.
Human & experimental toxicology.
2004 Jul; 23(7):323-9. doi:
10.1191/0960327104ht456oa. [PMID: 15311849] - E Romero-Taboada, G Dios Cancela. Methidathion complexes with homoionic and surfactant-modified montmorillonites.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2004 May; 39(4):551-64. doi:
10.1081/pfc-200026781. [PMID: 15473636] - Estefanía Rodríguez, Mercedes Campos, Aniceto J Sánchez Raya, Aránzazu Peña. Effect of the combined treatment of insecticides and an attractant for the control of Phloeotribus scarabaeoides, a pest of Olea europea.
Pest management science.
2003 Mar; 59(3):339-46. doi:
10.1002/ps.643. [PMID: 12639052] - Bozena Morzycka. Simple method for the determination of trace levels of pesticides in honeybees using matrix solid-phase dispersion and gas chromatography.
Journal of chromatography. A.
2002 Dec; 982(2):267-73. doi:
10.1016/s0021-9673(02)01505-4. [PMID: 12489883] - I Altuntas, N Delibas, R Sutcu. The effects of organophosphate insecticide methidathion on lipid peroxidation and anti-oxidant enzymes in rat erythrocytes: role of vitamins E and C.
Human & experimental toxicology.
2002 Dec; 21(12):681-5. doi:
10.1191/0960327102ht304oa. [PMID: 12540039] - Tomonori Arao, Chiaki Fuke, Hajime Takaesu, Yasumasa Morinaga, Tetsuji Miyazaki. A case of fatal trichlorfon and methidathion poisoning.
Legal medicine (Tokyo, Japan).
2002 Sep; 4(3):182-6. doi:
10.1016/s1344-6223(02)00014-7. [PMID: 12935667] - Irfan Altuntas, Namik Delibas, Mustafa Demirci, Ibrahim Kilinc, Numan Tamer. The effects of methidathion on lipid peroxidation and some liver enzymes: role of vitamins E and C.
Archives of toxicology.
2002 Aug; 76(8):470-3. doi:
10.1007/s00204-002-0359-1. [PMID: 12185416] - Richard A Fenske, Golan Kedan, Chensheng Lu, Jennifer A Fisker-Andersen, Cynthia L Curl. Assessment of organophosphorous pesticide exposures in the diets of preschool children in Washington State.
Journal of exposure analysis and environmental epidemiology.
2002 Jan; 12(1):21-8. doi:
10.1038/sj.jea.7500197. [PMID: 11859430] - R I Krieger, T M Dinoff, S Korpalski, J Peterson. Protectiveness of Kleengard(R) LP and Tyvek(R)-Saranex(R) 23-P during mixing/loading and airblast application in treefruits.
Bulletin of environmental contamination and toxicology.
1998 Oct; 61(4):455-61. doi:
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1993 Apr; 40(4):284-90. doi:
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1992 Aug; 19(2):307-14. doi:
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